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- 저자 : ( Xinli Hu ) (검색결과 247 건)
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( Xinli Hu ) 대한지질공학회 2019 대한지질공학회 학술발표회논문집 Vol.2019 No.2
Piles have been widely used to stabilize landslides in reservoir area. The interaction between stabilizing piles and landslide body is complicated and is vital for evaluating the long-term safety of landslides and reservoirs. Taking the Majiagou landslide in Hubei Province, China, as a prototype, two physical models with and without piles were constructed with a geometrical similarity ratio of 1:40. The water level in the models was raised and maintained to an elevation of 0.89 m. The deformation, earth pressure, and pore-water pressure of the landslide and the strain of one representative pile were recorded during the tests. The comparison between the model with piles and that without piles shows that: (1) Piles significantly improved the deformation resistance of landslides. Landslides with piles can tolerate a larger deformation before failure and the displacement rate of landslides after failure was reduced; (2) The implantation of piles changed the soil pressure distribution of landslides. The soil pressures at the upslope and around the piles increased while those at the downslope decreased. The distribution of soil pressures along the depth at the uphill and downhill side of the piles changed from triangular to invert triangular and parabolic, respectively; (3) Piles arrested the anticipant slip surface that occurred in an unreinforced landslide, and at least two sliding bands traversed the landslide. (4) Comparison of the pile-reinforced landslide model with those in literature with piles with a much higher stiffness show that the stiffness of piles significantly affects the mechanical interaction between piles and landslides.
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Research on the Variable Rate Spraying System Based on Canopy Volume Measurement
Hu, Kaiqun,Feng, Xin Korea Information Processing Society 2019 Journal of information processing systems Vol.15 No.5
Characteristics of fruit tree canopies are important target information for adjusting the pesticide application rate in variable rate spraying in orchards. Therefore, the target detection of the canopy characteristics is very important. In this study, a canopy volume measurement method for peach trees was presented and a variable rate spraying system based on canopy volume measurement was developed using the ultrasonic sensing, one of the most effective target detection method. Ten ultrasonic sensors and two flow control units were mounted on the orchard air-assisted sprayer. The ultrasonic sensors were used to detect the canopy diameters and the flow controls were used to modify the flow rate of the nozzles in real time. Two treatments were established: a constant application rate of $300Lha^{-1}$ was set as the control treatment for the comparison with the variable rate application at a $0.095Lm^{-3}$ canopy. The tracer deposition at different parts of peach trees and the tracer losses to the ground (between rows and within rows) were analyzed in detail under constant rate and variable rate application. The results showed that there were no significant differences between two treatments in the liquid distribution and the capability to reach the inner parts of the crop canopies.
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Hu, Ke,Xie, Zheng,Wang, Zuo-Cai,Ren, Wei-Xin,Chen, Lei-Ke Techno-Press 2018 Structural monitoring and maintenance Vol.5 No.1
In order to provide a novel strategy for long-span bridge health monitoring system design, this paper proposes a novel ultimate bearing capacity ratios based bridge internal force monitoring design method. The bridge ultimate bearing capacity analysis theories are briefly described. Then, based on the ultimate bearing capacity of the structural component, the component ultimate bearing capacity ratio, the uniformity of ultimate bearing capacity ratio, and the reference of component ultimate bearing capacity ratio are defined. Based on the defined indices, the high bearing components can then be found, and the internal force monitoring system can be designed. Finally, the proposed method is applied to the bridge health monitoring system design of the second highway bridge of Wuhu Yangtze river. Through the ultimate bearing capacity analysis of the bridge in eight load conditions, the high bearing components are found based on the proposed method. The bridge internal force monitoring system is then preliminary designed. The results show that the proposed method can provide quantitative criteria for sensors layout. The monitoring components based on the proposed method are consistent with the actual failure process of the bridge, and can reduce the monitoring of low bearing components. For the second highway bridge of Wuhu Yangtze river, only 59 components are designed to be monitored their internal forces. Therefore, the bridge internal force monitoring system based on the ultimate bearing capacity ratio can decrease the number of monitored components and the cost of the whole monitoring system.
