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      • 감귤과피 물 균질액으로 가공한 유색미의 취반 특성

        서성수,김미향,노홍균,김순동 동아시아식생활학회 2002 동아시아식생활학회지 Vol.12 No.4

        Cooking characteristics of coated rice with water homogenate of citrus fruit peels (1% for rice) were investigated. The color of the coated rice both before and after cooking was dark yellow. The total content of carotenoids, hesperidin and naringin were 10.74, 2173.12 and 1468.40 ㎎% for citrus fruit peels, 0.46, 108.65 and 73.38 ㎎% for its water homogenate, 0.12, 21.73 and 14.62 ㎎% for coated rice, and 0.05, 8.67 and 5.87 ㎎% for cooked coated rice, respectively. Citrus fruits peel contained 94.22 ㎎% of asparagine, 24.88 ㎎% of methionine, 19.64 ㎎% of alaniue, and 15.37 ㎎% of r-aminoisobutyric acid as the majority free amino acids, accounting for 70% of the total free amino acids present. Total free amino acid content of the cooked coated rice increased by 15% compared to those of cooked uncoated rice. The majority of minerals in the citrus fruit peels were K and Ca, accounting for 86% of total minerals present. The mineral content of cooked coated rice was generally higher than that of the cooked uncoated rice. The cooked coated rice showed comparable hardness, gumminess and brittleness, but higher cohesiveness and springiness than the cooked uncoated rice. There were no differences in sweet and bitter taste between the cooked uncoated and coated rice. However, the cooked coated rice showed higher sensory scores for color acceptability, savory taste and overall acceptability than the cooked uncoated rice.

      • 漢方藥劑의 品質評價와 藥效에 關한 硏究(第6報) : 元柴胡및 竹柴胡 水性엑스의 中樞抑制作用에 對하여 Central Depressive Action of Bupleurum Falcatum and Bupleurum Longiradiotum

        徐成勳,洪南斗,權昌鎬,金壽億 慶熙大學校 1988 論文集 Vol.17 No.-

        The effects of the aqueous extracts of Bupleurun falcatum and Bupleurum longiradiotum on the central nervous depressive action were studied by the behaviroral pharmacological method. The roots of Bupleuri radix was extracted with distilled water for 8 hours. Effect of extracts were tested by spontaneous movement activity using photoelectric method, openfield method, sloped plate method, rotarrod method and extension of hypnosis time induced with sodium phenobarbital and pentobarbital sodium, and defense against convulsive action induced with strychnine, picrotoxine and electric shock seizure in mice and rats. Extracts was found to pharmacologically expect above various action similar to these of diazepam but action of samples weaker than that of diazepame. Extracts of Bupleurum longiradiotum was definitely superior to the Bupleurum extracts in the central nervousderpressive action.

      • KCI등재

        수술실 손 소독제의 종류에 따른 균주 수의 변화

        홍성윤,김정민,김소영,이수정,오은실,양서인,김화실,김남초 병원간호사회 2006 임상간호연구 Vol.11 No.2

        Purpose: The present study purposed to compare the hand washing effect of 7.5% powidone-iodine, which is used in the operation room of C university hospital in Seoul, with that of Ethyl alcohol-CHG mixture recommended by the US Association of Operating Room Nurses (2002) and to adopt a more effective hand disinfectant. Method: In a quasi-experimental design, 48 medical staff who participated in operations during the period from November 2004 to February 2005 had hand washing using the two kinds of hand disinfectants: 7.5% povidone-iodine and the ethyl alcohol-CHG mixture. Their palms were swabbed and cultured just after hand washing and again after taking dff sterile gloves after the operation. The number of colonies from the two occasions were counted and compared. Result: The number of general bacillus increased significantly in the group using 7.5% povidone-iodine compared to that in the group using the ethyl alcohol-CHG mixture. The number of general bacillus increased signficantly in doctors compared to that in nurses. The factors affecting the increase of the number of general bacillus were disinfectants and medical personnel. The number of general bacillus was expected to increase 9.41 times with 7.5% povidone-iodine than with the ethyl alcohol-CHG mixture and 14.87 times in doctors than in nurses. Conclusion: This study shows that the ethyl alcogol-CHG mixture has a stronger hand disinfection effect than 7.5% povidone iodine. Thus we need to change the hand disinfectant used in operating rooms as soon as possible in order to minimize the infection of wounds resulting from operations.

