흰쥐 해마에서 Norepinephrine 유리에 미치는 Protein Kinase C 의 영향

김도경,이영수,최봉규,Kim, Do-Kyung,Lee, Young-Soo,Choi, Bong-Kyu 대한약리학회 1995 대한약리학잡지 Vol.31 No.2

The effects and interactions of $4{\beta}-phorbol$ 12,13-dibutyrate(PDB) and polymyxin B(PMB) with adenosine on the electrically-evoked norepinephrine (NE) release were studied in the rat hippocampus. Slices from the rat hippocampus were equilibrated with $^3H-noradrenaline$ and the release of the labelled product, $^3H-NE$, which evoked by electrical stimulation$(3\;Hz,\;2\;ms,\;5\;VCm^{-1},\;rectangular\;pulses)$ was measured. PDB$(0.3{\sim}10\;{\mu}M)$, a selective protein kinase C(PKC) activator, increased the evoked NE release in a dose related fashion while increasing the basal rate of release. And the effects of $1\;{\mu}M$ PDB were significantly inhibited by $0.3\;{\mu}M$ tetrodotoxin(TTX) pretreatment or $Ca^{++}-free$ medium. $PMB(0.03{\sim}1\;mg)$, a specific PKC inhibitor, decreased the NE release in a dose dependent manner while increasing the basal rate of release. Adenosine $(1{\sim}10\;{\mu}M)$ decreased the NE release without changing the basal rate of release, and this effect was significantly inhibited by 8-cyclopentyl-1,3-dipropylxanthine$(2\;{\mu}M)$, a selective $A_1-receptor$ antagonist, treatment. Also, adenosine effects were significantly inhibited by PDB-and PMB-pretreatment. These results suggest that the PKC plays a role in the NE release in the rat hippocampus and might be participated in a post-receptor mechanism of the $A_1-adenosine$ receptor.

SHS화학로에 의한 SiC의 합성

김도경,박성,조건,이형복,Kim, Do-Kyung,Park, Sung,Cho, Kurn,Lee, Hyung-Bock 한국세라믹학회 1994 한국세라믹학회지 Vol.31 No.11

Ultra-fine $\beta$-SiC powders were fabricated by self-propagating high temperature synthesis process (SHS) using chemical furnace. The dependences of the C powders with different surface areas, the molar ratios of C/Si, the weight ratios of chemical fuel content, and pellet diameter-size on synthesis were investigated. Compositional and structural characterization of these powders was carried out by scanning electron micrograph and X-ray diffraction. The $\beta$-SiC powders which had C/Si mole ratio=1.05, 3 times chemical fuel contents, and pellet diameter=20 mm were optimum for synthesis efficiency. By optimizing process-variables, it is possible to fabricate $\beta$-SiC powders which have little secondary phases ($\alpha$-SiC).

SHS법에 의한 Ti-Si계 세라믹스의 합성 및 소결체의 특성에 관한 연구

김도경,박성,조덕호,조건,이형복,Kim, Do-Kyung,Park, Sung,Cho, Duk-Ho,Cho, Kurn,Lee, Hyung-Bock 한국세라믹학회 1994 한국세라믹학회지 Vol.31 No.3

Intermetallic Ti-Si system ceramics were synthesized from stochiometric mixtures of titanium and silicone powders in vacuum by Self-propagating High-temperature Synthesis(SHS). In each cases of Ti5Si3, Ti5Si4 and TiSi, and TiSi2 synthesis, 20wt% product dilution, direct ignition and SHS chemical furnace method were employed. The combustion modes, which were observed during the synthesis process by using the high speed camera, of Ti5Si3, Ti5Si4, TiSi, and TiSi2 exhibit spin, osciallatory, steady-state, and spin combustion, respectively. With increasing Ti/Si molar ratio an decrease of combustion velocities was found. From the results on the measurement of the flexural strength, the specimen hot pressed at 135$0^{\circ}C$ for 30 min using synthesized Ti5Si4 powders showed the highest flexural strength at 215 MPa.

