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요석에서 Therasonic LTS와 SDS-5000 기종을 이용한 체외충격파쇄석술의 치료성적
강석찬,류지간,윤상민 대한비뇨의학회 2005 Investigative and Clinical Urology Vol.46 No.3
Purpose: We compared the clinical efficacy of Therasonic LTS(piezoelectric type) with that of SDS-5000 (spark gap type) for the management of urinary stones. Materials and Methods: We evaluated 516 patients treated with Therasonic LTS, between June 1996 and April 2001, and 314 treated with SDS-5000 between September 2001 and January 2003. We compared the average success rates and shock wave sessions according to the stone sizes and locations, and also verified the complications related to the therapies. Results: The total success rates of Therasonic LTS and SDS-5000 were similar(92.6 and 94.6%, respectively), with no difference according to stone location and size. However, the average shock wave sessions were significantly lower in the group treated with SDS-5000(2.5±1.8 sessions) compared to the group treated with Therasonic LTS(3.1±1.9 sessions)(p<0.05). The cumulative success rates were 64.3 and 77.1%, respectively, at the completion of session 3, and 82.2 and 88.2%, respectively, at the completion of session 5. The complication rates associated with the therapies were 8.9 and 6.9%, respectively, consisting of pain, gross hematuria, steinstrasse and acute pyelonephritis, most of which were successfully controlled by conservative treatment. Conclusions: SDS-5000 lithotripsy is more efficient than Therasonic LTS in terms of shock wave sessions.
강석찬,박인원,이강렬,남정이 ( Seok Chan Kang,In Won Park,Kang Ryul Lee,Jeong E . Nam ) 생화학분자생물학회 1985 BMB Reports Vol.18 No.2
One of the hitherto not characterized precursor tRNAs in yeast, which was previously designated as RNA 9a, was identified to be a precursor to tRNA₂^(LYs), by comparing the fingerprints of RNA 9a and spliced product of RNA 9a. Minor base analysis of RNA 9a showed that its 5`-end nucleotide was pψp like in native tRNA₂^(Lys), and also that the bases positioned at 34, 37, and 47 are not modified at the precursor level. We also found that splicing enzyme from temperature sensitive mutant cells of yeast had the splicing activity even at the nonpermissive temperature.
Aspergillus nidulans 의 RNA 연결효소 계를 사용한 효모의 tRNA3 반분자들의 연결반응
강석찬,박인원,남정이 ( Seok Chan Kang,In Won Park,Jeong E . Nam ) 생화학분자생물학회 1985 BMB Reports Vol.18 No.2
Using yeast tRNA3^(Leu) half molecules produced by a yeast splicing enzyme, we have detected an ATP dependent RNA ligase activity in extracts of Aspergillus nidulans. Sequence analysis of the ligation products shows that ligated junction has the 2`-phosphomonoester, 3`,5`-phosphodiester linkages,…-N-P-P- N-…, as have been observed in yeast, wheat germ, and Chlamydomonas by other workers. The experimental data suggest that splicing of precursor tRNAs in Aspergillus nidulans occurs via the similar pathways as in other eucaryotes indicated above.