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      • 석면함유 슬레이트 지붕 물받이 퇴적물 중 석면 섬유 함유율

        임지현,한솔민,김현석,신유민,박시은,허정윤,김민영,장봉기 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

        This study attempted to determine the degree of asbestos release from the aging slate roof by comparing the asbestos content in the slate roof rain gutter with a colored steel plate (tin plate) over the slate roof. Four slate roof houses located in Haengmok-ri, Asan-si, Chungcheongnam-do, and one house constructed with a colored steel plate on the slate roof were selected to collect the sediment of the roof rain gutter. The asbestos fiber content was calculated by a point counting method using a polarization microscope after pretreatment with conversion treatment and hydrochloric acid treatment. The average asbestos content of the four slate roof rain gutter were 1.89%. However, asbestos was not detected in the Slate covering roof rain gutter, which were constructed on the slate roof. Asbestos fiber content was the highest at 2.89% in the slate roof rain gutter installed in 1976, followed by 2.44% in 1953. From the above results, it is necessary to minimize secondary damage as asbestos fibers released from slate roof houses to the surrounding atmosphere or leaked from slate roofs as rainwater may cause soil pollution and seriously affect residents' health. Although covering with colored steel plates (tin plates) has been shown to prevent the leakage of asbestos fibers to some extent, it is believed that a policy alternative to remove the slate roof as soon as possible is needed to solve the fundamental problem.

      • KCI등재

        Frailty and Disability in Diabetes

        Sol-Ji Yoon,김광일 대한노인병학회 2019 Annals of geriatric medicine and research Vol.23 No.4

        Diabetes is an important health problem with the population aging. Previously, it is well established that diabetes is associated with microvascular and macrovascular complication, but recently, several data suggests that diabetes is accompanied with frailty as well as disability among the older adults. Considering the clinical significance of frailty and disability, it is important to understand the pathway from diabetes to frailty and/or disability. Additionally, it is strongly recommended to find a new therapeutic intervention are required to meet the increasing demand of managing older diabetic patient with the population aging.

      • S-735 Socioeconomic status is associated with frailty in Korean old adults: Data from KHANES

        ( Sol-ji Yoon ),( Jung-yeon Choi ),( Min-gu Kang ),( Sun-wook Kim ),( Cheol-ho Kim ),( Kwang-il Kim ) 대한내과학회 2016 대한내과학회 추계학술발표논문집 Vol.2016 No.1

        Background:?Low Socioeconomic status (SES) is a common risk factor of poor health in older adults. Frailty is also a common risk factor for morbidity and mortality in older adults. Although the existence of a social gradient in the frail elderly is known previously, there are no studies how SES affects the health status of the frail elderly. This study aims to examine the relationship between SES and frailty and analyze how SES affects frailty in Korean older adults.?Methods:?This study use the data from Korean Health and Nutritional Examination Survey (KHANES). It is a cross-sectional population study and designed to assess the health related behavior, health condition, and nutritional state of Korean. Of 4557 participants (≥ 65 years) in 6th cycle KHANES (2010-2012), excluding of 1,268 who were not answered parents’ educational level, we analyzed 3,289 participants. We used the frailty index using 41 deficits in the data. The relationships between difference indicators of SES and frailty were assessed in multivariable logistic regression models adjusted for potential confounders.?Results:?Of the samples, 1,199(36.4%) were robust, 1,112(33.8%) were prefrail and 978(29.7) were frail. In adjusted models, low level of education was associated with frailty (odd ratio [OR]: 3.16, 95% confidence interval [CI]: 2.40-4.54). Frailty also related with low level of occupation during midlife (OR: 2.97, CI: 2.00-4.38) and poor financial security (OR: 1.79, 95% CI: 1.48-2.16). The education/occupation level and marital status were related to health behaviors like smoking, drinking and irregular hospital visit (p<0.001).Conclusions:?The odds of frailty are increased as lower education/occupation level and unmarried/divorced/widowed status. The education/occupation level and marital status are related to health behavior, which may influence on glucose and BP control.

