Beta₂-agonist의 장기적, 규칙적 사용에 따른 부작용

권정혜,고영률 中央醫學社 1996 中央醫學 Vol.61 No.2

근거기반실무로서 난임상담의 실제

권정혜 한국여성심리학회 2019 한국심리학회지 여성 Vol.24 No.2

Given the high percentage of women who experience mental health problems and the great demand for infertility counseling, there is an urgent need to develop infertility counseling as evidence-based practice in Korea in near future. The purpose of this study was to review the current status of infertility counseling as evidence-based practice and provide suggestions and policy directions for infertility counseling in Korea. First, psychological distress and mental health status of infertile women or couples were briefly reviewed. Second, the purposes and content of infertility counseling were presented. Third, the empirical evidence of the efficacy of infertility counseling was reviewed. Forth, the requirements and training of infertility counselors in countries where infertility counseling has been integrated as a necessary component of infertility treatment such as UK, Germany, and Australia were reviewed. We need to develop cost-effective infertility counseling to meet the needs of Korean women and couples and monitor outcomes of the counseling which will be used as evidence and utilized to improve the efficacy of infertility counseling.

선진국에서의 정신보건법 현황 및 시사점

권정혜 한국임상심리학회 1995 정신보건법에 관한 임상심리학회 토론회 Vol.- No.-

사회행동 배열과제의 개발과 타당도 연구: 정신분열병 환자의 사회인지 능력을 측정하는가?

권정혜,전진수,최기홍 한국임상심리학회 2003 Korean Journal of Clinical Psychology Vol.22 No.3

The purpose of this study was to develop the Social Behavior Sequencing Task (SBST) measuring social-cognitive ability of schizophrenics and examine its reliability and validity. The Social Behavior Sequencing Task was developed following the format of the Schema component sequencing task used by Corrigan, Wallas, & Green(1992). The final six items of the Social Behavior Sequencing Task were selected based on the results of the preliminary study in which 10 items were administered to 200 college students. To establish the reliability and validity, the Social Behavior Sequencing Task was then administered to 42 schizophrenics attending the community rehabilitation centers and 46 normal adults. Results demonstrated that the Cronbach alpha coefficient was .87 indicating high reliability. It was also shown that there was a significant difference between the schizophrenic group and the normal group on the mean of the SBST, t(86)=-3.40. p < .01. The results of the correlational analyses indicated that the score of the SBST was significantly correlated with the score of the picture arrangement subtest of KEDI-WISC, r=.47, p < .01 but not with the vocabulary subtest of K-WAIS, r=.14, ns. The SBST was also found to be significantly correlated with two measures of social skills(r=.44 & -.58), demonstrating high validity. Implications of the results were discussed along with its limitations.

우울증 환자의 역기능적 대인관계 특성

권정혜 한국임상심리학회 2002 Korean Journal of Clinical Psychology Vol.21 No.3

The purpose of this study was to examine if insecure attachment served as interpersonal vulnerability of depression and if insecure attachment affected marital functioning of depressed patients. Participants were 31 female outpatients with depression (depression group) and 32 normal women(control group). They were assessed on the measure of depression, subjective marital satisfaction, marital relationships, attachment style and general dysfunctional attitude. Specifically, interview technique was used to evaluate marital relationship and attachment style. Results indicated that insecure attachment style was significantly more prevalent in the depression group than in the control group. Among aspects of insecure attachment, depressed patients showed a higher level of the desire for engagement and anger in relationships than women in the control group. Subjective marital satisfaction, confiding in husband, quality of positive interaction with husband and security characteristics of marriage were lower in the depression group than in the control group, and the quality of negative interaction with husband was higher in the depression group than in the control group. Achievement-oriented and dependency-oriented dysfunctional attitude were higher among depressed patients than among women in the control group. Within the depression group, patients with secure attachment and those with insecure attachment group were compared. There was a significant difference in the subjective marital relationship between two groups, and active emotional support by husband tended to be lower in the insecure attachment group than in the secure attachment group. Achievement-oriented dysfunctional attitude tended to be higher among patients with insecure attachment group than those with secure attachment. Implications and limitations of this study were discussed.

