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Plyometric Training과 비타민 C 투여가 남고생의 체력, 혈중 젖산, 암모니아 및 젖산탈수소효소에 미치는 영향
장준원,김세종,이현미,서혜림,조현숙,고정림,염종우,예정복,백영호 釜山大學校 附設 體育科學硏究所 2003 體育科學硏究所 論文集 Vol.19 No.-
The purpose of this was to examine the effect of plyometric training and vitamin C ingestion on physical fitness and fatigue substance....
Ko, Kwang Il,Park, Kyoung Sook,Lee, Mi Jung,Doh, Fa Mee,Kim, Chan Ho,Koo, Hyang Mo,Oh, Hyung Jung,Park, Jung Tak,Han, Seung Hyeok,Kang, Shin-Wook,Yoo, Tae-Hyun S. Karger AG 2014 American journal of nephrology Vol.40 No.4
<P>Abstract</P><P><B><I>Background:</I></B> The aim of this study was to investigate the association between the dialysate MCP-1 (dMCP-1) and systemic inflammatory and nutritional markers in peritoneal dialysis (PD) patients. In addition, we examined the prognostic value of dMCP-1 on all-cause or cardiovascular mortality in these patients. <B><I>Methods:</I></B> We prospectively followed 169 prevalent PD patients from April 1st 2008 to December 31st 2012. At baseline, dMCP-1 and serum biochemical parameters including high sensitivity CRP (hs-CRP) and albumin were checked. All-cause mortality and cause of death were evaluated during the follow-up period. Based on the median level of dMCP-1, patients were classified as either low or high dMCP-1 groups. <B><I>Results:</I></B> Mean age, hs-CRP, and D/Pcr ratio at 4 h were significantly higher, while serum albumin levels and %lean body mass (LBM) were significantly lower in the high dMCP-1 group. During the mean follow-up period of 47.7 months, all-cause mortality and cardiovascular mortality rate were significantly higher in the high dMCP-1 group (9.6 and 6.3 per 100 person-years, respectively) compared to the low dMCP-1 group (5.1 and 3.1 per 100 person-years, respectively; p = 0.021, 0.038). In multivariate Cox analysis, high dMCP-1 was a significant independent predictor of all-cause mortality (hazard ratio: 1.83, 95% confidence interval: 1.03-3.24, p = 0.039). <B><I>Conclusions:</I></B> dMCP-1 levels are closely correlated with nutritional and systemic inflammatory markers in PD patients. In addition, increased dMCP-1 is significantly associated with higher all-cause and cardiovascular mortality. These findings suggest that local peritoneal inflammation could contribute to poor clinical outcomes in PD patients.</P><P>© 2014 S. Karger AG, Basel</P>
In vitro Derby Imaging of Cancer Biomarkers Using Quantum Dots
Ko, Mee Hyang,Kim, Soonhag,Kang, Won Jun,Lee, Jung Hwan,Kang, Hyungu,Moon, Sung Hwan,Hwang, Do Won,Ko, Hae Young,Lee, Dong Soo WILEY-VCH Verlag 2009 Small Vol.5 No.10
<P>Semiconductor quantum dots (QDs), which have broad absorption with narrow emission spectra, are useful for multiplex imaging. Here, fluorescence derby imaging using dual color QDs conjugated by the AS1411 aptamer (targeting nucleolin) and the arginine–glycine–aspartic acid (targeting the integrin α<SUB>v</SUB>β<SUB>3</SUB>) in cancer cells is reported. Simultaneous fluorescence imaging of cellular distribution of nucleolin and integrin α<SUB>v</SUB>β<SUB>3</SUB> using QDs enables easy monitoring of separate targets in the cancer cells and the normal healthy cells. These results suggest the feasibility of a concurrent visualization of QD-based multiple cancer biomarkers using small molecules such as aptamer or peptide ligands.</P> <B>Graphic Abstract</B> <P>In vitro derby imaging of RGD peptide targeting integrin α<SUB>v</SUB>β<SUB>3</SUB> protein (green in image) and AS1411 aptamer targeting nucleolin protein (red) using two different quantum dots (605 and 655 nm) is successfully visualized in HeLa cells, simultaneously. Fluorescent imaging signatures of the overlay (yellow) from the integrin α<SUB>v</SUB>β<SUB>3</SUB> and nucleolin show the co-localization in the cellular membrane. <img src='wiley_img/16136810-2009-5-10-SMLL200801580-content.gif' alt='wiley_img/16136810-2009-5-10-SMLL200801580-content'> </P>
고미정(Ko Mee-jung),곽창재(Kwak Chang-jae),서보람(Seo Boram),최우정(Choi Woojung) 한국방재학회 2018 한국방재학회논문집 Vol.18 No.2
