眩暈에 대한 七氣湯의 治驗例

權貞南,金塋均 대한한방성인병학회 1998 韓方成人病學會誌 Vol.4 No.1

The 49year-old female patient complained vertigo, dizziness, headache, severe pain of epigastrium that were caused by stress. That dizziness was the main manifestation of vestibula neuritis. We treated her with Chilgitang. After 5days since beginning of treatment, we obsered the patient's dizziness improved and other symptoms disappeared with dizziness such as headache, severe pain of epigastrium.

중풍 환자의 혈압 변화에 관한 임상적 고찰

권정남,김영균,최문경 대한동의생리학회,대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.6

Paralysis is a neurological disease which suffers numerous people around the world as well as Korea. It is one of the main three causes of death. The two others are cancer and hearth disease. To make matters worse, particularly, paralysis ranks top in the list of death causes of Korean people. This researcher randomly sampled and analyzed medical records of 467 patients who was hospitalized and treated at Chinese Medicine hospital of Dongeui university after they were diagnosed as having cerebral hemorrahage through Brain CT and Brain MRI photography. The researcher checked those paralyzed patients from entering till leaving the hospital in regard to their high blood pressure distribution, average blood pressure, whether they took blood pressure medicines or not, and variations in blood pressure in accordance with the time period of hospitalization and whether or not the patients took medicines treating blood pressure. In terms of high blood pressure, 283(60.6%) patients among the total surveyed in this study were found having high blood pressure provided considered based on the contraction stage of blood pressure, while 257(55%) was under an equivalent status based on the relaxation stage of the same measure. Those who suffered from high blood pressure were occupied by 102 men, 59% of the total same sex, 172, and 181 women, 61% of the total equivalent sex, 297, when evaluated based on the contraction stage mentioned above while, 90 men and 167 women, the relaxation stage. Among all of the patients with high blood pressure, that is 283(contraction stage)and 257(relaxation stage), 1(0.4%) and 2(0.8%) were respectively at their 30s, 19(6.7%) and 18(7.0%) at their 40s and 49(17.3%) and 39(15.2%) at their 50s. 111(39.2%) and 107(41.6%) 87(30.7%) and 78(30.4%), and 16(5.7%) and 13(5.1%) respectively at their 60s, 70s and 80s. These indicate that an absolute majority of high blood pressure patients was occupied by those at their 60s and 70s. When all of the 467 patients were classified in terms of hospitalization period, 201 patients (43.04%) belonged to <1 Week's Group>, followed by 140(29.98%), <2 Weeks' Group>, 82(17.56%), <4 Weeks'group> and 44(9.42%), <8 Week's Group>. Categorized in accordance to whether they had took any medicines to control blood pressure at the time of entering hospital, the total subject was divided into A,B and C groups. Out of 467 patients, in detail, 191(40.9%) became under <Group A>, 215(46.4%), <Group B> and 61(13.06%), <Group C>. For all the patients selected for the study, mean blood pressure was 153.7/94.4 when they were hospitalized and 134.6/85.3 when they left hospital. In <Group C> whose 61 members began to take blood pressure medicines during hospitalization, average blood pressure significantly decreased to 148.0/93.1 after taking the medicines from 164.3/101.3 before the treatment. Consequently, the level of blood pressure in the part of the whole patients under survey here was significantly changed or decreased after they received proper treatments and according to the time period of their hospitalization.