진행성 비소세포폐암에서 Cisplatin과 Etoposide가 포함된 3제 복합항암화학요법의 결과

권정혜,신종욱,김재열,정형원,박인원,최병휘,이상재,손동섭,허성호 중앙대학교 의과대학 의과학연구소 2001 中央醫大誌 Vol.26 No.3

Purpose:Treatment of non-small cell lung cancer(NSCLC)have made modest prolongation of survial and improvement in quality of life. Although many studies have tried to treat the non-small cell lung cancer with combination chemotherapy based on cisplatin and etoposide, it remains to be certain what kind of assitional drugs and schedules can be applied. Thus, we conducted this study to assess the therapeutic effects of three different chemotheraeputic regimens, all containing cisplatin and etoposide, in patients with advanced NSCLC. Materias and Methoods: Eighty patients were enrolled who had histologically confirmed NSCLC with advanced stage, normal renal and bone marrow function. Sixteen patients were treated with FVP(cisplatin 20 mg/㎟ i.v. days 1∼5, etoposide 60mg/㎡ i.v. days 1∼5, 5-fluorouracil 800mg/㎟ i.v. days 1∼5), 36 patients with CVP(cisplatin 60mg/㎡ i.v. day 1, etoposide 80g/㎡ i.v. days 1∼5, cyclophosphamide 1000mg/㎡ i.v. day 1), and 28 patients with VIP(cisplatin 20mg/㎟ i.v. days 1∼5, etoposide 60mg/㎡ i.v. days 1∼5, ifosfamide1000mg/㎡ i.v. day 1∼5). Each cycle was repected every 3 or 4 weeks. We evaluated response rates, duration of remission, survival time, treatment-related toxicity and prognostic factors for survival. Results: One patient treated with VIP showed complete respose. Response rate of FVP(37.5%) and VIP(39.3%) were significantly higher than that of CVP(16.7%)(p=0.04). Median duration of remission was not significantly different among three groups(FVP14.9, CVP5.8, VIP7.3 months). No significant difference was found in overall median survival time among three groups(16.0 momths in FVP,14.3in CVP,17.3 in VIPgroup). In respoders to each therapeutic regimen, median survival times of FVP(21.5 months),VIP(undefined were significantly prolonged than 9.3 months of CVP group(p=0.016). We found that divided administration of cisplatin had relieved severe nausea and vomiting. Finally, as a result of prognostic factor analysis with Coxs proportional hazard model, chemotherapy was found to be significant prognostic factor for survival benefit in advanced NSCLC. Conciusion: Higher response rate and significant prolongation of survival time had been acquired as results of addition of ifosfamide or 5-fluorouracil to cisplatin and etoposide-based chemotherapy. In accordance with these data,it is warranted to conduct further prospective randomized study with combination of cisplatin, etoposide, ifosfamide and 5-fluorouracil.

정신분열병 환자를 위한 사회인지 재활프로그램의 효과:Ⅰ. 1차 연구

권정혜,고영 한국임상심리학회 2002 Korean Journal of Clinical Psychology Vol.21 No.2

The purpose of this study was to evaluate the effectiveness of the social-cognition enhancing rehabilitation program developed by Kwon(2000). The main components of the program were helping schizophrenic patients perceive social situations accurately, understand the interpersonal implications of given social situations, and express nonverbal and verbal behaviors which are socially appropriate. Four clinical trials were performed to evaluate the impact of social-cognition enhancing rehabilitation program on schizophrenic patients' social perception and social skills. For the first, second, third and fourth administration, participants were five, eight, six, and six chronic schizophrenic patients, respectively, who were attending community-based rehabilitation center. They attended ten weekly 60-min-sessions of social-cognition enhancing rehabilitation program. Control group of 20 patients who were institutionalized chronic schizophrenia was compared to the third and fourth treatment group. Both group were administered and rated on the picture arragemenet subtest of KEDI-WISC, Social skills inventory, Interpersonal functioning Inventory, and Social perception test before and after the program. Results of covariance analysis indicated that the social-cognition enhancing rehabilitation program was effective in increasing social skills, but not in enhancing social cognition. The implications of the results were discussed.

난임 심리 상담

권정혜 한국모자보건학회 2017 한국모자보건학회 학술대회 연제집 Vol.2017 No.2

事例硏究에 대한 方法論的 考察

권정혜 서울대학교 의과대학 정신과학교실 1982 精神醫學報 Vol.6 No.7

Beta₂ - agonist의 장기적 , 규칙적 사용에 따른 부작용

권정혜,고영률 대한천식알레르기학회 1995 천식 및 알레르기 Vol.15 No.3