Effect of 3 - Aminobezamide on DNA Fragmentation Induced by Mitomycin C and Cytotoxic Lymphocyte

손정희,김영상,민들레,황대연 한국유전학회 1995 Genes & Genomics Vol.17 No.4

The poly (ADP-ribose) polymerase (pADPRp) was found to be involved in DNA repair, DNA replication and recombination etc. There were several reports suggesting the involvement of pADPRp in apoptosis process, but only in limited conditions. To study the function of pADPRp in the apoptosis induced by alkylating agent or by cytotoxic lymphocyte, various cells were treated with a pADPRp in the apoptosis induced by alkylating agent or by cytotoxic lymphocyte, various cells were treated with a pADPRp inhibitor, 3-aminobenzamide (3-AB), as well as mitomycin C (MMC) or cytotoxic lymphocyte. P815 mouse mastocytoma, A20 B cell lymphoma and HL-60 human promyelocytic cells treated with MMC or cytotoxic lymphocyte showed DNA ladder of multiple nucleosomal sizes. DNA fragmentation induced by MMC was gradually decreased by increasing dose of 3-AB in HL-60 cells, but not in other cells. This result suggest that apoptosis signaling pathway in HL-60 cell, which is deficient in p53 expression, involves pADPRp, but not in others. The DNA fragmentation induced by cytotoxic lymphocyte was not affected by 3-AB in all the three cell types, suggesting that the apoptosis signaling pathway by MMC is different from that by cytotoxic lymphocyte.

獻仙桃에 대한 考察 : 文獻을 中心으로

孫貞姬 한국무용연구회 1982 한국무용연구 Vol.1 No.-

The purpose of this study is to establish a clear concept on “Dong-Ak-Jung-Jae” (Chinese music-styled court singing and dancing) by comparatively analyzing contents, forms and various elements of “HEON SUN DO” which belongs to “Dang-Ak-Jung-Jae” among traditional court dances, and also to examine the possibility of the revival of old court singing and dancing which has been handed down only through document, by resorting “Heon Sun Do” to it’s original form through reviewing of it’s general forms and characteristics. In the changing process and structure of “Goong-Joong-Jung-Jae” (court singing and dancing), it is considered that each work of court singing and dancing has a racial character rising above an unique expression of feeling, and oriental thought of philosophy of “Eum Yang Five Elements” dwells in the ceremonial procedures and framework itself, and that form of dance is characterized by it’s courtesy, slow tempo and it’s meaningful, free use. The “Goong-Joong- Jung-Jae” is classified into two parts of “Hyang-Ak-Jung-Jae” (Korean traditional music style) and “Dang-Ak-Jung-Jae” (Chinese music-styled singing and dancing). The contents of “Heon-Sun-Do”, a typical dance of “Dang-Ak-Jung-Jae are that Wang-Mo comes down from the fairy land to present the fairy land’s pcaches to the King to pray for long living of the King. In the form of dancing motion, the first KuHo of the ceremony is announced by 2 Bongjuk- Kanja (ceremony processors who are playing a role of guide for dancing), then stands facing inward each other. Then, 1 Kisaeng (youth or juniors are preferrable) gives fairy land's peach tray to Wang-Mo, and Wang-Mo faces westward, singing words of song in Chinese characters. Thus, all procedures for ceremony to announce the beginning of dance are just finished. Now, they start dancing in full scale. First, all of dancers return to their original form, performing various dances, such as “Sasu-Mu”, “SuboRock-Mu”, “Hyupsu-Mu”, etc, and singing words of other songs between some intervals of dancing. After that, facing forward, Bongjuk-Kanja announce “after-KuHo” by saluting that the dancing was finished, and all of dancers move backward. In the comparative analysis of music journal “Koryo-Sa-Ak-Chi”, “Ak-Hak-Kwe-Bom” and “Goong-Joong-Jung-Jae-Mu-Do-Hol-Gi” (at the end of Yi Dynasty), some music used for the subject dancing is found to be of the same name of melody (or tune) and some others are found to be of different name of tune. However, the details on the forms and contents of music are unknown, because it was not shown in old documents. Therefore, the forms and contents of music used depend upon common name and pen name which were established by the National Classical Music Institute. Moreover, “KuHo-Chio” and “Chio” of “Koryo-Sa-Ak-Chi” were divided into “before- KuHo" and “after-KuHo” since “Music Standard”, and the “Jakkan-Ja” announced it in such way, and sang it in the abridged form of contents. “Won-Mu” (dancing team consists of 3 dancers), 1 “Wang-Mo” (Sun-Mo shown in “Goong-Joong-Jung-Jae-Mu-Do-Hol-Gi”), 2 “Hyup- Mu”, and “Bongwi-Eui” consists of 18 members. Moreover, we can easily understand that costumes and ceremonial things for them are found to be the same one as in other “Jung-Jae” in most cases. However, many changes for dancing motion and forms had been made due to the contemporary performance situation, especially in it’s contents. Moreover, we are unable to compare such changes in detail because there are not records in documents for it. As commented above, it is well concluded that, some changes has been made for “Heon Sun Do” during the period from “Koryo-Dynasty” to “Chosun-Dynasty”, including changing of names, singing it in the abridged form of song words and changing of music, especially in con¬tents and forms. However, it is considered that “Heon-Sun-Do” is a typical “Dong-Ak-Jung-Jae” which preserves it’s original form without being much changed both in it’s contents and forms.

