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      • KCI등재

        Association of Blood Pressure at Specific Time-Points with 1-Year Renal Outcomes in Patients with Diabetic Chronic Kidney Disease

        류지원,Ran-hui Cha,Hajeong Lee,Yon Su Kim,Jung Pyo Lee,Young Rim Song,김성균,Sejoong Kim 전해질고혈압연구회 2019 Electrolytes & Blood Pressure Vol.17 No.2

        Background: The 24-hour mean blood pressure (mBP) is the best predictor of organ damage; however, it is not easily applicable in clinical practice. The APrODiTe study suggested that systolic blood pressure (SBP) values at 7:00 AM and 9:30 PM were associated with the 24-hour mSBP in patients with chronic kidney disease (CKD). We investigated the association of the SBP values at these time-points with the renal outcomes in patients with diabetic CKD during 1-year follow-up. Methods: Ninety-six patients with diabetic CKD were included at 1-year follow-up. The renal outcomes were an increase in the random urine protein/creatinine ratio or estimated glomerular filtration rate (eGFR) deterioration, which means a decrease in eGFR ≥5 mL/min/1.73 m2 compared to the baseline values. Results: The baseline SBP values at 7:00 AM, and 9:30 PM, and the 24-hour mSBP were 135.6±24.9 mmHg, 141.7±25.6 mmHg, and 136.4±20.7 mmHg, respectively. The SBP values measured at the same time-points after 1 year were similar to those at baseline. The SBP at 7:00 AM was significantly associated with eGFR deterioration in the univariate and multivariate analyses (odds ratio [OR]: 1.032; 95% confidence interval [CI]: 1.006- 1.059; p=0.016). The SBP at 7:00AM and 24-hour mSBP did not show a concordant association with sustained proteinuria in the linear and logistic analyses. In the subgroup analysis, the association between the SBP at 7:00 AM and eGFR deterioration persisted in patients with CKD stage 3-5 (OR: 1.041; 95% CI: 1.010-1.073; p=0.010). Conclusion: The SBP at 7:00 AM, in addition to the 24-hour mSBP, is also associated with eGFR deterioration in patients with diabetic CKD, particularly in those with CKD stage 3-5.

      • 한국 3개 지역(서울, 인천, 광주)의 PM<SUB>2.5</SUB> 화학성분 분석과 PMF 모델 적용을 통한 오염원 특성 비교

        류지원,유일한,김태연,정연승,이승묵,전권호,임재현 한국대기환경학회 2021 한국대기환경학회 학술대회논문집 Vol.2021 No.10

        국내 초미세먼지에 대한 효과적인 저감 및 관리대책을 마련하기 위해서는 국내에서 발생하는 주요 오염원을 추적하여 관리하는 것은 중요하다. 또한, 우리나라는 중국과 몽골 등의 풍하지역에 위치하기 때문에 장거리 이동에 따른 국외 영향을 파악하는 것도 중요하다. 따라서 본 연구는 서울지역과 한반도 서부지역에 위치하고 인구 밀도가 높은 두 광역시(인천, 광주)의 PM2.5 화학성분 분석 결과를 활용하여 지역 특성에 따른 초미세먼지 오염원과 국외 영향을 파악하는 것이 목적이다. Positive Matrix Factorization (PMF) 모델을 사용하여 지역별 주요 오염원을 도출하고 정량적 기여도를 계산하였다. 그리고 도출한 오염원 기여도를 활용하여 Conditional Probability Function (CPF) 모델을 사용하였고, 이를 통해 지역별 국지적 오염원의 위치를 확인하였다. 이후 Potential Source Contribution Function (PSCF) 모델을 사용하여 지역별 장거리 이동 특성을 반영한 잠재적인 오염 가능 지점을 도출하였다. 위의 방법으로 도출한 지역별 결과를 바탕으로 지역 특성에 따른 PM2.5 오염원의 특성을 파악하였다.

      • KCI등재

        Comparison of dominant and nondominant C3 deposition in primary glomerulonephritis

        류지원,백은지,손형은,지영,정종철,김세중,나기영,채동완,김성표,김수환,지종현,장태익,최범순,진호준 대한신장학회 2023 Kidney Research and Clinical Practice Vol.42 No.1

        Background: Alternative complement pathway dysregulation plays a key role in glomerulonephritis (GN) and is associated with C3 deposition. Herein, we examined pathological and clinical differences between cases of primary GN with C3-dominant (C3D-GN) and nondominant (C3ND-GN) deposition. Methods: We extracted primary GN data from the Korean GlomeruloNEphritis sTudy (KoGNET). C3D-GN was defined as C3 staining two grades greater than C1q, C4, and immunoglobulin via immunofluorescence analysis. To overcome a large difference in the number of patients between the C3D-GN and C3ND-GN groups (50 vs. 13,070), permutation testing was used for analysis.Results: The C3D-GN group exhibited higher serum creatinine (p ≤ 0.001), a greater prevalence of estimated glomerular filtration rate of <60 mL/min/1.72 m2 (p ≤ 0.001), higher (but not significantly so) C-reactive protein level, and lower serum C3 level (p ≤ 0.001). Serum albumin, urine protein/creatinine ratio, number of patients who progressed to end-stage renal disease, and all-cause mortality were comparable between groups. Interstitial fibrosis and mesangial cellularity were greater in the C3D-GN group (p = 0.04 and p = 0.01, respectively) than in the C3ND-GN group. C3 deposition was dominant in the former group (p < 0.001), in parallel with increased subendothelial deposition (p ≤ 0.001). Conclusion: Greater progression of renal injury and higher mortality occurred in patients with C3D-GN than with C3ND-GN, along with pathologic differences in interstitial and mesangial changes.

