약물로 인해 유발된 좌불안석증에서 세로토닌 차단제인 Cyproheptadine의 효과

정동선,박인준,권영준,정희연,한선호 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.5

목 적 : 약물로 인해 유발된 좌불안석증은 항정신병 약물로 치료받은 환자에게서 자주 발생한다. 항세로토닌 제제인 Cyproheptadine은 좌불안석증 환자들을 치료키 위해 사용되어져 왔다. 방 법 : 21명의 항정신병 약물로 치료받은 좌불안석증을 동반한 환자들이 4일간에 걸쳐 하루 16mg의 Cyproheptadine을 투여 받았다. 좌불안석증에 대한 평가는 Barnes' rating scale을 이용하여 이루어졌다. 우울증과 정신병증상의 정도가 Brief psychiatric rating scale(BPRS)와 Hamilton rating scale for depression(HAM-D)에 의해 평가되어졌다. 결 과 :좌불안석증을 보인 대부분의 환자들이(20/21) Cyproheptadine 치료에서 호전을 보여주었다. 치료기간에 정신병이나 우울증의 악화는 없었다. Cyproheptadine 투여가 중단되었을 때 좌불안석증의 증상은 악화되었다. 결 론 : Cyproheptadine은 약물로 인해 유발된 좌불안석증 치료에 유용하다. Objective : Neuroleptic Induced Akathisia(NIA) often occurs in neuroleptic treated patients. Cyproheptadine, an antiserotonergic agent, was used to treat neuroleptic induced akathisia. Method : In an open trial 21 neuroleptic-treated patients with akathisia were administrated Cyproheptadine(16mg/day) over 4 days. Assessment of akathisia was evaluated using Barnes' rating scale(BAS) for neuroleptic induced akathisia. The degree of depression and psychosis were assessed by brief psychiatric rating scale(BPRS) and Hamilton rating scale for depression(HAM-D). Result : Most patients(20 of 21) with neuroleptic induced akathsia(NIA) showed improvement under the treatment of cyproheptadine. There was no aggravation of psychosis or depression during the treatment. Symptoms of akathisia aggravated when cyproheptadine was discontinued. Conclusion : Cyproheptadine may be useful in the treatment of neuroleptic induced akathisia(NIA).

精神分裂症 臨床型의 特徵 및 그症狀에 對한 硏究

韓善浩 고려대학교 의과대학 1972 고려대학교 의과대학 잡지 Vol.9 No.1

勤勞 및 非行靑少年의 精神病理學的 硏究

韓善浩 순천향의과대학 1979 Journal of Soonchunhyang Medical Science Vol.2 No.2

In this study, it was aimed to reveal the psychopathological characteristics of the working adolescents and the juvenile delinpuents through the MMPI test. The subjects of the study were 203 male delinquents and 98 female delinquents, 109 malemale working adolescents and 90 female working adolescents. MMPI test was hiven to all 500 adolescents. The results were as follows: 1. F, Pa, Pt, and si scale were the high scores in the working adolescents and the delinquents compared with the normal akolescents. Between the working akolescents and the delinquents, the scores in these scales were higher for the delinquents than for the working akolescents, especially the Sc score. 2. In the delinquency, the delinquency sxale and the psychopathological scale, (critical itens), the scores for the delinquents were higher, and the scores for the working akolescents were also suggestive that the working group may have more problens than the normal adolescents. 3. fifty sevenpoint six percentage of the male delinquents and 29.4% of the male working adolescents were expected doing misdemeanour and for the female, 68.4% of the delinquents and 30.0% of the working group were expected doing so. 4. For the males, there is no difference in the frequency ratio of the psychopathological seriousness for the non expected delinquency group and the expected delinquency group respectively. But for the females, the psychopathological seriousness were the high scores for the non expected delinquency group. 5. from the previous results, it could be surmised that the working akolescents may have the delinquency and the psychopathological seriousness and that for the delinquents, the delinquency is remarkable at first but the psychopathological seriousness is a more important factor of their misdemeanour. Especially for the females, their psychopathological problems effected their misdeeds more than for the males.

