상한논에 대한 정신의학적 연구

문상태(Sang Tae Moon),신용현(Yong Hyun Shin),구병수(Byung Su Gu) 대한한방신경정신과학회 2000 동의신경정신과학회지 Vol.11 No.1

This study was aimed to get the course which is caused by Neuropsychiatric symptoms in Sang-Han. Therefore this study is based on 『Euhak-Ipmun. Sang-Han』(『醫學入門.傷寒』) classfied mainly by symptoms. The results were summerized as follows: 1. Neuropsychiatric symptoms in 『Euhak-Ipmun. Sang-Han』(『醫學入門. 傷寒』) are explained as Pal-Gang(八綱), which shows those are settled down to a systematic oriental medical theory. 2. Pal-Bup (八法) used in the cure of symptomatische psychose in 『Euhak-Ipmun. Sang-Han』(『醫學入門. 傷寒』), which is intended to boost the effect of cure, choosing the respondent cure method about various causes. 3. Pal-Gang(八綱) and Pal-Bup(八法) in『Euhak-Ipmun. Sang-Han』(『醫學入門·傷寒』) are improved by Lee-Chun(李 ) who added Jang-gi(張機)`s Sang Han theory and new medical thought in the ages of Geum. Won. 4. Lee-Chun(李 ) believed that Neuropsychiatric symptoms which appeared in Sang Hang is caused by the Unbalance(不平). So he wanted to reach harmony of Jeong(精), QI(氣), Shin(神), Hyul(血) after improving the status of Unbalance(『不平』) toward the status of Balance(平).

中樞性 交感神經 效能藥의 體溫調節에 미치는 影響

신인철,서대규,이승도 漢陽大學校 環境科學硏究所 1989 環境科學論文集 Vol.10 No.-

生體機能의 均衡을 維持하는데는 體溫調節이 重要한 役割을 하며 體溫은 體內의 體溫調節機構의 作用으로 體熱의 生産과 發散間의 均衡을 이루어 一定한 節圍로 保存되고 있다. 中樞性 體溫調節에는 brain monoamines의 濃度가 重要한 役割을 하며 中樞性 交感神經效能藥인 methamphetamine은 brain monoamines 溫度를 上昇케 하고 methyldopa는 이를 下降케 한다고 알려져있고 ethanol은 noradrenaline 또는 5-hydroxytryptamine을 通하여 體溫下降을 招來케 한다고 알려져 있으므로 ethanol誘發 低體溫症에 對한 methamphetamine 및 methyldopa의 作用을 생쥐에서 實驗的으로 比較檢討하여 다음과 같은 結果를 얻을 수 있었다. Ethanol(3g/kg)의 腹腔內住射는 顯著한 體溫下降(低體溫症)을 招來하였으며 이 作用은 注射後 60分頃부터 發現되어 實驗終了時까지 持續되었다. Methamphetamine(1,2 및 4mg/kg. 腹腔內注射)은 用量에 比例하여 體溫을 上昇케 하였으나 methyldopa(1,2 및 4mg/kg. 腹腔內注射)는 對照的으로 體溫을 下降케 하였고 이 作用은 用量增加에 따라 減弱되었다. Ethanol 低體溫症에 對해서는 methamphetamine을 抗拮的으로 作用하였으나 methyldopa(1 및 2mg/kg)는 이에 影響을 미치지 않았고 比較的 大量(4mg/kg)은 ethanol 低體溫症에 拮抗的으로 作用하였다. Ethanol 前處置는 methamphetamine에 依한 體溫上昇作用을 抑制하였고 比較的 大量(4mg/kg)의 methyldopa에 依한 體溫下降作用을 增强하였다. Brain monoamines among other brain neurotransmitters play a role in thermoregulation. Methamphetamine causes increased brain monoamine levels, while the converse is true for methyldopa. The effects of drugs that may influence braine monoamines, d-methylamphetamine(1,2, and 4mg/kg, i.p.) and α-methyldopa(1,2, and 4mg/kg, i.p.) on rectal temperature and on ethanol(3g/kg, i.p.) induced hypothermia have been investigated in mice. Ethanol causes a significant reduction in rectal temperature which lasted from the time interval starting at 60min to end of the experiment. Methamphetaminecaused a significant hyperthermia in a dose-dependent manner, but methyldopa induced hypothermia, which decreased with increases in dose. Methamphetamine antagonized the hypothermic effect of ethanol but methyldopa did not affect it. Methyldopa in high doses(4mg/kg), however, reversed ethanol-induced hypothermia. Ethanol pretreatment significantly potentiated the hypothermic effet of methyldopa(4mg/kg) and it prevented methamphetamine-induced hyperthermia.

