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뇨세포검사로 진단된 방광의 배아성 횡문근육종 - 1 증례 보고 -
김주헌,이호,강명재,이동근,김상호,Kim, Joo-Heon,Lee, Ho,Kang, Myoung-Jae,Lee, Dong-Geun,Kim, Sang-Ho 대한세포병리학회 1994 대한세포병리학회지 Vol.5 No.1
Rhabdomyosarcomas are found mainly in young patients, but rare in adults. A correlated cytological and histologic study of one case of embryonal rhabdomyosarcoma is presented. The cytologic appearance of the urine smear corresponded well with the histologic findings. Cytologically, two main cell types were distinguished ; a predominant primitive, small round cell with scant cytoplasm and a large cell with abundant cytoplasm. The cytologic feature proving rhabdomyoblastic differentiation, such as cross-striation, was absent.
한국내 일본계 외국인투자기업의 경영행태- 비 일본계 외투기업과의 비교분석 -
김주헌,설원식 한일경상학회 2008 韓日經商論集 Vol.39 No.-
Thisstudyempirically compared management behaviors of Japanese subsidiaries in Korea with those of subsidiaries from other countries using mail survey data.Japanese subsidiaries showed a general tendencytowardlocalizationinvariousaspects.First,they source(ratio of locally sourced input) and produce(ratio of locally produced sales) more locally than other foreign subsidiaries in the Koreanmarket.Theyalsoshowedalower(higher)levelof standardization(local adaptation) in marketing strategies. Between the bipolar points of 'sticks to general Korean practices' and 'sticks to Headquarters' practices' regarding management practices in Korea, Japanese subsidiaries are closer to the former, while the other subsidiaries are closer to the latter.Similar patterns also appear in the decision making location, which means Japanese subsidiaries tend to make decisions more locally at the subsidiary level. All these findings were reconfirmed in the regression analyses controlling for the equity ratio, which implies that higher localization level of Japanese subsidiaries is not just a result of their lower equity ratios.
미성숙 돼지 자궁 평활근의 운동성에 대한 Adenosine Triphosphate와 Prostaglandin $F_{2{\alpha}}$ 작용의 관계
김주헌,권종국,김용근,Kim, Joo-Heon,Kwun, Jong-Kuk,Kim, Yong-Keun 대한생리학회 1988 대한생리학회지 Vol.22 No.1
This study was carried out to investigate the action of adenosine triphosphate (ATP) on the motility of immature pig uterine smooth muscle. ATP appeared contractile responses in a dose-dependent manner, showing the maximal contraction at the concentration of $10^{-3}M$ in the uterine smooth muscle strip. The contractile responses by $ATP(10^{-4}M)$ were not affected by atropine $(10^{-6}M)$, phentolamine $(10^{-6}M)$, propranolol $(10^{-6}M)$, pyrilamine $(10^{-6}M)$, cimetidine $(10^{-6}M)$, and theophyulline $(5{\times}10^{-5}M)$, but were inhibited uncompetitively by quinidine. The effects of these drugs on the contractile responses by prostaglandin $F_{2{\alpha}}(PGF_{2{\alpha}})$ were also comparable to those observed with ATP. When muscle strips were pretreated with indomethacin $(5{\times}10^{-5}M)$ for 20 min., the contractile responses by $ATP(10^{-4}M)$ were completely inhibited. But the contractile responses by $PGF_{2{\alpha}}$ were not affected by indomethacin. These results suggest that ATP elicited the contraction through noncholinergic- and nonadrenergic-receptor mediated by prostaglandin $F_{2{\alpha}}$ in pig uterine smooth muscle.
