Columella 缺損例의 成形外科的 治療 : 1例報告

임풍,조문제,빈주원,함기선 大韓成形外科學會 1976 Archives of Plastic Surgery Vol.3 No.1

Columella defect is a noticable deformity which is seen following its loss secondary to injures, diseases, or surgical excisions. The reconstruction of the defect can be achieved by one of the following four methods as advocated by Converse in 1964, i.e. 1) the cervical tubes, 2) the forehead flaps, 3) the nasolabial flaps, and 4) the composite grafts. There is tendency for most surgeons to prefer the nasolabial flap method because of the lesser extend of resulting scar and deformities. Authors obtained a good result in correcting a columella defect from a chronic inflammatory disease in 27 years old woman. Vomerian and nasal tip flaps were employed to make a new columella and the resulting inner raw surface was covered with buccal mucous membrane of the upper lip. The pedicle of the mucosal flap was detached on 10th postoperative day.

건물 외피의 종류와 특성에 따른 부하 요인의 우선 순위 결정에 관한 연구

임정명,정원주 釜山大學校生産技術硏究所 1999 生産技術硏究所論文集 Vol.57 No.-

본 연구의 목적은 건물의 외피의 종류와 특성에 따른 부하 요인 중에서 우선 순위를 정하고자 하는 것이다. Visual doe 2.5에 의한 시뮬레이션으로 각 요소의 에너지 소비량을 구하여 그 소비량의 부하요인을 조사하여 각 부하의 우선 순위를 구해 내 건물 외피의 설계시 에너지 절약을 위한 설계의 지침을 얻고자 하는 것이다. The purpose of this study is to analyze and establish the effects of various and characteristic loads of outer envelopes and to estimate the priority order. Simulation by visual doe 2.5 calculate the consumptions of each load and to examine the consumptions of each load factor and estimate the priority order and suggest the design strategy of outer envelope of building.

SA 508c-3강의 고온에서 J-R 및 Tmat의 평가

주원식,임만배 東亞大學校 1998 東亞論叢 Vol.35 No.-

In this study, the J-Resistance Curve and material tearing modulus of SA508-C3 steel, which is one of the used nuclear pressure vessel steel, were measured at room temperature, 200℃ and 300℃ according to load ratio analysis and ASTM E813. ASTM E1152, respectively. It was observed that J-R curve and Tmat value decreased as the temperature level invreased. Applicability of Tj proposed by Paris et al as an instability paramter for ductile material is investigated. The results are the Tj parameter may be used as a crack instability parameter.

국소성 분절성 사구체 경화증의 완전 관해 후 발병한 IgA 신병증 1예

임현민,김현정,박민석,주혜원,최원,김상현,박원도 인제대학교 2006 仁濟醫學 Vol.27 No.-

We report a rare case of primary glomerular disease with IgA nephropathy in a 43-year old man. 7-years ago, he was diagnosed with minimal change nephrotic syndrome. After treatment with steroid for 1-year, azotemia and proteinuria were improved. But, nephrotic range proteinuria was relapsed within 1 week after cessation of steroid. Renal biopsy revealed focal segmental glomerulosclerosis, and achived a complete remission with the use of steroids and cyclophosphamide. Then, he was followed up with normal renal function for 4-years. On admission, the patient showed generalized edema and marked proteinuria. In 3rd renal biopsy, mesangial proliferative glomerulonephritis with diffuse global sclerosis was observed. Electron microscopy showed electron-dense deposit on the mesangium with slight mesangial proliferation, and immunofluoroscence microscopy showed granular deposits of IgA and IgM. These features were consistent with IgA nephropathy, different from results of previous biopsies. The pathogenesis of IgA nephropathy occurred with primary FSGS is not clear, as well as treatment. Now, proteinuria is improving, steroid and cyclophosphamide are probably useful for the disease.

SA508-3재의 하중비 방법을 이용한 CT 시험편의 파괴저항곡선 평가

임만배,주원식,김득진 동아대학교 공과대학부설 생산기술연구소 1998 生産技術硏究所硏究論文集 Vol.3 No.1

The fracture resistance curve is one of most important and design techniques employed in nuclear pressure vessel structures. This study is to evaluate the J-R curve characterisitcs for the SA508C-3 by the unloading compliance method and load ratio analysis. The effect of strain aging for the exponential correlation of the J-R curve in this metal are investigated at room temperature, 200℃ and 300℃. The load ratio analysis method can evaluate the J-R curve by using the simple tension load-displacement curve only without the repeat of the unloading and loading. Therefore, the analysis by the proposed load ratio method has a merit, in comparison with the unloading compliance method, which can measure the crack length without the precision measurement equipment.