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Hu, Nan,Wang, Zhaoming,Song, Xin,Wei, Lixuan,Kim, Byung Sik,Freedman, Neal D,Baek, Jiwon,Burdette, Laurie,Chang, Jiang,Chung, Charles,Dawsey, Sanford M,Ding, Ti,Gao, Yu-Tang,Giffen, Carol,Han, Yaling British Medical Association 2016 Gut Vol.65 No.10
<P>Objective Genome-wide association studies (GWAS) of gastric cancer have reported differences in single-nucleotide polymorphism (SNP) associations for tumour subtypes, particularly when divided by location into the gastric cardia versus the non-cardia. Design Here we present results for a GWAS using 2350 East Asian gastric cancer cases divided as 1189 gastric cardia and 1027 gastric non-cardia cases and 2708 controls. We also included up to 3042 cardia cases, 4359 non-cardia cases and 7548 controls for replication from two Chinese studies and one Korean study. From the GWAS, we selected 12 top SNPs for each gastric cancer subtype, 4 top SNPs for total gastric cancer and 1 SNP in MUC1 for replication testing. Results We observed genome-wide significant associations for rs10074991 in PRKAA1 at 5p13.1 for cardia (p=7.36x10(-12)) and non-cardia cancers (p=2.42x10(-23)) with per allele OR (95% CI) for the combined endpoint of 0.80 (0.77 to 0.83). At 6p21.1, rs2294693 near UNC5CL was significantly associated with gastric non-cardia cancer risk (p=2.50x10(-8)), with OR (95% CI) of 1.18 (1.12 to 1.26), but there was only a nominal association for cardia cancer (p=1.47x10(-2)). We also confirmed a previously reported association for rs4072037 in MUC1 with p=6.59x10(-8) for total gastric cancer and similar estimates for cardia and non-cardia cancers. Three SNPs in PSCA previously reported to be associated with gastric non-cardia cancer showed no apparent association for cardia cancer. Conclusions Our results suggest that associations for SNPs with gastric cancer show some different results by tumour location in the stomach.</P>
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Precirrhotic Primary Biliary Cholangitis with Portal Hypertension: Bile Duct Injury Correlate
Hu Yi-Fan,Li Shun-Xin,Liu Hong-Li,Du Zhi-Xiang,Wang Shuang-Shuang,Chen Miao-Yang,Wang Li,Xiong Qing-Fang,Zhong Yan-Dan,Liu Du-Xian,Yang Yong-Feng 거트앤리버 소화기연관학회협의회 2024 Gut and Liver Vol.18 No.5
Background/Aims: The histological characteristics and natural history of precirrhotic primary biliary cholangitis (PBC) with portal hypertension (PH) are unclear. Our aim was to clarify the prevalence, risk factors, and histological characteristics of precirrhotic PBC patients with PH. Methods: This retrospective study compared the clinical features, histological characteristics, and response to ursodeoxycholic acid (UDCA) between the PH and non-PH groups of precirrhotic PBC patients. Results: Out of 165 precirrhotic PBC patients, 40 (24.2%) also had PH. According to histological stage 1, 2 and 3 disease, 5.3% (1/19), 17.3% (17/98), and 45.8% (22/48) of patients also had PH, respectively. Precirrhotic PBC with PH was significantly positively correlated with bile duct loss, degree of cytokeratin 7 positivity, and degree of fibrosis in the portal area, but significantly negatively correlated with lymphoid follicular aggregation. Compared to the non-PH group, patients in the PH group showed a higher prevalence of obliterative portal venopathy, incomplete septal fibrosis, portal tract abnormalities and non-zonal sinusoidal dilatation (p<0.05). In addition, patients with PH were more likely to present with symptoms of jaundice, ascites, epigastric discomfort, a poorer response to UDCA, and more decompensation events (p<0.05). High alkaline phosphatase levels, low white blood cell counts, high Mayo scores, and high FIB-4 index values were risk factors for precirrhotic PBC with PH. Conclusions: Approximately 24.2% of precirrhotic PBC patients have PH, which is histologically related to the injury of bile ducts. High alkaline phosphatase levels, low white blood cell counts, high Mayo scores, and high FIB-4 index values are associated with increased risk of precirrhotic PBC with PH.
