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      • KCI등재

        Surgical Outcomes of Cor Triatriatum Sinister: A Single-Center Experience

        김동희,권보상,김동희,최은석,윤태진,박천수 대한심장혈관흉부외과학회 2022 Journal of Chest Surgery (J Chest Surg) Vol.55 No.2

        Background: We investigated surgical outcomes after the surgical repair of cor triatriatum sinister (CTS). Methods: Thirty-two consecutive patients who underwent surgical repair of CTS from 1993 through 2020 were included in this study. The morphological characteristics, clinical features, and surgical outcomes were described and analyzed. Results: The median age and body weight at operation were 9 months (interquartile range [IQR], 3–238 months) and 7.5 kg (IQR, 5.8–49.6 kg), respectively. There were 16 males (50%). According to the modified Lucas classification, type IA (classical CTS) was most common (n=20, 62.5%). Atrial septal defect was associated in 22 patients (68.8%) and anomalous pulmonary venous return in 8 patients (25%). Pulmonary hypertension was preoperatively suspected with a high probability in 18 patients (56.3%). There was 1 early death (3.1%) after emergent membrane excision and hybrid palliation in a high-risk hypoplastic left heart syndrome patient. There were no late deaths. The overall survival rate was 96.9% at 15 years post-repair. No early survivors required reoperation during follow-up. Most survivors (31 of 32 patients, 96.9%) were in New York Heart Association functional class I at a median follow-up of 74 months (IQR, 39–195 months). At the latest echocardiography performed at a median of 42 months (IQR, 6–112 months) after repair, no residual lesion was observed except in 1 patient who had moderate pulmonary hypertension (mean pulmonary arterial pressure of 36 mm Hg). Conclusion: Surgical repair of cor triatriatum could be performed safely and effectively with an extremely low risk of recurrence.

      • KCI등재

        The Anticancer Effect of Inonotus obliquus Pilat (Chaga) Processed by Nanomill Technology In vivo

        김동희,등영건,윤양숙,최주봉,정현석,장병수,이규재,Kim, Dong-Heui,Teng, Yung-Chien,Yoon, Yang-Sook,Qi, Xu-Feng,Jeong, Hyun-Seok,Chang, Byung-Soo,Lee, Kyu-Jae Korean Society of Electron Microscopy 2009 Applied microscopy Vol.39 No.2

        차가버섯(Inonotus obliquus)의 추출물과 분획들은 항돌연변이, 항암, 항산화 및 면역자극 효과 등을 비롯하여 다양한 생물학적 활성을 갖는 것으로 알려져 있다. 본 연구는 나노분쇄 기법으로 제작된 10% 차가사료를 C57BL/6 생쥐에게 식이한 후 항암효과를 확인하기 위해 시행되었다. 부피평균에 의한 입도분석에 따르면 1 ${\mu}m$ 내에 포함되는 초미세 차가버섯 입자는 전체의 40%인 것으로 나타났다. 생쥐에게 B16BL6 흑색종세포를 피하로 주사한 결과, 종양의 부피(p<0.001)와 무게(p<0.01)는 초미세 차가버섯을 식이한 실험군(Nch)이 일반사료를 먹인 대조군(C)에 비해 현저히 감소하였고, 종양성장 억제율은 29.2%를 나타내었다. 흑색종 세포를 복강 내로 주사한 후 생존율을 관찰한 결과, 마리 당 평균 생존기간은 대조군과 실험군이 각각 17.7일과 26.0일이었다. 대조군이 모두 사망한 날인 35일 째 실험군의 생존율은 40%를 보여주었다. 초미세 차가입자가 소화기관에 문제를 유발시킬 수 있는 가능성 때문에 안전성을 확인하기 위해 소장과 대장을 조직학적으로 관찰한 결과 두 군 모두 형태학적 또는 병리학적 변화는 관찰되지 않았다. Extracts and fractions of Inonotus obliquus (Chaga in Russia) have been known to have various biological activities, including antimutagenic, anticancer, antioxidative, and immunostimulating effects. This study was performed to confirm anticancer effect of 10% superfine Chaga mushroom processed by nano-mill technology on C57BL/6 mice. Chaga particles belonged in the size of 1 ${\mu}m$ was about 40% after nanomill processing according to the volume distribution. As the result of subcutaneous injection of B16BL6 melanoma cells to the mice, the tumor volume (p<0.001) and tumor weight (p<0.01) was significantly decreased in the experimental (NCh) group as compared with control (C) group and the tumor growth inhibitory rate was 29.2%. On examination of survival rate after intraperitoneal injection of B16BL6 melanoma cells, the mean survival time per a mouse was 17.7 and 26.0 days in C and NCh group respectively. The survival rate of NCh group was 40% when that of C group was 0% at the 35th day. On the result of examination to confirm histological toxicity by Chaga superfine particles, both groups did not show any morphological and pathological changes in the small and large intestine under the light microscope. These results suggest that feeding of superfine Chaga produced by nanomill technique has a tumor growth inhibitory effect in vivo.