      • KCI등재
      • 흡입물질의 위생학적 연구 : 본드 흡입이 흰쥐의 폐 및 기타 장기의 효소 활성에 미치는 영향 The Effect of Bond Inhalation on the Enzyme Activity of Lung and Other Organs in Rat

        윤수홍,박은주,이주영,서혜령 효성여자대학교 부설 한국환경위생연구소 1991 환경위생연구 Vol.1 No.1

        Toluene, alcohol및 vinylester류 등을 함유하고 있는 bond를 이용하여 휘발성 물질이 생체에미치는 영향을 관찰하기 위하여 rat에 일정 농도의 bond를 일정 시간 흡입시킨 뒤 각 조직에대하여 효소의 생화학적 시험과 celluloseacetate electrophoresis를 실시하여 다음과 같은 결과를얻었다. 1. Bond 흡입은 시간이 증가함에 따라 혈청, 심장, 신장, 근육, 뇌의 ChE 활성을 억제하였으며특히 폐와 간장의 ChE활성에 가장 큰 영향을 나타내었다. 2. Bond 흡입에 의해 혈청 및 각 조직 중에서 LDH활성이 증가되었으며 특히 폐와 심장,근육에서 그 영향이 현저히 나타났다. 3. Celluloseacetate electrophoresis를 통한 각 조직의 LDH isozyme pattern에는 차이가 나타났으며 bond 흡입에 의해 band의 소멸과 선명도의 감소가 일어 났는데 특히 폐에 대한 독성이가장 현저했으며 근육에 대한 독성도 큰 것으로 나타났다. Acute poisoning with organic solvents and other volatile compou-nds now usually follows deliberate inhalation(volatile substance abuse) or inges-tion of these compounds. The effect of bond inhalation was analyzed for serum, liver, lung, brain,heart, kidney and muscle. And the observations are revealed on rat cholinesterase activity, lactatedeh-ydrogenase activity and electrophoretic pattern of lactatedehydrogenase isozyme. The results are as follows ; 1. The rat cholinesterase activity on serum, heart, muscle, kidney and brain showthe decrease by increasing of inhalation time of bond, in particular the lungand liver cholinesterase activity was greatly affected. 2. Bond inhalation brough out the lactatedehydrogenase activity increased ofthe serum and the tissues and had an important effect especially in both thelung and muscle lactatedehydrogenase activities. 3. Each tissue was found to have a characteristic distribution of lactatedehydro-genase isozymes on celluloseacetate elelctrophoresis and the development ofinhalation time is shown the disappearence and diffusion of band.

      • KCI등재후보

        Streptococcus constellatus에 의한 경막 외 농양이 동반된 화농성 척추염 1예

        안홍대,박재찬,서종구,김진용,김수연,박윤수,서일혜,조용균 대한감염학회 2008 감염과 화학요법 Vol.40 No.5

        We report a case of vertebral osteomyelitis with epidural abscess caused by Streptococcus constellatus. The patient was present with fever, back pain, and dyspnea for 1 week. The patient was previously healthy and did not have any predisposing factor. After evaluation, the patient was diagnosed as Streptococcus constellatus vertebral osteomyelitis. He was successfully treated with surgical debridement and antibiotic therapy. To the best of our knowledge, this is the first case of S. constellatus vertebral osteomveltis with epidural abscess to be reported in Korea.

      • 택사추출액이 benzo(a)pyrene에 의해 유도된 간장해에 미치는 영향

        尹水弘,徐旼志,河勳 대구효성가톨릭대학교 1996 연구논문집 Vol.52 No.2

        The protective and therapeutic effects of Alismae Rhizome extracts depending on solvent polarity on rat liver injury induced by benzo(a)pyrene were investigated. As parameters in serum and liver, alkaline phosphatase, glutamate oxaloacetate transaminase and glutamate pyruvate transaminase activities were observed. The results were as follows: B(a)P intoxication significantly increased alkaline phosphatase, transaminase activities of serum and liver compared with normal group. Especially CHCI₃fraction revealed the most powerful liver protective and/or therapeutic effect of 4 extracts in serum transaminase activities and in hepatic alkaline phosphatase and glutamate oxaloacetate transaminase, maybe due to presence of alkaloid, triterpenoid and flavonoid in this fraction. Above-mentioned results strongly suggested that Alismae Rhizoma be a promising liver-protective drug. So more study will be needed to find principle hepatotropic Alismatis Rhizoma.