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Xin-Yue Liu,Qing-Fang Yue,Lei Chen,Xiao-Mei She,Bin Hu,Yu Hu,Ping Zou 연세대학교의과대학 2016 Yonsei medical journal Vol.57 No.2
Purpose: The objective was to determine the characteristics and prognostic factors of 86 Chinese patients with trisomy 8 aberrationsand compare the prognostic value of International Prognostic System (IPSS) and Revised IPSS (IPSS-R) in this cohort. Materials and Methods: A total of 86 cases diagnosed with primary myelodysplastic syndromes (MDS) with isolated tr8 or with tr8 and other additional cytogenetic aberrations diagnosed and treated at the Union Hospital, Tongji Medical College of Huazhong University of Science and Technology between July 2002 and March 2013 were reviewed. Results: The median survival of the entire group was 23.0 months, and acute myeloid leukemia (AML) developed in 43% (37/86) patients within the follow up time. The univariate analysis revealed that overall survival (OS) was correlated with age, thrombocytopenia,absolute neutrophil count, marrow blasts, cytogenetic status and red blood cell transfusion at diagnosis, and the multivariateanalysis revealed that age, marrow blasts, cytogenetic status and transfusion dependence were independent parameters for the OS. The cytogenetic complexity and marrow blasts had the strongest impact on the AML transformation by multivariate analysis. Comparing the two prognostic systems, both two systems could successfully discriminate risk groups for survival. IPSS-R was more refined than IPSS for predicting OS, but had no advantage in predicting the risk of AML development. Conclusion: This study confirmed the influence of clinical factors on the prognosis of 86 Chinese MDS patients with trisomy 8. In addition, IPSS-R can further refine prognostic discrimination in the IPSS risk categories.
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Xin Li,Yancheng Li,Yuanhao Liang,Ruixue Hu,Wenli Xu,Yufeng Liu 대한당뇨병학회 2021 Diabetes and Metabolism Journal Vol.45 No.2
Background: We hypothesized that specific amino acids or acylcarnitines would have benefits for the differential diagnosis of diabetes. Thus, a targeted metabolomics for amino acids and acylcarnitines in patients with diabetes and its complications was carried out. Methods: A cohort of 54 normal individuals and 156 patients with type 2 diabetes mellitus and/or diabetic complications enrolled from the First Affiliated Hospital of Jinzhou Medical University was studied. The subjects were divided into five main groups: normal individuals, impaired fasting glucose, overt diabetes, diabetic microvascular complications, and diabetic peripheral vascular disease. The technique of tandem mass spectrometry was applied to obtain the plasma metabolite profiles. Metabolomics multivariate statistics were applied for the metabolic data analysis and the differential metabolites determination. Results: A total of 10 cross-comparisons within diabetes and its complications were designed to explore the differential metabolites. The results demonstrated that eight comparisons existed and yielded significant metabolic differences. A total number of 24 differential metabolites were determined from six selected comparisons, including up-regulated amino acids, down-regulated medium-chain and long-chain acylcarnitines. Altered differential metabolites provided six panels of biomarkers, which were helpful in distinguishing diabetic patients. Conclusion: Our results demonstrated that the biomarker panels consisted of specific amino acids and acylcarnitines which could reflect the metabolic variations among the different stages of diabetes and might be useful for the differential diagnosis of prediabetes, overt diabetes and diabetic complications.
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Research on the Multi-Focus Image Fusion Method Based on the Lifting Stationary Wavelet Transform
Hu, Kaiqun,Feng, Xin Korea Information Processing Society 2018 Journal of information processing systems Vol.14 No.5
For the disadvantages of multi-scale geometric analysis methods such as loss of definition and complex selection of rules in image fusion, an improved multi-focus image fusion method is proposed. First, the initial fused image is quickly obtained based on the lifting stationary wavelet transform, and a simple normalized cut is performed on the initial fused image to obtain different segmented regions. Then, the original image is subjected to NSCT transformation and the absolute value of the high frequency component coefficient in each segmented region is calculated. At last, the region with the largest absolute value is selected as the postfusion region, and the fused multi-focus image is obtained by traversing each segment region. Numerical experiments show that the proposed algorithm can not only simplify the selection of fusion rules, but also overcome loss of definition and has validity.
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