급성임파성 백혈병을 동반한 피부근염 1 예

김도원,정상립,서기석 대한피부과학회 1982 大韓皮膚科學會誌 Vol.20 No.1

Dermatomyositis is a disease mainly of the skin, muscle and blood vessels in which erythematous and edematous changes in the skin are associated with muscle weakneas and inflammation. In adult the disease is commonly associated with underlying malignancy or reticulosis. A 23 year-old male had generalized weakness, intermittent fever, myalgia and purplish red patches on the face. Diagnosis of dermatomyositis was established by clinical manifestations, electromyogram, histologic findings of skin and muscle. He was treated with systemic steroid, with some improvement. Seven months after the onset of dermatomyositis, ecchymoses was noted on the eyelids and forearms. Bone marrow aspiration showed many immature lymphoblasts, characteristic of acute lymphocytic leukemia, He was treated with systemic steroid and vincristine, but no favorable effect was noted. He died of sepsis due to retal abscess on the 34th day in the hospital.

대상포진 환자에서의 급성 동통 및 포진후 신경통에 대한 임상적 고찰

김도원,권순백,정상립,이석종 대한피부과학회 2000 대한피부과학회지 Vol.38 No.3

Background:Pain in the form of acute neuritis and postherpetic neuralgia is by far the most frequent and most debilitating complication of herpes zoster. The pain of acute herpes zoster may be severe, but it is usually transitory. Some patients, with the elderly at particular risk, go on to develop postherpetic neuralgia. Postherpetic neuralgia is often severe and, unfortunately, refractory to most forms of treatment. Objective:The purpose of this study was to compare the severity of acute pain and incidence of postherpetic neuralgia by age group, dermatomal distribution and the presence and absence of associated diseases. Methods:We observed the severity of initial pain, changes in severity of pain during treatment, and the incidence of postherpetic neuralgia in 105 patients with herpes zoster with the same therapeutic measures (systemic steroid, acyclovir, analgesics, and tricyclic antidepressant). And we compared them by age group (the young & middle age vs the old age group), dermatomal distribution(trigeminal, cervical, thoracic, and lumbosacral), and the the presence and absence of associated diseases respectively. And we also analyzed the relationship between the incidence of postherpetic neuralgia and the severity of initial pain. Results: 1. Sixty-six patients (63%) of the total number of subjects complained of initial `severe pain', and the incidence of initial `severe pain' was significantly higher in the old age group (78%) compared with the young & middle age group (48%). But, there was no significant difference by dermatomal distribution and the presence and absence of associated diseases. 2. The duration of pain was 2-4 weeks in 27 patients (26%), 1-2weeks in 26 (25%), more than 8 weeks(postherpetic neuralgia) in 24 (23%). 3. The mean comparative value of the severity of pain was 38% of initial pain after 3 days of treatment, 22% 1 week, 15% 2 weeks, 8% 4 weeks, and 5% 8 weeks, respectively. But, there was no significant difference in changes of severity of pain by age group, dermatomal distribution, and the presence and absence of associated diseases. 4. The incidence of postherpetic neuralgia was significantly higher in the old age group (35%) compared with the young & middle age group (11%). But there was no significant difference by dermatomal distribution and presence and absence of associated disease. And the incidence of postherpetic neuralgia was also significantly higher in the initial 'severe' pain group (33.3%) than in the initial 'mild' pain group (14.3%) and the `moderate' pain group (3.1%). Conclusions:Older patients with herpes zoster showed severer initial pain and a higher incidence of postherpetic neuralgia. But there was no significant difference in the severity of initial pain and incidence of postherpetic neuralgia by dermatomal distribution and the presence and absence of associated diseases. And patients with initial severe pain showed a higher incidence of postherpetic neuralgia than those with mild and moderate pain, respectively.

백모에 관한 통계적 및 임상적 관찰

김도원,신동주,김정철,정상립,이석종 대한피부과학회 1999 대한피부과학회지 Vol.37 No.11

Background:Graying of hair is usually a manifestation of the aging process and is due to a progressive reduction of the activity of melanocytes in the hair bulb. Objective:We performed this study to investigate the clinical features of the graying process in Koreans. Method:The study population consisted of 1,058, comprising 589 men and 469 women between the fourth and seventh decade. They were studied statistically by using questionaires about graying and 12 persons with gray hair were observed clinically on the grouping pattern of scalp hairs by the dermatologist. Result: 1. More than 50 percent of the population over 40 years old had gray hair on the scalp. 2. The age of onset of graying was variable but generally between 35 and 44 years. 3. The temporal area of the scalp was the most common site of initial graying and the most abundant site of gray hair. 4. There were no relationship between gray hair and male pattern baldness. 5. Generally each one of the hairs in the grouped hair became gray independently, not in union. 6. The proportion of graying in the grouped hair was higher than that of the single hair. Conclusion:According to the results of the study, more than 50 percent of the population over 40 years of age have gray hair and the temporal area usually becomes gray first and is the most abundant site of gray hair. Further studies will be needed in regard to the graying in the grouped hair, though we think that each one of the hairs in the grouped hair may become gray independently and the graying process of the grouped hair may occur earlier than that of the single hair.