아급성 육아종성 갑상샘염의 세침흡인 세포소견 -아급성 육아종성 갑상샘염 10예의 임상-세포소견 및 면역세포염색 소견 분석-

김도경,표주연,박종필,김연화,정우희,손은주,홍순원,Kim, Do-Kyung,Pyo, Ju-Yeon,Park, Jong-Pil,Jin, Lian-Hua,Jeong, Woo-Hee,Son, Eun-Ju,Hong, Soon-Won The Korean Society for Cytopathology 2008 대한세포병리학회지 Vol.19 No.1

Although subacute granulomatous thyroiditis(SGT) is usually diagnosed clinically, papillary carcinoma or other thyroid conditions must be considered in the differential diagnosis. We retrospectively reviewed the clinical and fine-needle aspiration(FNA) cytologic findings seen in 10 SGT cases to decide what are the most reliable cytologic findings and the most helpful molecular tools for reaching a confident cytologic diagnosis. The most representative smear slides were retrieved to perform immunocytochemistry for cytokeratin 19(CK19) and Ret protein. Five papillary carcinomas(PTCs) were included as controls. The constant and typical cytologic findings of SGT were multinucleated giant cells(MGCs) (100%), epithelioid granulomas(90%), an inflammatory dirty background(90%) and plump transformed follicular cells(80%) without fire-flare cells, oncocytic cells or transformed lymphocytes. The immunoreactivities for CK19(37.5%) and Ret(10%) of the follicular cells of SGT were less than those(CK19 and Ret:100%) of PTC. CK19 immunoreactivity of the MGCs was seen in only one case of PTC. There was no significant difference between CK19 and Ret immunocytochemical staining for the MGCs of both SGT and PTC. The results of this study demonstrate that the cytological diagnosis of SGT can be improved by employing a combination of the typical and constant diagnostic cytological features and immunocytochemical results.

중장년층 성인의 종교에 따른 노후준비도에 관한 연구

김도경(Kim, Do Kyung),김윤신(Kim, Yoon Shin),송기민(Song, Ki Min) 한양대학교 고령사회연구원 2013 한양고령사회논집 Vol.4 No.1

본 연구의 목적은 서울ㆍ경기 수도권에 거주하는 중장년층 성인의 종교에 따른 노후준비 정도를 파악하는데 있다. 2013년 4월 22일~5월 5일 사이에 서울ㆍ경기 수도권지역을 중심으로 만30세~64세 중장년기 성인 총 300명이 응답한 설문지 자료를 SPSS WIN 18.0으로 분석하였다. 주요연구결과를 요약하면 다음과 같다. 첫째, 대상자의 인구사회학적 특성에서 남성이 164명(54.7%)으로 여성(45.3%)보다 많았고, 연령에서는 30대 119명(39.7%)으로 가장 높게 나타났다. 또한 대상자의 종교유형에 따라서는 무교가 125명(41.7%)으로 가장 높게 나타났고, 1주 종교활동 시간에 따라서는 없음 186명(62.0%)으로 가장 높게 나타났다. 둘째, 대상자의 종교유형에 따른 노후준비 정도를 분석한 결과, 통계적으로 유의미한 차이를 보이지 않았지만, 1주 종교활동 시간에 따른 노후준비도는 유의미한 차이가 있는 것으로 나타났다. 특히, 1주 4시간 미만의 종교활동은 경제적, 신체적, 정서적 노후준비도가 가장 높은 것으로 나타나 적당한 종교활동은 노후준비에 긍정적인 영향을 미치는 것으로 보인다. Recently, the improvement of standard of living and the development of medical technology have extended the average life expectancy in our country, which resulted in the aging society with increased numbers of the aged population. This increase of the aged population is changing the viewpoint about the old age from the life extension to the healthy aged life, and to more attention to the quality of life. (Sin mee Kim, Sun yee Kim, 2009). This research collected the questionnaires polled three hundreds of the middle aged people and seniors who are living in Seoul and Gyeonggi-do metropolitan area. The followings are the brief outcome of the research. The research reveals the preparation level for the declining life in accordance with sociological characteristics of the population varies as per the age, weekly religious activity, marriage status, the type of family, monthly average income, subjective financial status, and subjective health condition. This research may have the limits, one may be the regional limit because the sampling method of the research objectives was restricted to Seoul and a part of Kyeong Gi Do metropolitan area, and the other may be the error of generalization because only the aged people and seniors were collected for questionnaires. The aim of the study was to discover the relation between the religion and prepare for their old age. especially, the variables of religion is the religious type and religious activity time in a week In this study, Christianity, Buddhism, Catholicism, such as old age religions according to the type of preparation showed no significant differences. However, It is found to have a significant difference between the religious activitiesone in a week and prepare for their old age.