재난에 대응하기 위해 시행되는 대표적인 국가재난대비훈련인 안전한국훈련은 총 448개 기관(2016년 기준)이 참여하는 국내 가장 주요한 훈련이다. 효과적인 재난대응을 위해 훈련의 중요성이 높아지면서 훈련체계와 평가제도 개선 등의 다양한 연구가 계속되어 왔다. 재난대비훈련의 전 과정에서 재난의 유형과 상황에 따라 훈련의 내용과 질이 달라지기 때문에 재난 상황 시나리오는 재난대비훈련에 있어 중요하다. 그러나 이 시나리오의 작성 기준과 방법이 규정화된 것이 없어 재난유형 및 기관에 따라 시나리오의 차이가 발생하게 된다. 또한 법률 상 지정된 위기관리매뉴얼과의 연계성이 시나리오에 반영되지 않고 있는 실정이다. 본 연구는 재난대응역량을 강화하기 위한 재난대비훈련의 시나리오 작성의 중요성과 위기관리매뉴얼을 이용한 재난유형별 발생시나리오와 기관별 대응시나리오의 작성 가이드를 제시하는 것이 목적이다. 나아가 본 연구의 결과는 위기관리매뉴얼의 간소화에 활용될 것으로 기대된다. Safety Korea Training of representative national disaster response training implemented to respond to disasters is the domestic most important training in which a total of 448 institutions (2016) participate. The importance of training for effective disaster response has increased, and various studies such as improvement of training system and evaluation system have been continued. The disaster situation scenario is important in disaster response training because the content and quality of training varies depending on the disaster type and situation during the entire process of disaster response training. However, there will be a difference between the types of disasters and the scenarios created by the agency that have not prescribed criteria and methods for creating scenarios of disaster situations. In addition, cooperation with the crisis management manual designated by law is not reflected in this scenario in reality. The purpose of this study is to provide a guide for the preparation of scenarios for disaster preparedness scenarios and crisis scenarios using the crisis management manual. The results of this study are expected to be used to simplify the crisis management manual.
고미정(Mee-Jung, Ko),곽창재(Chang-Jae, Kwak),최우정(Woo-Jung, Choi) 한국방재안전학회 2016 한국방재안전학회 학술대회 논문집 Vol.2016 No.-
재난에 대응하기 위해 시행되는 국가단위 훈련의 대표라 할 수 있는 안전한국훈련은 재난상황 에서의 기관별 협업의 효과성과 대응업무의 효율성 확보를 위해 재난유형별 대응기관들이 함께 모여 실제 재난상황처럼 재난대비훈련을 수행하는 것이다. 안전한국훈련 뿐만 아니라 부처별 자체훈련 등 다양한 재난대비 훈련을 수행하고 있는 현재, 모든 훈련의 시작은 재난상황시나리오부터 시작이 된다. 재난 유형별 재난의 발생과 그 진행에 대한 시나리오에 따라 훈련을 수행하는 기관과 대응업무가 구분되기 때문에 시나리오는 재난대비훈련에 있어 중요하다. 그러나 이 시나리오의 작성 기준과 방법이 규정화된 것이 없다보니 재난유형별, 부처별 시나리오에서 차이가 발생하게 된다. 또한 법률 상 지정된 위기관리 매뉴얼과의 연계성 또한 시나리오상에 반영되지 않고 있는 실정이다. 본 연구는 재난대응역량을 강화하기 위한 재난대비훈련의 시나리오 작성의 중요성과 위기관리매뉴얼을 이용한 재난유형별 발생시나리오와 기관별 대응시나리오의 작성 가이드를 제시하는 것이 목적이다. 나아가 본 연구의 결과는 위기관리매뉴얼의 간소화에 활용될 것으로 기대된다.
Subscalarity of (p,k)-quasihyponormal operators
Jung, Sungeun,Ko, Eungil,Lee, Mee-Jung Elsevier 2011 Journal of mathematical analysis and applications Vol.380 No.1
<P><B>Abstract</B></P><P>In this paper, we show that every (p,k)-quasihyponormal operator has a scalar extension and give some spectral properties of the scalar extensions of (p,k)-quasihyponormal operators. As a corollary, we get that such an operator with rich spectrum has a nontrivial invariant subspace. Finally, we prove that the sum of a <I>p</I>-hyponormal operator and an algebraic operator which are commuting is subscalar.</P>
Ko, Young-Tak,Lee, Sa-Ro,Kim, Jong-Uk,Kim, Ki-Hyune,Jung, Mee-Sook The Korean Society of Oceanography 2006 Ocean science journal Vol.41 No.3
The aims of this study are 1) to construct a database using geostatistics and Geographic Information System (GIS), and 2) to derive the spatial relationships between manganese nodule abundance and other geological factors such as metal grade, slope, water depth, topography, and acoustic characteristics of the sub-bottom. Using GIS, it is possible to analyze a large amount of data efficiently, and to maximize the practical application, to increase specialization, and to enhance the accuracy of the analyses. The greater the copper and nickel grade, the higher the rating. The distribution pattern of nickel grade is similar to that of copper grade. The slopes are generally less than $3^{\circ}$ except for seamounts and cliff areas. The rating shows no correlation with slope. The rating is highest for slopes between 2.5 and $3.5^{\circ}$ in block N1 and between 4.0 and $4.5^{\circ}$ in block N3. The topography is classified into five groups: seamount, hill crest, hill slant, hill base or plain, and seafloor basin or valley. The rating proves lowest for seamount and hill crest. Our results show that the rating increases with the water depth in the study area. Nodule abundance dose not show any significant relationship with the thickness of the upper transparent layer in the study area.