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      • SCOPUSKCI등재
      • KCI등재후보

        반코마이신 내성 장내구균 분리 환자에서 황색포도알균의 내성

        김동욱,신선혜,김혜진,류선,이선희,장철훈,김영대,곽임수 대한감염학회 2004 감염과 화학요법 Vol.36 No.1

        목적 : Vancomycin-resistant enterococci (VRE)로부터 S. aureus로의 vacomycin 내성 유전자의 전파는 오래전부터 예견되어져 왔으며 큰 걱정거리로 남아있다. 최근에 vanA 유전자를 가지고 있는 vancomycin-resistant S. aureus 2주가 미국에서 분리되었다. 이 연구의 목적은 VRE를 보균하고 있는 환자들에서 S. aureus 보균양상과 항균제 내성을 알아보는데 그 목적이 있다. 재료 및 방법 : 2001년 1월부터 2001년 12월까지 부산대학교병원에 입원하였던 환자들 중 임상검체에서 VRE가 분리된 환자 7명과 2001년 9월부터 12월까지 외과 중 환자실에 입원하였던 환자들 중 VRE 감시배양을 시행하였던 20명의 환자들을 대상으로 하였다. 환자들은 전비공, 액와부, 회음부, 직장에서 매주 면봉으로 검체를 채취하였다. 선별배지에서 검체를 배양하여 S. aureus를 분리하였고 원판 확산법을 이용하여 methicillin 감수성을 측정하였다. Broth microdilution 법으로 vancomycin MIC를 측정하였다. 결과 : 총 27명에서 73회의 방문과 292회의 배양이 시행되었으며 총 67주의 S. aureus가 분리되었다. 이중 64주(95.5%)가 methicillin 내성이었다. 전비공 MRSA 보균율은 VRE를 보균하고 있었던 환자는 19명 중 11명(58%)에서, VRE를 보균하지 않았던 환자는 8명 중 3명(37.5%)으로 VRE 보균자에서 보균율이 더 높았다. 총 64주의 MRSA의 vancomycin MIC의 분포는 0.5-2㎍/mL였으며 2㎍/mL를 초과하는 균주는 발견되지 않았다. 64주 중 vancomycin MIC가 1㎍/mL인 균주가 54주(84.4%)로 가장 많았으며 2㎍/mL 6주(9.4%), 0.5㎍/mL 4주(6.3%)의 순이었다. 결론 : VRE 환자에서 S. aureus의 보균율은 비보균자 보다 높았으며 분리된 균주들은 대부분 MRSA였다. VRSA 균주는 발견되지 않았다. Background : The transfer of vancomycin resistance from vancomycin-resistant enterococci (VRE) to Staphylococcus aureus has been predicted. The purpose of this study is to determine the prevalence and antibiotics resistance of S. aureus among patients colonized with VRE. Methods : Between January 2001 and December 2001, a prospective study was performed at Pusan National University Hospital on 27 patients. Surveillance swabs from nasal cavity, axilla, perineum, and rectum were obtained at weekly intervals. Methicillin susceptability of S. aureus was determined by oxacillin disk diffusion test and minimum inhibitory concentration (MIC) for vancomycin by microdilution broth test. Results : Total of 292 swab cultures were performed and 67 S. aureus isolates were collected. 64 isolates (95.5%) were resistant to methicillin. The prevalence of nasal MRSA carrier in 19 patients colonized with VRE was higher than that in 8 patients not colonized with VRE (58% vs. 37.5%). In 64 MRSA isolates, MIC (㎍/mL) for vancomycin ranged from 0.5 to 2. No isolates with MIC >2 ㎍/mL were observed. MIC of 1 ㎍/mL was shown (observed) in 54 isolates, 2 ㎍/mL in 6 isolates, and 0.5 ㎍/mL in 4 isolates. Conclusion : The prevalence of S. aureus with colonization of VRE is higher than that without colonization of VRE. Most of S. aureus isolates were resistant to methicillin. VRSA isolates were not observed.

      • SCOPUSKCI등재

        Original Article : Geographic difference of epidemiological features of HCV infection in Korea

        ( Kyung Ah Kim ),( Sook Hyang Jeong ),( Eun Sun Jang ),( Young Seok Kim3 ),( Youn Jae Lee ),( Eun Uk Jung ),( In Hee Kim ),( Sung Bum Cho ),( Mee Kyung Kee ),( Chun Kang ) 대한간학회 2014 Clinical and Molecular Hepatology(대한간학회지) Vol.20 No.4

