한국인 인슐린 비의존형 당뇨병 및 이차성 당뇨병 환자에서 글루코키나제 유전자 변이

남재현(Jae Hyun Nam),이현철(Hyun Chul Lee),김연의(Youn Euy Kim),권석호(Suk Ho Kwon),윤용석(Yong Suk Yoon),박석원(Suk Won Park),원영준(Young Jun Won),차봉수(Bong Su Cha),송영득(Young Duk Song),이은직(Eun Jig Lee),임승길(Sung Kil Lim) 대한내과학회 1998 대한내과학회지 Vol.54 No.6

N/A Objectives: Mutations in the glucokinase (GCK) gene are considered a possible cause of maturity-onset diabetes of the young. The purpose of this study was to evaluate the contribution of this gene to the development of non insulin dependent diabetes mellitus (NIDDM), gestational diabetes mellitus (GDM) and post-renal transplantation diabetes mellitus (PTDM). Method: Identification of GCK mutation was attempted on 39 NIDDM patients, 2 GDM patients and 58 selected renal allograft recipients with PTDM and 45 normal controls. The exons in the GCK gene were examined by polymerase chain reaction (PCR), followed by analysis of single-stranded DNA conformational polymorphism (SSCP). The abnormal bands were also confirmed by DNA sequencing analysis. The exons of affected family members were also investigated for mutations of the GCK gene. Results: Two of the 58 PTDM patients (3.4%) were found to have CKK mutations. One had the mutation on exon 5 and the other on intron 7. One control subject had the mutation on intmn 9. The mutation of exon 5 was identified as a substitution of CCT (proline) for CTT (leucine) at codon 164, which has not ever reported before. The family members of the PFDM patient with mutation of exon 5 were analyzed by PCR followed by SSCP, and two of them revealed the same mutation. The abnormal band on the SSCP analysis of exon 7 was identified as the insertion of base C/T at the 39th nucleotide in intron 7. Two family members of this patients also had same band on SSCP. The one mutation of 45 normal controls was CT located at the 8th nucleotide in intron 9, which was a common polymorphism. Conclusion: We found GCK mutations in subjects with PTDM and we speculate that these mutations may be one of the contributing cause of PTDM.

지능형 정속주행 제어시스템 개발

임영도,설재훈,한창훈,김승철,박종오,이준탁,방석원 東亞大學校 附設 情報通信硏究所 1998 情報通信硏究所論文誌 Vol.6 No.1

This paper describes an intelligent cruise control system for automobile. With the remarkable numericalincrease of automobiles on the roal, the optimized traffic flow control using the cruise control is one of the very important traffic problems to overcome the limitation of an existing road capacity. Based onthis idea that minimize the fuel cost and teh air pollution, and accept a driver's needs for driving, we have developed an intelligent cruise control system for vehicle. This proposed intelligent fuzzy cruise controller was successfully implemented using the fuzzy algorithm, the i80c196 μ-controller board and the throttle valve actuator. The field test results on an linear road was introduced.

K-WISC-Ⅲ를 이용한 ADHD 아동의 인지적 특성에 관한 연구

임목옥,오상우,백영석 圓光大學校 醫科學硏究所 2004 圓光醫科學 Vol.19 No.2

본딩 웨이퍼 검사를 위한 모델링 연구

임영환,양시은,장동영,안효석,홍석기 한국공작기계학회 2008 한국공작기계학회 춘계학술대회논문집 Vol.2008 No.-

본 논문에서는 레이저 빔 투과를 이용한 본딩 웨이퍼 검사 방법을 제안하고 검사 장치를 설계 구현하였다. 1064nm파장에서의 정상웨이퍼를 일정한 비율로 투과하였다. 본딩 불량으로 인한 웨이퍼의 기공은 두께에 따라 투과율이 현저하게 변화하여 기공 부분을 검출하였다. 이러한 기공은 두께의 변화가 있으며 광량의 변화하는 부분이 에어갭으로 인식 카메라로 쉽게 구분이 가능하였다.

Pulsed field gel electrophoresis(PFGE)를 이용한 Yersinia entirocolitica의 특성조사

임순영,윤석권 동덕여자대학교 생활과학연구소 2006 생활과학연구 Vol.11 No.-

Pulsed field gel electrophoresis(PFGE) was conducted compare the Not I digested genomic profile of one hundred Yersinia entirocolitica. This method was very efficient for subtyping pathogenic and non-pathogenic isolates of Yersinia entirocolitica. Generally, pulsotype was more closer to serotype than biotype. But pulsotype of 3/O:5 was more related to biotype than serotype. For epidemiological purpose, the comparison of relationship among biotype. serotype, RAPD(random amplitication of polymorphic DNA) and pulsotype of PFGE should be studied as powerful tools.

