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      • Study of metal cation selectivity by alkyl chain length between 1,2,3- triazole and spiropyran

        김인원,이민혜,사디시쿠마르,이주현,송창식 한국공업화학회 2016 한국공업화학회 연구논문 초록집 Vol.2016 No.0

        Spiropyran (SP) is an important class of photochromic molecule. Under UV light irradiation, the closed form of SP can be converted into the open merocyanine (MC) form through spiro cleavage and the MC form can retain to their original SP form under visible light irradiation. In this study, we design and synthesize triazole linked spiropyran compounds by click reaction. In this opportunity, we present the synthesis of two metal binding site SP and 1,2,3-triazole linked through different length of alkyl chain. The reversible interconversion between the SP and MC form can attain by metal cations without any external stimuli. According to this phenomenon, SP is able to utilize as metal cations sensor. We find that different alkyl chain length between SP and 1,2,3-triazole can effect on selectivity of our metal sensor system.

      • KCI등재

        주산기 저산소증에 의한 뇌손상의 MR 소견

        김인원 대한영상의학회 1992 대한영상의학회지 Vol.28 No.2

        MR imaging of the brain in 34 patients were reviewed to characterize the MR findings of brain damage due to perinatal hypoxic insult All the patients had a history of perinatal hypoxia and showed abnormal brain MR findings. Out of 34, eight infants were born promature and twenty-six were born at term or post-term. MR findings were analysed for the extent and location of abnormalities of the white matter. cortical abnormality. corpus callosum atrophy, and abnormal progression of myelination. The major abnormalities were abnormal signal lesions or atrophy of the cerebral white matter and gyral atrophy of the cerebral cortex. The distribution of white matter lesions well correlated with maturity of the brain at the time of hypoxic insult. Periventricular and deep white matter lesions predominated in the premature-born patients. Corpus callosum atrophy was frequently seen. reflecting the location of white matter injury. Delay in myelination was present in 55%. MR is a very useful iagnostic imaging modality and guide for the prediction of prognosis by accurate depiction of the location and extent of brain damage due to perinatal hypoxic insult.

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        Bioactive compounds and antioxidant activities of sprout soybean fermented with Irpex lacteus mycelia

        김인원,이혜빈,심상협,양은인,김용석 한국식품과학회 2017 Food Science and Biotechnology Vol.26 No.6

        To enhance the biological activities of sprout soybean, beans were treated with steaming (SS), germinating (GS), or roasting (RS) prior to fermentation with Irpex lacteus mycelia for 20 days. The total phenolic, flavonoid, isoflavone, and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity of each fermented bean preparation were examined every 5 days for 20 days. The total phenolic content of SS, GS, and RS preparations was 9.61, 10.23, and 10.46 mg/g, respectively, after 15 days of fermentation. These concentrations were approximately 4–5 folds higher compared to initial levels. The total flavonoid content was 8–9 folds higher than initial levels. The isoflavone content was highest in the RS sample (6.84 mg/ g). The DPPH radical scavenging activity of beans fermented with I. lacteus mycelia was increased 2–8 folds after 20 days of fermentation. These results indicate that antioxidant activity components were increased by fermentation of I. lacteus mycelia irrespective of soybean treatments.

      • KCI등재
      • KCI등재

        방사선 폐염에 대한 실험적 연구

        김인원,최병인,김주완 대한영상의학회 1981 대한영상의학회지 Vol.17 No.2

        The study was undertaken to evaluate the radiological and microscopic findings of radiation penumonitis. All 50 rats, which used for the experiment, received a single dose of 2,000 rads of radiation on right lung using 60 Co teletherapy. Chest teleroentgenograms were checked weekly for 13 weeks and microscopic examinations of irradiated lung were performed monthly after irradiation. The results obtained are summerized as follows. 1. In roentgenologic examination, radiation pneumonitis began to appear 4 weeks after irradiation and progressed with time intervals and began to resolve after 11 weeks. 2. Chest roentgenologic findings were pneumonic consolidation, atelectasis, and pleural effusion of irradiated right lung with compensatory hyper-inflation of left lung. 3. In the microscopic examination, pneumonitis appeared 2 weeks after irradiation and progressed with time intervals and began resolve after 8 weeks. 4. The microscopic findings were fibrin deposit in alveoli and in reased septal cellularity, vascular thickening , edema and congestion. After septal fibrosis and hyperplasia of bronchial mucosa, suggesting early regenerative change of radiation fibrosis, were noted 12 weeks after irradiation.

      • KCI등재

        내시경적 역행성 담.췌관조영술 소견에 관한 고찰

        김인원 대한영상의학회 1979 대한영상의학회지 Vol.15 No.2

        Advances in fiberoptic duodenoscopy permit direct observation of interior of the duodenum and cannulation of the ampulla of Vater, and to perform endoscopic retrograde cholangiopancreatography. Authors analized the 30 cases of E.R.C.P. done at the Department of Radiology, Seoul National University Hospital between Feb. and Aug. 1979, which were compared with the final diagnosis. The results are as follows; 1. Out of 30 cases, successful visualization of the duct of concern was achieved in 23 cases. 2. Out of 10 cases of suspected pancreatic disease, pancreatic duct was visualized in 7 cases, and 5 cases revealed pathognomonic findings. All 5 cases were diagnosed as pancreatic cancer and their findings were encasement, local dilatation, poor filling and obstruction of pancreatic duct accompanying C.B.D. obstruction or stenosis, so called double dubt sign. 3. Out of 19 cases of suspected biliary tract disease, biliary tract was visualized in 16 cases and 14 cases revealed sugges ive abnormal findings. In biliary stones, filling defect with proximal dilatation and obstruction were noted. 4. Post-E.R.C.P. complications were vague abdominal pain, asymptomatic hyperamyasemia, elevated amylase clearance ratio and symptoms due to premedication or post-E.R.C.P. antibiotics therapy. Elevated serum amylase concentration or clearance ratio were within normal range and it dose not seem to have clinical significance.

      • 소아의 구토에 대한 방사선학적 진단

        김인원,Kim, In-Won 한국건강관리협회 2003 한국건강관리협회지 Vol.1 No.1

        Vomiting in pediatric patient is frequently encountered problem in emergency room or outpatient clinic. In differential diagnosis, age of the patient or accompanying symptoms should be considered in the differential diagnosis. Accurate diagnosis is very important because surgical treatment is necessary in some of the conditions. Imaging diagnosis of conservative modality such as upper gastrointestinal series or colon study is still important radiological examination in the initial differential diagnosis, but recently ultrasonography offers accurate diagnosis in many situations. The cause of vomiting in pediatric are diverse according to the age group :neonatal sepsis, necrotizing enterocolitis, or hypertrophic pyloric stenosis in neonates : gastroesophageal reflux, viral enteritis, or intussusception in infant: midgut volvulus, appendicitis, metabolic disorders, or increased intracranial pressure also an be the cause. knowledge of radiological findings of normal gastrointestinal tract is important to recognize abnormalities. A discussion of radiological findings in variable surgical conditions to present as vomiting in pediatric patients is offered.

      • 도서관과 교육계획

        김인원,Kim, In-Won 한국도서관협회 1971 圖協月報 Vol.12 No.7

        이 글은 불란서 파리에 있는 국제교육계획연구소가 매년 주관하는 교육계획가 훈련과정에 포함된 도서관계획 세미나에서 토의된 내용과 계획업무 및 수행방법 등을 검토한 글을 번역한 것이다. 역자 주

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