우리나라 벤처기업의 수출마케팅 전략 및 성과에 대한 실증적 연구
김주헌 한국국제경영관리학회 2006 국제경영리뷰 Vol.10 No.1
본 연구에서는 우리나라 수출 벤처기업을 대상으로 수출마케팅전략 및 수출성과에 영향을 미치는 요인들에 대해 가설을 설정하고 이들 가설을 우편설문 자료를 통해 실증적으로 검증하였다. 실증분석 결과 우리나라 벤처기업의 수출마케팅전략 및 수출성과에는 수출에 대한 최고경영자의 적극성이 매우 중요한 역할을 하는 것으로 나타나고 있다. 수출성과에는 최고경영자의 적극성 외에도 기업의 국제경험과 외부기관과의 네트워크 활용 정도 등이 유의한 영향을 미치는 것으로 분석되었다. 그러나 가설과 달리 제품과 촉진활동의 적응화는 어느 것도 수출성과에 유의한 영향을 미치지 않는 것으로 나타났다. 이는 벤처기업의 경우 제품 및 촉진활동에 현지 시장상황을 반영하여 부분적인 수정을 거치는 현지 적응화보다는 기업 및 최고경영자라는 기업의 중심적 특성이 수출성과에 더 중요한 요인임을 시사하는 것이다. 즉, 외형적 수출마케팅전략의 선택보다 국제경험의 축적, 최고경영자의 수출에 대한 적극적 관심과 태도가 수출성과 증진에 우선적으로 요구된다는 것을 의미한다. This study empirically investigated the relationships among internal and external factors, export marketing strategies, and performance of Korean venture companies. The results showed that CEOs' attitudes had an important effect on strategy formulation and performance of export marketing. Firm's international experience and external networks were also found to have positive effects on export performance. Neither product nor promotion adaptation, however, was found to have a significant effect on export performance. This implies that export performance of venture companies is affected by characteristics of a firm itself rather than marketing mix strategies adapted to local market conditions. In other words, venture companies need to accumulate international experience, and their CEOs need to have positive attitudes toward export to enhance performance.
고등급 림프종으로 형질전환된 원발성 림프절 변연부 B-세포 림프종 -1예 보고-
김주헌,박미자,김진만,강동욱 대한병리학회 2003 Journal of Pathology and Translational Medicine Vol.37 No.4
Primary nodal marginal zone B-cell lymphoma (MZBCL) is recognized as a rare and distinct entity. The rate of histologic transformation into diffuse large B-cell lymphoma (DLBCL) seems lower than the rate of transformation in follicular lymphoma. We herein report a rare case of nodal MZBCL showing transformation into DLBCL. The patient was a 73-year-old female with cervical lymphadenopathy. On the initial biopsy, the lymph node architecture was diffusely effaced with an extensive interfollicular and parafollicular infiltrate of monocytoid B-cells. There were scattered large blastic B-cells without formations of compact sheets. The diagnosis of nodal MZBCL was made. The patient did not receive chemotherapy and was treated with a conservatively supportive regimen. Forty two months later, the patient developed a new cervical lymphadenopathy and a biopsy was performed. Histologically, the lymph node revealed diffuse sheets of transformed large B-cells showing prominent nucleoli. The diagnosis of DLBCL transformed from nodal MZBCL was made. The patient was treated with 3 cycles of combined CHOP chemotherapy and she showed clinical improvement. These observations suggest that an untreated primary nodal MZBCL may undergo high-grade transformation.
제1형 신경섬유종증과 동반된 다발성 위장관 간질종양- 2예 보고 -
김주헌,김성호,강동욱,김경희,박미자,김용일,성인옥,이성규,백행운 대한병리학회 2006 Journal of Pathology and Translational Medicine Vol.40 No.2
Gastrointestinal stromal tumor (GIST) is the most common non-epithelial neoplasm arising in the gastrointestinal tract, but this tumor is rarely seen in association with type 1 neurofibromatosis (NF-1). We report here on two cases of multiple GISTs of the small intestine that occurred in NF-1 patients. We also analyzed the mutations of c-kit exons 9, 11, 13 and 17 and the plateletderived growth factor receptor-alpha (PDGFRA) exons 12 and 18 in two GIST patients. Histologically, the NF-1-associated GISTs were similar to those of non-the NF-1 GISTs, but they characteristically revealed hyperplastic interstitial cells of Cajal around the GISTs. Immunohistochemically, these tumors showed strong co-expressions of CD117 and CD34. The molecular genetic analysis of the GISTs showed that all of the c-kit and PDGFRA exons that were analyzed in the GISTs of the two patients were the wild-type, suggesting a limited role for the c-kit and PDGFRA mutations in the tumorigenesis of NF-1-associated GISTs.