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LCD Backlight용 CCFL 보호 회로에 관한 연구
장유진(Yujin Jang),구본암(Bonahm Gu),공정철(Jungchul Gong),공승곤(Seungkon Kong),신상철(Sangchul Shin),민병운(Byoungown Min) 전력전자학회 2007 전력전자학술대회 논문집 Vol.- No.-
본 논문에서는 램프가 한개 이상 개방 시 피드백 제어 회로를 동작하지 않도록 하면서, 램프를 보호할 수 있는 개방전압을 출력하는 LCD 백라이트 구동용 인버터 회로도에 관한 것이다. 램프 개방전압 출력을 위한 회로는 램프 전류 피드백 블록, 개방전압시 이상신호를 감지하는 전압 피드백 블록, 램프 개수에 상관없이 최고치 값을 감지하는 블록으로 되어 있다. 전술한 회로가 내장된 인버터는 램프의 개방 시 램프의 개수 상관없이 CCFL의 보호 스펙인 2500V의 개방전압을 출력한다. 이러한 인버터가 내장된 LCD패널은 향상된 안정화 동작을 구현하게 된다.
카바프로스타싸이클린의 중간체로 이용가능한 히드록시싸이클로펜탄의 합성
서영거(Young Ger Suh),구본암(Bon Am Koo),정재경(Jae Kyung Jung),조윤상(Young Sang Cho),나운용(Woon Lyong Lah) 대한약학회 1993 약학회지 Vol.37 No.3
An efficient synthetic route to the trisubstituted cyclopentane as an useful synthetic intrermediate for carbaprostacyclin is described. Ireland Claisen rearrangement of a hydroxylactone has been employed as a key reaction.
Macrolide의 새로운 합성 -8-Membered Lactone의 합성-
서영거(Young Ger Suh),구본암(Bon Am Koo),조윤상(Youn Sang Cho) 대한약학회 1990 약학회지 Vol.34 No.3
An efficient synthetic route to macrolide is described. Eight-membered lactone was synthesized via palladium catalyzed intramolecular alkylation of allylic carbonate in high yield.
김예진,허웅,최한석,강기성,황귀서,백지윤,구본암,김현영 한국생약학회 2019 생약학회지 Vol.50 No.3
Periodontitis is a chronic inflammatory disease and gums pull away from the teeth and form spaces. The main goal of treatment is to control the infection and anti-inflammation. Eucommia ulmoides Oliv. Bark (EU) is a traditional Korean herbal used for the treatment of arthritis and hypertension. In the present study, we investigated the anti-inflammatory properties of EU in Porphyromonas gingivalis-LPS (LPS-PG) induced YD-38 epithelial cells. We observed significant inhibition of nitric oxide (NO) production and the expression of interleukin-8 (IL-8), interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-a), cyclooxygenase-2 (COX-2) in LPS-PG-induced YD-38 cells. These results support that EU has an anti-inflammatory effects for the treatment of periodontitis.
카바프로스타싸이클린 중간체의 합성: 1-Alkoxy-benzenesulfonyl-cyano-4-ethenyl cyclopeptane의 입체선택적 합성
서영거(Young Ger Suh),정재경(Jae Kyoung Jung),구본암(Bon Am Koo),최영기(Young Gi Choi),조윤상(Youn Sang Cho) 대한약학회 1995 약학회지 Vol.39 No.1
An efficient and stereoselective synthetic route to the trisubstituted hydroxy cyclopentane as an useful synthetic intermediate for carbaprostacyclin is described. Pd(O)-mediated intramolecular alkylation of allylic carbonate has been employed as a key reaction.
Inhibitory Effects of KM1701 on Airway Cell Infiltration in OVA-Induced Mouse Model
임순민,최한석,김상백,김예진,강기성,신명숙,김경준,황귀서,구본암 대한한방안이비인후피부과학회 2019 한방안이비인후피부과학회지 Vol.32 No.2
Objectives : The objective of present study is to evaluate anti-inflammatory and anti-allergic effects of Perilla(Perilla frutescens; Labiatae, PF), the roots of Peucedanum praeruptorum(PP) and the root of Scutellaria baicalensis(SB) in vitro and anti-asthmatic effects of mixture of PF, PP and SB(PS) on ovalbumin (OVA)-induced asthma in BALB/c mice. Methods : Anti-inflammatory and anti-allergic effects were observed on the lipopolysaccharide(LPS) treated RAW 264.7 cells through Nitric Oxide(NO) production and RBL-2H3 cells through β-hexosaminidase. Anti-asthmatic effects were observed on the number of inflammatory cells in bronchoalveolar lavage fluid(BALF) and the level of IgE in serum on OVA-induced BALB/c mice. Results : The treatment of PF, PP and SB(12.5, 25, 50, 100㎍/㎖) resulted in a significant inhibition of NO production in RAW 264.7 cells and mast cell degranulation in RBL-2H3 cells. Oral administration of PS(400㎎/㎏/day) resulted in a significant reduction in the numbers of eosinophils in BALF and level of IgE in serum. Conclusion : The oral administration of PS is effective in ameliorating the eosinophilic infiltration in vivo and thus can be a good therapeutic candidate for allergic asthma.