      • KCI등재
      • KCI등재
      • KCI등재

        헤어 디자인의 구성원리 및 원랭스 커트에 대한 고찰

        류지원,소영진 한국미용학회 2000 한국미용학회지 Vol.6 No.1

        One Length Cut, one of the various kinds of cutting technique, is a basic, simple and past process. That is not pick up strand but slick down one's hair, and then cutting without layer according to the one length guidelines The process of shaping hair style in One Length Cut is monotonous, but desired very correction. Therefore It is matter of general knowledge that this technique is somewhat to be particular for fundametal hair designers as well as experienced one. Seize principles of making hair design and judge applicable hair style. and then One Length Cut reachs completion by following procedure: 1. Unterstand that patron wants hiar style. 2. Make a plan quickly in considering of feature, age, thickness, density. 3. Shape hair style concretly according to that. 4. Review hair style on the ground of observation and give the finishing touches to points that symmetry is not enough. If hair style completed by this procedure have no artistic craftsmanship, perfect hair style is not accomplished in the true sense of the word. So hair designers exert ceaseless all possible efforts to obtain deep knowledge and experience, and to upgrade technical disposition.

      • KCI등재

        고구려 고분벽화에 나타난 두식의 조형양식

        류지원,소영진 한국미용학회 2000 한국미용학회지 Vol.6 No.3

        Over their long history, the korean people have created an outstanding culture and contributed greatly to the enrichment of the treasure house of human civilization. The so-called $quot;mural tombs$quot; reveal the spirit of the Koguryo culture and are an invaluable cultural artifact. In this study, we investigated shaping form of hair style of the men and women through photographs revealed in the murals of Koguryo tumulus given by the open data. Looking at the mural, we see that the shaping form of their hair style and ornament used to shape hair are different according to the social position. The degree of variety of the men's hair style did not identified correctly because they are wearing mostly headwear and crowns whereas, in general, most of all people do their hair up into a topknot. In public space, the men wear the crowns decorated with gold or silk cloth. The hair style of the women are many various and they used turban and ornament with splendor. In order to make look as ample as possible, a false hair used to makeup hair style of the noble women. The person have low social position wears the headgear, whereas men's headgear is black and women' s white. It is observed that there is a vestige using warm hat in some areas. No matter how far back in history we go there were always some traditional technique, which were beautiful culture in character. In modern expression of the hair style, how popularization of the modified traditional shaping technique of hair style is the main topic.

      • 건조 쪽을 이용한 모발 천연염색의 표면 염색성 및 염착량

        류지원,구태규 한국인그리에학회 2021 한국인그리에학회지 Vol.3 No.1

        The purpose of this study is to determine the degree of hair dyeing according to the presence or absence of mordant use and the dyeing time using the dry indigo, the bleached hair sample was pre-mordded in alum (reagent, 5%, owh, on the weight of hair) solution for 10 minutes and then When dyeing at ℃ for 10 minutes, 20 minutes, 30 minutes, and 40 minutes, the maximum absorption wavelength of dyeing on the dry side was 420 nm. The result is as follows. First, when a mordant (Al) was used, the overall color was dyed green, and the L* value was the highest when staining for 10 minutes, followed by 20 minutes and 30 minutes. Also, both a* and b* values were found to be high in the order of 10 minutes, 20 minutes, and 30 minutes. In the case of 40-minute staining, it was the lowest. Second, when no mordant was used, all were dyed in blue green, and the L* values were high for a* and b* values in the order of 10 minutes, 20 minutes, and 30 minutes. In the case of 40-minute staining, it was the lowest. Third, in the case of K/S of the amount of dyeing, the K/S value was higher when alum mordant was not applied, and the K/S value was lower when alum mordant was applied. In both mordant and non-mordant staining, the amount of dyeing increased as the time increased for 10, 20, and 30 minutes of staining, but after 30 minutes, the dyeing was no longer combined and the dye was no longer darkly dyed. It was found that the amount of dyeing and saturation decreased as the time increased.

      • KCI등재

        근무조건에 따른 미용사의 건강상태에 관한 조사

        류지원,나영순 한국미용학회 2000 한국미용학회지 Vol.6 No.3

        The number of women who work in specified fields is growing since society has become professional and technological. Hairdressing is one of the specified fields for women hairdressers work hard standing for a long time to satisfy their customers. They get stress trying to acquire and develop new and better skills, fashion and makeup not to mention doing housework. Hairdressers use chemicals to perm and dye customers hair. These chemicals are so dangerous that they damage hairdressers skin severely and cause aching muscles and breathing problems. Hairdressers health problems were researched by using Todai Health Index(THI). Data(on the subjectire symptoms) were analyzed by one-way analysis of variance(ANOVA) Mental irritability(J) and aggressiveness(F) showed the same difference (P$lt;0.01) with working experience. Working hours were checked and the result was 39.67± 8.15 with 8 hours, 38.00 ± 8.62 with 6 hours, 37.63 ± 5.95 with 10 hours and 34.57± 7.67 with 12 hours with Respiratory(A)(P$lt;0.01). If there are more holiday the point were lower. Significance difference showed between groups like multi mental irritability(J), eyes and skin(B), digestive(C), and irregular irregular life(G)(P$lt;0.01). Significance differences in mental irritability(J) in subjective symptoms with working area were researched. The lowest point was 25.15±6.08 with people who work in housing areas and highest point was 3.11±6.90 in cities(P$lt;0.05)

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