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고형균,Koh Hyung-Kyun 대한침구의학회 2001 대한침구의학회지 Vol.18 No.6
Objective : Modern acupuncture research often utilizes the methodology of animal experiment where animal acupoints(AA) are stimulated and the results observed. There hasn't been any consensus on the AA locations yet, but it is integral for the locations to be defined in detail for any animal experiment. Methods : The review of 24 original articles published in the Journal of Korean Acupuncture and Moxibustion Society for recent one year which utilized animal experiment methodology revealed that AA are located primarily by the method of transposition from human acupoints. Only a few of those AA were defined in detail. ST-36, CV-12, GB-34, BL-23 were among the most frequently used AA. Results & Conculsion : Transpositional Ⅲ acupoint system of mouse is proposed, which includes 3 points of LU meridian, 4 of LI, 10 of ST, 8 of SP, 3 of HT, 4 of SI, 26 of BL, 2 of KI, 4 of PC, 3 of TE, I1 of GB, 6 of LR, 8 of CV and 19 of GV.
자가면역질환의 봉독요법에 대한 Pubmed 검색을 통한 고찰
고형균,이윤호,이웅경 대한침구학회 2001 대한침구의학회지 Vol.18 No.6
Objective & Method : To identify current state of bee venom therapy(BVT) research as a treatment of autoimmune diseases, we reviewed the PubMed electronic database. 9 articles with clinical implications were discussed. Results : BVT is reported as effective in the treatment of such autoimmune related diseases as rheumatoid arthritis and insulin dependent diabetes mellitus in animal experiment, The lack of evidence on BVT as a treatment of multiple sclerosis deters us from reaching any determination. There also lacks firm evidences of immune response regulative or anti inflammatory mechanism of BVT. No clinicla trial was found. Conculsion : This review raises the urgent need of study to provide scientific and clinical evidences.
고형균(Hyung Kyun Koh) 대한침구학회 2001 대한침구의학회지 Vol.18 No.6
Objective : Modern acupuncture research often utilizes the methodology of animal experiment where animal acupoints(AA) are stimulated and the results observed. There hasn`t been any consensus on the AA locations yet, but it is integral for the locations to be defined in detail for any animal experiment. Methods : The review of 24 original articles published in the Journal of Korean Acupuncture and Moxibustion Society for recent one year which utilized animal experiment methodology revealed that AA are located primarily by the method of transposition from human acupoints. Only a few of those AA were defined in detail. ST-36, CV-12, GB-34, BL-23 were among the most frequently used AA. Results & Conculsion : Transpositional Ⅲ acupoint system of mouse is proposed, which includes 3 points of LU meridian, 4 of LI, 10 of ST, 8 of SP, 3 of HT, 4 of SI, 26 of BL, 2 of KI, 4 of PC, 3 of TE, I1 of GB, 6 of LR, 8 of CV and 19 of GV.
권기록,고형균,Kwon, Gi-Rok,Koh, Hyung-Kyun 대한침구의학회 2000 대한침구의학회지 Vol.17 No.1
The immune response of Bee Venom Therapy is commonly appear in clinics. It is whole body delayed allergy type and generally like fatigue. Therefore, in order to analysis the clinical form, we have observed immune response of 100 patients who visited Sangji University Oriental Medical Hospital and treated Bee Venom Therapy over 10 times from November 1998 to October 1999. The results were summarized as follows. 1. The distribution of Sex was 60 females, 40 males, and the average of patients age was $50.6{\pm}1.5years$. 2. The distribution of disease was degenerative arthritis, HIVD of L-spine, RA, etc. 3. The total treated time is 2765 and is observed 361 immume responses. 4. The average of keeping time in immume response is $11.8{\pm}0.6(hr)$, and the cases of over 24hrs is occupied 24.0%. 5. In the correlation between treated times and immume response is generally in inverse proportion. 6. The general aspect of immume response is chilling, heating, powerless, headache, dizziness, etc. 7. $M{\ddot{u}}ller$ Grade II-III was observed only 1%.
PubMed 검색을 이용한 관절염 관련 봉독 연구에 대한 고찰
김태우,고형균,박동석,이재동,Kim, Tae-Woo,Koh, Hyung-Kyun,Park, Dong-Seok,Lee, Jae-Dong 대한침구의학회 2001 대한침구의학회지 Vol.18 No.5
Objective : To research the trends of the study related to bee venom and arthritis, and to establish the hereafter direction of the study on bee venom herval acupuncture. Method : We searched in PubMed, with bee venom and arthritis (with abstract). Results : 1. We searched15 Papers, and the pattern of the was as fallows: Experimental study(13 Papers), Epidemiologic study(2), Review study(1). 2. The type of the experimental studies(12 Papers) was as follows: In vivo(6 Paper), In vitro(6). And the involved components of bee venom were as follows: Bee venom itself(6 Papers), Melittin(3), PLAP(1), PLAP & Melittin(1), Adolapin(1). 3. Among the experimental studies(12 Papers), the mechanism of inflammation was 10 papers (Inhibition 7, Inducer 3), and the effect of bee venom herbal acupuncture therapy were 2 papers.