花粉形態 및 유리 아미노산의 성분에 의한 소나무속의 分類

辛昌男,柳柄泰,柳成浩 충남대학교 자연과학연구소 1983 忠南科學硏究誌 Vol.10 No.2

3 species of Pinus in Korea, P. densiflora, P. rigida, P. koraiensis, were classified by polynological studies and TLC analysis of the free amino acids in pollen. The shapes of pollen grain are similar in 3 species. P. densiflora showed some differences in the size of pollen grain and in the number, the pattern, the angle of attachment and the size of air bladder with other 2 species (p<0.05). The cell wall thickness and the type of germ furrow surface of P. koraiensis are different from those of P. densiflora and P. rigida (p<0.05). Serine, glutamic acid, alanine, valine and histidine were detected in the pollen of P.densiflora and P. rigida, but not in that of P. koraiensis.

증기발생기 전열관 검사를 위한 차동형 원격장와전류 탐촉자 설계

신영길,신상호,정태언 국립7개대학공동논문집간행위원회 2001 공업기술연구 Vol.1 No.-

As steam generator (SG) tubes have aged, new and subtle flaws have appeared. Most them start growing from outside the tubes. To find outer diameter defects more easily, the author had shown that the remote field eddy current (RFEC) technique, which had shown equal sensitivity to inner diameter (ID) and outer diameter (OD) defects, is feasible for the inspection of SG tubes. Based on the results obtained in that study, this paper designed a differential RFEC probe and studied the characteristics of differential RFEC signal. Finite element modeling studies show that the differential signal still has the equal sensitivity to ID and OD defects and at the same time it is possible to distinguish one from the other. Also noticed is that there is few degrees of signal rotation but sensitive changes in signal length when the depth of small defect varies. If the volume of defect is large, the changing rate of signal length is higher than that of defect size variation. The characteristics of signal show that the proposed differential RFEC technique can be a good alternative for the initial inspection of SG tubes.

질량의 최적 배치에 의한 구조물 진동 감소 연구

申龜秀,李祺形,朴泰圓,鄭寅聖 全北大學校 1996 論文集 Vol.42 No.-

In this paper, a theoretical optimization approach is presented in order to consider natural frequencies for vibration transmitted to the fuselage. Also, this paper describes methods for reduction of structural vibration by the optimal placement of masses for formal mathematical optomization techniques. An optimization procedure is developed which employs the tuning masses and corresponding locations as design valiables which are systematically changed to achieve low values of shear without a large mass penalty. Three optimazation strategies are developed and tested. The first is based on minimizing the modal shaping parameter which indirectly reduce the modal shear amplitudes corresponding to each harmonic of airload. The second strategy reduces these amplitudes directly and the third strategy reduces the shear as a function of time during a revolution of the blade.

초등학생의 Molar Incisor Hypomineralization 유병률과 제1대구치 치아우식증 및 수복상태 조사

신종현,안울진,김신,정태성 大韓小兒齒科學會 2010 大韓小兒齒科學會誌 Vol.37 No.2

Molar Incisor Hypomineralization(MIH) have recently gained intensive research interests and various clinical trials. Most prevalence, etiology, treatment studies in MIH were carried out in the European countries, and data from the Korean were seldom. This study aimed to investigate the prevalence of MIH and the status of dental caries and treatment on the first permanent molars in primary school children. For this study, 1.344 primary school students in Busan and Ulsan cities were examined directly the permanent incisors and first molars. The results of the survey were as follows: 81 MIH cases were identified among 1.344 cases. The prevalence of MIH in this group of children was 6.0%. Children with MIH showed a significantly higher DMFT value for permanent teeth than children without MIH. The mean number of decayed, missed, and filled in 1st permanent molars(DMFT index) was 1.17. The rate of children with restoration on 1st permanent molar was 13.6% and the sequence of restoration materials was as follows: composite resin, amalgam, gold inlay. Molar Incisor Hypomineralization(MIH)에 관하여 최근 많은 연구적 관심이 집중되고 여러 임상적 대처방법들이 제시되고 있다. 이미 세계적으로는 MIH의 빈도, 병인, 치료 등에 관한 많은 연구보고가 있었으나, 우리나라에서는 이에 대한 관심이 아직 미미한 것으로 사료된다. 본 연구는 초등학생의 MIH 유병률과 제1대구치 우식 및 치료 실태에 대하여 조사할 목적으로 시도되었다. 부산 및 울산광역시에 거주하는 1,344명의 초등학생을 대상으로, 상하 제1대구치와 전치부를 직접 시진하여, MIH 유병률, 제1대구치 우식경험지수와 치료 상태를 조사하여 다음과 같은 결과를 얻었다. 총 1,344명 의 조사 대상 중 81명에서 MIH가 나타나, 유병률은 6.0%를 보였으며, MIH에 이환왼 어린이의 제1대구치 우식경험지수는 비이환군에 비해 통계적으로 유의하게 높았다(P<0.05) 한편, 제1대구치 우식경험지수는 1.17개로 나타났다. 조사 대상 제1대구치의 13.6%가 수복되어 있었고, 수복재 별로는 복합 레진, 아말감, gold inlay의 순이었다.

