http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
한상욱,조용관,정재연,박현진,김영배,남기택,김대용,주희재,최준혁,김진홍,이기명,김명욱,함기백,Han Sang-Uk,Cho Yong-Kwan,Chung Jae-Yun,Park Hyun-Jin,Kim Young-Bae,Nam Ki-Taek,Kim Dae-Yong,Joo Hee-Jae,Choi Jun-Hyuk,Kim Jin-Hong,Lee Ki-Myung,Kim 대한위암학회 2002 대한위암학회지 Vol.2 No.2
In spite the fact that H. pylori infection might be the causative organisms of acute and chronic gastritis, peptic ulcer diseases and the definition as the class I carcinogen by WHO IARC, still debates exist about the relationship between H. pylori and gastric carcinogenesis. Epidemiological and animal studies demonstrated a link between gastric cancer and chronic infection with H, pylori, but the exact mechanism responsible for the development of gastric cancer in H. pylori-infected patients still remain obscure. In order to declare the clear association, definate evidences like that decrement in the incidence of gastric cancer after the eradication of H. pylori in designated area compared to noneradicated region or the blockade of specific mechanism acting on the carcinogenesis by H. pylori infection. The other way is to identify the upregulating oncogenes or downregulating tumor suppressor genes specifically invovled in H. pylori-associated carcinogenesis. For that, we established the animal models using C57BL/6 mice strain. Already gastric carcinogenesis was developed in Mongolian gerbils infected with H. pylori, but there has been no development of gastric cancer in mice model infected with H. pylori after long-term evaluation. Significant changes such as atrophic gastritis were observed in mice model. However, we could observe the development of mucosal carcinoma in the stomach of transgenic mice featuring the loss of TGF-beta sig naling by the expressions of dominant negative forms of type II receptor specifically in the stomach. Moreover, the incidence of gastric adenocarcinoma was significantly increased in group administered with both MNU and H. pylori infection than MNU alone, signifying that H. pylori promoted the gastric carcinogenesis and there might be host susceptibility genes in H. pylori-associated gastric carcinogenesis. Based on the assumption that chronic, uncontrolled inflammation might predispose to carcinogenesis, there have been several evidences showing chronic atrophic gastritis predisposed to gastric carcinogenesis in H. pylori infection. Although definite outcome of chemoprevention was not drawn after the longterm administration of anti-inflammatory drug in H. pylori infection, the actual incidence of atrophic gastritis and molecular evidence of chemoprevention could be obtained. Selective COX-2 inhibitor was effective in decreasing the development of gastric carcinogenesis provoked by H. pylori infection and carcinogen like in chemoprevention of colon carcinogenesis.
한상욱,최재용,한정희,이춘원,김임순,전숙진 한국환경영향평가학회 2000 환경영향평가 Vol.9 No.2
Environmental monitoring system has been adopted and supplemented as inspection measures for the quantitative and qualitative changes of environmental impact assessment (EIA). Meanwhile it has been continuously pointed out that there is insufficient connection between environmental monitoring system and EIA. Often the agreed environmental impact assessment has not been fulfilled due to the argument of the cost, timing and situations of construction sites. Thus the purpose of this study is in search of the rationalized environmental monitoring system in order to harmonize the development and environmental conservation through the improvement of unreasonable aspects of the current EIA execution process. As to comply with the purpose, this research was carried out with three different but complimentary sources: environmental laws and regulations, foreign case studies of Japan, U.S.A. and Canada, and interviews with 73 experts. Finally, improved environmental monitoring system has been introduced reflecting the present process of EIA.
한국잔디에 한지형잔디 덧파종에 따른 잔디품질, 녹색기간 및 밀도에 미치는 영향
한상욱,소호섭,최병열,원선이,이상덕,강창성 한국잔디학회 2017 Weed & Turfgrass Science Vol.6 No.4
This study was conducted to examine the effect of cool-season grass overseeding on the green period, turf quality and density in zoysiagrass lawn. Treatments were perennial ryegrass (PR) overseeding (60 g m-2) on medium-leaf type zoysiagrass, Kentucky bluegrass (KB) overseeding (20 g m-2) on medium-leaf type zoysiagrass and narrow-leaf type zoysiagrass, and no overseeding on medium-leaf type zoysiagrass. Overseeding of KB or PR effectively provided quality improvement of zoysiagrass lawn by extending green-period about one month in spring and two months in fall season. PR overseeding showed quick green cover within 2-3 weeks but decreased the quality of overseeded zoysiagrass lawn during the summer season. Whereas, KB overseeding showed slow green cover taking two to three month after seeding but provided stable and good turf quality throughout the years. KB or PR overseeding significantly increased the turf density of zoysiagrass lawn except the period of summer depression of PR. The ground coverage of cool-season grasses ranged from 30 to 80% with considerable seasonal variation. As a result, KB and PR have their strengths and weaknesses as an overseeding material. Thus, the use of KB and PR as a mixture would provide better overseeding performance in zoysiagrass lawn. 본 연구는 녹색유지 기간이 6-7개월에 불과한 한국잔디로 조성된 잔디밭에 한지형잔디 종자를 덧파종하여 잔디밭의 녹색기간 연장, 잔디품질, 잔디밀도 등을 평가하기 위하여 수행되었다. 처리내용은 대조구로 한국잔디(중엽형)를 포함하여 퍼레니얼 라이그래스(60 g m-2)를 중엽형 한국잔디에 덧파종 처리와 켄터키 블루그래스(20 g m-2) 를 중엽형과 세엽형 한국잔디 ‘세밀’에 덧파종 처리를 두어 2014년 부터 2016년까지 조사하였다. 한국잔디에 켄터키 블루그래스 또는 퍼레니얼 라이그래스 덧파종으로 월동 전 2개월, 월동 후 봄철 녹화기에 1 개월로 총 3개월 정도의 녹색기간 연장으로 품질유지 효과를 보였다. 퍼레니얼 라이그래스를 덧파종 하였을 때 발아 및 초기생장이 빨라 덧파종 후 2-3주만에 녹색기간 연장효과를 볼 수 있었으나, 고온 다습한 여름철 기간 동안에는 하고현상으로 품질 저하가 나타났다. 이에 반해 켄터키 블루그래스로 덧파종한 경우에는 발아 및 초기 생육이느려 가을 파종시 당년에 뚜렷한 월동전 녹색기간 연장 효과를 볼 수 없었으나, 이듬해부터는 하절기를 포함하여연중 안정적인 품질 및 녹색 유지 효과를 보였다. 세엽형 한국잔디에 켄터키 블루그래스 덧파종 처리가 중엽형 잔디 처리에 비해 균일도가 좋아 품질 평가가 높게 나타났다. 덧파종은 퍼레니얼 라이그래스의 하고현상 발생시기를 제외하고는 한국잔디의 잔디밀도를 유의하게 향상시키는 효과를 나타냈다. 덧파종한 한지형잔디의 피복률은 계절과 초종에 따른 변화를 보였고 약 30-80%의 피복률을 나타냈다. 본 시험결과 퍼레니얼 라이그래스는 덧파종 후 빠른 피복도와 뚜렷한 녹색기간 연장효과는 있으나 하절기 품질저하를 보였고, 켄터키 블루그래스 덧파종은 초기 생육은 느리나 연중 안정적인 품질유지가 가능한 특성을보여 덧파종시 2종을 혼용하여 사용하는 것이 바람직할 것으로 판단되었다.