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建康韓國人의 肺容積, 最大換氣量 및 秒時肺活量에 對하여
金大洙,李聖行,朴熙明 慶北大學校 醫科大學 1959 慶北醫大誌 Vol.2 No.1
1. The normal values of the total lung capacity and its subdivisions in 56 young Korean males and 13 females are presented. Methods used in the current study consist in the analysis of the graphic record of ventilatory movements by Krogh's respirometer and the measurement of the functional residual capacity by the Lundsgaard and van Slyke method modified by one of us (T. S. K). 2. In the male subjects, the ratio of each lung volume to the total lung capactity, the correlation between the body size and lung volumes, and the interrelation of each lung volume are determined. A comparison of our results to those of Europeans and Americans is made. 3. The maximal breathing capacity and the timed vital capacity were measured in 96 healthy Korean males and 16 females by the use of Korgh's respirometer made suitable by one of us (T. S. K. ) for these measurement. The interrelation of the maximal breathing capacity to the body size and the vital capacity in male subjects is described. 4. The advantages and disadvanatges of the various methods for the determination of functional residual capacity are briefly discussed and the easy practical applicability and the theoretical validity of our modification of the Lundsgaard and Van Slyke original method are presented.
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單一呼氣分析에 依한 混合靜脈血液 및 動脈血液의 炭酸 GAS 張力의 測定法 및 深博出量 測定에의 應用에 關하여
金大洙 慶北大學校 醫科大學 1963 慶北醫大誌 Vol.4 No.1
This method is based upon the O_2 and CO_2 analysis of several gas samples collected successively during a single expiration of 7-10 seconds. During this period the CO_2 rises and the exchange ratio(R) falls rapidly. Theory:(1) A decrease in blood CO_2 content, with no change in O_2 content (R=∞) lowers the PCO_2. An increase in O_2 content, with no change in CO_2 content (R=O) increase the PCO_2. When R is equal to O.32, PCO_2 remains constant. (2) During expiration the alveolar PCO_2 increases, reducing the CO_2 output while the O_2 uptakes remains unaffected. Thus R is directly related to CO_2 exchange, which in turn is governed by the venous-alveolar CO_2 tension difference. As long as the mixed venous PCO_2 remains unaltered, there must be a linear relationship between alveolar PCO_2 and R, provided the arterial O_2 content remains essentially constant. Application: In each of the gas samples, PCO_2 and PO_2 and R are determined. When R is plotted versus PCO_2, a straight line is obtained as predicted. The true mixed venous PCO_2 can be read at an R value of O.32, the arterial-alveolar PCO_2 at the appropriate R, and the "oxygenated venous blood" PCO_2 at an R of O. Cardiac output determined by this method at rest and moderate exercise agree with those obtained by blood analysis methods.
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兪昌濬,金大洙 慶北大學校 1962 論文集 Vol.6 No.-
The physical natures, especially volume-pressure curves of the excised rabbit lung have been studied in number of experiments to see the mode of changes produced by the temperature and the velocity of air injected into the lung. Also an analytical observation was made on the specificity of the curves, and the results obtained are summarized as follows. (1) Pressure elevation following the injected of certain amount of air into the lung is proportionate to the speed of the air injection. The intratracheal pressure after the ceasation of the air injection decreased exponentially with time and the pressure difference between initial and equilibrium pressure was proportionate to the speed injection and the total amount of air injected. (2) The equilibrium pressure was observed unchanged with the speed throughout the entire experiments, bearing no particular relation with speed of the air injection. (3) The volume-pressure curve at the time of the air injection showed a parabola, its compliance being in proportion to the volume. (4) The volume-pressure curve in hypothermia state did not differ much from that of room temperature. However, its compliance was generally sell than nomal. (5) When the lung was kept under the condition of cooling and expansion for prolonged period of time, say over 12 hours, the volume-pressure curve of the equilibrium pressure showed nearly straight line, indicating increase of compliance and decrease of hysteresis. (6) The volume-pressure curve when the lung volume was diminished following the expansion, showed a parabola, its compliance being decreased at the beginning and increased at the end of the shrinking, A similar pattern was obtanined under different experimental conditions. (7) The volume-pressure curve, when the air was alternately injected into and ejected from the exciced lung showed a closed loop curve. Such a phenomenon of hysteresis could be explainde by the hypothetical basis that the lung is composed of the groups of alveoli having the different critical opening pressure.