        Background/Aims: The prevalence of hepatitis C virus (HCV) infection in Korea exhibits significant geographic variation, with it being higher in Busan and Jeonam than in other areas. The reason for this intranational geographic difference was investigated in this study by conducting a comparative analysis of the risk factors related to HCV infection among three geographic areas: the capital (Seoul), Busan, and the province of Jeolla. Methods: In total, 990 patients with chronic HCV infection were prospectively enrolled at 5 university hospitals located in Seoul (n=374), Busan (n=264), and Jeolla (n=352). A standardized questionnaire survey on the risk factors for HCV infection was administered to these three groups of patients, and a comparative analysis of the findings was performed. Results: The analysis revealed significant regional differences in exposure to the risk factors of HCV infection. By comparison with patients in Seoul as a control group in the multivariate analysis, patients in Busan had significantly more experience of invasive medical procedures, acupuncture, cosmetic procedures, and multiple sex partners. In contrast, patients in Jeolla were significantly older, and they had a higher prevalence of hepatocellular carcinoma, a lower prevalence of multiple sex partners, and had experienced fewer invasive procedures. Conclusions: There was a significant geographic difference in the exposure to potential risk factors of HCV infection between patients from the three studied regions. This may explain the regional variation of the prevalence of HCV infection in Korea, and should be taken into account when planning strategies for the prevention and management of HCV infection. (Clin Mol Hepatol 2014;20:361-367)

      • SCIESCOPUSKCI등재

        Case Reports : Basal Cell Carcinoma on the Pubic Area: Report of a Case and Review of 19 Korean Cases of BCC from Non-sun-exposed Areas

        ( Jin Park ),( Yong Sun Cho ),( Ki Hun Song ),( Jong Sun Lee ),( Seok Kweon Yun ),( Han Uk Kim ) 대한피부과학회 2011 Annals of Dermatology Vol.23 No.3

        Basal cell carcinoma (BCC) is one of the most commonly diagnosed malignant skin tumors and develops characteristically on sun-exposed areas, such as the head and neck. Ultraviolet light exposure is an important etiologic factor in BCCs, and BCCs arising from non-sun- exposed areas are, therefore, very rare. In particular, the axilla, nipple, the genital and perianal areas are not likely to be exposed to ultraviolet light; thus, if BCC develops in these areas, other predisposing factors should be considered. Herein, we report a case of BCC arising on the pubic area in a 70-year-old man. We also performed a survey of the literature and discussed the 19 cases of BCC from non-sun-exposed areas reported to date in Korea.

      • KCI등재후보

        성희롱 2차 피해의 법적 쟁점과 과제

        장명선,김선욱 이화여자대학교 젠더법학연구소 2016 이화젠더법학 Vol.9 No.3

        최근 우리 사회는 성희롱에 대한 법제가 마련된 지 20년이 지났으나 성희롱 사건이 지속적으로 증가하고 그 사건의 처리과정에서 발생하는 성희롱 2차 피해도 증가하고 있어 성희롱 문제는 중요한 젠더이슈이다. 성희롱 2차 피해는 다양한 유형으로 나타나고 있으나 이에 대한 실태 파악 및 법제가 제대로 마련되어 있지 않은 것이 현실이다. 따라서 본 글에서는 현재 성희롱 2차 피해에 대한 현황을 살펴보고 「남녀고용평등과 일・가정양립 지원에 관한 법률」 제14조제2항에서 규정하고 있는 불리한 조치에 대해 르노삼성자동차 항소심 판결을 중심으로 불리한 조치의 의미, 수범자, 보호대상자, 입증책임, 사업자 책임 등에 대한 내용을 분석하고 한계점을 알아본다. 성희롱 2차 피해를 예방하기 위한 입법과제로서 「남녀고용평등과 일・가정양립 지원에 관한 법률」에 제14조의2를 신설하여 불리한 조치금지에 대한 규정방안을 제시하고 정책과제로서 취업규칙에 성희롱 예방 및 사건처리 규정의 작성, 성희롱 예방교육의 실효성 확보를 위한 방안, 성희롱 사건 처리 시 성인지성 강화, 성희롱 업무담당자 전문성 강화 및 성희롱 업무매뉴얼 보급 등에 대한 방안을 제시한다. Although twenty years have passed since legal systems on sexual harassment were established, sexual harassment has consistently been increasing in society. Moreover, as secondary victimization on sexual harassment has been increasing during handling the cases as well, sexual harassment serves as one of the main gender issues. While there have been various types of secondary victimization on the harassment, investigating current states and redesigning related legal system have not been clearly organized yet. Therefore, the purpose of this study is to identify current states of secondary victimization on the harassment, to analyze content and problems of Section 2 of Article 14 of the Act on Equal Employment and Support for Work-Family Reconciliation, and to analyze meaning of disadvantageous measure, law-addressees, objects of protection, obligation to prove, and liability to investigate limitations, centering on the appellate judgement for the case of Renault Samsung Motors as a recent precedent. This study presented prescription of regulations on banning disadvantageous measures by establishing Section 2 of Article 14 of the Act on Equal Employment and Support for Work-Family Reconciliation as a legislative task to prevent secondary victimization on sexual harassment, while providing measures of prevention of sexual harassment, preparation of regulations on processing the cases, securing effectiveness of sexual harassment prevention education, strengthening gender awareness in handling sexual harassment cases, strengthening professionalism of those who are in charge of such cases, and distribution of work manuals on sexual harassment within regulations related on employment, as policy tasks.