양극성장애환자의 정신사회적 스트레스에 관한 연구

권영준,한상우,한선호 순천향대학교 1990 논문집 Vol.13 No.1

The psychosocial stressors experienced in the 6 months prior to the admission were studied in 62(27 male and 35 female) inpatients who mets DSM-Ⅲ criteria for bipolar disorder and were hospitalized in the Neuropsychiatric department of Soonchunhyang University Hospital from January 1987 to August 1989. The results were as follows; 1. Among the 249 cases, 36(58.1%) cases had the psychosocial stressors prior to admission. 2. 40.7% of male cases and 71.4% of female cases had the psychosocial stressors prior to admission. Female cases had significantly higher relation to the psychosocial stressors. 3. By the age variable, there was not significant difference in relation to the psychosocial stressors prior to admission. 4. By the different educational level, there was not significant difference in relation to psychosocial stressors prior to admission. 5. By the occupation variable, there was not significant difference in relation to the psychosocial stressors prior to admission. 6. The frequency of the psychosocial stressors was in the order of occupational problems(36.1%), other interpersonal problems(22.1%), financial problems(11.1%) conjugal problems(11.1%).

호스피스들의 임종환자에 대한 태도조사

박인준,정한용,한선호 순천향대학교 1990 논문집 Vol.13 No.3

As the modern medicine advances with time, the chronic debilitating disease has become the leading cause of death, and the terminally ill and dying patients has been increased. So the managent of dying patients has become important problem in the medical practices and it is difficult for doctors to tell the patient that he or she is an dying. Whether to tell the truth or not, has been a major problem for the dying patients. The authors conducted a research to investigate the attitudes of 43 hospices toward the dying patients. 1) The 92.8% of the respondents agreed to informing the dying patinet of his prognosis. The most common rationale for informing the patient was that the patient should prepare for death psychologically, and the patient must be given the opportunity to take remaining affairs. 2) The most frequently considered pre-requisite for disclosure was the emotional stability. And items such as agreement of families, and religion were followed. 3) The 54.8% of respondents thought that it was most proper to tell the patient when he vaguely knew about his prognosis. 4) The 42.9% of respondents chose the physician-in-charge as the most appropriate person to inform the patient, the families of patinet, a minister were followed. 5) The 60.5% of respondents replied that the method of telling the truth was "to take several days with step by step". 6) As to what a dying patient needed most, more frequently chosen items were religious help, hospice care & care of family members. 7) The 55.8% of respondents agreed that psychiatric treatment for a dying patient i good idea. 8) The 41.9% of respondents thought that a dying patient suffered from fear of unknown. Fact, physical discomfort and separation were followed. 9) In the questionaire of "If you are on the process of dying, whether you want to know or not the truth of impending death", all respondents (100%) replied that they want to know the truth. 10) In the questionaire of "The meaning of death", the 45.2% of respondents chose that the death is lie and a beginning of the new life. 11) 52.4% of respondents preferred a dying patient to be cared by hospice after telling the truth. 12) In the questionaire of "Are you satisfied with the treatment of a dying patient", 51.3% of respondents replied that they are poorly satisfied with a emotional and psychological support to a dying patient.

정신과 입원환자의 갑상선 기능

신수철,정한용,한선호 순천향대학교 1990 논문집 Vol.13 No.3

The authors studied the relationship between the psychiatric disorder and thyroid function by measuring the serum T₃, T₄and TSH levels with the method of radio-immunoassay. Subjects were consisted of 22 schizophenic, 12 depressed, 15 manic patients who were treated at the department of Neuropsychiatry, Soonchunhyang University Hospital from January 1990 to June 1990, and the controls were consisted of 20 healthy medical patients who were admitted for human dock. The results were as following; 1) The serum T₃and TSH of the schizophrenic patients were significantly lower than those of the control group (T3 : p<0.0005, TSH : p<0.01). 2) The serum T₃and TSH of the depressed patients were significantly lower than those of the control group (T3 : p<0.01, TSH : p<0.025). 3) The serum T₃and T₄of the manic patients were significantly higher than those of the control group(T₃: p<0.01, T₄: p<0.05).