라덱스 혼입률에 따른 철근콘크리트의 휨파괴 거동특성

정원경,김동호,이주형,임홍범,윤경구 江原大學校 産業技術硏究所 2002 産業技術硏究 Vol.22 No.A

Reinforced concrete(R/C) is commonly used to structures because they have many merits that compressive strength, economy and so on. However, reinforced concrete has a crack at the tensile section which is due to the relatively lower tensile strength than its compressive strength. Latex modified concrete(LMC) has higher tensile and flexural strength than the ordinary portland cement, due to the interconnections of hydrated cement and aggregates by a film of latex particles. The purpose of this study was to investigate the flexural behavior of reinforced concrete beam with latex modified concrete, having the main experimental variables such as concrete types(ordinary portland cement concrete, latex modified concrete), latex contents(0%, 15%), flexural steel ratios(0.012, 0.0235), and with/without shear reinforcement. The beam of LMC showed considerably higher initial cracking loads and ductility than that of OPC, but, similar to ultimate strength and deflection. This might be attributed to the interlocking of hydrated cement and aggregates by a film of latex particles, water retention due to hydrophobic, and colloidal properties of the latexes resulting in reduced water evaporation. The beam with latex modified concrete could be adopted at field for controlling and reducing the tensile crack due to its higher tensile strength.

간헐적 교정력 적용 후 백서 치주인대에서 UNC-50 유전자의 발현

박미경,박주철,임성훈,김광원 대한치과교정학회 2006 대한치과교정학회지 Vol.36 No.4

기계적 응력은 정상적인 발달과정 동안 조직의 항상성에 있어 중요한 역할을 한다. 기계적 응력은 치아 이동과 저작과 같은 상황을 포함한다. 치아 이동과 저작 중에 치주인대 섬유모세포는 기계적 자극을 감지하고 주위의 세포밖 물질과 생체분자 대사의 변동에 의해 반응을 보인다. 그러나 아직까지 기계적 응력 하에서 치주인대 세포에서 발현된 유전자에 관한 연구는 미비한 실정이다. 최근 기계적 응력이 초파리에 존재하는 UNC-50 유전자에 영향을 줄 수 있다고 보고되었다. 또한 UNC-50은 치은 섬유모세포와 비교해 치주인대 섬유모세포에서만 발현된다고 보고되었다. 본 연구에서는 간헐적 교정력 적용 시에 백서의 치아에서 일어나는 치근 및 치주 조직의 조직학적 변화와, UNC-50의 발현 양상을 면역조직학적 염색으로 조사하여 치주인대에서 기계적 응력과 UNC-50의 관련성을 알아보고자 하였다. Sprague-Dawely계 수컷 백서 12마리를 4마리씩 세 군으로 나누어 상악 우측 구치부에 NiTi closed coil spring을 사용하여 40 g 정도의 견인력이 발생하도록 하여 하루에 1시간씩 간헐적인 교정력을 적용한 후 1, 3, 5일 후 치주인대의 조직학적 변화를 관찰하여 다음과 같은 결과를 얻었다. 조직학적 소견에서 상악 제1대구치 근심구개치근의 치근부 1/3에서 압박측은 안장측보다 더 좁은 치주인대공간을 보였고 교정력을 적용시킨 후 3일 후부터 인장측에서 백악모세포 활성으로 인한 백악질 침착이 관찰되었다. UNC-50은 인장측의 분화 중인 백악모세포에서 강한 발현을 보였다. Osteocalcin은 인장측에서 압박측에 비해 신생 백악질에 존재하는 분화 중인 백악모세포를 따라 강한 발현을 보였다. 이상의 연구결과는 UNC-50이 간헐적 교정력 즉 기계적 응력의 변화에 따른 백악모세포의 분화과정에 중요한 역할을 함을 나타낸다. 그러나 이를 명확히 하기 위해서는 교정력 적용 후 UNC-50의 세포내 신호전달과정에 대한 보완연구가 필요할 것이다. Objective: Periodontal ligament fibroblasts have an ectomesenchymal origin and are thought to play a crucial role for not only homeostasis of periodontal tissues but also bone remodeling, wound healing and regeneration of tissues. Recently, it has been reported that UNC-50 is not expressed in gingival fibroblasts but in PDL fibroblasts. The purpose of this study was to examine the expression of UNC-50 and osteocalcin in the periodontium after application of intermittent force. Methods: Twelve rats had 40 grams of mesially-directed force applied at the upper molar for 1 hour/day. Four rats were sacrificed at 1, 3 and 5 days. Immunohistochemical localization of UNC-50 and osteocalcin antibody was carried out. The results showed apposition of new cellular cementum and a slight increase in periodontal space at the tension side. Results: Strong UNC-50 expression was observed in the differentiating cementoblasts close to PDL fibroblasts in the tension side whereas it was barely expressed at the compression side. Expression was strong at day 3, and decreased at day 5. Osteocalcin immunoreactivity expression was strong in differentiating cementoblasts at the tension side. Conclusion: It can be suggested that UNC-50 is related to the differentiation of cementoblasts, and may be responsible for the molecular event in PDL cells under mechanical stress.