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개구리(Rana nigromaculata)의 呼吸에 關하여
金圭秀,金大洙 경북대학교 의학연구소 1966 慶北醫大誌 Vol.7 No.1
This study was aimed to obtain more detailed knowledges concerning the gas exchange through the lung and the skin in frogs. The O_2 consumption and CO_2 elimination through both the lung and the skin were determined separately. The change in gas exchange through the lung after blocking the skin respiration by immersing the frog into liquid paraffin or in water was observed. The blood was sampled from the ventricles of frogs to determine the gas contents, gas tension and pH. The composition changes in gases in the peritoneal and subcutaneous gas pockets were observed to estimate the tissue gas tension. The results obtained are as follows: 1. The normal expired volume of frogs. of mean body weight 29 grams, is 0.42 ㎖/min(ATPS) and the inspired volume 0.43㎖/min(ATPS). The O_2 and CO_2 concentration in the expired gas are 11.07% and 2.07% respectively, and the O_2 uptake and CO_2 elimination are calculated as 7.65 ㎖/hr/100g B.W. (STPD) and 1.55 ㎖/hr/100g B.W. (STPD) respectively and the gas exchange ratio of the lung is 0.2. 2. The O_2 uptake and CO_2 elimination through the skin are 23.4 ㎖/hr/100g B.W. (STPD) and 36.85 ㎖/hr/100g B.W. (STPD) respectively, and the gas exchange ratio of the skin is 1.57. The over-all O_2 uptake and CO_2 elimination are calculated as 31.05 ㎖/hr/100g B.W. (STPD) and 38.40 ㎖/hr/100g B.W. (STPD) respectively, and the over-all gas exchange ratio is 1.2. 3. The O_2 uptake from the lung are increased up to 191% and CO_2 elimination up to 338% when the skin respiration was blocked by liquid paraffin; and the corresponding increase of O_2 uptake and CO_2 elimination are 112% and 269% respectively when the frog was submerged into water completely. 4. The O_2 and CO_2 contents of ventricular blood of frogs are 3.4 vol% and 36.3 vol% respectively, and O_2 capacity of the blood is 8.72 vol% and the pH is 7.44. The P_CO2 and P_O2 of the blood are 16.3㎜Hg and 64㎜Hg respectively. These show that the frog's blood is more alkaline and has lower bicarbonate concentration than those of mammals. 5. The compositions of gases in the subcutaneous and intraperitoneal gas pockets show that they are approaching toward the gas tension of the blood itself. 6. The main function of frog's lung in general presumably is to regulate the increased need of gas exchange during enhanced muscular activity and/or increased environmental temperature, and the decreased gas exchange thrgouh the skin during swimming in water.
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右心 CATHETERIZATION에 隨伴되는 不整脈에 對하여
金萬在,朴熙明,吳相鎭,金大洙,李聖行 慶北大學校 1960 論文集 Vol.4 No.-
Few reports are available on arrhythmias occurring during right heart catheterization despite mechanism disorders are the most important complication of the procedure from the view point of its frequency and seriousness. The purpose of the present study is to investigate the incidence and varieties of arrhythmias occurring in association with thirty-three right heart catheterizations performed on thirty-one patients with congenital and acquired heart diseases. The nature and frequency of the arrhythmias are as follows; Premature atrial contraction 75% Paroxysmal atrial tachycardia 13% Atriaf fibrillation 3% Premature nodal contraction 9% Premature ventricular contraction 87% Paroxysmal ventricular tachycardia 16% Heart block(Grade I, Ⅱ, Ⅲ) 16% Intraventricular conduction disturbance 6%
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