한국상장기업의 所有構造와 資本調達政策에 관한 연구

임석필,송영열 단국대학교 산업연구소 1997 산업연구 Vol.20 No.-

전전자 교환기에서의 과부하제어에 관한 연구

林錫鳩,張殷永,金元厚 한국항공대학교 1991 論文集 Vol.29 No.-

TDX-10 및 EWSD 기종의 과부하 제어방식을 검토한 후 프로세서 점유율 측면에서 성능이 향상된 제어방식을 3가지로 분류하여 제안하며, 각각을 가정된 모델에 따라 시뮬레이션을 수행하여 성능평가를 행하였다. 그 결과 TDX-10L방식을 제외한 제안한 방식은 과부하 상태에서도 시스템 설계용량인 90%의 프로세서 점유율로 유지함을 확인하였다. The performance analysis of proposed three overload control methods is conducted to present the more optimal than methods using in conventional TDX-10 and EWSD by simulation with the assumed model. From simulation result, the two methods except TDX-10L are satisfied with 90% of the designed processor engineered capacity.

아시아 경기대회의 서구화와 그 반성

임영무,안희숙 한국체육사학회 2001 체육사학회지 Vol.7 No.-

We together had a chance to think over the subject of Asian Games. It may looks issuance of regionalism or nationalism against the current on of globalization however, in order to find the ways for the further development of the spirit of Asian Games, it is believed that it's time to open the discussion on it. We also did put efforts to search the next deploying goals of the Asian Games, while reviewing both positive and negative aspects of the Games through the chronological investigation of Asian Games history, and researching the situational aspects of pre-modern and modern Asian sports. Thinking over the two aspects, positive and negative viewpoints, of the general effects of the Asian Games to Asian sports, the 4 positive effects of Asian Games may be pointed out ; ①that Asian Games affected to solidify the generalization of the culture of sports attributed to bringing the perception change about sports in Asian people, ② that it also contributed to spreading the Asia-origin sports to the world ③ that it established the infrastructure of sports in Asia through changing the game holding place among Asian countries, and ④ that it provided the good chances to exchange the national cultures among Asian countries. On the other hand the negative aspects may be mentioned ; ①that the loss of Asian traditional sports culture could be ascribed to the fact that the western sports has been the mainstream in Asian Games ② that the magnitude expansion strategy of the Games limited the number of Game hosting cities, so that only a few cities could hold the Game thus far, ③ that the original spirit of Asian Games has been impaired by making political use of Asian Games like the case of Olympic Games, and ④ that the deployment of diversity of world sports cultures into Asia was not enough Directions that Asian Games in 21st century is moving forward can be ; ① to study the Games operation centered on Asian traditional sports, ② to put efforts on magnitude optimization of the Game in size ③ seek the ways exclude the various non-sports ideologies in order for Asian Games to be the untained place of Asian harmony and advancement. To act Asian Games as a role to promote the Asian peace and goodwill among the Asian countries, the hosting country of the Games needs to establish the (hosting) policies and procedures toward of reconciling the different opinions among the member countries and enhancing the friendships, and to implement it. All participants to the international Games are requested to contribute to both the goodwill of Asian countries and world peace by the sportsmanship, the reciprocal cooperative competition.

Random Amplification of Polymorphic DNA(RAPD)를 이용한 Yersinia enterocolitica의 PCR Fingerprinting비교

임순영,윤석권 동덕여자대학교 생활과학연구소 2006 생활과학연구 Vol.11 No.-

The lamer single primer was used to generate random amplification of polymorphic DNA(RAPD) profiles by polymerase chain reaction(PCR) for 100 strains of Y. enterocolitica from various sources. The RAPD pattern within same serotype was devided into different subtypes and also RAPD pattern of different serotypes showed same RAPD type. Regardless of serotype for Y. enterocolitica, DNA fingerprinting bands of non-pathogenic strains were a few in number and small in size but those of pathogenic were reversed. Every serotype showed unique RAPD pattern. therefore it is possible to discriminate within Y. enterocolitica strains. Showing some strains no band or a few, RAPD is effective method to subtype the strains. If RAPD was utilized with serotyping and biotyping, it should be powerful tool to devide Y. enterocolitica strains for epidem iological purpose.

증후성 Rathke열 낭종 : Transseptal transsphenoidal approach via columella flap

임동명,전세영,장석정 조선대학교 부설 의학연구소 1999 The Medical Journal of Chosun University Vol.24 No.1

Rathke's cysts are sellar and suprasellar lesions that are found incidentally in about 13-22% of autopsy cases. Clinical symptoms of Rathke's cyst are usually the result of local mass effect. The most common symptom is headache, and other symptoms which arise are pituitary dysfunction, compression of the visual apparatus and the pituitary stalk. It is very important to distinguish Rathke's cyst from craniopharyngiomas(more common cystic tumor) because of the operative management. We reported a rare case of symptomatic Rathke's cleft cyst. This cyst was removed by transseptal transsphenoidal approach via columella flap. Postop result was satisfactory without serious complications.