지속성 복막투석 환자와 혈액투석 환자의 우울과 불안 정도에 대한 비교 연구

정재용,한선호 大韓神經精神醫學會 1994 신경정신의학 Vol.33 No.5

만성 신부전증 환자중 CAPD와 혈액투석이라는 각각 다른 투석치료를 하고 있는 환자에서 치료도중 나타나는 우울과 불안감을 서로 비교해서 그 차이점을 알아보기 위하여 1993년 7월부터 1993년 10월까지 순천향의대 부속병원 인공신장실에서 치료중인 CAPD군 29명, 혈액투석군 41명을 대상으로 자기보고형 심리검사도구인 Beck Depression Inventory(BDI), State-Trait Anxiety Inventory(STAI) 및 면담에 의해 얻어지는 객관적인 심리검사도구인 Hamilto Rating Scale for Depression(HRAS)와 Hamilton Rating Scale for Anxiety(HRAS)를 사용하여 다음과 같은 결과를 얻었다. 1) CAPD군은 Hamilton Rating Scale for Depression(HRSD)검사 결과 혈액투석군 보다 우울증상이 유의하게 낮았다. 2) CAPD군은 Beck Depression Inventory(BDI)검사 결과 혈액투석군과 유의한 차이를 보이지 않았다. 3) 불안의 정도는 두 군사이에 통계적으로 의미있는 차이가 없었다. 결론적으로 CAPD 환자들은 혈액투석 환자에 비해 객관적인 우울증상은 덜 하지만 불안의 증상은 치료방법 자체로 영향을 받지 않는다는 결과를 보여주었다. This study was conducted to investigate the difference of depression and anxiety developed in the patients on CAPD and Hemodialysis. The authors survey 29 patients on CAPD treatment and 41 patient on Hemodialysis at Soonchunhyang University Hospital from Jul. 1993 to Oct. 1993. Depression and anxiety were evaluated with the Beck Depression Inventory and the State-Trait Anxiety Inventory known as self report assessment scale, and those with the Hamilton Rating Scale for Depression and Hamilton Rating Scale for Anxiety as objective assessment scale by interview. The results were as follows : 1) The CAPD group was significantly less depressed than the Hemodialysis group on Hamilton Rating Scale for Depression. 2) The Beck Depression Inventory showed no significant difference in depression between the CAPD group with the Hemodialysis group. 3) There was no significant difference in anxiety between two groups. In conclusion, authors suggest that objective depressive symtomes were less in the CAPD group, but anxiety symptomes were not influenced by treatment modality itself.

For Layman 평신도를 품에 안고 : 주께 무릎 꿇고_기도의 힘 ; 금식기도는 자아를 죽이는 작업

한선호 기독교대한성결교회 출판부 2010 활천 Vol.674 No.-

양극성장애 조증 환자에서 Verapamil의 효과

김광기,한선호 순천향대학교 1992 논문집 Vol.15 No.2

This study was made in order to evaluate the effect of verapamil in bipolar disorder manic patients. Three patients were diagnosed as bipolar disorder manic based on DSM-Ⅲ-R criteria. We observed improvement of manic symptoms while the patients received verapamil 320mg/day tid. However, one case developed depression when given a course of verapamil treatment. The others were improved wighout depression.

알콜 중독환자 가족의 결속력. 적응력 평가척도와 가족기능도지수에 대한 연구

신행호,한선호 순천향대학교 1993 논문집 Vol.16 No.2

FACES-III devised by Olson and Family APGAR Score by Smilkstein are being used as tools of evaluating family function. We selected 33 family members of alcoholism who were admitted to the Neuropsychiatric department of university, college of medicine etc, and as a control group, we took 50 cases of adult. We had researched the family function and tried to get beneficial materials for the understanding of the alcoholism and for the better management of them. The results were as follows: 1. Out of 33 people in alcoholic family were 9 men(27.3%) and 24 women(72.7%). age distribution of alcoholic family is as follows : 2th decade were 9 cases(27.3%), 3rd decade were 14 cases(42.4%), 4th decade were 10 cases(30.3%). 2. In FACES-III cohesion of the alcoholic family, there were 6 cases(18.2%) in "disengaged" and 13 cases(39.4%) in "separated" and 8 cases(24.2%) in "connected" and 6 cases(18.2%) in "enmeshed". 3. In FACES-III adaptability of the alcoholic family, there were 22 cases (66.7%) in "chaotic" and 4 cases(12.1%) in "flexible" and 5 cases(15.2%) in "structed" 2 cases(6.1%) in "rigid". In view of family adaptability, "chaotic" cases of the alcoholic family significantly higher than the control group and "flexible" cases of the alcoholic family were significantly lower than the control group. but family cohesion showed no significant difference between the 2 groups. 4. "balanced" families were lesser and "mild-rang"families were more than the control group. 5. In Family APGAR Score of the alcoholic family, the average score was 5.7 and in that of the control group, it was 6.4. Family APGAR Score showed no significant difference between the 2 groups.