      • S-732 Practical Application of Fall Prevention Guideline in Community-dwelling Elderly

        ( Sol-ji Yoon ),( Jung-yeon Choi ),( Min-gu Kang ),( Sun-wook Kim ),( Cheol-ho Kim ),( Kwang-il Kim ) 대한내과학회 2016 대한내과학회 추계학술발표논문집 Vol.2016 No.1

        Background:?Fall is one of the most important causes of injury in the elderly and it triggers calamitous consequence in independence of daily living, and quality of life. The Korean Association of Internal Medicine and the Korean Geriatric Society developed evidence-based guideline for fall prevention and release conjointly. This study aim to analyze the results of fall risk assessment and examine the effects of structured physical activity program in the community-dwelling elderly based on the guideline.?Methods:?We registered community dwelling older persons (≥65 years) who live in Seongnam-si between April and May 2016. 29 participants were enrolled from Seongnam home visiting program, 23 were enrolled from daycare program in Seongnam central welfare center and 12 were recruited through announcements in the welfare center. All participants examined multidimensional fall risk assessment including the initial physical performance test and frailty assessment. They joined moderated-intensity physical activity program conducted in a welfare center or at home 2 times per week over 4 weeks. After 4 weeks of physical intervention, we followed up the physical performance test.?Results:?Participants of home visiting group and daycare program group were more frail than welfare recruitment group, but not statistically significant (Home visiting program group: Robust 24.1%, Pre-frail: 44.8%, Frail: 31.0%; daycare program group: 47.8%, 34.8%, 17.4%; welfare recruitment group: 50.0%, 41.7%, 8.3%, p=0.088). After 4 weeks physical activity program, grip strength was significant improved in home visiting group and daycare program group (12.0±4.8 vs 15.8±5.3, 12.7 ±5.8 vs 16.1±6.4, p<0.001, p=0.004). POMA score was improved in home visiting group (22.9±5.9 vs 24.3±5.2, p=0.019). But welfare recruitment group and daycare program group showed no improvement (28.0 vs 28.0, 26.4±3.1 vs 25.4±3.8, p=0.173).?Conclusions:?A structured physical activity program improved physical performance in the elderly over 1 month. It especially effected on home visiting group. This finding suggests that mobility have more benefits from such a program in vulnerable older adults.

      • SCISCIESCOPUS
      • A Case of Gastric Candidiasis in the frail elderly patient

        ( Sol-ji Yoon ),( Jung-yeon Choi ),( Min-gu Kang ),( Sun-wook Kim ),( Cheol-ho Kim ),( Kwang-il Kim ) 대한내과학회 2015 대한내과학회 추계학술발표논문집 Vol.2015 No.1

        Background: Gastrointestinal tract candidiasis is not unusual but has most often been reported in immunocompromised patients. Esophagus is most frequently involved in gastrointestinal tract candidiasis, but gastric involvement has been noted in rare instances, especially primary infection of the mucosa, uncompromised patients. Case Presentation: We experienced a case of gastric candidiasis in an 83-year-old female with diabetes mellitus, hypertension, coronary heart disease, and disability. She underwent left upper lobe lingular segmentectomy by hybrid video-assisted thoracoscopic surgery for lung cancer and finally diagnosed as an adenocarcinoma, T1aN0M0, stage IA. On the 3rd day after surgery, the patient had epigastric discomfort and melena. Endoscopic findings revealed whitish ulcerative lesion in cardia and fundus of the stomach. Pathologic findings revealed budding yeast and pseudohyphae infiltrating through the ulcerated stomach wall. After the patient had been treated with fluconazole 200 mg daily for 20 days, symptoms were improved. Conclusions: This case suggest that frailty is associated with immune dysregulation, so frail elderly patient could have opportunistic infection like gastric candidiasis

      • Poster Session : PS 0292 ; Geriatrics : Interactive Effects of Age and 24-Hour Blood Pressure Variability on Left Ventricular Hypertrophy; Data from the Korean Ambulatory Blood Pressure (KOR-ABP) Registry