      • KCI등재후보

        지방자치단체의 양성평등기본조례에 관한 연구

        김선욱 이화여자대학교 젠더법학연구소 2016 이화젠더법학 Vol.9 No.3

        The Republic of Korea has consistently attempted to amend laws and to improve the gender inequalities since joining the Convention on the Elimination of All Forms of Discrimination against Women in 1984. As a result, the gender equality of laws and social system was achieved to some extent, but gender discrimination still exists in Korean society. As gender equality is a matter related to the real life, the acts and the policies of the central government are important. But in order to realize gender equality in the lives of local residents, it is very important for local governments to eliminate all institutional and structural factors that cause inequality and to implement concrete policies for an equal order and system. In this article, the Author analyzed the situation of gender equality policy realization in Korean local governments by examining the contents of the regulations and amendments of the ordinances of 17 local governments after the enactment of the “The Framework Act on Gender Equality”, which is a paradigm shift to Gender Mainstreaming of women's policies. In particular, the Author focused how whether the local governments carry out the responsibilities stipulated in the framework act as specific policies, how they take into account the characteristics of the local councils, and whether they have effective promotion systems such as Gender Equality Basic Plans. As a result of the analysis, there are problems with systematic synthesis because some local governments do not stipulate the responsibility of the local government stipulated by The Framework Act on Gender Equality. And, there is a lack of efforts to implement the framework act in accordance with the local government's situation in general. Regardless of the degree of difference in reality, there was little specificity reflecting the local environment, characteristics, and the policy needs of the local residents. So the basic ordinances on gender equality is insufficient in realistic suitability. It is necessary to provide specific regulations to ensure that changes in the paradigm of women's policies, centering on Gender Mainstreaming, can be implemented in policies, organizations and specific administrations. All local governments need to make efforts for self-government legislation to more faithfully define the basic ordinances on gender equality so that the gender equality policies of local government can be realized more specifically, more diversely, and more realistically. 우리나라는 1984년 유엔여성차별철폐협약 가입 이후 성차별적인 법의 개정과 성불평등한 현실을 개선하기 위한 입법적 노력을 꾸준히 시도해왔고 그 성과로 법과 제도상의 평등은 어느 정도 이루어 졌다. 그러나 아직도 사회 각 부분에는 불평등이 많이 남아 있다. 양성평등의 문제는 사회 전 분야의 실생활과 관련되는 문제이므로 국가의 법과 중앙부처의 정책도 중요하지만 지방자치단체들이 그 지역주민들의 삶 속에서 양성평등을 실현하기 위하여 현재 불평등을 야기하는 모든 제도적 구조적 요인을 제거하고 평등한 질서와 시스템을 구현하기 위해 구체적인 정책을 실천하는 것이 매우 중요하다. 따라서 여성정책의 성 주류화로의 패러다임 전환을 담은 「양성평등기본법」 제정 이후 17개 광역지방자치단체 조례의 제・개정상황 및 그 내용 등을 살펴봄으로써 우리나라 지방행정에서의 양성평등정책의 변화 현실을 분석해 보았다. 특히 「양성평등기본법」에서 지자체의 책무로 규정하고 있는 내용을 얼마나 정책적으로 구체화하고 있는지, 지자체의 지역적 특성 등을 고려한 정책적 특별함이 얼마나 있는지, 양성평등기본계획 등 추진체계는 효과적으로 잘 갖추어져 있는지 등을 분석하였다. 지자체별로 약간의 편차는 있으나 「양성평등기본법」에서 규정하고 있는 지자체의 책무를 충실하게 규정하지 않고 있어서 체계적합성에서 문제가 있는 경우도 있고 전체적으로는 기본법을 지자체의 실정에 맞게 구체화하는 노력이 부족하며, 정도의 차이는 있으나 지역의 정책환경이나 특징 그리고 지역주민의 정책요구도를 반영한 특별함이 거의 보이지 않아 현실적합성에도 미흡해 보인다. 특히 성주류화를 중심으로 하는 여성 정책 패러다임의 변화가 정책과 조직과 구체적인 행정에서 행하여질 수 있도록 구체적인 조례의 규정이 필요하다. 모든 지자체는 지자체의 양성평등 정책이 더 구체적으로 더 전문적으로 더 다양하게 실현되어 실질적인 양성평등사회가 구현되는 데 기여할 수 있도록 지자체의 양성평등기본조례를 더 충실하게 규정하는 자치입법의 노력이 필요하다.

