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        주민참여예산제도 활성화 방안

        유홍성(Yoo, Hong-Sung),남승균(Nam, Seung-Kyun),신진영(Shin, Chin-Young),임영숙(Lim, Young-Sook) 인천대학교 인천학연구원 2014 인천학연구 Vol.21 No.-

        본 연구는 주민참여예산제도 활성화 방안에 대한 요인을 도출하고 도출된 요인을 관련 공무원과 주민참여예산 위 원들의 설문조사를 통해 실증분석 하고, 또한 인천 남구 주민참여예산제도 운영에 대한 분석을 하였다. 연구결과 주민참여예산에 관한 요인은 ‘주민참여예산제도 기반형성’, ‘주민참여예산제도 성공요인’으로 구분됨을??확인하였고 이들 차원과 주민참여예산제도 시행효과의 인과관계와 각 요인에 대해 관련 공무원과 주민참여예산??위원들 두 집단이 차이가 있는지를 살펴본 결과 주민참여예산제도 기반형성과 주민참여예산제도 성공요인이 주민 참여예산제도 시행효과에 통계적으로 유의하게 나타났다. 또한 각 요인에 대한 관련 공무원과 주민참여예산 위원 들 두 집단에 대한 차이분석 결과 통계적으로 유의하게 차이가 있음을 확인하였다. 추가적으로 공무원과 주민참여 예산 위원들 각각 회귀분석 비교분석 결과 공무원은 주민참여예산제도 성공요인을 중요하게 생각하고 있으며, 위 원들은 기반형성 구축이 주민참여예산제도 시행효과에 더 중요하게 영향을 미치는 것으로 인식하고 있다, 주민참 여예산제도의 활성화를 위해서는 참여가치에 대한 공감대, 지역사회나 관련조직의 의견수렴, 교류를 위한 네트워 크 구축 등의 기반형성과 주민참여예산제도의 범위를 예산편성에서 예산 전반의 참여권한 확대가 필요하고, 공무 원의 적극적인 지원 활동 등 주민참여예산제도 성공요인 관리가 필요하다. This study derived factors related to the activation of citizen participatory budgeting, analyzed the factors??positively through a questionnaire survey of involved civil servants and participatory budgeting committee??members, and made analysis of participatory budgeting system for operation in the Incheon Nam-Gu area. According to the results of this study, factors related to participating budgeting were largely divided into??‘footing of citizen participatory budgeting’ and ‘success factors of citizen participatory budgeting.’ In the??results of examining the causal relationship between these dimensions and the effect of citizen participatory??budgeting system and seeing if there was any difference in each factor between involved civil servants and??participatory budgeting committee members, footing of citizen participatory budgeting and the success factors??of citizen participatory budgeting were statistically significantly correlated with the effect of citizen participatory??budgeting sysytem. In addition, a statistically significant difference was observed in each factor between??involved civil servants and participatory budgeting committee members. In additional comparative regression??analysis between civil servants and participatory budgeting committee members, civil servants attached more??importance to the success factors of citizen participatory budgeting, but committee members considered the??footing of the system more important for the effect of citizen participatory budgeting. What are required for the??activation of citizen participatory budgeting system are consensus on the value of participation, opinion??collection from communities and related organizations, construction of networks for exchange, and the??extension of the scope of participatory budgeting from budgeting to the whole range of budget?related areas.??What is more, the success factors of participatory budgeting including civil servants’ active support need to be??managed properly.

      • Prediction of distant metastasis and survival in adenoid cystic carcinoma using quantitative <sup>18</sup>F-FDG PET/CT measurements

        Lim, Won Sub,Oh, Jungsu S.,Roh, Jong-Lyel,Kim, Jae Seung,Kim, Soo-Jong,Choi, Seung-Ho,Nam, Soon Yuhl,Kim, Sang Yoon Elsevier 2018 Oral oncology Vol.77 No.-