        ( Sol Ji Yoon ),( Hee Won Jung ),( Sun Wook Kim ),( Jung Yeon Choi ),( Kwang Il Kim ),( Cheol Ho Kim ) 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1

        Introduction: Increased short-term blood pressure variability (BPV) has been known to be related with target organ damages independent of blood pressure (BP) level. However, the effect of age on the relationship between BPV and left ventricular hypertrophy (LVH) has not been evaluated. We aimed to investigate the relationships between age, BPV, and LVH in a cross sectional study. Methods: Among the 3, 762 participants of the Korean ambulatory BP (KOR-ABP) registry, we assessed the data of 1, 606 (42. 7%) participants who had the record of echocardiography. As an index for 24-hour BPV, the average real variability (ARV) of systolic and diastolic BP was analyzed. We used left ventricular mass index (LVMI, LV mass divided by body surface area) as an index for LVH (LVH; > 95 g/m2 in women, > 115 g/m2 in men). Results: Mean age was 57. 2 (SD 14. 2) years, 857 (53. 4%) were men, and 953 (59. 3%) had hypertension (BP >140/90 mmHg or taking antihypertensive medications). Age was not associated with 24-hour average systolic BP (B=0. 037, P=0. 211), but associated with 24-hour average diastolic BP (B=-0. 18, P<0. 001) by linear regression analysis. However, age was associated with both 24-hour ARV of systolic (B=0. 06, P<0. 001) and diastolic (B=0. 03, P=0. 014) BP. There were signifi cant relationships of age and BPV on the presence of LVH, thus the older participants with increased BPV showed higher risk of having LVH. (figure) Conclusion: In KOR-ABP registry, age was associated with short-term BPV. Furthermore, there exist significant interactive effects of age and BPV on left ventricular hypertrophy.

      • KCI등재

        GV16 acupoint stimulation with bee venom reduces peripheral hypersensitivity via activation of α2 adrenoceptors in a nitroglycerin-induced migraine mouse model

        Sol-Ji Kim,Ji-Hee Yeo,Seo-Yeon Yoon,Dae-Hyun Roh 한국한의학연구원 2023 Integrative Medicine Research Vol.12 No.4

        Background: Peripheral hypersensitivities develop in the face and hindpaws of mice with nitroglycerin (NTG)-induced migraine. We evaluated whether diluted bee venom (DBV) injections at acupoints prevented these peripheral hypersensitivities and c-Fos expression in the trigeminal nucleus caudalis (TNC). Methods: NTG (10 mg/kg, intraperitoneal, i.p.) was administered every other day for nine days. DBV (0.1 mg/kg) was subcutaneously injected into the ST36 (Zusanli), LI4 (Hegu), or GV16 (Fengfu) acupoints 75 min after each NTG injection. Mice were pretreated with naloxone (5 mg/kg, i.p.) or yohimbine (5 mg/kg, i.p.) 30 min before the DBV injections. Results: NTG injection caused facial cold allodynia, hindpaw mechanical allodynia, and increased c-Fos-immunoreactive (ir) cells in the TNC. Repetitive DBV injections at GV16, but not the ST36, or LI4 acupoints, suppressed NTG-induced hindpaw mechanical allodynia and facial cold allodynia. The number of c-Fos-ir cells also decreased in response to DBV injections at the GV16 acupoint. Remarkably, pretreatment with yohimbine reversed the anti-allodynic effects of DBV injections and attenuated the decreased c-Fos expression in response to GV16 DBV treatment. Naloxone did not block the effects of GV16 DBV stimulation. Conclusion: These findings demonstrate that repetitive DBV treatment at the GV16 acupoint relieves NTG-induced facial and hindpaw hypersensitivities and decreases in c-Fos expression in the TNC via activation of the alpha-2 adrenoceptors, but not the opioid receptors.

      • SCOPUSKCI등재

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