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종설논문 : 의사-제약회사 상호작용이 처방에 미치는 영향
홍진표 ( Jin Pyo Hong ),박상은 ( Sang Eun Park ),고윤석 ( Youn Suck Koh ) 한국의료윤리학회 2011 한국의료윤리학회지 Vol.14 No.2
The relationship between the medical profession and the pharmaceutical industry has received considerable attention in recent years in Korea. In this article we examine the impact of physician-pharmaceutical industry interaction (PPII) on physician prescriptions. While physicians` decisions concerning prescriptions are influenced by many factors, two of the most influential are the visits of sales representatives from pharmaceutical companies and the gifts and other enticements that pharmaceutical companies provide for physicians. Patients regard gifts from pharmaceutical companies as less appropriate and more influential than do physicians. Inappropriate relations between physicians and pharmaceutical companies can damage physician-patient relationships and harm the medical profession as a whole. Recent investigations in the United States and Korea have found many illegalities in physician-pharmaceutical industry interaction. The article argues for the urgent need to develop clear ethical codes and compliance mechanisms concerning PPII.
홍진표,김응권,남상민,김태임,서경률,이상엽,Alessandro Meduri 연세대학교의과대학 2012 Yonsei medical journal Vol.53 No.3
Purpose: To evaluate reliability of Fourier-domain optical coherence tomography (OCT) (RTVue), time-domain OCT (Visante), and slit-lamp adapted ultrasonic pachymetry (SL-US) in the measurement of central corneal thickness (CCT). Materials and Methods: Thirty healthy volunteers visited our clinic 3 times and fifty eyes were measured by one physician. RTVue and Visante were randomly performed, and then SL-US, in which the ultrasound probe was inserted into the Goldmann tonometry mount, was done. During the second visit, each measurement was repeated 3 times. Measurements on the second visit were averaged,and agreement among the instruments was investigated with Bland-Altman plots. Results: RTVue showed smaller repeatability coefficient than Visante and SL-US (4.7, 8.3, and 7.7 μm, respectively). Intersession reproducibility of RTVue and Visante was worse than their repeatability. CCT of RTVue was estimated to be maximally different by 11.8 μm from CCT of Visante and 8.8 μm from CCT of SL-US. The repeatability coefficient of SL-US was 7.7 μm and its reproducibility was similar to the repeatability. Conclusion: CCT measured by RTVue showed good reliability and generally agreed with Visante and SL-US. SL-US was as reliable as triple touching conventional US even with a single touch on the cornea.
홍진표,정훈성,장용오,박찬,김민준,김민주,전경진,김영권 한국농약과학회 2021 한국농약과학회 학술발표대회 논문집 Vol.2021 No.11
산림해충의 방제를 위하여 수목의 잎에 약액을 살포하는 엽면살포 방법은 여러 차례 살포로 비용이 많이 발생하고 살포되는 약액이 비산되어 작업자 또는 주변에 2차 피해를 야기할 수 있다. 이러한 점들을 개선하기 위하여 수목에 천공을 하고 약액을 주사하는 나무주사제가 개발되었고, 엽면살포에 비해 빠른 약효, 비용의 절감과 약제 비산이 없어 2차 피해를 방지할 수 있다는 장점이 있다. 나무주사제는 수목 자체의 흡입력을 이용하는 중력식과, 주사기 내부에서 스프링 등으로 압력을 가하여 약액을 전달시키는 가압식으로 나눌 수 있다. 중력식은 약액의 주입이 너무 느리고 잔량이 발생할 수 있으며, 가압식은 약액을 밀어내는 압력이 너무 높아서 나무주사제 외부로 샐 수 있어 약효에 영향을 줄 수 있다. 본 연구에서는 기존 사용 중인 중력식과 가압식 나무주사제를 보완하고자 발포식 나무주사제를 이용하였다. 발포식 나무주사제는 발포액의 반응을 통하여 약액을 3시간 내로 빠르게 처리할 수 있고, 약액을 끝까지 밀어주어 잔량이 남지 않고, 3년 가혹조건에서 발포 시 모두 양호하였다.
홍진표 安東敎育大學 1971 論文集 Vol.4 No.1
1. The purpose of this study is intended to survey the facility and establishment it primary school in Kyungpook Province for phisical education and to suggest the materials for maintenance and betterment of them as an essencial basic condition to establish the mission as well as teaching and learning of physical education. 2. As the method of this study, the following questionaires were used; A. The actual condition of a common apparatus. B. The actual condition of an utensil for free play. C. The actual condition of an instrument play. D. The actual condition of the fixtures and utensil for race. E. The actual condition of utensil for ball play. F. The comparision of present condition with standard. 3. The period and object of this study are; A. From November of 1970 to June of 1971(for 8 months) B. The 200 elementary schools were sampled for this study and 70% of them were reacted for it. 4. As the above method, the result of this study is found as follows; A. The common utensils were maintained as the minimum quantity but it should be enlarged for the children. B. As the utensils for the free play, the swing, chute, moving timber, wooden horse, see-saw, and so on should be enlarged as they are much wanted. C. As the fixture apuaratus, the -sea-saw, iron bar, balance bar and so on were prepared fairly well but others were much wanted for them. D. The establishment and fixtures for race were prepared least but needed much. E. As the utensil for ball play, the fucilities were needed much, too. F. As the fucilities for game, the 50% for the standard were prepared in the province. 5. This study has suggested some problems mentioned above to solve them for teaching and learning of he physical education as improving the fucilities wanted at the primary school in the province.
정상인에게 Nortriptyline 경구 투여가 혈장 3-Methoxy-4-Hydroxyphenethyleneglycol 농도에 미치는 영향
홍진표,신상구,우종인 대한신경정신의학회 1992 신경정신의학 Vol.31 No.2
Ths purpose of this study was to examine the pharmacological effect of nortriptyline, the secondary amine antidepressant, on noradrenergic system from the point of pharmacokinetics and pharmacodynamics. Twelve healthy male volunteers took single dose of nortriptyline (20mg, 50mg). Plasma nortriptyine and M H P G concentration were measured periodically in 0, 1, 3,5, 8,12, 24,28,32,48 hours after then by HPLC method. Summary of results were as follows : 1) Plasma peak levels of nortriptyline were attained at about 5 hours after administration of the drug. Area under the plama concentraion time curve(AUC) was 297.7士 61.3hr ng/ml (20mg,N = 6 ) , 678土 102.4 hr ng/ml (50mg, N = 6) respectively, and showed proportional relationship with oral dose. 2) Plasma MHPG level was significantly decreased and maintained that condition from one to 48 hours, Reduction of MHPG level was largest in 8-12hours(up to 50O . 3) MHPG decrease showed slight delay compared with each nortriptyline concentration.