        <P><B>Abstract</B></P> <P><B>Objectives</B></P> <P>Adenoid cystic carcinoma (AdCC) in the salivary gland shows a high rate of distant metastasis, which is related to the resulting poor prognosis. We therefore examined the role of pretreatment <SUP>18</SUP>F-FDG PET/CT for prediction of distant metastasis, recurrence/progression, and survival in AdCC.</P> <P><B>Methods</B></P> <P>This study included 52 patients who underwent pretreatment <SUP>18</SUP>F-FDG PET/CT scanning and subsequent treatments for AdCC. Maximum, mean, and peak standardized uptake value (SUV<SUB>max</SUB>, SUV<SUB>mean</SUB>, and SUV<SUB>peak</SUB>), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) were measured on <SUP>18</SUP>F-FDG PET/CT. Univariate and multivariate Cox proportional hazards regression analyses were used to identify associations between the quantitative measurements of <SUP>18</SUP>F-FDG PET, and progression-free survival (PFS), distant metastasis-free survival (DMFS), and disease-specific survival (DSS).</P> <P><B>Results</B></P> <P>Distant metastases were found in 20 (39%) patients: 6 (12%) at initial diagnosis and 14 (27%) during the median follow-up of 72 months after treatment. Univariate analyses showed that all the <SUP>18</SUP>F-FDG PET parameters of SUV<SUB>max</SUB>, SUV<SUB>mean</SUB>, SUV<SUB>peak</SUB>, MTV, and TLG were significantly associated with overall PFS, DMFS, and OS (all <I>P</I> < .05). After controlling for clinicopathological variables, SUV<SUB>max</SUB> remained an independent factor predictive of PFS (<I>P</I> = .001), while MTV and TLG were independent predictors of DMFS (<I>P</I> = .009) and DSS (<I>P</I> = .017). Patients with MTV > 14.8 mL showed a 5.9-fold higher risk of distant metastasis and a 4.2-fold higher risk of disease-specific death than those with a lower MTV.</P> <P><B>Conclusions</B></P> <P>Quantitative measurements using <SUP>18</SUP>F-FDG PET/CT are useful for predicting tumor progression, distant metastasis, and survival in patients with AdCC.</P> <P><B>Highlights</B></P> <P> <UL> <LI> SUV<SUB>max</SUB>, SUV<SUB>mean</SUB>, SUV<SUB>peak</SUB>, MTV, and TLG were measured on pretreatment <SUP>18</SUP>F-FDG PET/CT of 52 adenoid cystic carcinoma patients. </LI> <LI> SUV<SUB>max</SUB> (>3.2) was an independent factor predictive of progression-free survival (<I>P</I> = .001). </LI> <LI> MTV and TLG were independent predictors of distant metastasis-free and disease-specific survival (<I>P</I> < .05) </LI> <LI> MTV > 14.8 mL or TLG > 45.5 g was associated with a >4-fold increased risk of distant metastasis and mortality. </LI> </UL> </P>

      • Auxin response factor 2 (ARF2) plays a major role in regulating auxin-mediated leaf longevity

        Lim, Pyung Ok,Lee, In Chul,Kim, Junyoung,Kim, Hyo Jung,Ryu, Jong Sang,Woo, Hye Ryun,Nam, Hong Gil Oxford University Press 2010 Journal of experimental botany Vol.61 No.5

        <P>Auxin regulates a variety of physiological and developmental processes in plants. Although auxin acts as a suppressor of leaf senescence, its exact role in this respect has not been clearly defined, aside from circumstantial evidence. It was found here that <I>ARF2</I> functions in the auxin-mediated control of <I>Arabidopsis</I> leaf longevity, as discovered by screening EMS mutant pools for a delayed leaf senescence phenotype. Two allelic mutations, <I>ore14-1</I> and <I>14-2</I>, caused a highly significant delay in all senescence parameters examined, including chlorophyll content, the photochemical efficiency of photosystem II, membrane ion leakage, and the expression of senescence-associated genes. A delay of senescence symptoms was also observed under various senescence-accelerating conditions, where detached leaves were treated with darkness, phytohormones, or oxidative stress. These results indicate that the gene defined by these mutations might be a key regulatory genetic component controlling functional leaf senescence. Map-based cloning of <I>ORE14</I> revealed that it encodes ARF2, a member of the auxin response factor (ARF) protein family, which modulates early auxin-induced gene expression in plants. The <I>ore14/arf2</I> mutation also conferred an increased sensitivity to exogenous auxin in hypocotyl growth inhibition, thereby demonstrating that ARF2 is a repressor of auxin signalling. Therefore, the <I>ore14/arf2</I> lesion appears to cause reduced repression of auxin signalling with increased auxin sensitivity, leading to delayed senescence. Altogether, our data suggest that ARF2 positively regulates leaf senescence in <I>Arabidopsis</I>.</P>

      • SCISCIESCOPUS

        Pyridine-functionalized graphene/polyimide nanocomposites; mechanical, gas barrier, and catalytic effects

        Lim, Jun,Yeo, Hyeonuk,Kim, Seo Gyun,Park, Ok-Kyung,Yu, Jaesang,Hwang, Jun Yeon,Goh, Munju,Ku, Bon-Cheol,Lee, Heon Sang,You, Nam-Ho Elsevier 2017 Composites Part B, Engineering Vol.114 No.-

