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상부요로계감염 환자에서 Gallium-67 Citrate 스캔 및 Tc-99m Dimercaptosuccinic Acid(DMSA)스캔의 임상적 의의
이강욱,강민규,장윤경,양종오,이상주,박기현,소영,신영태 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.2
It is often not certain whether the focal defect of renal cortex of Tc-99m Dimercaptosuccinic acid(DMSA) renal scan in patients with acute pyelonephritis means the cortical scar by previous inflammation or recent active inflammatory lesion. Gallium-67 citrate(Ga-67) also has been known to be accumulated at the active inflammatory lesion. In order to evaluate the usefulness of the Ga67 and Tc-99m DMSA renal scan in patients with acute pyelonephritis, we reviewed the results of both study and clinical findings. Nintecn patients with typical clinical findings of acute pyelonephritis and admitted to our institute from Jan. 1998 to Nov. 1998 were included in this study. Tc-99m DMSA and Ga-67 scan were performed mean 3.3 and 7.3 days after admission. Eleven of 19 patients (57.9%) showed abnormally increased focal renal uptake on the Gallium-67 citrate scan and 14 of 19 patients(73.7%) had a cortical defect on the kidneys in Tc-99m DMSA scan. Seven(36.8%) patients had an abnormality in both study. Seven(36.8%) patients had an abnormality only in Tc-99m DMSA scan and 4 (21.1%) patients had an abnormality only in Ga-67 scan. Of 7 patients who had an abnormality on both scan, 5 patients had. an abnormality at same region in both scan and 2 patients had an abnormality at the different sites on the kidneys. With the above results, we speculate that Ga-67 scan and Tc-99m DMSA scan play a complementary role in the patients with upper urinary tract infection.
구강악안면외과에서 의식하진정에 필요한 Midazolam용량에 관한 연구
장재현,김성민,김소희,박영욱 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.3
Conscious sedation is a minimally depressed level of consciousness that retains the patients' ability to maintain the airway continuously and to respond appropriately to physical stimulation and verbal command at any time, produced by a pharmacologic or nonpharmacologic method or a combination thereof. In dental anesthesia, a state of sedation in which the conscious patient is rendered free of fear, apprehension and anxiety through the use of pharmacologic agents. Midazolam is a useful drug of benzodiazepine on minor operation of dentistry. The purpose of this study is to estimate the appropriate dosage protocol of Midazolam to the patient receiving intravenous sedation at the department of oral and maxillofacial surgery. Total subject was fifty-one patients and fifteen patients of this subject were decided to control group that they were not received intravenous sedation. The experimental group was randomly subdivided into two groups and each of those groups was administrated to 0.05 ㎎/㎏ and 0.08 ㎎/㎏ each other. All patients of the subject were surveyed with postoperative one day questionaire to evaluate the level of sedation. We found that the result was statistically significant between the experimental and the control, and so we present the protocol of the department of oral and maxillofacial surgery, Kangnung National University Dental Hospital.
1주일의 격일 반신수욕이 활동한선밀도 동원력에 미치는 영향
이정범(Jeong-Beom Lee),김태욱(Tae-Wook Kim),양훈모(Hun-Mo Yang),민영기(Young-Ki Min),김소영(So-Young Kim),서형석(Hyung-Seok Seo),이재림(Jae-Rim Lee) 한국생활환경학회 2013 한국생활환경학회지 Vol.20 No.2
The aim of this study is to confirm whether the experienced in short-term and intermittent half body bath (4 sessions, lower body immersion, 42±0.5℃, 30 min/session, for 7 days) can have an influence on the change of the recruitment of activated sweat gland density (ASGD). Subjects were 10 male university students (23.17±2.58 years old, 173.16±3.28 cm height, and weighing 67.68±5.23 kg) who live in Cheonan, Chungnam having no experienced in an artificial thermal stress. This study obtained the mean ASGD from torso (chest, upper back, lower back, abdomen) and limb (upper arm, forearm, thigh, leg) before and after short-term and intermittent half body bath. As the result, it was found that the experienced in short-term and intermittent half body bath significantly increased the whole body sweat loss volume and mean ASGD (p < 0.001). And ASGD increased rate higher in limb (23.8%) than torso (16.5%). In conclusion, our data support the short-term and intermittent half body bath can have an influence on the recruitment of activated sweat gland density. Therefore, evaporative cooling is further facilitated, thermoregulatory efficiency increased by ASGD.
