인간수난관절편의 전기자극효과에 관하여

노효섭(HS Ro),배남규(NK Bae),변지수(JS Pyun) 대한산부인과학회 1978 Obstetrics & Gynecology Science Vol.21 No.7

1) Phamacological analysis of the effects of field stimulation of the isolated human fallopian tube has been made. 2) The electrical stimulation produced contraction of the strips, which was inhibited in the presence of tetrodotoxin. 3) The contraction induced by the electrical stimulation was not affected by hexamethonium. 4) The contraction was inhibited by atropine and regitine, but potentiated by physostigmine and cocaine. 5) It is inferred that the adrenergic neurons as well as cholinergic fibers in the human fallopian tube play important role in production of the contraction by the field stimulation.

Prostaglandin F2α 의 양막외주입에 의한 중기임신중절

김종덕(JD Kim),노효섭(HS Ro),배남규(NK Bae) 대한산부인과학회 1978 Obstetrics & Gynecology Science Vol.21 No.9

The consciously unwanted pregnancy is a complex medical-psycological-social condition. Various methods of termination at midtrimester pregnancy were individually used up to the date. It is well known that prostaglandin E and F are effective in uterine contraction in both pregnant and non-pregnant uterus. The instillation of prostaglandin F2α through Foleys catheter into extraovular uterine cavity has been shown to be effective for terminating pregnancy at midtrimester. The terminations at midtrimester were carried out by extrovular infusion of prostaglandin F2αin 22 patients between 16 and 30 gestational weeks and this method has been proved to be a safe and effective mean of terminating pregnancies at midtrimester. The results were as follows: 1. The psychological-social problems were indicated in most cases. 2. Nullipara were 12 below 25 years of age and multiparar had 2 more children, 6 cases 4 or more children. 3. The mean abortion time from initial infusion to the abortion of fetus was 25.26 hours and the mean dosage of infused prostaglandin F2α was 7.284ug. The mean abortion time and mean dosage of the prostaglandin decreased disproportionately to the increase of gestational week from 16 up to 26. 4. The initial uterine contraction was noted around 10.28 minutes and Foleys catheter was expelled between 15 and 16 hours in most cases after first infusion of prostaglandin. 5. The mean time of oxytocin augmentation after expulsion of Foleys catheter as supporting aid was 5.08 hours. 6. The most common side effects consisted of face flush, nausea, and vomiting, which disappeared spontaneously after the expulsion of Foleys catheter without specific treatment. 7. The success rate of termination in 22 patients was 95% and 3 patients were complicated by incomplete abortion.

난소에서 발생한 양성 낭성 기형종의 1예

김종덕(JD Kim),노효섭(HS Ro),최영원(YW CHOI),진소자(SJ Jin) 대한산부인과학회 1981 Obstetrics & Gynecology Science Vol.24 No.1

It was not infrequent that we have found primary malignant tumor developed in fallopian tube. But we have rarely experienced teratoma and benign cystic moreover. We have experienced one of the benign dermoid cyst primarily developed in fallopian tube and we are to report it with literary review.

가토자궁의 조직손상시 Interceed (Tc7)의 유착방지 효과에 관한 연구

김종덕,노효섭,황수경,류철희,이용미,김관식,유은영,박경배,안석문,두재근 대한산부인과학회 1993 Obstetrics & Gynecology Science Vol.36 No.10

가토자궁에 인위적 손상을 가한 뒤 복강내 첨가물질별로 수술후 유착방지 효과에 미치는 영향을 알아본 결과 다음과 같은 결론을 얻었다. 1. 복강내 첨가물질 별 조직의 유착정도는 대조군에 비해서 모든 실험군이 적게 나타났으며 이중에서 Interceed군의 유착방지 효과가 가장 우수한 것으로 나타났다. 2. 복수의 존재 유무과 유착방지 효과에 대한 연관성은 없었다. 3. 자궁에 대한 인위적 손상중 nylon봉합이 조직유착이 가장 적었다. 4. 조직구와 다핵 거대세포의 침윤, 섬유조직증식 등의 조직반응은 Interceed군이 가장 적었다. 이상과 같은 결과로 보아 고분자물질(Hyskon, SCMC 등)의 유착방지 효과는 인정되며 특히 방어막 기전으로 사용된 Interceed 군의 유착방지 효과는 우수한 것으로 사료되어 향후 산부인과 영역에서 불임이 예상되는 환자의 골반강내 수술시 Interceed의 적용은 바람직한 것으로 사료된다. 그러나 본 실험의 대상 숫자가 충분치 못하여 보다 더 정확한 결론을 얻기 위해서는 충분한 실험 동물을 대상으로 하는 연구가 필요한 것으로 사료된다. Development of adhesion reduction strategies is the topic of significant corncern to the reproductige srugeon. INTERCEED is an abosrbable fabric specially designed to reduce postoperative adhe- sion. To study the effect of INTERCEED barrier onthe formation of postoperative adhesion, 16 rabbits were randoml divided into four groups; Control group(n=4), Hyskon group(n=4), Sodium Carboxy Methy1 Cellulose(SCMC) GROUP (n=4), and INTERCEED group (n=4). All of the animals were received standardized injuries and adhesion, presence or absence of ascites and histopathologic response were compared .The results were as follows; 1. Adheions were significantly less all the experimental groups than in the control group. when the groups were compared each other according to the adjuvants and barrier, the least adhesion was noted in the INTERCEED group. 2. There was no relationship between presence or absence of ascites and effects of the adjuvants and barrier in reducing adhesion formation. 3. The least adhesion was found at the suture site with 8-0 nylon compared with other artificial injuries. 4. Tissue responsiveness assessed by infiltration of histocyte, multinucleated giant cells and fibrosis in histopathologic examination were least inthe INTERCEED group.

