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Gultamate 및 Kainate에 의하여 유발된 흰쥐척수후각세포 반응에 미치는 칼슘의 효과
김찬,신홍기,안현정,강석한 한양대학교 의과대학 1998 한양의대 학술지 Vol.18 No.1
Excitatory amino acids have been known to play an important role in the transmission of nociceptive signals in the spinal cord. The present study was undertaken to examine the effects of changes in calcium ion concentration on the responses of spinal dorsal horn neurons to EAAs. At first, the responses of LT (low threshould) and WDR (wide dynamic range) cells to iontophoretically applied glutamate and kainate were recorded before and during iontophoretic application of Ca^2+, Mn^2+ and EGTA. And the changes in spontaneous activity of the WDR cells were observed following iontophoretic application of Ca^2+, Mn^2+, EGTA and verapamil. Also studied was the effect of prolonged spinal application of EGTA on the glutamate - induced responses of the WDR cells. The spontaneous activity of WDR cells was strongly inhibited by iontophoretically applied Ca^2+, Mn^2+, and verapamil but greatly augmented by EGTA. The iontophoretically applied kainate produced excitation of all the LT and WDR cells whereas glutamate evoked excitation of all WDR cells and approximately 50% of LT cells. The responses of LT and WDR cells to glutamate and kainate were dose-dependently suppressed by Mn^2+ and Ca^2+ + but augmented by iontophoretically applied EGTA. The EGTA - augmented responses were reduced by Ca^2+ and Mn^2+. However, the response of WDR cell to glutamate was suppressed after a prolonged (15-20min) spinal application of EGTA. These experimental findings suggest that in the spinal cord, excitatory amino acids excite LT as well as WDR cells and that the transmission of EAA-induced sensory singals is modulated by the changes in calcium ion concentration.
유리면에 코팅된 저 굴절률 Teflon-AF 박막에 의한 투과율 증가효과 측정
김찬,이일수,김도형,박상철,박종구,배홍섭,유경재,이형락 한국물리학회 2007 새물리 Vol.55 No.5
We report an enhancement of the light transmittance through glass with a Teflon-AF film. Compared with a bare glass sample, we observed about a 20 \% increase in light transmittance for the glass with a Teflon-AF film. When light propagates from the glass to air, total reflection occurs. The Teflon-AF film greatly reduced this total reflection and, thus, increased the light transmittance. 저 굴절률 Teflon-AF 막을 입힌 유리 시료의 투과율을 측정하여 유리의투과율과 비교함으로써 저 굴절률 막에 의한 투과율 상승효과를측정하였다. 각도에 따른 투과율의 변화를 stepping motor와 GPIB 인터페이스를 이용하여 컴퓨터에 의해 자동으로 제어하면서 반복실험을통해 정확한 투과율을 측정할 수 있었다. Teflon-AF 막이 입혀진 유리와막을 입히지 않은 유리(bare glass)에서의 투과율을 비교하면중앙부분에서는 약 20 \%, 전체적으로는 약 15 \%의 차이가 나는 것을관찰할 수 있었다. 이러한 실험결과는 Teflon-AF막을 평판 디스플레이구조에서 ITO와 유리사이에 끼워 넣음으로써 디스플레이의 out-coupling 효율을 개선하리라고 기대된다.
측두하악관절에서 발생한 건활막 거대세포종 - 증례보고 -
김찬,장석정,Kim, Chan,Jang, Suk Jung 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.10
A rare case of tenosynovial giant cell tumor of invading left temporomandibular joint(TMJ) extending the middle cranial fossa is reported. Report of this entity in the temporomandibular joint is rare. A 39-year old male patient presented with mild discomfort and swelling in preauricular area. MR image demonstrated a destructive lesion of the left TMJ, with bony erosion of temporal bone and extension into middle cranial fossa. The patient underwent radiotherapy as adjuvant therapy to prevent recurrence, followed by resection. The histological and radiological features of this tumor are discussed along with a brief description of the disease entity.
협부형 척추전방전위증에 대한 후방가동관절 이용한 골유합술 및 척추경나사못 고정술의 수술적 결과
김찬,이승명,신호,Kim, Chan,Lee, Seung Myung,Shin, Ho 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.1
Objective : Posterior lumbar interbody fusion(PLIF) provides the favorable outcome to degenerative lumbar disease, especially isthmic spondylolisthesis. To determine the long-term effect of PLIF using psterior movable segment, we analysed the results of follow-up radiologic changes and surgical outcome retrospectively Patients and Method : During the past 11 years(1989. 1.-1999. 9.), 148 patients with symptomatic lumbar spondylolisthesis were managed at our department and the clinical wants were throughly recieved and final outcome is determined at last follow up. PLIF using antogenous bone(posterior movable segment, iliac bone and rib) were performed in 106 case. Results : After an average follow-up period of 33 months(range ; 15-58 months), the results were excellent in 66 cases, good in 37 cases, fair in 2 cases and poor in 1 cases. And the satisfactory results were 103 cases(98.2%) in PLIF,. Conclusion : In conclusion, patients who underwent PLIF with autologous bone graft had good clinical and radiological outcomes without significant neurological complications.
스프레이 열분해 방법으로 제작한 Cu2ZnSnS4 박막의 공기 중 열처리 효과
김찬,이일수,홍성욱 한국물리학회 2015 새물리 Vol.65 No.2
Cu2ZnSnS4 (CZTS) 박막을 스프레이 열분해 코팅방법으로 제작하였다. 스프레이 코팅을 위한 CZTS 용액은 2-methoxyethanol과 ethanolamine의 혼합 용액에 염화구리 (CuCl2), 염화아연 (ZnCl2), 염화주석 (SnCl2), Thiourea (CH4N2S) 분말을 넣은 후 초음파로 분산시켜 제조하였다. 이 CZTS용액을 유리 기판에 고르게 분사한 후 공기 중에서 300, 400, 500 ℃ 의 온도에서 각각 1, 2, 3분간 열처리하여 CZTS 박막을 형성하였다. X-선 회절 분석 결과 500 ℃ 의 온도에서 1분간 열처리한 박막의 결정성과 결정립의 크기가 가장 우수하였으며, 이는 주사현미경으로 확인한 결정 알갱이의 크기 결과와 잘 일치하였다. 또한 이 박막은 홀 효과 측정으로 28.98 × 1017 cm−3 의 전하 운반자 농도를 가지는 p-형 반도체임을 확인 하였다. Cu2ZnSnS4 (CZTS) thin films were fabricated by using spray pyrolysis deposition. CZTS ink was prepared from CuCl2, ZnCl2, SnCl2, and thiourea (CH4N2S) powders that were dispersed in a mixed solution of 2-methoxyethanol and ethanolamine by using a sonochemical method. The films were fabricated by heat-treating the specimen in air and uniformly spraying CZTS ink on the glass. Heat treatment was performed at several different temperatures (300, 400, 500 ℃) and different durations (1, 2, 3 min). The best crystallinity and crystal size of the CZTS thin films were obtained at a temperature of 500 ℃ for a 1-min treatment, according to X-ray diffraction measurement results. These results agree well with the data provided by the images of scanning electron microscopy. Furthermore, Hall-effect measurements on the sample confirmed that it was a p-type semiconductor and that its carrier concentration was 28.98 × 1017 cm−3.