Blepharoptosis in Behçet’s Disease
So-Min Hwang,On Lim,Min-Kyu Hwang,Min-Wook Kim,Jong-Seo Lee 대한미용성형외과학회 2016 Archives of Aesthetic Plastic Surgery Vol.22 No.3
Behçet’s disease is a systemic chronic disease that occurs in tissues such as eyes, joints, organs and nerves, and it has been noted that symptoms may be observed in a variety of tissues. In previous studies, reports of blepharoptosis observed in patients with Behçet’s disease have been rare. We would like to report a case where a patient among those who visited our hospital with blepharoptosis had a history of Behçet’s disease. This patient had been diagnosed with Behçet’s disease, and complained of bilateral blepharoptosis even at the time of diagnosis. He complained of dysfunctions in vision and hearing, and upon eye examination, an eye movement disorder was found in his left eye. From the symptoms, neuro-Behçet’s disease was diagnosed. The oculomotor and levator palpebrae superioris muscles are both controlled by cranial nerve III, which may suggest that Behçet’s disease in this patient occurred in cranial nerve III. The patient received an oral steroid, and the symptoms have improved without surgery. Since we could identify the correlation between Behçet’s disease and blepharoptosis, we considered that sharing this case and its outcome would be helpful for plastic surgeons who treat eyelids.
Acute Pancreatitis as a Complication of Adult Henoch-Schonlein Purpura
( Min Wook So ),( You Jae Kim ),( Hwan Sung Park ),( Yong Gil Kim ),( Chang Keun Lee ),( Bin Yoo ) 대한류마티스학회 2012 대한류마티스학회지 Vol.19 No.1
Pancreatitis is a rare manifestation of adult Henoch- Schonlein purpura (HSP). We describe here a 53-year-old man who presented with acute pancreatitis as a complication of adult HSP. Pancreatic involvement in HSP is self-limiting and benign. Prompt resolution can be achieved by treatment with steroids. Elevated serum amylase and lipase concentrations may be early diagnostic indicators of HSP pancreatitis. Patients with HSP who have abdominal pain should be evaluated for pancreatitis by measuring serum amylase and lipase concentrations and by abdominal computed tomography scan, to plan specific treatment and avoid unnecessary surgery.
( Min Wook So ),( Sang-hyon Kim ),( Dong Wook Kim ),( Yoon-kyoung Sung ),( Jung-yoon Choe ),( Sang-il Lee ),( Jin-wuk Hur ),( Hye-soon Lee ),( Sang-heon Lee ),( Jin Ran Kim ) 대한류마티스학회 2024 대한류마티스학회지 Vol.31 No.2
Objective: The objective of this prospective, observational multicenter study (NCT03264703) was to compare the effectiveness of single conventional disease-modifying anti-rheumatic drug (cDMARD) plus anti-tumor necrosis factor (TNF) therapy versus multiple cDMARD treatments in patients with moderate-to-severe rheumatoid arthritis (RA) following cDMARD failure in the real-world setting in South Korea. Methods: At the treating physicians’ discretion, patients received single cDMARD plus anti-TNF therapy or multiple cDMARDs. Changes from baseline in disease activity score 28-joint count with erythrocyte sedimentation rate (DAS28-ESR), corticosteroid use, and Korean Health Assessment Questionnaire (KHAQ-20) scores were evaluated at 3, 6, and 12 months. Results: Of 207 enrollees, the final analysis included 45 of 73 cDMARD plus anti-TNF and 91 of 134 multiple-cDMARD recipients. There were no significant between-group differences (BGDs) in ANCOVA-adjusted changes from baseline in DAS28-ESR at 3, 6 (primary endpoint), and 12 months (BGDs -0.18, -0.38, and -0.03, respectively). More cDMARD plus anti-TNF than multiple-cDMARD recipients achieved a >50% reduction from baseline in corticosteroid dosage at 12 months (35.7% vs 14.6%; p=0.007). Changes from baseline in KHAQ-20 scores at 3, 6, and 12 months were significantly better with cDMARD plus anti-TNF therapy than with multiple cDMARDs (BGD -0.18, -0.19, and -0.19 points, respectively; all p≤ 0.024). Conclusion: In the real-world setting, relative to multiple cDMARDs, single cDMARD plus anti-TNF therapy significantly improved quality-of-life scores and reduced corticosteroid use, with no significant BGD in disease activity, in RA patients in whom previous cDMARD therapy had failed.