인공유산 시술을 받는 여성에 대한 고찰

안진섭,김종덕,노효섭,두재균,김관식,이민아,박경배,안석문 대한산부인과학회 1993 Obstetrics & Gynecology Science Vol.36 No.10

1992년 3월 1일부터 1992년 7월 31일까지 약 5개 월간에 걸쳐 인공유산시술을 받기위해 전주시내 개인산부인과의원에 내원한 여성 241명을 대상으로 사전에 준비한 구조화된 설문조사를 통하여 인공유산피시술자의 사회인구학적, 생리학적 및 의학적인 특성 법의학적인 관념, 모성건강, 차후 생식력 및 임신의 경과에 미치는 영향을 분석하여 다음과 같은 결론을 얻었다. 1. 조사대상자 연령분포는 16세에서 45세에 걸쳐 있었으며 그중 21-30세군이 69.7%로 가장 많았다. 2. 피시술자의 직업은 주부가 가장 많았고(40.2%), 그 다음이 사무직 근로자, 전문직 근로자 순이었으며 학생은 7.5%이었다. 3. 피시술자의 58.9%는 신앙이 없었으며 종교인으로는 기독교, 불교, 천주교 순으로 많았다. 4. 피시술자의 94.6%와 상대방의 95.9%가 고졸이상의 학력이었고 피시술자의 50.6%에서 양육하는 자녀가 한명도 없었다. 5. 피시술자의 72.2%가 피임하지 않은 상태이었다. 6. 피시술자의 89.2%가 반복 인공유산 시술자이었고 과거에 1회의 시술을 받은 경우가 45.2%로 가장 많았다. 7.임신임을 확인하게 된 동기는 89.7%에서 무월경과 구토증이었고 산과의사 진단은 7.5%, 자가임신진단은 0.8%이었다. 8. 임신진단을 받고난 뒤 1주이내에 인공유산 시술을 받은 경우가 77.6%이었고 2주이내가 94.2% 이었다. 9. 인공유산 시술시 최종월경일로 부터의 임신주수는 7주이내가 77.6% 8주이내가 90.8% 10주 이내가 98.3%이었다. 10. 현재 임신과 관련된 상대방과의 관계에서 볼 때 결혼이나 사실혼 상태는 58.5%이었으며 32.8%는 연애나 교제상태이었다. 11. 인공유산 시술의 동기는 가족계획(터울조절)이 38.6%, 사회적 및 법적이유가 34.0%이었으며 기타 경제적, 신체적, 의학적 이유순이었다. 12. 인공유산 시술의 결정에 있어서 87.1%가 상대방과의 상의했으며 혼자서 결정한 경우도 6.6% 를 차지했다. 13.인공유산 시술에 대한 감정에서는 $quot;그저 그렇다$quot;가 43.6%, $quot;후회한다$quot;가 32.8%,$quot;만족한다$quot;가 21.2%를 보였다. 14.법의학적으로 고찰해 볼 때 피시술자의 52.7%가 선택우선론를 지지했으며 생명우선론 18.35에 불과했다. 15. 상대방의 타인과의 혼전 성관계에 대해서는 피술자의 70.5%가 절대 반대하였지만 22.0%에서 한두번, 6.7%에서는 여러차례도 무관하다고 응답했다. The study was made of 241 women who were visited for induced abortion from March 1 st, 1992 through July 31st, 1992 to local Obstetrics and Gynecology Clinics in Chonju city. At arrival a prepared questionaire related to aociodemographic charactersitics reporoductive and medical characteristics obstetrics history of abortees motives decision affection and medico-legal view about induced abortion and result of pregnancy subsequent to the induced abortion was completed for each patient. The results were as follow: 1. In the age distirbution of acceptors, women aged 21-30 years occupied 69.7%(range 10 to 45years). 2. 40.2% of acceptors was housewife and 7.5% was student. 3. 58.9% had no religion. In religion the fist rank was Protestant(21.2% of acceptors). 4. In view of the educational elvel, 94.6% of acceptors and 95.9% of partners graduated from high school or higher. 5. 50.6% of acceptors had not a child and 72.2% of acceptors used no contraceptive methods. 6. 89.2% of acceptors was repeat aborter, and those who had had one previous induced abortion took the first rank among them(45.2%). 7. 89.7% of confirmative motives of pregnancy was amenorrhea and emesis. 8. 77,6% fo induced abortion was performed within 1 week of interval between diagnosis of pregnancy and abortion. 9. 77.65 abortion was performed within 7 weeks from LMP and 91% was within 8 weeks and 98.3% was within 10weeks. 10. Regarding to the relationship between pregnancy and partner, only 58.5% was in married state. 11. In terms of the motives of induced abortion 72.6% of abortion was due to family planning (child spacing) adn socio-legal problems. 12. Regarding to the decision-maker of induced abortion 87.1% of aborters consulted with their partners. 13. In the aspect of aborter`s emotional response, Apathy was 43.6% Regret was 32.8% and Satisfaction was 21.2%. 14 Undesirable outcomes of subsequent pregnancy, such as early abortion ectopic pregnancy, secondary infertility, uterine synechia and prematurity were reported 7.8% but did not seem to increase in such previous induced abortion group. 15. In medico-legal view for induced abortion 52.7% was pro-choice and 18.3% was pro-life.