비만증 환자에서 한약제에 의한 체중 감소효과

Oh, Seung-Joon,Jeong, In-Kyung,Kim, Young-Seol,Choi, Young-Kil,Paeng, Jeong-Ryung,Bae, Jung-Hwan,Shin, Hyun-Dae 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Seung-Joon Oh, In-Kyung Jeong, Young-Seol Kim, Young-Kil Choi, Jeong-Ryung Paeng¹, Jung-Hwan Bae and Hyun-Dae Shin²Department of internal Medicine, College Medicine, Endocrine Research Institute¹. Department of Rehabilitation, College of Oriental Medicine², Seoul, korea. Bady Fat Reduction Effects of Red Ginseng Compound Preparation on the Patients with Obesity. Proceedings of International Symposium on East-West Medicine, Seoul. 244-254, 1999.-Obesity can be defined as a metabolic disease due to an increased state of fat tissues caused by an imbalance of calorie intake and use. Recently, in Korea by improvement and westernization of food intake, along with decrease in exercise activities, the prevalence of obesity has increased greatly. Our objectives were to study stability and effects of decrease in body fat by administering red ginseng compound preparation (known to have body fat decreasing effects in laboratory animals) to obesity patients on low calorie diets. Changes in weight and body fat were measured while carrying out calorie-restricted diets on patients for 4 weeks, then administering red ginseng compound preparation for another 4 weeks. The patients were 20 people whose BMI were 25kg/㎡ or over and whose percent body fat was also 30% or over when tested by bioelectrical conductivity. 1. Changes in weight were from 70.04kg(base line) to 67.43kg(after taking red ginseng compound preparation). 2. In similar sense, BMI decreased from 27.12kg/㎡(base line) to 26.56kg/㎡(after dieting), and further to 26.01kg/㎡ (after taking red ginseng compound preparation). The BMI seemed to decrease significantly compared to the baseline after the use of red ginseng compound. 3. Waist hip ratio was changed from 0.8858(base line) to 0.8728, but it was statistically insignificant. 4. The percent body fat was 35,16%(base line), 33.87%(after dieting), and 31.68%(after taking red ginseng compound preparation). 5. Complete blood cell count and blood chemisrty remained unaffected by the administration. 6. In concern to endocrinologic studies, T3 decreased from 118.7 to 98.2ng/dL, and T4 increased from 8.8 to 9.2㎕/ dL. Epinephrine showed a tendency to decreased from 0.27 to 0.25 ng/mL, and norepinephrine increased from 0.39 to 0.44ng/mL. 7. Leptin was not changed. 8. Some patients complained adverse effects; constipation(5 patients, may be due to diet therapy), fatigue (2 patients), pruritus(2 patients), flushing(s patients), dizziness(3 patients) and epigastric discomfort(2 patients). However their symptoms were mild, so medication did not stopped. In conclusion, loss of weight without significant side effects was observed during low calorie diet and red ginseng compound preparation administration. This is thought to be in relation to sympathetic nerve system rather than adrenal gland. Also, further long0term studies should be required, since the observed results were based on short-term changes in weight.

GMAHN 환경에서의 TCP 프로토콜 성능 분석

吳世德,金玄旭,李光培,張良根,裵振勝,金在浩 明知大學校 産業技術硏究所 2007 産業技術硏究所論文集 Vol.26 No.-

Recently, GMAHN that provides interface between MANET and Wired Network has been focused in Mobile Communication. It is necessary that The technology provide reliable data transmission technology between mobile node and wired network in MANET environment that varing by the node movement. In this paper, using the TCP protocol(Tahoe, Reno, Vegas, SACK)that increases reliability between source and destination, we applied the TCP protocol mechanism to various environment, and compared result, and also proposed the efficient TCP mechanism by comparing each mechanism.