拇指尺側種子骨의 出現과 齒牙發育과의 關係

孫政姬,成在鉉 慶北大學校 齒科大學 1984 慶北齒大論文集 Vol.1 No.1

The relationship between tooth mineralization and early radiographic evidence of the adductor sesamoid was studied with hand-wrist radiographs and Orthopantomographs which were taken in 193 boys and 126 girls aged 9 to 14 years. In addition to this, it was investigated the distribution of the ossification stages of the adductor sesamoid and the age at which the ossification of the adductor sesamoid occurred. The results were as follows: The distribution of the ossification stages of the adductor sesamoid was consistent with the acknowledged sex difference in general developmental progress and the rate of progressive ossification in girls was also found to be faster than that in boys. The ossification of the adductor sesamoid of the thumb occurred at 13-years-0-month in boys and 11-years-2-months in girls. Prior to the stage E of tooth mineralization of upper and lower canines, lower lst and 2nd premolars and lower 2nd molars in boys and girls, there was no evidence of the adductor esamoid ossification. The ossification of the adductor sesamoid was closely related to the stage G of tooth meralization of the mandibular 2nd molar in boys and the stage F of the mandibular 2nd mo??r in girls.

[우리 협동조합을 소개합니다] 손에 손잡고 가는 세상

손정희 한국협동조합연구소 2013 협동조합네트워크 Vol.- No.62

세치제 짜는 방법에 따른 보육교사의 어린이용 세치제 사용량 조사

손정희,박일순,마득상 韓國學校保健學會 2009 韓國學校保健學會誌 Vol.22 No.1

Purpose: The purpose of this study was to examine the relationship between the toothpaste squeezing methods and the amount of toothpaste that the daycare teachers apply for the children in order to prevent the overuse of fluoride-containing toothpaste among children, and to understand their educational experiences on oral health and their awareness of the right amount of toothpaste used. Methods: The subjects in this study were 87 teachers at 16 different daycare centers in the city of Sokcho, Gangwon Province. They were interviewed to find out whether they had ever received oral health education and whether they were cognizant of the right amount of toothpaste to be used. And a transverse technique and a pea-sized squeezing technique were selected to look for connections between their toothpaste squeezing methods and the amount of toothpaste used by them. Results: 89.7 percent of the daycare teachers investigated taught to preschoolers how to do toothbrushing after they took meals and had a snack. 36.8 percent of the daycare teachers had children squeeze toothpaste on their own. The amount of toothpaste applied by the daycare teachers at a time was 0.58g. When they utilized two other squeezing methods, transverse technique and pea-sized squeezing technique, they used each 0.38g (p<0.005) and 0.38g(p=0.405) of toothpaste. Conclusion: To prevent children from being overly exposed to fluoride-containing toothpaste, daycare teachers should learn about the right amount of toothpaste to be used when oral health education is provided, and the transverse technique should be recommended to ensure the use of the proper amount of toothpaste.

「靑邱野談」所載 風水設話 硏究

손정희 慶星大學校 附設 韓國學 硏究所 1993 文化傳統論集 Vol.1 No.-

山神信仰硏究 : 文獻說話를 中心으로

손정희 부산대학교 한국민족문화연구소 2000 한국민족문화 Vol.16 No.-

The mountain god is the most intimate with our Korean people regardless of religion. Although the faith or the thought is destined by the religion and the current, we Korean have believed the god of mountain. For the first time, the mountain goddess was respected as the Holy mother of the Progenitor. It shows us that the faith of the mountain god was the way for strengthening the sovereign power by uniting the faith of mountain god with the faith of the Holy mother. When the paternal rights was strengthened fort Confucianism, The Goddess of the mountain married the God of mountain. So she transferred her role to men naturally. In those days, the God of Jiri Mountain have been woman although she have had a lot of characters. It gives us the evidence the early god of the mountain was the woman. Sung Gol General who married the Goddess of Buso mountain confined the sacredness of the Corea Dynasty's lineage as the Father of the first Emperor, Wang Gun and the Bupu Buddhist priest who married the Goddess of Jiri Mountain endowed with motive that Buddhism, the faith of mountain god and Shamanism were united as the Father of Shaman. There were the mountain grid seemed like animals. While the tiger and the bear have been the intimate animals to us and they were agents of the mountain god as we know, the fox and the crow have been considered as unlucky or wicked animals. So I was surprised that there had been the mountain god seemed like the fox or the crow. Therefore there are a tot of differences between today's thought about animals and old one. I could study we ancient Korean people's thought of the mountain god with the legendary literature about the mountain god. But it is hard to research the faith of the mountain god that is handed by word the mouth among the people. I'll leave the today's thought of the mountain god based on the literature handed by word of mouth.

