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- 저자 : ( T. M. Meaz ) (검색결과 3 건)
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Promising Fe3O4/CdSe Nanocomposites for Rug Delivery in Liver Cancer Treatment
( Shaimaa A. Habib ),( M. B. Mohamed ),( S. A. Saafan ),( T. M. Meaz ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1
Aims: Nowadays, magnetic semiconductors nanocomposites have become a new class of materials of great importance promising with new properties and exploiting unique incorporation between materials. For example, one can make use of a variety of spin-related phenomena, not readily available in other materials. this work concentrates on synthesis of magnetic iron oxide nanoparticles (MNs) and Cadmium Selenide (CdSe) quantum dots (QDs). CdSe QDs have attractive optical properties such as bright fluorescence emission and wide absorption band in the visible region and they possess the ability to act as energy donors through Förster resonance energy transfer (FRET). MNs also are known to have interesting applications in biomedical field and drug delievery system. Methods: In the present work, bi-functional magnetic-luminescent nanocomposites with Fe<sub>3</sub>O<sub>4</sub> nanoparticles as the cores and CdSe as the shells have been synthesized by a facile direct precipitation method. Transmission electron microscopy (TEM) images revealed that the obtained bi-functional nanocomposites had a core-shell structure. The flower shape has been ascribed to the inhomogeneous growth of CdSe due to the presence of many active sites which turn to be nucleation centers for the CdSe on the surface of the nano-magnetite. The X-ray diffraction (XRD) patterns ensured the cubic spinel structure of the Fe<sub>3</sub>O<sub>4</sub> core. Results: Magnetic measurements indicated that the presence of CdSe in the composite has reduced its magnetic properties. Optical measurements of the Fe<sub>3</sub>O<sub>4</sub>/CdSe nanocomposites showed that the prepared samples have dual functions, optical tunable band gap similar to the semiconductor quantum dots and magnetic properties due to Fe<sub>3</sub>O<sub>4</sub> nanoparticles. According to the values of Stokes shift of the new hybrid composites, one can suggest that they may be promising in drug delivery (liver cancer treatment). All of the first line of result idicate that all of fabricated samples are so promising in drug delivery system. Conclusions: Fe<sub>3</sub>O<sub>4</sub> nanoparticles has been successfully prepared by the co-precipetation method. The have been investigated via XRD, TEM and VSM. The XRD confirms the formation of the required cubic ferrite without other unwanted phases. The Fe<sub>3</sub>O<sub>4</sub>has been used as a seed or as a core to grow CdSe nanoshell around. The obtained hybrid Fe<sub>3</sub>O<sub>4</sub> nanostructure has flower shape particles. The Fe<sub>3</sub>O<sub>4</sub>/CdSe nanocomposites has larger quantum yield values thanthose of pure CdSe QDs may be due to the fact that magnetic nanoparticles facilitate the electron holerecombination and enhance the emission from the quantum dots. In other words, the presence of Fe<sub>3</sub>O<sub>4</sub> enhances the optical properties of CdSe quantum dots. The prepared nanocomposites have dual functions, optical tunable band gap similar to the semiconductor quantum dots and magnetic properties due to Fe<sub>3</sub>O<sub>4</sub>nanoparticles. This composite would be considered as dilute magnetic-semiconductor and could be used in spintronics, biosensors, solarcells and biomedical lables which could confirm that these nanoparticles could be a suitable drug delievery tool for many anticancer agent in the future.
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Study of Photon Strength Function of Actinides: the Case of ^(235)U, ^(238)Np and ^(241)Pu
C. Guerrero,F. Alvarez-Velarde,D. Cano-Ott,T. Martinez,E. Mendoza,D. Villamarin,N. Colonna,M. H. Meaze,S. Marrone,G. Tagliente,R. Terlizzi,F. Belloni,U. Abbondanno,K. Fujii,P. M. Milazzo,C. Moreau,G. 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23
The decay from excited levels in medium and heavy nuclei can be described in a statisticalapproach by means of Photon Strength Functions and Level Density distributions. The study of electromagnetic cascades following neutron capture based on the use of high eciency detectors has been shown to be well suited for probing the properties of the Photon Strength Function of heavy (high level density) and/or radioactive (high background) nuclei. In this work we have investigated for the first time the validity of the recommended PSF of actinides, in particular ^(235)U, ^(238)Np and ^(241)Pu. Our study includes the search for resonance structures in the PSF below S_n and draws conclusions regarding their existence and their characteristics in terms of energy, width and electromagnetic nature.
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D. Cano-Ott,F. Alvarez-Velarde,E. Gonzalez-Romero,C. Guerrero,T. Martinez,E. Mendoza,D. Villamarin,M. C. Vicente,U. Abbondanno,N. Colonna,M. H. Meaze,S. Marrone,G. Tagliente,R. Terlizzi,F. Belloni,K. 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23
The successful development of advanced nuclear systems for sustainable energy production and nuclear waste management depends on high quality nuclear data libraries. Recent sensitivity studies and reports [1][2][3] have identified the need for substantially improving the accuracy of neutron cross-section data for minor actinides. The n_TOF collaboration has initiated an ambitious experimental program for the measurement of neutron capture cross sections of minor actinides. Two experimental setups have been constructed for this purpose: a Total Absorption Calorimeter (TAC) [4] for measuring neutron capture cross-sections of low-mass and/or radioactive samples and a set of two low neutron sensitivity C_6D_6 detectors for the less radioactive materials.
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