공공기관 엔터프라이즈아키텍처 성숙도 측정을 통한 정책 시사점 연구

오승운,박현우 한국정보사회진흥원 2008 정보화정책 Vol.15 No.4

정보화 발전과 함께 정보시스템의 투자규모가 확대됨에 따라 중복투자가 발생하고 시스템 간 연계가 복잡하게 되면서 이를 해결할 수 있는 수단이 필요하게 되었다. 이로 인해 엔터프라이즈아키텍처(EA) 도입 및 활용이 의무화 되었다. 더불어 EA의 지속적인 발전 및 고도화 방향 설정을 하기 위한 도구로 범정부 EA 통합 성숙도 모델 v2.0이 개발되었다. 공공기관 성숙도 측정 결과는 2006년 및 2007년 자료를 활용하였으며 2006년 자료는 개별기관의 EA 도입계획을 분석하였고 2007년은 EA 실태조사 및 성숙도 측정 결과를 분석하였다. 연구결과 공공기관 성숙도 수준은 전체 영역 평균 2.0 수준으로 관리영역은 2단계인 정의 수준, 수립 영역은 2단계인 기준수립 수준, 활용 영역은 1단계인 인식 수준이며 국내는 아직까지 EA 활용을 통한 성과를 얻기에는 아직 이른 시점으로 분석되었다. 본 연구는 국내 EA 성숙도 측정을 통한 정책시사점을 얻기 위한 연구로 이를 위해 선진국가의 EA 성숙도 모델 및 측정 제도를 연구하고 국내 EA 성숙도 측정 결과를 분석하였다. 그 결과 국내 EA 성숙도 측정 제도와 공공기관의 EA 현 수준의 문제점 및 개선방향 제시가 이 연구의 목적이다. The size of investment in information systems is magnified along with informatization development. Expenditures are frequently sourced from many different uncoordinated budgets, resulting in significant duplication, redundancy as well as conflict in the demand for resources. As a result of these problems, the introduction and management of Enterprise Architecture (hereinafter referred to as "EA") in organizations has been mandated by law in Korea. The data from 2006 and 2007 has been applied to the public agency maturity assessment results. The 2006 data was used in analyzing EA introduction plans of the individual agencies, and the 2007 data was used in maturity assessment results as well as the actual conditions of EA. Research results of the public agency maturity level showed an overall average level of 2.0: Level 2 (Definition Level) in the Management Area, Level 2 (Baseline Establishment Level) in the Establishment Area, and Level 1(Recognition Level) in the Use Area. The results reflect that achieving performance from EA use is still too early to calculate. The purpose of this study is to get the current political implications on EA via the assessment of domestic EA maturity. For this, we analyzed the domestic EA maturity assessment results and studied maturity models and EA assessment systems of other advanced countries. By using these results, the aim of this research is to recognize the problems and to suggest some directions for improvement of domestic EA maturity assessment systems and the current levels of public agency EA.

기관골 신생증 1예

오영상,이은우,정종혁,문승원,김수현,김동한,양혁승,박정환,박경옥,강성수,이영직 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

Tracheobronchopathia osteoplastica is a rare disorder of unknown cause characterized by the projection of numerous bony or cartilaginous submucosal nodules into the tracheobronchial lumen with sparing of the posterior membranous portion of tracheobronchial tree. In the past, most of the cases were diagnosed as secondary finding at autopsy. Nowaday, the key component of the evaluation is flexible fiberoptic laryngoscopy and bronchoscopy, which typically demonstrates irregular spicules of subrnucosal bone and cartilage projecting into the tracheobronchial lumen and causing various degrees of airway obstruction. A 45 years old man was visited Sunchon St. Carollo hospital due to discomfort on throat. We saw several nodules just below vocal cord via laryngoscope. The computed tomography revealed multiple small calcified nqdules on trachea and both main bronchi. Pathologic finding of bronchoscopic biopsy showed abnormal proliferation of bony and cartilagious nodules in the tracheal submucosa. These fingdings were consistent with tracheobronchopathia osteoplastica. We report here on a case of tracheobronchopathia osteoplastica with review of literature.

Plasmid DNA pBR 322의 증폭과 Hydroxyapatite Chromatography에 의한 분리

오두환,유주현,신원철,정건섭,유승구 연세대학교 산업기술연구소 1984 논문집 Vol.16 No.1

The amplification and the isolation conditions of pBR322 plasmid DNA were investigated. For the amplification of pBR322 plasmid DNA, cells from logarithmic growth phase were most effective. The optimal conditions for the amplification of pBR322 plasmid DNA in Escherichia coli GM4 were obtained as follows; 50-150 ㎍/ml of chloramphenicol concentration, 6-8 hours of incubation time in the presence of chloramphenicol. Ampicillin and tetracycline had no effect on the amplification of pBR322 plasmid DNA. Approximately 1 mg of pBR322 plasmid DNA was purified from 3.5 ℓof Escherichia coli GM4 culture broth by hydroxyapatite chromatography. The purified pBR322 plasmid DNA was expressed in Escherichia coli C600.