        <P><B>Abstract</B></P> <P>In this paper, we describe a functionalization route for synthesizing pyridine-functionalized reduced graphene oxide (Py-rGO) and the effect in the polymer matrix. In addition, polyimide (PI) nanocomposites with different loadings of Py-rGO are fabricated by in-situ polymerization. Py-rGO can perform as a filler component, which enhances the mechanical properties of the composites as well as promote polycondensation as a catalyst. As a result, the PIs containing Py-rGO are obtained with a high degree of imidization and the nanocomposite films show improved mechanical properties and oxygen barrier properties compared to pure PI. To be specific, the tensile strength and tensile modules of the nanocomposite with 0.5 wt% loading of Py-rGO are enhanced by about 406% (527 MPa) and 928% (59 GPa) in comparison to those of pure PI, respectively. Furthermore, the oxygen barrier properties of the composites are extremely improved.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • KCI등재

        A cluster of tertiary transmissions of 2019 novel coronavirus (SARS-CoV-2) in the community from infectors with common cold symptoms

        Nam Joong Kim,Pyoeng Gyun Choe,Sang-Joon Park,Jaegyun Lim,이왕준,Chang Kyung Kang,Wan Beom Park,Moon-Woo Seong,Myoung-don Oh 대한내과학회 2020 The Korean Journal of Internal Medicine Vol.35 No.4

        Background/Aims: As the global impact of the novel coronavirus disease 2019 (COVID-19) has been severe, many countries have intensified containment activities to eliminate virus transmission, through early detection and isolation strategies. To establish a proper quarantine strategy, it is essential to understand how easily the virus can spread in the communities. Methods: In this study, we collected detailed information on the circumstances in which human-to-human transmission occurred in the tertiary transmission cases of COVID-19 in the community. Results: On January 26, 2020, an imported case of COVID-19 was confirmed, and by February 10, 2020, one secondary transmission and three tertiary transmissions were identified. Secondary transmission occurred on the first day of illness of the infector, and his symptoms were suggestive of a common cold. The transmission occurred during a 90-minute long meal together in a restaurant. The people were sitting within one meter of each other, and had no direct contact. The tertiary transmission also occurred on the first-day illness of the other infector, and his only symptom was slight chills. The transmission occurred at a church during 2-hour-long worship, and two rows separated them. Conclusions: Our f indings suggest that mildly symptomatic patients with COVID-19 could transmit the virus from the first day of illness through daily activities in the community. Early detection and isolation of patients with COVID-19 may be challenging.

      • Prognostic implications of tumor-infiltrating macrophages, M2 macrophages, regulatory T-cells, and indoleamine 2,3-dioxygenase-positive cells in primary diffuse large B-cell lymphoma of the central nervous system

        Nam, Soo Jeong,Kim, Sehui,Kwon, Dohee,Kim, Hannah,Kim, Soyeon,Lee, Eunyoung,Kim, Tae Min,Heo, Dae Seog,Park, Sung Hye,Lim, Megan S.,Kim, Chul Woo,Jeon, Yoon Kyung TaylorFrancis 2018 Oncoimmunology Vol.7 No.7

        <P><B>ABSTRACT</B></P><P>Primary diffuse large B-cell lymphoma of the central nervous system (CNS-DLBCL) is an aggressive disease with a poor prognosis. The status of the tumor immune microenvironment in CNS-DLBCL remains unclear. We investigated the prognostic implications of tumor-associated macrophages (TAMs), regulatory T-cells (Tregs), and indoleamine 2,3-dioxygenase (IDO)<SUP>+</SUP> cells in primary CNS-DLBCL (n = 114) by immunohistochemical analysis. The numbers of tumor-infiltrating immune cells, including CD68<SUP>+</SUP> TAMs, CD163<SUP>+</SUP> or CD204<SUP>+</SUP> M2 macrophages, FOXP3<SUP>+</SUP> Tregs, and IDO<SUP>+</SUP> cells were all significantly lower in CNS-DLBCL versus systemic DLBCL (n = 165; all P < 0.001), but with little difference in the ratio of CD163<SUP>+</SUP>/CD68<SUP>+</SUP> or CD204<SUP>+</SUP>/CD68<SUP>+</SUP> cells. An increase in CD68<SUP>+</SUP> cell numbers was significantly associated with prolonged progression-free survival (PFS) and overall survival in patients with CNS-DLBCL (P = 0.004 and 0.021, respectively). In contrast, an increase in CD204<SUP>+</SUP> cell numbers or a higher ratio of CD204<SUP>+</SUP>/CD68<SUP>+</SUP> cells was related to a shorter PFS (P = 0.020 and 0.063, respectively). An increase in IDO<SUP>+</SUP> cell numbers was associated with a significantly longer PFS (P = 0.019). In combination, the status of low IDO<SUP>+</SUP> cell numbers combined with low CD68<SUP>+</SUP> cell numbers, high CD204<SUP>+</SUP> cell numbers, or a high CD204<SUP>+</SUP>/CD68<SUP>+</SUP> cell ratio all predicted poor PFS in multivariate analyses. This study showed that an increase in CD204<SUP>+</SUP> cell numbers, suggestive of M2 macrophages, was associated with poor clinical outcome in CNS-DLBCL, whereas increased CD68<SUP>+</SUP> or IDO<SUP>+</SUP> cell numbers were related to a favorable prognosis. The analysis of tumor-infiltrating immune cells could help in predicting the prognosis of CNS-DLBCL patients and determining therapeutic strategies targeting tumor microenvironment.</P>