MMO RPG 게임에서 캐릭터와 던젼과의 크기에 대한 상호관계의 연구

김도경(Do-Kyung Kim) 한국컴퓨터정보학회 2009 韓國컴퓨터情報學會論文誌 Vol.14 No.11

본 논문은 MMORPG 게임에서 캐릭터 대비 통로의 적절한 크기를 유추하고 이를 기존 게임에 대비하여 역 산출함으로써 데이터의 객관성을 높임과 동시에 통로의 기능에 따라 다양하게 표현되고 있는 실내 내부의 크기에 관한 연구이다. 이 연구를 위하여 데이터를 객관화 시키는 작업부터 하였으며, 던전이라는 특성화 된 기능을 지니는 통로의 규정을 이동을 위한 목적 및 소규모로 진행되는 전투 기능까지의 범위로 한정시켜 실험을 진행하였다. 그리고 게임의 장르에 따른 게임그래픽의 종류를 MMORPG로 한정시켜 실험의 결과 값을 정형화하였으며 캐릭터의 크기의 객관성을 위해 실사풍의 RPG 게임으로 한정시키고 그래픽디자이너의 성향에 따라 크기의 차이를 얼굴의 크기에 맞추어 신체크기 값을 통일 시켰다. 캐릭터의 크기 중 어깨넓이, 팔 길이 등 이동성 던젼의 넓이의 특징 점으로 찾았으며, 이를 분석하여 MMORPG 게임의 메인캐릭터의 상체의 크기를 이용하여 이동성 던젼의 크기를 재구성 하여 4개의 실험데이터를 게임전문가 200명에게 적절한 게임 던젼의 크기를 선택하도록 인지 실험을 하였다. 이에 캐릭터와 이동성 던젼의 비례관계를 감성적인지 관점에서 허용범위의 평균값을 얻을 수 있는 산출 공식을 만들 수 있었다. This paper is focusing on the optimal size of internal space in which various functions are expressed by means of analogizing appropriate size of passage fitted to characters and reverse-calculating it in comparison with preexisting games, and thus increase the objectivity of data. To this end, the work of making the data objective was conducted in advance, and the experiment proceeded in the way that specially-designed Dungeon can make its way through the passage and in the situation where small-scale combats take place. In addition, the efforts were made to standardize the outcome of experiments by restricting the types of game graphics to MMO RPG. Further, the enhance the objectivity of size of the characters, the game types were limited to RPG games, and it is also adjusted to the character's face size based on the graphic designer's preference. The size of shoulders and arms of characters, inter alia, was selected as distinguishing points to be adjusted to the passage. By analyzing these data, the size of passage was re-organized according to the main characters in the MMO RPG games. Four experimental data was utilized by the 200 game experts in order to select the optimal size of passage in the game. As a consequence, the proportional correlation between character and passage movement was evaluated as successful in terms of emotional recognition.