      • KCI등재

        급속열처리를 통한 알루미나 나노 템플레이트의 기공 균일도 개선에 관한 연구

        김동희,김진광,권오대,양계준,이재형,임동건,Kim Dong-Hee,Kim Jin-Kwang,Kwon O-Dae,Yang Kea-Joon,Lee Jae-Heong,Lim Dong-Gun 한국전기전자재료학회 2006 전기전자재료학회논문지 Vol.19 No.2

        Ordered nanostructure materials have received attention due to their unique physical properties and potential applications in electronics, mechanics and optical devices. To actualize most of the proposed applications, it is quite important to obtain highly ordered nanostructure arrays. The well-aligned nanostructure can be achieved by synthesizing nanostructure material in the highly ordered template. To get well-aligned pore array and reduce process time, rapid thermal anneal by an IR lamp was employed in vacuum state at $500^{\circ}C$ for 2 hour. The pore array is comparable to a template annealed in vacuum furnace at $500^{\circ}C$ for 30 hours. The well-fabricated AAO template has the mean pore diameter of 70 nm, the barrier layer thickness of 25 nm, the pore depth of $9{\mu}m$, and the pore density of higher than $1.2{\times}10^{10}cm^{-2}$.

      • SCOPUSKCI등재

        술후 통증자가조절시 Ondansetron과 병용된 Dexamethasone이 오심 및 통증 억제에 미치는 효과

        김동희 대한마취과학회 1999 Korean Journal of Anesthesiology Vol.36 No.3

        Background : The purpose of this study was to compare the effectiveness of ondansetron plus dexamethasone versus ondansetron alone in the prevention of postoperative nausea and vomiting for the patient using a patient controlled analgesia (PCA). Methods : Of sixty women having general anesthesia for total abdominal hysterectomy (TAH), thirty received intravenous ondansetron 4 mg plus 150 μg/kg of dexamethasone (Group 1) and thirty received intravenous ondansetron 4 mg plus saline 2 ml (Group 2) after awakening. Butorphanol 10 mg, ketorolac 180 mg and ondansetron 4 mg were connected to PCA pump for postoperative pain control. The severity of nausea, vomiting and pain were assessed at 0, 1, 2, 6, 12, 24, 36 and 48 hr after awakening. Results : Nausea and vomiting occurred in 5 patients in Group 1 and in 4 patients in Group 2. There were no significant differences between groups in nausea, vomiting and pain scores. Conclusions : The combination of ondansetron and dexamethasone is not more effective tha ondansetron alone in prevention of postoperative nausea, vomiting and pain for women having PCA following TAH. (Korean J Anesthesiol 1999; 36: 469∼473)

