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      • KCI등재후보

        원발성 승모판 탈출증환자에서 도플러 심초음파도를 이용한 좌심실 확장기 혈류에 관한 연구

        노인환(In Whan Ro),정진원(Jin Won Jeong),박양규(Yang Kyu Park),박옥규(Ock Kyu Park) 대한내과학회 1990 대한내과학회지 Vol.39 No.5

        N/A To evaluate the influence of primary mitral valve prolapse (MVP) associate with moderate to severe mitral regurgitation (MR) on instantaneous transmitral inflow velocities as assessed by pulsed Doppler echocardiography, this study was performed in 22 consecutive patients with MVP (14 women, 8men, mean age 38 years, range 16 to 60 years) and age-matched 22 normal subjects in whom Doppler tracings of mitral inflow velocities were recorded, Parameters of left venticular (LV) filling, including the peak rapid filling velocity (E), the peak atrial filling velocity (A), the rato of the peak rapid filling velocity to peak atrial filling velocity (E/A) and the rapid filling fraction (RFF), the atrial filling fraction (AFF), the rapid filling period (RFP) and the atrial filling period (AFP) of the patients with MVP with LV dilatation (Group 111, n=12) were compared with those of the normal subjects (Group l, n=22) and the patients with MVP without LV dilatation (Group 11, n= 10). The patients with MVP with LV dilatation have a broad range of LV inflow velocity patterns (E=1.07±0.15m/sec, A=0.60±0.13m/sec, E/A=-1,84±0.33, RFF= 74±4.8%, AFF=25±4.8%, RFP=304±72.6ms, AFP= 193±46.6 ms), as compared with the consistently long AFP (230±24.5 ms) in the MVP without LV dilatation (p<0, 01), relatively low RFF (68±4.6%, p<0,01), high AFF (31±4.6%, p<0.01) in the normal subjects. Comparing the data obtained by pulsed Doppler echocardiography, LV filling patterns in MVP associated with moderate to severe MR (with or without LV dilatation) have higher peak E and peak A than the normal patients but the MVP with I.V dilatation have shorter AFP than the MVP without LV dilatation.

      • KCI등재후보

        고혈압성 심장에서 4 심음과 좌심실 근질량 및 승모판 혈류양상의 관계

        정양호(Yang Ho Jung),김경중(Kyeong Joong Kim),허종(Jong Heo),노인환(In Whan Ro),박양규(Yang Kyu Park),정진원(Jin Won Jeong),박옥규(Ock Kyu Park) 대한내과학회 1989 대한내과학회지 Vol.37 No.6

        N/A To determine the clinical significance of the fourth heart sound (S.) in hypertensive heart, 31 patients with essential hypertension aged between 32 to 77 years old and 15 normal controls were examined by physical examination, phonocardiography and echocardiography, All hypertensive patients had normal sinus rhythm and no history of coronary artery disease nor COPD and most of them had moderate to severe hypertension. Depending upon the presence of audible S4, hypertensive patients were divided into 3 groups; those without audible S, (group I, 15 cases), those with audible S, (group II, 12 cases) and those with questionably audible S, (group III, 4 cases). M-mode echocardiograms of the left ventricle and pulsed wave Doppler echocardiograms of the mitral valve were performed to determine the left ventricular thickness/dimension ratio (T/D), left ventricular mass index (LVMI) and A/E ratio of mitral flow pattern. T/D and LVMI were significantly increased in both hypertensive group I and group 11 (p<0.01) and T/D of hypertensive group II was more increased than that of hypertensive group I (p<0,05), but there was no significant difference between hypertensive group I and group II in LVMI. In contrast, the A/E ratio of mitral Doppler flow pattern was increased only in hypertensive group II compared to normal controls (p<0.01), and there was a significant difference between hypertensive group I and group II (p<0.01). Audible S, was found in hypertensive patients with an A/E ratio greater than 1.10 and in a normal person with an A/E ratio of 1.27, and all 10 hypertensive patients above an A/E ratio of 1.20 except one had an audible fourth heart sound. In conclusion, audible fourth heart sound is a useful bedside parameter for detecting left ventricular diastolic dysfunction in the hypertensive heart.

      • KCI등재후보

        이리 및 인접 지역에서 발생한 쭈쭈가무시병 40 예에 대한 임상적 고찰

        유웅선(Woong Sun Yu),노인환(In Whan Ro),허종(Jeong Huh),김경중(Kyeong Joong Kim),안태규(Tae Gyoo Ahn),이용구(Yong Goo Lee) 대한내과학회 1989 대한내과학회지 Vol.37 No.4

        N/A We reviewed 20cases of tsutsugamushi disease who were admitted to WonKwang University Hospital from October to November 1988 and the following clinical results were obtained: 1) Seasonally, the 40cases mainly occurred from Odctober to November. 2) Most of the cases resided in rural areas or were associated with farm work and the age distribution was mainly in the forties. fifties, and sixties. The number of female cases was twice that of male cases. 3) On physical examination, rash, lymphadenopathy and eschar were observed in 38 cases (95%), 28cases (70%) and 17cases (42.5%) respectively. 4) On laboratory findings, leukocytosis (15%) and leukopenia (10%) were observed but anemia was not observed. The degree of elevation of AST and ALT was 2 or 3 times the normal values and elevation of LDH was observed in all cases. 5) On EKG, sinus tachycardia was observed in 6cases (15%). On simple chest X-ray, abnormal X-ray findings (20%) were observed. 6) One case was positive to Weil-Felix reaction. Indirect immunofluorescent antibody test was performed in 26cases of which 3cases (84.6%) were positive. Thirteen cases were positive to indirect immunofluorescent antibody test among 14cases with eschar. 7) Thirty-nine cases were treated with T-C and doxycycline and one case was treated with chloramphenicol. Thirty-eight cases recovered, one case died 3 days after early discharge and the clinical course of one case was not known after early discharge.

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