자화 관련 탐구 활동

강현정 한국초등과학교육학회 2015 한국초등과학교육학회 학술대회 Vol.68 No.-

자석은 학생들이 일상생활 속에서 많이 경험하는 소재이다. 따라서 익숙하고 잘 알고 있는 내용이라고 여기기 쉬우나 실제 학생들에게서는 자석과 관련된 오개념이 자주 발견된다. 특히 ‘자화’ 개념에 대해서 학생들의 오개념이 두드러지게 나타나는데, 이는 자기력이 실제 눈으로 확인할 수 없는 것이기 때문이다. 따라서 효과적으로 자화 개념을 학습시키기 위해서는 학생들에게 자기력을 시각적으로 구체화하여 제공하는 것이 좋다. 본 워크숍에서는 자화와 관련하여 다양한 실험을 통해 자화에 대해 깊이 이해하고, 실제 수업에 적용 할 수 있는 방안도 함께 논의 해 보고자 한다.

Integrity in Promise Keeping

강현정 한국윤리학회 2020 倫理硏究 Vol.130 No.1

Most people agree that it is morally wrong to break a promise. There are, however, many different views on why it is wrong and whether it is because a promisor undertakes a promissory obligation. One dominant view is that you undertake an obligation when you make a promise. For instance, Joseph Raz seems to agree that the general reason why you have to keep your promises is because you undertake obligations by the speech act. On the other hand, some people think that it is not an obligation that matters. Thomas Pink thinks that a promisor and a promisee do not need to care about what obligation a promisor undertakes, because what matters to them is the promised action itself rather than the specifically promissory obligation. I suggest that when people make a promise they in general have in mind what sorts of obstacles they are willing to overcome in order to keep a promise. When one fails to overcome the set bar of the obstacles, he undermines his integrity by also failing to be a consistent person. There are amounts of obstacles that you are willing to overcome when you make a promise. When you fail to overcome ‘the bar of obstacles that you set when you made a promise’, because you are undermining your integrity, you are to be blamed for breaking a promise.

Imaging Features of Madelung’s Disease: Case Report

강현정,이인숙,차원재,김학진,송유선,고진영 대한자기공명의과학회 2015 Investigative Magnetic Resonance Imaging Vol.19 No.2

Madelung’s disease, or benign symmetric lipomatosis, is an uncommon disorder thatis characterized by massive symmetrical deposits of adipose tissue in the upper trunk,neck and head, and is usually associated with alcohol abuse; as such, patients usuallycomplain of cosmetic issues. Historically, Madelung’s disease is usually encounteredin men between 30 and 60 years of age, and is more prevalent in the Mediterraneanpopulation. In this case study, we describe a rare case of Madelung’s disease, in anAsian patient who presented with symmetrically located bilateral masses in theanterior neck, which grew progressively larger over a period of seven years.