외부 프리스트레스트 콘크리트 보의 휨강도 산정을 위한 근사계산 방법

오승현,강원호 東亞大學校 建設技術硏究所 2008 硏究論文集 Vol.32 No.1

Since externally prestressed concrete structures have visible profile of prestressing steel, it has advantage of maintenance to investigate and to re-tension the prestressing steel in service state. The flexural moment capacity of extetnally prestressed concrete members can be calculated by the analysis of internally statically indeterminate members, which is different from internally prestressed concrete members. Therefore, it needs nonlinear analysis considering complex ultimate state behavior after cracking. While most of the design codes and empirical formulas proposed approximate methods of calculation based on test results, it is only possible to apply them for the same condition as test specimens. Since they have problems of poor theoretical ground for influencing parameters, it is difficult to apply them for the calculation of flexural moment capacity for arbitrary conditions of tendon profiles. To reduce the discrepancy between accurate analysis and empirical formulas, many experiments and studies are continued. In this study, we proposed an approximate method to calculate the flexural moment capacity of prestressed concrete members with extemal tendons through sectional analysis considering internal indeterminacy. In order to examine not only the proposed method but also the design codes, we carried out beam test, which includes two simple beams of various external tendon profiles. The proposed method shows better agreements than the design specifications.

조기위함에서 침윤, 유형 및 분화도에 따른 p53, bcl-2의 발현

권오선,조현득,오미혜,김의한,양승하 순천향대학교 의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.2

..

모 제약회사 근로자들의 직업성 천식 유병률과 약제 분말 노출수준

오성수,최용휴,김은아,이영목,장재길,유장진,박승현,김태균,정수영,김규상,강성규 大韓産業醫學會 2006 대한직업환경의학회지 Vol.18 No.2

목적: 제약회사에서 직업상 천식의 유병 규모를 파악하고 작업공정에 대한 작업환경 측정을 통해 제약회사의 약제 분말에 대한 노출수준을 평가하고자 하였다. 방법: 제약회사에서 약제 분말에 노출되는 근로자를 대상으로 천식을 선별하기 위하여 설문조사 및 진찰, 혈액검사, 폐기능 검사 그리고 피부단자시험을 실시하였고, 각 부서별 공정에 따라서 총분진과 항생제 또는 효소제 분말에 대한 작업환경 측정을 실시하였다. 직업상 천식이 의심되는 근로자에 대하여 기관지과민성에 대한 검사(메타콜린을 이용한 비특이 기관지유발시험)와 약제 분말 기관지유발시험을 실시하여 확진하였다. 결과: 설문조사 및 진찰에서 작업 관련 천식 증상이 있는 근로자는 11명(34.4%)이었고, 약제 분말을 이용한 피부단자시험에서 1+ 이상 반응을 보인 근로자 10명(31.2%)이었다. 비특이 기관지유발시험 결과 8명(25.0%)이 양성(PC20 ≤16 mg/ml)이었다. 약제 분말 기관지유발시험을 통해 직업상 천식으로 확진된 근로자는 5명(15.6%)이었다. 작업환경 측정에서 원료를 충진하거나 투입하는 작업 그리고 정립작업에서 약제 분말에 대한 노출이 많았다. 결론: 제약회사에서 직업상 천식은 주로 제조공정 중 약제 분말에 노출된 근로자에서 발생하여, 증상 및 직업성 천식의 유병률이 높았다. 따라서 원료를 충진 또는 투입하는 작업과 정립작업 등 제조과적에서 약제 분말 노출을 줄이기 위한 세심한 주의가 필요하여, 약제 분말을 취급하는 근로자에 대해서는 천식 증상 조사뿐 아니라 정기적으로 피부단자시험, 비특이 기관지유발시험 등을 실시하여야 할 것이다. Objectives: After the investigation of one worker with occupational asthma, we surveyed the preva- lence of occupational asthma and the exposure level of pharmaceutical dust of 32 workers in a pharmaceutical company. Methods: Thirty-two of the 90 employees participated in the survey which consisted of questionnaire, blood sampling, spirometry and skin prick tests with 8 common allergens as well as 9 antibiotics and 2 enzymes. Various indices of the working environment were also measured. Subjects who had a symptom suggestive of work-related asthma or positive skin prick test were further investigated by PC20 methacholine. Nine subjects who had a PC20 result of 16 mg/ml or less (n=7) or had work-related symptoms and positive skin prick test (n=2) were referred to undergo a specific bronchial provocation test to phar- maceutical dust in an academic allergic disease center. Results: Eleven of 32 workers (34.4%) had a work-related symptom suggestive of occupational asthma. Ten (31.2%) showed positive skin prick test. 8 (25.0%) had a PC20 result of 16 mg/ml or less (indicative of significant bronchial hyperresponsiveness), and 5 (15.6%) had a positive result on the specific bronchial provocation test. Exposure levels of stuffing, input of raw materials and screening process were relatively high. Conclusions: This survey showed that pharmaceutical workers have an increased risk of occupational asthma. Although pharmaceutical factories maintain a relatively good working environment, careful control of respiratory tract exposures, especially during stuffing, input or raw materials and screening process, is important to prevent occupational asthma. Pharmaceutical workers need to undergo regular skin prick and methacholine bronchial provocation tests, as well as asthmatic symptom survey, to ensure the early detection and prevention of occupational asthma.