명예훼손죄 비범죄화에 대한 논의와 <자유론>의 입장 ― 존 스튜어트 밀 <자유론>을 중심으로 ―

김도원 연세대학교 법학연구원 공공거버넌스와 법센터 2020 연세 공공거버넌스와 법 Vol.11 No.2

현행 형법상 제307조가 규정하는 명예훼손죄, 그중에서 제1항의 ‘사실적시 명예훼손죄’를 비범죄화하자는 논의가 활발하다. 이와 같은 명예훼손 비범죄화 논의의 찬반 양측 모두 각자의 근거로 밀의 <자유론>을 들고 있다는 점에서 본 논문 작성이 시작되었다. 과연 존 스튜어트 밀 본인은 명예훼손죄 비범죄화에 대하여 어떠한 입장을 가졌을 지 본 논문은 그의 저서인 <자유론>을 통해서 그의 진정한 입장을 추론해보고자 하였다. 밀의 <자유론>에 따르면 국가기관이 개입할 수 있는 근거는 결국 정당한 토론의 조건이 되는 법적 분쟁의 ‘균형’을 만들어주는 것이다. 사회적, 경제적 강자와 약자의 불균형은 우리 사회가 수인하고 받아들여야 하는 문제이지만, 적어도 사법의 영역에서 무엇이 정의이고 진리인지 논의하고 토론할 때는 양 당사자 간의 균형이 요구되어야 한다. 이에 따라 명예훼손죄와 관련된 사안에서 형법 제307조 제1항의 사실적시 명예훼손죄 중, 사인의 공인에 대한 사실적시에 의한 명예훼손은 형사처벌을 배제하는 것이 바람직하다는 결론에 이르렀다.

초록집 : 피부 장벽기능의 검사

김도원 대한피부과학회 1996 초록집 Vol.- No.-

Optimal energy mix under climate risk

김도원,류희랑,이지웅,김경국 한국시뮬레이션학회 2017 한국시뮬레이션학회 학술대회집 Vol.2017 No.-

AES 계면활성제 흡착에 따른 CaCO₃ 표면 특성 변화에 관한 연구

김도원,송은민,김민규,손종석,임종주 한국공업화학회 2014 한국공업화학회 연구논문 초록집 Vol.2014 No.1

본 연구의 목표는 음이온 계면활성제가 나노 CaCO₃ 표면에 흡착하여 그 표면 특성이 변하는 메커니즘을 이해하고, 궁극적으로 CaCO₃ 표면을 소수화하여 윤활유 첨가제로써 활용성을 높이는 것이다. 실험에 사용한 음이온 계면활성제는 AES (alcohol ethyoxy sulfate)와 각각을 칼슘, 마그네슘으로 중화한 계면활성제이다. 제타 전위 측정을 통해 등전점 이하의 pH에서 CaCO₃ 표면이 양전하를 띄는 것을 알 수 있었고, 따라서 양전하인 CaCO₃ 표면에 음전하를 띄는 음이온 계면활성제 head group이 정전기적 인력으로 흡착하게 되는 메커니즘을 확인하였다. CaCO₃를 음이온 계면활성제에 반응시켜 표면 개질한 후 FT-IR(Fourier transform infrared spectrometry)을 측정한 결과 음이온 계면활성제 피크가 나타났다. 또한 농도별 계면활성제 수용액을 이용하여 표면 소수화 된 CaCO₃ 위에 물을 떨어뜨려 접촉각을 측정하여, 계면활성제 농도가 증가하면 표면 소수성이 점점 커지다가 일정 농도 이상부터는 다시 작아지는 결과를 얻었다. Floating Test 실험에서도 접촉각 실험과 동일한 경향의 Active Ratio 결과를 얻었다. 또한 QCM-D (Quartz crystal microbalance) 측정으로 음이온 계면활성제의 농도가 커질수록 단위 면적당 계면활성제 분자의 흡착량, 흡착두께가 모두 증가하는 것을 확인 하였다.

Polydiacetyelene Embedded Porous Silicon Photonic Crystals for Nerve Agent Vapors Remote Sensing

김도원,이지석 한국고분자학회 2022 한국고분자학회 학술대회 연구논문 초록집 Vol.47 No.2

별 볼 일 있는 인생

김도원 (사)방송기자연합회 2022 방송기자 Vol.66 No.-

Study on adsoprtion of fluorinated surfactant on CaCO₃ surface

김도원,임종주,손종석,이수민,이주연,조서연,김은별 한국공업화학회 2015 한국공업화학회 연구논문 초록집 Vol.2015 No.1

본 연구의 목표는 불소계 계면활성제가 탄산칼슘 파우더 표면에 흡착하여 표면 특성이 변화하는 것을 증명하는 것이다. 실험에 사용한 계면활성제는 Dupont사의 Zonyl TBS로, 음이온 계면활성제로서 등전점 이하에서 양전하를 띠는 탄산칼슘 표면에 흡착하였다. 불소계 계면활성제를 표면에 흡착시킨 탄산칼슘 분말의 FT-IR(Fourier transform infrared spectrometry) 측정결과 탄소-불소 peak이 나타났고, XRF(X-ray fluorescence)를 통해 계면활성제의 농도가 증가할수록 불소 함량이 증가하는 것을 확인 하였다. 접촉각과 Active Ratio가 일정 농도까지 증가하다가 감소하는 것을 통해 탄산칼슘 표면에 이중층을 형성하여 소수성이 감소함을 확인하였다. 또한 개질시킨 탄산칼슘 분말의 Surface Energy가 증가하였다가 감소하는 것을 확인하였다.