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재료 분석에서 전자 에너지 손실 스펙트럼 (EELS)의 원리 및 응용 연구
윤상원,김규현,안재평,박종구,Yoon, Sang-Won,Kim, Kyou-Hyun,Ahn, Jae-Pyoung,Park, Jong-Ku 한국분말야금학회 2007 한국분말재료학회지 (KPMI) Vol.14 No.3
본 고에서는 최근 재료분석에 활발히 응용되고 있는 EELS 분석장비의 원리와 응용 분야 등에 대해 검토하였다. EELS를 이용하여 수행할 수 있는 주요 응용분야로는 원소의 정성 및 정량분석, 원소 및 화학 맴핑, 화학물의 결함구조를 알 수 있는 전자구조(DOS)에 대한 힌트 등이 있으며, 점차 재료의 근본 적인 성질을 추출할 수 강력한 분석기가 되고 있다. 또한 원소를 분석하고 맹핑하는데 걸리는 시간이 수초에서 수분 이하의 시간으로 매우 짧아 전자빔에 의한 재료의 손상을 최소화시킬 수 있는 장점을 갖고 있다. 특히 나노미터 영역의 분말의 경우 원소의 분포가 불균일하고 전자빔에 의하여 쉽게 변형되는 재료 분석에 매우 유용하다. 향후 TEM의 발달과 함께 EELS는 국부적인 영역에서 가장 다양하고 유용한 정보를 추출할 수 있는 분석기로 자리매김할 것으로 기대된다. An electron energy loss spectroscopy (EELS) instrument attached on transmission electron microscopy (TEM) becomes a powerful and analytical tool for extracting the noble information of materials using the enhancement of TEM images, elemental analysis, elemental or chemical mapping images, electron energy loss near edge structure (ELNES), and extended energy-loss fine structure (EXELFS). In this review, the principle and applications of EELS which is widely used in material, life, and electronic sciences were introduced.
윤상원,최재철 대한의사협회 2019 대한의사협회지 Vol.62 No.1
Tuberculosis (TB) remains the world’s leading cause of death from a single infectious disease. In addition, the incidence of TB is high in South Korea. Effective TB control requires early diagnosis and initiation of appropriate treatment. Therefore, it is very important for clinicians to understand evidence-based practical recommendations and to be familiar with up-to-date treatment regimens. In this review, we first describe anti-TB drugs, including new drugs. Secondly, we discuss the treatment of drug-susceptible TB. Finally, we present treatment strategies for drug-resistant TB, which is divided into isoniazid-resistant TB, rifampin-resistant TB, and multi-drug resistant TB. For the treatment of drug-susceptible TB, we recommend 2 months of 4 drugs (isoniazid, rifampin, ethambutol, and pyrazinamide) followed by 4 months of 2 drugs (isoniazid and rifampin). For the treatment of isoniazidresistant TB, we recommend 6 to 9 months of 4 drugs (rifampin, ethambutol, pyrazinamide, and levofloxacin or moxifloxacin). For the treatment of multi-drug resistant TB (MDR-TB), we recommend a minimum of 5 secondary drugs, including an injectable agent and quinolone. Although the World Health Organization recommended a shorter MDR-TB regimen in 2016, the Korean guidelines for tuberculosis have not yet accepted the shorter regimen. The treatment regimen of TB differs depending on the drug resistance pattern. Therefore, it is important to treat TB properly after confirming the drug resistance pattern. In addition, as new drugs are developed, new treatment guidelines for MDR-TB should be developed that are appropriate for circumstances in Korea.
윤상원 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.5
This study presents a new design of an electromagnetic energy harvester integrated with a soft magnetic material. The harvester design optimizes the magnetic material characteristics and the size of a rectangular permanent magnet. The design employs a complete magnetic circuit made of (1) a thin-film soft magnetic material that facilitates a flexible but highly (magnetically) permeable beam and (2) an optimally-sized magnet that maximizes the harvester performance. The design is demonstrated to reduce magnetic flux leakage, and thus considerably enhances both magnetic flux density (B) and its change by time (dB/dt), which both influence harvester performance. The improvement in harvester performances strongly depends on critical design parameters, especially, the magnet size and characteristics of magnetic materials, including permeability, stiffness, and thickness. The analyses conclude that recently-introduced nanomaterials (having ultrahigh magnetic permeability) can potentially innovate harvester performances. However, the performance may be degraded without design optimization. Once optimized, the integrated nanomaterials facilitate a significant improvement compared with a conventional design without integrated magnetic materials.
윤상원 한국정신과학학회 1999 한국정신과학회 학술대회 논문집 Vol.11 No.-
In order to activate the human brain(the powers latent within one), We developed a expenmental apparatus using Micro-vibration motors with α-wave level. It is analyzed by the statistical method that the effects of brain activation through scientific experimental results(brain wave, Infra-red imaging system, a questionnaire, reading-concentration experimentaltion) These results show the brain activation is not only significant but also reliabie statistically. This methodology is expected to contribute much to brain development together light and sound stimulus
윤상원,임승철,노성우,유종윤,하상배,Yoon, Sang Won,Rhim, Seung Chul,Roh, Sung Woo,Yu, Jong Youn,Ha, Sang Bae 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.4
Objective : To investigate objectively the postoperative improvement of gait disturbance in patients with cervical myelopathy through a gait analysis. Patients and Methods : Ten patients who underwent cervical decompression and fusion for cervical myelopathy caused by spondylosis, OPLL, or concomitant hypertrophy of ligamentum flavum were studied. Preoperatively, gait disturbance was present in all patients. The patients were evaluated by gait analysis using three dimensional motion analyzer to collect data of linear and kinematic parameters before surgery, 1 week and 3 months after surgery. Statistical analysis of the related pre-and post-operative data were performed. Results : In the linear parameters, average value of cadence, walking speed, stride length, step time, width and double support were increased postoperatively compare to preoperative value. In the kinematic parameters, average value of knee flexion during initial swing phase, plantar flexion of ankle and range of motion of hip joint were increased as well. These differences were statistically significant(p<0.05). Conclusion : This study suggests that gait analysis can be used as a method of quantitative analysis of postoperative gait improvement in patients with cervical myelopathy.