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( Yihui Cheng ) 한국체육학회 2015 국제스포츠과학 학술대회 Vol.2015 No.1
Purpose: the effect of university sport has always been ignored by people, while in fact it really has a deep and wide effect to the area around the university. There are several famous universities in Jimei district, Xiamen, China, dragon boat racing has already become an important part of university sport in these universities, people not only students but also local people, tourists all attracted by the exciting chinese traditional sports game. This study has the objective to explore the effects that the university sport----university dragon boat racing provides to build the eco-city, analyze its social, economical, educational and cultural functions and find a good way for its own development in the process of building the eco-city. Method: The methods used in the study are field research, literature review and expert interview. The methods used here is to review the former research for finding the experience and to find the real function of university dragon boat racing for building the eco-city. Result: university dragon boat racing is not only a school game affecting the schools where it played, which is also a game affecting the area around the university. The effect includes social area, cultural environment, education and economical development. All these parts are the element of eco-environment, so the racing has great effect to eco-environment. Just because of these effects, the society made a good environment for the development of university dragon boat racing. For developing university dragon boat racing well, it should find a suitable way to match the city``s image and explore the culture value. university dragon boat racing is also a way for education, teaching the tradional culture. Conclusion: Firstly, the university dragon boat racing has great effect for building the eco-city, which has social function, educational function, cultural function and economical function. Secondly, to fulfill these function, university dragon boat racing should find its own way both for its self-development and affecting the environment.
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The cytoplasmic loops of AgrC contribute to the quorum-sensing activity of Staphylococcus aureus
Huang Qian,Xie Yihui,Yang Ziyu,Cheng Danhong,He Lei,Wang Hua,Liu Qian,Li Min 한국미생물학회 2021 The journal of microbiology Vol.59 No.1
In Staphylococcus aureus, the accessory gene regulator (agr) quorum-sensing system is thought to play an important role in biofilm formation. The histidine kinase AgrC is one of the agr system components and activated by the self-generated auto-inducing peptide (AIP), which is released continuously into the extracellular environment during bacterial growth. The extracellular loops (Extra-loops) of AgrC are crucial for AIP binding. Here, we reported that the cytoplasmic loops (Cyto-loops) of AgrC are also involved in Agr activity. We identified S. aureus ST398 clinical isolates containing a naturally occurring single amino acid substitution (lysine to isoleucine) at position 73 of an AgrC Cyto-loop that exhibited significantly stronger biofilm formation and decreased Agr activity compared to the wild-type strain. A constructed strain containing the K73I point mutation in AgrC Cyto-loop continued to show a growth dependent induction of the agr system, although the growth dependent induction was delayed by about 6 h compared to the wild-type. In addition, a series of strains containing deletion mutants of the AgrC Cyto- and Extra-loops were constructed and revealed that the removal of the two Cyto-loops and Extra-loops 2 and 3 totally abolished the Agr activity and the growth-dependence on the agr system induction. Remarkably, the Extra-loop 1 deletion did not affect the Agr activity. In conclusion, the AgrC Cyto-loops play a crucial role in the S. aureus quorum-sensing activity.
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