스마트 헬스케어 기반의 디바이스 접근제어를 위한 키 생성 및 통신기법 설계
민소연(So-Yeon Min),이광형(Kwang-Hyong Lee),진병욱(Byung-Wook Jin) 한국산학기술학회 2016 한국산학기술학회논문지 Vol.17 No.11
ICT기반의 융합산업인 스마트 헬스케어 시스템은 건강관리부터 원격진료 범위에 걸쳐 다양한 산업분야의 핵심 연구 주제이다. 스마트 헬스케어 환경은 웨어러블 디바이스를 통하여 사용자의 심박 수, 체온, 건강상태 등과 같은 생체정보를 주치의가 있는 병원 네트워크로 전달하는 기술을 의미하며 환자의 다양한 데이터를 수집하고 복합적인 정보를 추론할 수 있는 기술은 스마트 헬스케어 기술의 핵심기술이라 할 수 있다. 그러나 환자에 대한 개인의 의료정보를 다루는 만큼 정보관리에 대한 보안위협이 있으며, 무선 네트워크 환경에서 발생하는 공격기법에 대해서 취약점이 발생할 수 있다. 그러므로 본 논문에서는 스마트 헬스케어 기반의 디바이스 접근제어를 위한 키를 생성 후 생성한 키를 활용하여 안전한 통신 프로토콜을 설계하여 스마트 헬스케어 시스템의 보안성을 강화하였다. 성능평가에서는 스마트 헬스케어 환경에서 발생하는 공격기법에 대해서 안전성 분석을 하고, 기존의 키 암호화 방식과의 보안성 및 효율성을 분석하여 기존의 암호화 방식 대비 대략 15% 향상된 수치를 확인할 수 있었다. Smart healthcare systems, a convergent industry based on information and communications technologies (ICT), has emerged from personal health management to remote medical treatment as a distinguished industry. The smart healthcare environment provides technology to deliver vital information, such as pulse rate, body temperature, health status, and so on, from wearable devices to the hospital network where the physician is located. However, since it deals with the patient"s personal medical information, there is a security issue for personal information management, and the system may be vulnerable to cyber-attacks in wireless networks. Therefore, this study focuses on a key-development and device-management system to generate keys in the smart environment to safely manage devices. The protocol is designed to provide safe communications with the generated key and to manage the devices, as well as the generated key. The security level is analyzed against attack methods that may occur in a healthcare environment, and it was compared with existing key methods and coding capabilities. In the performance evaluation, we analyze the security against attacks occurring in a smart healthcare environment, and the security and efficiency of the existing key encryption method, and we confirmed an improvement of about 15%, compared to the existing cipher systems.
Kim, Min-Wook,Chung, You Chul,Jung, Hee Chan,Park, Moon-Seo,Han, Young-Min,Chung, Yong-An,Maeng, Lee-So,Park, Sang-In,Lim, Jiyeon,Im, Woo-Seok,Chung, Jin Young,Kim, Minky,Mook, Inhee,Kim, Manho The Society 2012 ACUPUNCTURE IN MEDICINE Vol.30 No.3
<P>Electroacupuncture (EA) is a traditional medicine in patients with post-stroke rehabilitation. Brain-derived neurotrophic factor (BDNF) is a potent growth factor involved in recovery following cerebral injury. The aim of the present study was to investigate whether EA increases BDNF levels and facilitates functional recovery.</P>