[가족여행] 친정어머니의 친정 나들이

강현정 샘터사 2012 월간 샘터 Vol.507 No.-

자유로운 선택에 대한 이해 가능성

강현정 범한철학회 2020 汎韓哲學 Vol.97 No.2

One of the interesting arguments in the recent debate of free will is J. Fischer’s narrative account. According to him, free will is valuable in the sense that it allows us to shape the narrative structure of our lives. Narrative accounts offer ‘loops’ for the agent by allowing him to redirect his life. J.M. Boyle et al., on the other hand, have suggested free will as a possibility of the third-person perspective account of an individual’s life. According to them, a person’s actions and activities are explained by his basic commitments and these basic commitments must be related to his decisions for the commitments, or more specifically his free choices. Whereas their argument, which has a certain similarity to Korsgaard’s argument, has some merits to have initiated a new direction to see free will as a way to explain someone’s life, I offer limitations of this direction. Such intelligibility of free choice relies on the assumption that an agent’s choices of principles that tell his identities and characteristics are open to him. 최근 자유의지에 관한 흥미로운 주장 중의 하나는 존 피셔(J. Fischer)의 ‘서사’와 관련한 설명이다. 그것에 따르면 자유의지는 삶의 서사적 구조를 모양 지을 수 있게 해준다는 의미에서 가치가 있다. 자신의 삶에 대한 서사를 통해 삶의 방향을 정한다는 점에서 그러한 서사는 행위자에게 일종의 자유의 가능성을 열어 준다. 한편 이러한 주관적인 서사와 달리 보일 등(J.M. Boyle et al.)은 자유의지의 존재를 제삼자적인 설명의 가능성으로 제시한 바 있다. 그들은 두 가지 이해 가능성을 논하면서 새로운 방식으로 자유로운 선택 개념을 제시했는데, 개인의 삶을 설명하기 위해서 자유의지를 상정할 수밖에 없다고 주장한 것이다. 자유의지를 행위자의 삶에 대한 설명의 가능성으로 제시한 이 주장과 비슷한 유형을 코스가드(C.M. Korsgaard)에게서도 찾아볼 수 있는데, 이러한 주장이 흥미롭다는 점을 인정함과 동시에 필자는 그것의 한계를 보여준다. 이 논의를 통해 자유의지에 대한 설명은 선택의 가능성이 전적으로 열려 있다는 전제 하에서만 타당한 주장이라는 점이 밝혀진다. 그것은 삶을 설명하는 과정에서 행위자의 정체성 및 성격, 삶의 원칙을 자유의 행사로 보아야 한다는 것을 전제한다.

사삼 물 추출액의 멜라닌 형성 억제 효과

강현정,임홍진,박민철,임규상,김남권,Kang Hyun-sung,Lim Hong-jin,Park Min-chul,Lim Kyu-sang,Kim Nam-kwen 大韓外官科學會 2004 大韓外官科學會誌 Vol.15 No.1

Recently many efforts were focused to understanding the mechanical insights of melanogenesis to develop the agents for hyper-pigmentation and hypo-pigmentation. In the melanin biosynthetic pathway, tyrosinase is the rate limiting enzyme, and ${\alpha}$-melanocyte stimulating hormone(MSH) or cAMP-elevating agents stimulate melanogenesis and enhance the melanin synthesis and the tyrosinase activity. The author has analyzed the effects of Radix Trichosanthis on the basal Melanogenic activities of Bl6/F10 mouse melanoma cells, and on the ${\alpha}$-MSH or forskolin-induced melanogenesis. Radix Trichosanthis alone markedly suppressed melanin content and tyrosinase activity in a dose-dependent manner. Pretreatment of the cells with Radix Trichosanthis also suppressed the increase of ${\alpha}$-MSH(10 nM) or forskolin(20 ${\mu}$M)-induced melanin content and tyrosinase activity. The decrease in the tyrosinase activity was paralled by a decrease in the abundance of tyrosinase protein and tyrosinase promoter activity. Pretreatment of the cells with Radix Trichosanthis also inhibited the increase of forskolin(20 ${\mu}$M) induced the amount of tyrosinase protein and tyrosinase promoter activity. The results of DOPA staining revealed that pretreatment of the cells with Radix Trichosanthis showed less intensity than B16 melanoma cells stimulated with ${\alpha}$-MSH or forskolin. These results suggest that Radix Trichosanthis inhibits melanogenesis and abrogates ${\alpha}$-MSH and cAMP-induced melanogenesis in B16 melanoma cells.

Invasine Ductal Carcinoma with Osteoclast-Like Giant Cell in a Young Woman

강현정,최경운,곽희숙,설미영,김지연,Kang, Hyun-Jeong,Choi, Kyung-Un,Kwak, Hee-Suk,Sol, Mee-Young,Kim, Jee-Yeon The Korean Society for Cytopathology 2007 대한세포병리학회지 Vol.18 No.1

Mammary carcinoma with osteoclast-like giant cells is an unusual neoplasm characterized by giant cells, mononuclear stromal cells, and hemorrhage accompanying a low grade carcinoma. We present the cytological findings in a case of invasive ductal carcinoma with osteoclast-like giant cells that was initially confused with a fibroadenoma, due to its well-demarcated and soft mass and the young age of the patient. A 28-year-old female presented with a 4.5 cm, well demarcated, soft and nontender mass in the right breast. Fine needle aspiration cytology (FNAC) showed a combination of low grade malignant epithelial cell clusters and osteoclast-like giant cells. The atypical epithelial cells were present in cohesive sheets and clusters. Osteoclast-like giant cells and bland-looking mononuclear cells were scattered. An histological examination revealed the presence of an invasive ductal carcinoma with osteoclast-like giant cells. We report here the cytological findings of this rare carcinoma in a very young woman. The minimal atypia of the epithelial cells and its soft consistency may lead to a false negative diagnosis in a young woman. The recognition that osteoclastlike giant cells are rarely present in a low grade carcinoma, but not in benign lesion, can assist the physician in making a correct diagnosis.

