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RISS 인기검색어
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- 저자 : ( Mudassar Iqbal Arain ) (검색결과 1 건)
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( Mudassar Iqbal Arain ),( Saira Shahnaz ),( Ramesha Anwar ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-
Purpose Post marketing study is an ongoing process. In developed countries, it is one of most neglected phase of clinical trial. The current study was specially designed to assess the adverse drug reaction (ADRs) of Oral Salbutamol in chronic asthmatic patients at different clinical setups of Hyderabad, Pakistan. Methodology A cross-sectional study was conducted among 254 chronic asthmatic patients via purposive sampling method. The sample size was calculated on the basis of 5% of prevalence rate. Only those patients were enrolled who are on oral salbutamol (2 and 4mg Tablets). The confidence interval was 95%. The patients were enrolled from 10 different private clinical setups of Hyderabad, Pakistan. The data were analyzed using WHO assessment scale. Results Out of 254 patients, first group i.e. 154 patients were taken 2mg tablets and second group i.e.100 patients were on 4mg. Maximum ADRs were reported from second group i.e. 32 patients had developed various adverse reactions from minor to moderate. While 21 patients from first group had different adverse drug reactions. The most common ADRs were headache as minor ADR while tachycardia and arrhythmias were also reported as moderate ADRs. Mostly ADRs were reported in female as compared to male gender. The p value is less than 0.05. Based on WHO assessment scale, mostly ADRs were categorized in probable scale. Conclusion The Results revealed that on 4mg Salbutamol maximum number of ADRs were reported. There should be more focus to describe the underlying causes. Proper training will be utmost importance on reporting and dosing guidelines.
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