      • SCOPUSKCI등재

        Free Flap Reconstruction of Head and Neck Defects after Oncologic Ablation: One Surgeon's Outcomes in 42 Cases

        Lim, Yun Sub,Kim, Jun Sik,Kim, Nam Gyun,Lee, Kyung Suk,Choi, Jae Hoon,Park, Sang Woo Korean Society of Plastic and Reconstructive Surge 2014 Archives of Plastic Surgery Vol.41 No.2

        Background Free flap surgery for head and neck defects has gained popularity as an advanced microvascular surgical technique. The aims of this study are first, to determine whether the known risk factors such as comorbidity, tobacco use, obesity, and radiation increase the complications of a free flap transfer, and second, to identify the incidence of complications in a radial forearm free flap and an anterolateral thigh perforator flap. Methods We reviewed the medical records of patients with head and neck cancer who underwent reconstruction with free flap between May 1994 and May 2012 at our department of plastic and reconstructive surgery. Results The patients included 36 men and 6 women, with a mean age of 59.38 years. The most common primary tumor site was the tongue (38%). The most commonly used free flap was the radial forearm free flap (57%), followed by the anterolateral thigh perforator free flap (22%). There was no occurrence of free flap failure. In this study, risk factors of the patients did not increase the occurrence of complications. In addition, no statistically significant differences in complications were observed between the radial forearm free flap and anterolateral thigh perforator free flap. Conclusions We could conclude that the risk factors of the patient did not increase the complications of a free flap transfer. Therefore, the risk factors of patients are no longer a negative factor for a free flap transfer.

      • SCISCIESCOPUS

        Visceral fatness and insulin sensitivity in women with a previous history of gestational diabetes mellitus.

        Lim, Soo,Choi, Sung Hee,Park, Young Joo,Park, Kyong Soo,Lee, Hong Kyu,Jang, Hak C,Cho, Nam H,Metzger, Boyd E American Diabetes Association 2007 Diabetes care Vol.30 No.2

        <P>OBJECTIVE: The purpose of this study was to investigate the insulin sensitivity and visceral fatness in women with previous gestational diabetes mellitus (GDM), who are prone to develop type 2 diabetes. RESEARCH DESIGN AND METHODS: A 75-g oral glucose tolerance test (OGTT) performed 1 year postpartum identified 21 GAD(-) women with previous GDM and impaired glucose tolerance (GDM-IGT). Sixty age- and BMI-matched women with normal glucose tolerance (GDM-NGT) were selected by 1:3 matching to the GDM-IGT group. Another 18 women with normal glucose metabolism during a previous pregnancy and no family history of diabetes were recruited as the normal control group. Age and BMI matching was performed using a range of +/-1.0 years and +/-1.0 kg/m(2), respectively. Total body fat was measured by tetrapolar bioelectrical impedance, and visceral fat was determined using a single cut of a computed tomography scan. Insulin sensitivity was determined by the minimal model technique using the frequently sampled intravenous glucose tolerance test. RESULTS: One year postpartum, visceral fat was greater in the GDM-IGT group than in the age- and BMI-matched GDM-NGT or normal control groups. The insulin sensitivity index was lower in the GDM-IGT group than in the GDM-NGT or normal control groups. beta-Cell function, as measured by the acute insulin response to glucose, was also lower in GDM-IGT. CONCLUSIONS: High body fat content, especially visceral fat content, and a low insulin response to glucose seem to contribute simultaneously to the development of impaired glucose metabolism in Korean women with previous GDM.</P>

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