頭風에 關한 文獻的 考察

權貞南,曺基湖,李源哲,金永錫,裵亨燮,李京燮,具本泓 대한한의학회 1990 대한한의학회지 Vol.11 No.1

동맥내막절제술과 동맥내 스텐트 삽입술을 이용한 청색지증후군 치험 2예 : 2 Cases Report

권정남,박동은,채권묵,노병석,소병준 대한혈관외과학회 2003 Vascular Specialist International Vol.19 No.1

Klippel-Trenaunay Syndrome의 정맥 질환이 두드러진 형 1예 증례보고

권정남,박동은,채권묵,소병준 대한외과학회 2002 대한외과학회 학술대회 초록집 Vol.2002 No.10

Hemorrhagic cholecystitis: report of a case

권정남 한국간담췌외과학회 2012 한국간담췌외과학회지 Vol.16 No.3

Hemorrhagic cholecystitis is an uncommon cause of abdominal pain that can be fatal. We report a case of hemorrhagic cholecystitis in a 75-year-old male taking an anticoagulant. The patient was brought to the hospital with uncontrolled right upper quadrant abdominal pain. On computed tomography, mild gallbladder wall thickening and high density with gallstones in the gallbladder suggested acute calculous cholecystitis or hemorrhagic cholecystitis. An urgent laparoscopic cholecystectomy was performed that revealed a gallbladder filled with large blood clots and two black stones. Patients who develop hemorrhagic complications were often receiving anticoagulation therapy or had pathologic coagulopathy. An early diagnosis of this potentially fatal condition is important to facilitate urgent surgical treatment.

급성(急性) 신우신염(腎盂腎炎)의 임상적(臨床的) 고찰(考察)

권정남,김영균,류주열,Kwon, Jeong-Nam,Kim, Young-Kyun,Ryu, Ju-Yeol 사상체질의학회 2001 사상체질의학회지 Vol.13 No.2

Purpose: In general, Acute Pyelonephritis is effectively treated with the use of antibiotics. However, some antibiotics are reported to cause side effects, and the abuse of antibiotics results in the increase of the disease's tolerance to antibiotics. Recently, I have effectively treated five cases of Acute Pyelonephritis by using only Constitution - Acupuncture and Herb, and therefore I would like to report about these cases. Methods: I diagnosed Acute Pyelonephritis of these five patients by confirming symptoms and employing a urine analysis with reagent strip(Multi $stix{\circledR}$). I used Kuon's method of constitutional diagnosis for the purpose of the diagnosis of the constitutional 8 morbidities. I relied on Sungjeong(性情) and Chehyungkisang(體刑氣像) in diagnosing Sasang Constitutions(四象人). I performed acupuncture on the left and right sides, depending on 8 constitutions, by employing Chang - temperament Inflammation Formula(臟系炎症方) that is used for the treatment of all kinds of chang-temperament inflammation diseases, as well as Bactericidal Formula(殺菌方) that is used for the treatment of all kinds of bacterially caused diseases. I prescribed by consulting the appearance of disease and general symptoms of each case with Dongyi Soose Bowon(東醫壽世保元)'s prescription symptoms. Result: Two of them showing severe symptoms were hospitalized, while three others took OPD treatment. The patient who was PANCREOTONIA and Soyangin improved through hospitalization for three days, another patient who was PULMOTONIA and Taeyangin with severe symptoms, improved through hospitalization for seven days, and completely recovered through OPD treatment later. The three others took only OPD treatment, and improved within 5-7 days. Conclusion: I confirmed that each of 8-constituions and Sasang Constitutions were all treated effectively without antibiotics.