[토론문] <위기청소년의 인성교육을 위한 음악치료교육 프로그램: 지역사회 협력모델을 중심으로>의 토론문

강현정 한독교육학회 2021 한독교육학회 학술대회 자료집 Vol.2021 No.-

한국인의 관상동맥 석회화 수치와 대사증후군, 고감도 C-반응성 단백과의 관련성

강현정,문운현,문일봉,곽종길,김미현 (사)한국방사선산업학회 2020 방사선산업학회지 Vol.14 No.1

Recently, an increase in metabolic syndrome increases the rate of transshipmentand risk and mortality in cardiovascular systems, and it is important to prevent improvementof risk factors before developing symptoms as a result of high coronary heart disease. Thisstudy is intended to identify the association of metabolic syndrome with hs-CRP and coronaryartery calcium score and use them as a basis for assessing future cardiovascular disease risks. We investigated 413 adults older than 20 (male: 260, female: 153) who visited Korea Associationof Health Promotion, Gwangju-Jeonnam Branch. and had medical check such as a scientificexamination including Blood pressure (Diastolic BP, Systolic BP, Uric acid), Basic inspection(height, weight, waist circumference) and, Blood test (Fasting plasma Glucose, HDL-Cholesterol,Triglycerides, hs-CRP, Total cholesterol, γ-GTP, LDL-cholesterol, total Bilirubin, e-GFR), andCoronary artery calcium score test together. The risk of metabolic syndrome increased as ageincreased, waist circumference increased, systolic blood pressure increased, triglyceride levelincreased, fasting blood glucose level increased, and LDL cholesterol increased. The greater theuric acid level, age increased, the more likely a person with diabetes affects the coronary arterycalcium score (p<0.05). Risk factors of metabolic syndrome may affect coronary artery calciumscore and are therefore considered necessary to manage cardiovascular disease risk factors.

Effect of different chlorhexidine application times on microtensile bond strength to dentin in Class I cavities

강현정,문호진,신동훈 대한치과보존학회 2012 Restorative Dentistry & Endodontics Vol.37 No.1

Objectives: This study evaluated the effect of 2% chlorhexidine digluconate (CHX)with different application times on microtensile bonds strength (MTBS) to dentin in class I cavities and intended to search for ideal application time for a simplified bonding protocol. Materials and Methods: Flat dentinal surfaces with class I cavities (4 mm x 4 mm x 2 mm) in 40 molar teeth were bonded with etch-and-rinse adhesive system, Adper Single Bond 2 (3M ESPE) after: (1) etching only as a control group; (2)etching + CHX 5 sec + rinsing; (3) etching + CHX 15 sec + rinsing; (4) etching + CHX 30 sec + rinsing; and (5) etching + CHX 60 sec + rinsing. Resin composite was builtup with Z-250 (3M ESPE) using a bulk method and polymerized for 40 sec. For each condition, half of the specimens were immediately submitted to MTBS test and the rest of them were assigned to thermocycling of 10,000 cycles between 5°C and 55°C before testing. The data were analyzed using two-way ANOVA, at a significance level of 95%. Results: There was no significant difference in bond strength between CHX pretreated group and control group at the immediate testing period. After thermocycling, all groups showed reduced bond strength irrespective of the CHX use. However, groups treated with CHX maintained significantly higher MTBS than control group (p < 0.05). In addition, CHX application time did not have any significant influence on the bond strength among groups treated with CHX. Conclusion: Application of 2% CHX for a short time period (5 sec) after etching with 37% phosphoric acid may be sufficient to preserve dentin bond strength.