      • 생산일정계획에서 Default Rule의 유용성

        김선욱 단국대학교 신소재기술연구소 1994 신소재 Vol.4 No.-

        수립된 생산일정계획은 매우 상세한 과다정보와 시스템에 내재되어 있는 동적인 정보의 특성 때문에 수시로 변경되어질 가능성이 대단히 높다. 더구나 좋은 생산일정계획을 수립하기 위해 최적화방법, 모의실험, 인간-컴퓨터 인터훼이스, 전문가시스템 등이 이용될 수 있으나 실용적이고 현실적인 면에서 많은 문제점을 갖는다. 본 논문에서는 이러한 문제점들이 상세하게 소개되며, 이의 개선을 위한 방안으로 Default rule이 제시된다. Default rule은 모의실험에서 최적으로 판단된 규칙 중 최고의 빈도를 갖는 규칙으로 정의한다. 이 Default rule은 생산성 향상을 보증할 뿐만 아니라 운용면에서도 큰 장점을 갖는다. 한 사례연구에서 30% 이상의 생산성 향상을 보여주었다. It is invitable to modify production schedules very often due to the fact that they require detailed and dynamic information too much in manufacturing systems. Furthermore, there are so many problems to produce good schedules based on optimization methods, simulation, man-computer interface, and expert system. Some limitations and problems on these methods are described in details. A default rule is introduced as a method to reduce these problems. It is a rule which has the highest frequency of the bet rules collected during a simulation. It ensures not only higher productivity but also easy operations of the rule. A case study shows that it turns out to be greater than 30% increase in productivity.

      • KCI등재

        공ㆍ사영역에 대한 법여성학적 고찰

        김선욱 이화여자대학교 한국여성연구원 1996 여성학논집 Vol.13 No.-

        Ⅰ. This paper aims at discussing the public and private split in women's studies issues from the legal perspective. I will examine 1) whether the social function of law makes the division between public and civil laws; 2) whether the law only reflects the reality in which there is a public and private split, and 3) whether the law could improve upon that reality. I will analyze the theory of classification of public and civil laws related to the legal order. I will also examine women's issues arising from the split of public and civil laws. In addition, based on the social functions of law, I will suggest some feminist legal issues which should be addressed, and possible reforms the legal system with regard to the public and private spheres. Ⅱ. Women's lives are lived in the private sector, and are ruled by the civil law, though the law itself does not intend to either include or exclude women. Therefore, I conclude that women's lives and issues have been placed in the private sector, which excludes legal concerns according to the liberalist legal theory. Ⅲ. The interusion of public law into previously private civil matters results from changes in the previous liberalist legal theory, which is based on the principle of a social constitutional state. This principle emphasized the responsibility of the social legal authority for making conditions in which individuals are able to realize the practical freedom to make choices in their lives, as well as formal freedom and equality. For example, if the nation does not intervene in a labor contract via a labor law under the market economy due to its individual nature, that resu1ts in granting the employer the freedom to set the wages of employees rather than improving individual autonomy and freedom. However, because the labor market is a public sector, this kind of problem could be solved with legal remedies, that is the publ1t leglslat1on of previously private civil legal matters. But the intervention of the law related to such issues as domestic labor and violence has not been accomplished, though men's freedom has been strengthened in terms of such issues. Ⅳ. Owing to the convergence of public and civil law, we can establish equal conditions for women by widening legal intervention. Stereotyping gender roles in terms of public and private spheres should be rectified. In other words, by reconstructing the public and private sphere including prohibiting legal intervention in issues such as women's freedom of choice, the improvement of the actual freedom and equality of women can be achieved. Ⅴ. The division of the public and private spheres brings about discrimination against women by strengthening traditional gender roles. In other words, the public and private split limits the choices of women's social roles. As a result, it becomes difficult for women to participate in the public sector. Ⅵ. Women have been excluded from legal fields for a long time because the law itself is assumed to be a public matter. Due to this assumption, women hardly participate in the legal fields. Since it has been men who have made, established, implemented and researched laws, it has been difficult to include women's experiences and points of view. As a result, human beings in laws and legal theories have been defined by male-oriented values. The law and legal theories strongly reflect for the assumptions which delineate different gender roles in a patriarchal society. Ⅶ. The state should intervene to solve women's issues and accomplish equality of genders regardless of where gender discrimination may happen. Regardless to whether the gender discrimination occurs the family, the work places or educational institutions. Actualizing women's rights based on respect and value toward human beings leads to the practical freedom and equality of women. Therefore, the ration should accept the responsibility for actualizing women's rights. On the basis of these values, the public and private spheres in laws can be restructured. Some current private matters can be changed into public ones, and some public issues can be changed into private ones. As a result, the possibilities for solving women's legal issues which have been regulated in the legal arena for a long time can be increased.

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