췌장의 림프상피성 낭종 1예

권성진,권정남,박동은,소병준,채권묵,문형배 대한외과학회 2003 대한외과학회 학술대회 초록집 Vol.2003 No.5

眩暈의 原因에 關한 文獻 考察

權貞南 동의대학교 한의학연구소 1997 동의한의연구 Vol.1 No.-

This study is to define the etiology of vertigo and dizziness on the basis of eastern and western medical literatures. The conclusions are as follows: 1. In oriental medicine, the etioloar of vertigo and dizziness is mainly divided into external infection(外感) and internal damage(內傷). Wind(風), cold(寒), dampness(濕), summer heat(暑) are included in the one and in the other, Ki(vital energy)(氣) and blood deficiency(氣血虛), insufficiency of the liver and kidney(肝腎虛), retention of phlegm and fluid(痰飮), emotional disorder(七情內傷) and so on. 2. The main etiology is the case caused by infirmity(虛), which is Ki(氣) of the upper portion of the body being insufficient(上氣不足), deficiency of mar개w-reservoir(髓海不足), insufficiency of liver(肝虛), blood depletion(血枯), insufficiency of YANG(陽虛), vital energy and blood deficiency(氣血虛) etc. 3. The etiology of vertigo and dizziness is contrarily mentioned as excess in the upper and dificiency in the lower(上實下虛) and deficiency of the ewer portion of the body(上虛), but both are ultimately recognized as the concept of infirmity. Furthermore, upper excess can be the case that invades the brain of the weakened body through wind-heat, phlegm-fire, dampness, etc. 4. Vertigo and dizziness arises from an abnormality of the vestibular system but less commonly can be produced by visual or somatic sensory disorders. 5. Vestibular vertigo can be caused by disease of either the peripheral or central vestibular apparatus. Peripheral causes of vertigo no peripheral vestibulopathy, Meniere's syndrome, vestibulotoxic drugs, and central causes of vertigo are cerebrovascula disease, cerebellopontine angle tumors, demyelinating disease. Systemic causes are drug, hypotension, endocrinosis. 6. In comparative study between eastern and western medicine on the etiology of vertigo and dizziness, the peripheral causes are the dysfunction of liver and kidney, wind(風), phlegm(痰), fire(火) and central causes are wind-heat(風熱), phlegm-fire(痰火), dampness(濕) which invades the brain of weakened body. Systemic causes are the insufficiency of liver and kidney(肝腎虛), vital energy and blood deficiency(氣血虛), emotional disorder(七情內傷).

배양된 흰쥐 담관 섬유모세포에 대한 간흡충 분비배설 물질의 영향

권정남,민병훈,이행숙,김수진,주경환,Kwon, Jung-Nam,Min, Byoung-Hoon,Lee, Haeng-Sook,Kim, Soo-Jin,Joo, Kyoung-Hwan 한국현미경학회 2009 Applied microscopy Vol.39 No.2