전방십자인대 재 재건술 후 슬관절 근력의 비교: 전방십자인대 최초 재건술과의 비교

김도경 ( Do Kyung Kim ),박원하 ( Won Hah Park ) 대한스포츠의학회 2016 대한스포츠의학회지 Vol.34 No.1

The purpose of this study was to assess the knee strength and anterior laxity in between primary and revision anterior cruciate ligament (ACL) reconstruction. It was a cross-sectional study; 28 patients who had undergone revision ACL reconstruction and the another 30 patients who had primary ACL reconstruction once were compared each other which they all had been operated during the same period of season with the same technique in the same hospital. The isokinetic equipment was used to measure the main outcome for knee strength, and KT-2000 arthrometer was used for measuring anterior drawer test in 12 months post-reconstruction surgery. In the anterior drawer test, we found out that there were significantly differences between primary and revision ACL reconstruction groups (1.5±1.1 mm vs. 2.6±1.5 mm, p=0.001). There was no significant difference in the deficits of knee extensor and flexor muscle strength between primary and revision ACL reconstruction. Revision reconstruction groups have more laxity in anterior drawer than primary reconstruction groups. After revision ACL, the deficits of knee extensor and knee flexor muscle strength have no significantly difference from primary ACL reconstruction.

포항 R&BD기관의 집적과 지역에 대한 영향

김도경(Do-Kyung Kim) 대한지리학회 2023 대한지리학회 학술대회논문집 Vol.2023 No.06

마인추(馬寅初) 비판과 상징을 통한 지식 통제

김도경 ( Do Kyung Kim ) 현대중국학회 2013 現代中國硏究 Vol.14 No.2

이 이 글은 마인추(馬寅初)가 어떻게 사회적 상징이 될 수 있었고, 그리고 어떻게 그 상징이 인구 조절 논의를 장시간 억제할 수 있었는지를 설명한다. 1950년대 그에 대한 비판은 두 차례 있었는데, 이것은 그가 어떠한 방해도 없이 자신의 의견을 제시할 수 있었다는 사실과 밀접하게 관련되어 있다. 중국 공산당이 마인추의 글을 허용하였던 것은 그의 인구 조절론을 보급하기 위했던 것이 아니라, 그의 지식이 얼마나 잘못되었는지를 보여주기 위한 것이었다. 일단 마인추가 거짓 인구론의 상징이 되자, 중국 사회에는 ``금지된 영역(禁區)``이 형성되었고, 마인추라는 상징을 통해 중국 사회는 무엇이 사회주의 인구론인지를 알 수 있었다. 인구 조절론이 장시간 ``금지된 영역``으로 남을 수 있었다는 사실은 중국 공산당이 지식의 관리와 통제에서 물질적이고 강압적인 방법만을 사용한 것이 아니라, 상징을 통해 문화적 구조를 만드는 방식도 사용하였음을 알려준다. This article describes how Ma-Yinchu(馬寅初) has been a symbol, and how the symbol could suppress the discourses of population control. In the 1950s, he was criticized twice, and it was mainly involved with the fact that he was able to post his opinion without interruption. The Communist Party allowed Ma-Yinchu to publish his papers in order not to disseminate his knowledge of population control, but to show how false his knowledge was. Once Ma-Yinchu was a symbol of untruth, ``forbidden area(禁區)`` was created in China. The symbol of Ma-Yinchu showed what is socialist knowledge of population control to Chinese citizens, and this is called as symbolic way of controlling knowledge by the author. The Communist Party not only controlled the material conditions of knowledge production and knowledge circulation, but also invented a symbolic way of controlling knowledge, and this made the discourse of population discourse a ``forbidden area`` for a long time.

지역 이미지의 상징성 표현을 위한 가로환경시설물 디자인 개발 연구

김도경(Kim Do-kyung),임창빈(Im Chang-bin) 한국디자인학회 2003 디자인학연구 Vol.16 No.1