      • Benzo(a) pyrene에 의해 유도된 간장해에 미치는 황련 수침액의 영향

        윤수홍,하헌,서민지 한국환경독성학회 1993 환경독성보건학회지 Vol.8 No.1

        The present study was undertaken to find a protective effect of Coptis Rhizoma Extract on liver injury induced by benzo (a)pyrene in rats. This crude drug significantly suppressed the increase of several biochemical parameters such as transaminase, lactate dehydrogenase and alkaline phosphatase in serum and liver and total cholesterol. But there were little changes in elevated serum phospholipid level. The results suggested that Coptis Rhizoma prevent bezo (a)pyrene-induced hepatic injury.

      • KCI등재후보

        고혈압·당뇨병 신규 환자 발견 이후 지역사회 협력을 통한 등록관리가 치료순응도 및 혈압 및 혈당 조절에 미치는 영향

        홍두호(Duho Hong),서화정(Hwa-jeong Seo),강경희(Kyoung-hee Kang),김은주(Eun-ju Kim),임정수(Jeong-Soo Im),오대규(Dae-kyu Oh),임준(Jun Yim) 한국농촌의학 지역보건학회 2008 농촌의학·지역보건 Vol.33 No.3

        인천광역시의 2개 지방자치단체에서 고혈압과 당뇨병의 관리를 위해 민간의료기관과 함께 만든 만성질환등록관리체계의 효과를 평가하였다. 만성질환등록관리체계에 등록관리가 이루어지고 있는 군이 미등록군에 비해 치료순응도와 혈압 및 혈당의 조절 정도가 좋은지를 평가하였다. 자료분석은 로짓회귀모형을 구축하여 이루어졌고, 다단계 변수 선택법을 사용하여 교차비와 95% 신뢰구간을 구하였다. 연구결과 등록관리군이 미등록군에 비해 치료순응도가 5.5배 높았고, 혈압 및 혈당의 조절이 3.78배 더 잘 되었다. 향후 이러한 효과가 인천광역시 전체 사업으로 확대된 후에도 지속되는지를 평가할 필요가 있다. Objectives : Incheon metropolitan city has set a model program of community partnership for hypertensive or diabetic patients detection and follow-up since 2005. This study examines the effects of the model on the compliance and the control of blood pressure or blood sugar level Methods : Telephone-surveys were done for 140 persons selected from 408 patients who were detected newly as hypertensive or diabetic patients at Gangwha-Gun and Seo-Gu in Incheon between January 1st and August 31th in 2006, and finally completed in 110 patients(78.6%). Survey questionnaires included socio-demographic(age, gender, and educational level), health behavioral (smoking, drinking, physical activity, and diet), and therapy-related (registration state, compliance, blood pressure or blood sugar control) variables. Odds ratio and 95% CI were derived from logistic regression model. Results : Registered group exhibited high compliance and well managed blood pressure or blood sugar level. The odds ratio of registration were 5.55(95% CI:1.83~16.89) for compliance and 3.78(95% CI:1.43~9.99) for blood pressure or blood sugar control after adjusting for age, gender, disease, and area Conclusions : It is independently related to compliance and blood pressure or blood sugar control whether the patient is registered or not. To control hypertension or diabetes mellitus in terms of compliance and control state, a community-based registration program through community partnership could be a powerful tool.

      • 개심술(開心術)의 임상적 고찰 : 치험 200예 200 Cases

        최형호,서홍주,임영혁,김정중,배대양,이석기,임진수 조선대학교 부설 의학연구소 2002 The Medical Journal of Chosun University Vol.27 No.2

        Background and Objectives: Two hundred cases of the open heart surgery due to congenital and acquired heart disease were done using the cardiopulmonary bypass in the Department of Thoracic and Cardiovascular surgery, Chosun University Hospital from November, 1980 to June, 2001. Material and Methods: The number of congenital heart disease was 132 cases. 68 cases were acquired heart disease. 'The age of the congenital heart disease was from 22 days to 45 years. In the acquired heart disease, the age was from 14 to 72 years. Result: Congenital heart disease consisted of 113 congenital acyanotic heart disease, 19 congenital cyanotic heart disease. Corrective operation was done for congenital heart disease with 4. 5 % operative mortality. Of 68 cases acquired heart disease, 44 patients were valvular heart disease, 3 cardiac tumors, 9 ischemic heart diseases, 12 aortic dissections and etc. The operative mortality was 13%. Conclusion: The postoperative complications were appeared in 68 cases and the complications were wound infection, occipital alopecia, low cardiac output syndrome, arrhythmia, septicemia etc. The mortality after open heart surgery was 15 cases and the causes of death were low cardiac output syndrome, septicemia, respiratory failure and left ventricle rupture.

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