간흡충(Clonorchis sinensis)은 우리나라에서 높은 감염률(2.9%)을 나타내는 기생충으로(KAHP, 2004), 간흡충에 감염된 담관은 간흡충의 흡반에 의한 물리적 자극과 대사산물 및 분비물 등의 화학적 자극에 의해 담관염이 일어나고, 간흡충이 성장할 때 충체 주위의 담관 상피세포의 증식, 탈락, 담관 주위의 염증 및 섬유화가 일어난다. 담관 점막에 분포하는 섬유모세포는 결합조직을 구성하는 세포의 한 종류로서 세포질돌기들이 잘 발달된 형태적 특징이 있으며, 세포질 내에 세포의 형태 유지, 신호전달, 인접세포와의 연접 등에 관여한다. 또한 조직을 발달시키고, 조직이 손상된 부위에서 콜라겐 층을 형성하여 손상된 조직이 복구되도록 하기도 한다. 상처의 반흔(scar) 형성과 지방축적, 염증(inflammation) 발생 과정에서 섬유모세포의 작용이 제대로 조절되지 못하면 섬유증(fibrosis)이 발달하게 된다는 연구 보고도 있다. 본 연구에서는 정상 흰쥐에서 분리된 담관 섬유모세포와 간흡충 감염 흰쥐에서 분리된 담관 섬유모세포를 배양하고, 각각의 실험군에 간흡충 분비배설 물질(Cs excretory-secretory product, ESP)을 첨가하여 배양하였다. 배양된 섬유모세포의 미세구조 변화와 세포 표면에 존재하는 sialic acid 및 actin의 분포를 전자현미경으로 관찰하여, 간흡충 감염에 따른 섬유모세포의 변화 및 간흡충 분비배설 물질의 자극에 따른 섬유모세포의 변화를 관찰하여 흰쥐의 담관 섬유모세포와 간흡충 감염과의 연관성을 알아보고자 하였다. 정상 흰쥐 담관에서 분리한 섬유모세포(G1)에 비하여 간흡충에 감염된 흰쥐 담관에서 분리한 섬유모세포(G2)와 간흡충 분비배설 물질을 첨가하여 배양한 섬유모세포(G1-1, G2-1)의 증식속도가 느린 것이 확인되었다. 세포질돌기의 수는 간흡충에 감염된 흰쥐의 담관으로부터 분리된 섬유모세포(G2)에서 가장 많은 수가 관찰되었고, 배양배지에 분비배설 물질을 첨가하면 정상 담관의 섬유모세포에서도 세포질돌기가 증가하였다. 따라서 간흡충 대사물질은 섬유모세포의 세포질돌기형성을 촉진시키는 것으로 생각된다. 간흡충에 감염된 흰쥐 담관에서 분리한 섬유모세포(G2)의 소포체는 정상 담관에서 분리된 섬유모세포(G1)의 것에 비하여 감소하는 양상을 나타내었고, 여기에 분비배설 물질을 첨가하면 섬유모세포의 소포체가 증가하는 것이 관찰되었다. 그리고 세포표면에 분비되는 sialic acid는 주로 세포질의 소포낭 주변에서 관찰되었으며, 정상 섬유모세포(G1, G1-1)보다 감염된 섬유모세포(G2, G2-1)에서 증가하였다. Actin은 세포표면과 세포질돌기에서 주로 관찰되었으며, 정상 섬유모세포(G1, G1-1)보다 감염된 섬유모세포(G2, G2-1)에서 반응이 증가하였고, 간흡충 분비배설 물질을 첨가하면 G1-1은 반응이 증가하고, G2-1은 반응이 감소하는 것이 관찰되었다. 이상의 결과로 간흡충에 감염된 흰쥐 담관의 섬유모세포는 세포질돌기들이 매우 발달하며, actin단백과 sialic acid가 증가하여 세포변형을 초래하게 된다. 또한 간흡충 감염으로 손상된 담관의 섬유모세포로 구성된 결합조직은 정상으로 회복되지 않으며, 세포질 부피 및 세포질돌기의 증가는 이루어지지만 간흡충 대사물질의 영향으로 섬유모세포의 분열 및 성장 속도가 억제되는 것으로 확인되었다. 이 결과 간흡충 감염으로 손상된 숙주의 담관 결합조직과 섬유모세포들은 간흡충 대사물질에 의하여 변형을 일으키고, 세포 활성 및 증식이 Clonorchis sinensis is the most important widely distributed parasite of the human bile duct in East Asia and the most prevalent parasitic helminth in Korea. The prevalence rate of human clonorchiasis has remained at about 2.9% in Korea. C. sinensis induces dilatation of the duct, hyperplasia of the mucosa, metaplasia or neoplasia of the mucosal epithelium, periductal inflammation and fibrosis, and thickening of the ductal wall. Fibroblast are the most common cells in connective tissue and are responsible for the synthesis of extracellular matrix components. The fibrosis associated with chronic inflammation and injury may also contribute to cholangiocarcinoma pathogenesis, particularly through an increase in extracellular matrix components, which participate in the regulation of bile duct differentiation during development. In this study, ultrastructural changes, the distribution of lectin receptors and actin protein in cultured SD rat bile duct fibroblast after infection of C. sinensis were observed. Experimental group had been divided into four groups: normal bile duct fibroblast cultured in basal media (G1); C. sinensis infected bile duct fibroblast cultured in basal media (G2); normal bile duct fibroblast cultured in basal media containing excretory-secretory product (ESP) (G1-1); C. sinensis infected bile duct fibroblast cultured in basal media containing ESP (G2-1). Overall, once a host is infected by C. sinensis, it affects the host to the extent that sialic acid of ductal fibroblast is increased. Number of cytoplasmic process of SD rat bile duct fibroblast was increased. Actin protein and sialic acid were located in cell surface. Fibroblast induced by C. sinensis was not recovered to normal fibroblast. The cytoplasm bulk and cytoplasmic process were increased whereas the growth rate of the fibroblast of infected SD rat was reduced rather than that of normal fibroblast. In result, it inhibits fibroblast proliferation and increases actin protein on fibroblast cytoplasm, and so causes fibroblast metamorphosis and cellular mutation.