Fluoranthene 독성에 기인하는 비정상적 어류행동의 신경생화학적 분석

신성우,조현덕,전태수,김정상,이성규,고성철 한국환경독성학회 2003 환경독성보건학회지 Vol.18 No.2

Fluoranthene, a common polycyclicaromatic hydrocarbon (PAH), exhibits phototoxicity which may affect aquatic organisms, The eventual goal of this study is to develop a biomarker of Japanese medaka (Oryzias iatipes) used in monitoring hazardous chemicals in the ecosystem. In this study we investigated neural toxicity of fluoranthene in Japanese medaka (Oryzias latipes) along with comparative analysis of corresponding behavioral responses. The untreated individuals showed normal behavioral characteristics (i.e' smooth and linear movements). The treated fish, however, showed stopping and abrupt change of orientation (100 ppb), and severely reduced locomotive activity and enhanced surfacing activity (1,000ppb). Treatment of the medaka fish with fluoranthene caused a significant suppression of acetylcholine esterase (AChE) activities in the body portion but not in the head portion. When fish were exposed to 1,000pph of fluoranthene for 24hr, the body AChE activities decreased from 126.±31.89 (nmoles substrate hydrolyzed per min per mg protein) 10 49.51 ± 11.99. Expressions of tyrosine hydroxylase (TH) protein in the different organs from both head and body portions were comparatively analyzed using an immunohistochemical technique. Five organs of the medaka fish showing a strong TH protein expression were the olfactory bulb, hypothalamus, optic lobe, pons and myelencephalon regions. This study provides molecular and neurobehavioral bases of a biomonitoring system for toxic chemicals using fish as a model organism.

급성 심근경색 초기에 도플러 심초음파를 이용한 좌심실 이완기 기능의 평가

신원용,김주성,김철현,이광희,최태명,현민수,김성구,권영주 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Background : Congestive heart failure after acute myocardial infarction relate to left ventricular systolic sysfunction. Also, left ventricular diastolic function contribute to heart failure. The aims of this study were, firstly to characterize left ventricular diastolic function by transmitral flow velocity, and secondly to study the significance of Doppler measurements in relation to the development of heart failure in the early phase of myocardial infarction. Method : Pulsed Doppler echocardiography of transmitral flow was assessed in 34 patients with acute myocardial infarction. According to the Doppler transmitral flwo velocity profile, the study patients were assigned to the three groups: normal filling pattern (DT > 140ms, IVRT < 100ms), relaxation abnormality (DT > 140ms, IVRT ≥ 100ms), pseudonormal or restrictive pattern (DT ≤ 140ms). Also, on the basis of the presence of heart failure during first week of hospitalization, the patients were divided into two groups: patients with no sign of heart failure (Killip class Ⅰ) and heart failure (Killip class Ⅱ-Ⅳ). Results : Of the 34 patients studied, 10(29%) were normal filling pattern, 17(50%) abnormal relaxation and 7(21%) were restrictive patterns. The left ventricular ejection fraction(EF, 40 ±6%) of restrictive pattern was significantly lower than that of normal filling pattern of abnormal relaxation(p < 0.01). And, the IVRT, DT, E/A and left ventricular EF were reduced in patients with heart failure(14 patients) compared to no sign of heart failure(20 patients)(p<0.05). Of the patients with heart failure, IVRT and left ventricular EF were reduced in patients with DT≤140 ms compared to DT> 140ms(p=0.001). Conclusion : Left ventricular diastolic dysfunction is present early after onset of symptoms of acute myocardial infarction. Assessment of left ventricular diastolic function complements measurements of systolic function in the evaluation of cardiac function. DT, IVRT, E/A and left ventricular EF are useful predictors for development of congestive heart failure following acute myocardial infarction.

수요자의 요구와 아파트 단위세대 평면계획의 상관관계에 관한 연구 : 용인지역을 대상으로

신중진,박성진,김명훈,김태엽 대한건축학회 2004 대한건축학회논문집 Vol.20 No.2

The purpose of this study is to define the correlation between consumer's needs appearing diversely in recent years and characteristics of apartment unit plan derived from categorizing composition forms of unit plan. The results of this study are as follows; ① The separation and connection of public zone have relation to use space economically with living room in the center. ② The opened space composition is reflected to an increase in size and openness of the living room. ③ The variability by the hierarchy change of space appears into the introduction of variable designs through light wall and family room. ④ The protection of privacy and communication have relation to the separation of master zone and conversion of inner room to family communication space. ⑤ The diversity and individualization of rooms appear into giving a special function to rooms increased by the extension of bay. ⑥ the extension and connection of service space are reflected to an increase in size of balcony and storage and the flexibility of utility space. ⑦ The recovery of emotionality has relation to the introduction of interior garden.

급성 뇌졸중 환자의 경동맥 죽상경화반 표면 불균일성과 뇌졸중 예후 인자 및 기능적 예후의 연관성 평가: 예비 보고

박영태, 이혜림, 여민주, 김지선, 이성현, 이상수, 신동익 충북대학교 의학연구소 2016 忠北醫大學術誌 Vol.26 No.2

본문참고