      • KCI등재

        댁내 장치의 원격 제어를 위한 UPnP 프록시 시스템

        김동희,임경식,이화영,안준철,조충래,박광로 한국정보과학회 2004 정보과학회 컴퓨팅의 실제 논문지 Vol.6 No.2

        본 논문에서는 홈 네트워크가 사설망으로 구성됨으로 인하여 인터넷과 홈 네트워크가 단절된 환경에서 사용자가 인터넷을 통하여 흠 네트워크 내부의 장치들을 제어하고 모니터링을 할 수 있는 UPnP 프록시 시스템을 제안한다. 흠 네트워크가 사설망으로 구성되는 환경에서는 댁내 장치의 광고 메시지가 인터넷으로 전송되지 않아 사용자는 댁내에 어떠한 장치가 접속되어 있는지 알 수 없으며, 사용자는 댁내의 장치에 직접 접근할 수 얼기 때문에 장치 제어 명령을 해당 장치로 전달할 수 없다 따라서 본 논문에서는 이러한 문제점을 분석하고 외부 인터넷에서 댁내 UPnP 장치들을 제어할 수 있는 방안을 제시한 후, UPnP 프록시 시스템을 설계하고 구현한다. 본 시스템의 장점으로, 사용자는 본 시스템을 사용하여 유무선 환경의 인터넷에서 기존의 댁내 환경에서의 장치 제어를 위한 프리젠테이션 문서를 이용하여 장치를 제어 할 수 있으며, HTTP 기반의 푸시 기술을 통하여 사용자는 홈 네트워크의 상태를 실시간으로 모니터링 할 수 있다. Because of a security problem and not enough IPv4 address space, the home network has been made up of private network, and it has been separated from Internet. This fact prevents people in Internet from controlling and monitoring home appliances. So, this paper designs and Implements the UPnP Proxy System which offers functions for users to control and monitor home appliances. When users are in the outside of the home network, they do not know which devices were connected in the home network because the advertisement messages of UPnP devices would not be delivered to the outside of the home network. Also, users cannot access devices directly, and their control messages are not delivered into the home network. So, this paper designs and implements the UPnP Proxy System to solve these problems. The merit of the system is that users can control and monitor home appliances in realtime using presentation web documents with the HTTP push technology.

      • KCI등재

        승강기의 인버터에 적용 가능한 보조컨버터를 활용한 12펄스컨버터에서 PQA를 이용한 FFT 고조파 성분 분석

        김동희 국제차세대융합기술학회 2023 차세대융합기술학회논문지 Vol.7 No.7

        In elevators and escalators, harmonics are the root cause of noise and heat in existing 12-pulse converters, which are applicable to inverters of motors and are commonly used. Therefore, there is an urgent need for research in the direction of reducing harmonics in the converter. Therefore, in this study, in order to analyze harmonics in a newly proposed converter using an auxiliary converter and verify and confirm the effectiveness of harmonic reduction, a 1.5kW proto-type converter was constructed and a power analyzer (Power Quality Analyzer, PQA) was used. As a result of harmonic analysis, it was confirmed that the harmonic components in the proposed converter were generally small. 엘리베이터 및 에스컬레이터에서 전동기의 인버터에 적용 가능하고, 일반적으로 많이 사용되는 기존 12 펄스컨버터에서 고조파는 소음과 발열의 근본 원인이다. 그러므로 컨버터에서는 고조파를 줄이는 방향의 연구가절실한 상황이다. 이에 본 연구에서는 보조컨버터를 활용한 새로 제안된 컨버터에서의 고조파를 분석하여, 고조파절감의 효과성을 검증하고 확인하고자, 1.5kW 축소형 컨버터를 구성하여 전력분석기(Power Quality Analyzer, PQA)를 이용하여 고조파를 분석한 결과, 제안된 컨버터에서 고조파 성분이 전반적으로 작음을 확인할 수 있었다.

      • KCI우수등재
      • 고농도 수소수음용 및 수소가스흡입의 항산화 효과

        김동희,성재신,정태을,이규재 한국물학회 2015 한국물학회지 Vol.4 No.1

        Antioxidant effects of hydrogen gas inhalation for 60 mins (75ml/min) and drinking high concentration of hydrogen water (pH 8.49±0.3, ORP 23mV, hydrogen concentration 1177ppb) were examined – for more than 30 years of age of healthy 32 males volunteers. In hydrogen water drinking group, reactive oxygen species was change to 297297.0±57.9 from 303.8±53.6 in 5 mins. In hydrogen gas inhalation group, reactive oxygen species was changed to 284.4.0±53.6 from 310.4±56.2 in 60mins. Also, The individual reduction rate of reactive oxygen species was 56.3% in hydrogen water drinking group and 68.8% in hydrogen gas inhalation group. These results show that hydrogen gas inhalation and hydrogen water drinking have antioxidant effects.

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