라즈베리파이와 아두이노를 활용한 캠핑 멀티 박스

김종현,오제용,함승수,이재건,이순흠 순천향대학교 부설 산업기술연구소 2021 순천향 산업기술연구소논문집 Vol.27 No.2

There is a rising hobby in the COVID-19 pandemic era. At this point, camping accidents are also occurring a lot as more people are camping in cars and outdoors. Most of the casualties among them are carbon monoxide poisoning accidents. Therefore, to prevent carbon monoxide poisoning, we measured with an Arduino board using a "DHT22" sensor and an "MQ7" sensor to know temperature, humidity, and carbon monoxide levels, and then printed it out on LCD after storing it in Raspberry Pi database. Therefore, it is implemented through 3D printing on the appearance modeled directly to the actual user.

꽃송이버섯 균사배양적 특성

장현유,최승오 한국버섯학회 2004 한국버섯학회지 Vol.2 No.3

꽃송이는 약산성인 pH 5에서 생장이 가장 빠르다. 꽃송이는 MEF배지에서 가장 잘 자란다. 다음은 MES, MEI, YMF, YMM, YMT, YMB, YMI, MEA, PDA순으로 잘 자랐다. 꽃송이버섯은 종합미네랄을 0.2% 첨가하였을때 균사생장이 가장 좋았고, 0.2%보다 많거나 적을 경우 균사생장이 약해진다. 꽃송이버섯의 생육에는 무기염류(minerals)로서 P, K, N, S등이 비교적 다량(약 100~500mg/)으로 요구되며 그외에도 미량원소로서 Fe, Zn, Cu, Mo, Co, Mn, Cl등이 필요하다. 꽃송이버섯은 비오틴을 0.1% 첨가시 균사생장이 가장 좋았고 이보다 많거나 적을 경우 균사생장이 약해진다. 꽃송이버섯은 티아민을 0.1% 첨가시 균사생장이 가장 좋았고 이보다 많거나 적을 경우 균사생장이 약해진다. 꽃송이버섯은 Fructose을 2% 첨가시 균사생장이 가장 좋았고 이보다 많거나 적을 경우 균사생장이 약해진다. It shows that there is the fastest growth of S. crispa in the weak acid pH5. Also, it shows that S. crispa has the best environment in the MEF media. The next desirable one was as in this array: MES, MEI, YMF, YMM, YMT, YMB, YMI, MEA, PDA. The best fungi-growth of S. crispa is shown within the 0.2% addition of multi-mineral. The slow fungi-growth of S. crispa is shown within as the opposite. The phisical growth of S. crispa has a absolute need of comparatably large amount of P,K,N,S etc as inorganic minerals. In addition of that, as a minor element, Fe, Zn, Cu, Mo, Co, Mn, Cl etc are should be included. The best fungi-growth of S. crispa is shown within the 0.1% addition of biotin. The slow fungi-growth of S. crispa is shown within as the opposite. The best fungi-growth of S. crispa is shown within the 2% addition of fructose. The slow fungi-growth of S. crispa is shown within as the opposite.