智異山 山神에 관하여

손정희 문창어문학회 2000 문창어문논집 Vol.37 No.-

There have been a lot of going first studies about the God of JiRi mountain. Most of the studies have said that the Holy Mother of JiRi Mountain have been identified with the God of JiRi mountain. But it is almost impossible to identify the Holy Mother of the Holy Mother temple(Seong Mo Sa) with the Goddess of JiRi mountain. Because we can not study exact period(time) when the Holy Mother Temple(Seong Mo Sa)had established. Existing studies explain The Holy Mother of JiRi mountain with three types greatly. First, She may be the Queen Wisuk, mother of the first King of Goryeo. Second, She may be Madame Maya, Buddha's mother. And third, she may be the Goddess of mountain who was married with Beobu Buddhist priest. The first assumption that The Holy Mother may be Queen Wisuk is the most reasonable. Because the Holy Mother temple(Seong Mo Sa) had been bulit for taking advantage of the religion of the god of mountain, which had been popular beliefs, at the time to promote orthodox and authority of Goryeo Dynasty when The first King, Wangkeon had established Goryeo Dynasty. Most scholar have negative opinions about second assumption that the Holy mother is Madame Maya because it is the most unfounded. But the reason that this assumpion is widespread is that so many people had believed in Buddhism in the age of the Goryeo and Buddhism and the belief of the God of mountain had never had any conflicts among the people, so these facts let us think that the Holy Mother is may be Madame Maya. And especially, at that time, people had called the God of JiRi mountain, the Grandmother Mayago or the Grandmother Mago. Because of such a similarty of pronunciation, we can think that the Holy Mother may be Madame Maya. The third assumption that the Holy Mother is the Goddess of Mountain who was married with Beopu Buddhist priest, is a kind of traditional folk story. people made that The Holy Mother was mother and the noble Buddhist priest was father, and then they made the daughters who were bone between the two be shamans of all parts of country. So they were inseparably bound up each other. These facts show our religious reality of popular beliefs. But these three assumptions only disclose the Holy Mother's identity, and we can not think that it disclose the God of Mountain's identity. It may not be unreasonable to think The Grandmother, Mago as a Goddess of Motain who is the object of popular belief, has known by hearsay for God of JiRi Mountain since old time. Because the grandmother's super characteristics were given in a lot of traditional tales about the god of Jiri Mountain, and in the tale, said that Beobu Buddhist priest was Banya Buddhist priest, her identity was disclosed with the Grandmother Mago. I think that the gradmother Mago who was reported widely in traditional tales is the most suitable to the God of JiRi Mountain. Because the God of JiRi Mountain can not be limited by religious or histories while the Holy Mother of JiRi Mountain is kinds of limited historical characters like Queen Wisuk or Madame Maya.

<여성미국인>은 미국소설인가?: 미국소설의 발생과 대서양횡단 관점의 재고

손정희 미국소설학회 2014 미국소설 Vol.21 No.3

정자기장과 맥동전자기장이 MC3T3-E1 세포의 ALP 및 ANA 활성동에 미치는 영향

손정희 慶北大學校 齒科大學 1995 慶北齒大論文集 Vol.12 No.2

정자기장과 맥동전자기장이 배양 조골세포에 미치는 영향을 알아보고자 MC3T3-E1세포를 각 자기장하에서 배양하여 ALP활성도와 DNA의 합성능을 평가한 결과 다음과 같은 결과를 얻었다. . 정자기장을 가한 군에서 자석을 1,2,3개 가한 군 (51∼114.8mT)에서 대조군에 비하여 ALP의 유의성 있는 증가가 나타났으며 (P<0.05), 자석을 4개 5개 가한 군 (150mT)에서는 대조군에 비하여 ALP활성도에 차이가 나타나지 않았다. . 맥동성 전자기장에서는 대조군에 비하여 ALP활성도에 유의한 차이가 나타나지 않았다. . DNA 합성능은 정자기장과 맥동성 전자기장을 가한군 모두 대조군에 비하여 유의한 차이가 나타나지 않았다. 이상의 결과 정자기장에 의한 교정력은 골세포의 대사과정에 변화를 줄 수 있으므로, 치아이동에 어떠한 영향을 줄 수 있을 것으로 사료된다. The purpose of this study was to evaluate the effects of magnetic field on cellular activity of MC3T3-E1 cells. The cellular activity was monitored by alkaline phosphatase and DNA synthetic activity in control, static magnetic field and pulsed electromagnetic field groups. A static magnetic field was applied to the cell by placing one, two, three,four, and five samarium-cobalt magnets above and below each cell plate for 24 hours per day. A pulsed electromagnetic field with a frequency of 100 herz was applied for 10 hours per day. After 10 days of magnetic field exposure, there were increase of alkaline phosphatase activity in static magnetic field groups consisted of one, two and three magnetic groups. Alkaline phosphatase activities were not significantly increased in four and five magnetic groups. Application of pulsed electromagnetic field did not result in significant increased in alkaline phosphatase activity compared to control. DNA synthetic activity in both static and pulsed eletromagnetic field group were ont significantly different from that in control group. The result of this study suggest that magnetic field could have effect on the metabolism of bone cells related to the cellular metabolic process.