Efficacy of Intracytoplasmic Sperm Injection for Leukocytospermia

강희규,--,--,--,--,--,--,--,-- THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 2004 Journal of biomedical laboratory sciences Vol.10 No.1

White blood cells (WBCs) are present in most human ejaculates, but abnormally high concentration of seminal leukocytes map reflect an underlying pathological condition. The World Health Organization (WHO) has defined leukocytospermia as status of more than 10^(6) WBC/mL of semen. The purpose of this study was firstly, to compare the outcomes between conventional IVF and ICSl in leukocytospermia, and secondly, to investigate whether ICSI may be an alternation treatment for patients with leukocytospermia. Total 346 cycles of conventional IVF and ICSI candidates underwent IVF cycles at Eulji Hospital Infertility Clinic. Semen Parameters including concentration, motility, morphology of spermatozoa and concentration of leukocytes were assessed from the raw ejaculates. There was no difference in sperm concentration, motility and morphology. The rates of fertilization and good embryo development from ICSI were significantly higher than those from conventional IVF in leukocytospermia (60.4% & 32.5% respectively for ICSI group and 44.4% & 28.5%, respectively for IVF group, P<0.001). The pregnancy rate after ICSI was also higher than that from conventional IVF (34.0% vs 29.1%. P<0.05). These results indicate that the presence of seminal leukocyes (>1×10^(6) WBC/mL of semen) is adversely related with fertilization, embryo development and pregnancy rate. Therfore the measurement of seminal leukocytes in routine semen analysis appears to be of prognostic value with regard to male fertilizing potential. In conclusion. it is suggested that ICSI is an alternative choice of treatment for patients with leukocytospermia.

Left Ventricular Thrombus and Subsequent Thromboembolism, Comparison of Treatment Modalities

( Joo Myung Lee ),( Jin Joo Park ),( Hee Won Jung ),( Young Seok Cho ),( Il Young Oh ),( Chang Hwan Yoon ),( Jung Won Suh ),( Eun Ju Chun ),( Sang Il Choi ),( Tae Jin Youn ),( Cheong Lim ),( Goo Yeong 대한내과학회 2012 대한내과학회 추계학술발표논문집 Vol.2012 No.1

Inverse Relationship Between <i>Helicobacter Pylori</i> Infection and Asthma Among Adults Younger than 40 Years : A Cross-Sectional Study

Lim, Joo Hyun,Kim, Nayoung,Lim, Seon Hee,Kwon, Jin-Won,Shin, Cheol Min,Chang, Yoon-Seok,Kim, Joo Sung,Jung, Hyun Chae,Cho, Sang-Heon,Siddiqi., Haseeb Wolters Kluwer Health 2016 Medicine Vol.95 No.8

<P><B>Abstract</B></P><P>Recent studies have suggested that <I>Helicobacter pylori</I> could prevent allergic disease, particularly in children. However, whether this is true in adults is controversial. The aim of this study was to investigate whether there is negative association between <I>H. pylori</I> infection and asthma among adults in an area with a high prevalence of <I>H. pylori</I>.</P><P>This was a cross-sectional study using 2011 health surveillance data. Blood samples were taken from all participants to measure serum <I>H. pylori</I> IgG status. Information on demographics, socioeconomic status, and medical history, including asthma and other allergic conditions were collected by a questionnaire.</P><P>Of the 15,032 patients, 9492 (63.1%) had a history of <I>H. pylori</I> infection, 359 (2.4%) had asthma, and 3277 (21.8%) had other allergic conditions. <I>H. pylori</I> infection was positively correlated with age (OR, 1.050; 95% CI, 1.047–1.053, <I>P</I> < 0.001). Asthma history was positively correlated with age (OR, 1.022; 95% CI, 1.013–1.032, <I>P</I> < 0.001). <I>H. pylori</I> and age were shown to have interaction on asthma in the total participants (OR, 1.041; 95% CI, 1.021–1.062, <I>P</I> < 0.001). In subgroup analysis, <I>H. pylori</I> infection among those < 40 years old was inversely correlated with asthma (OR, 0.503; 95% CI, 0.280–0.904, <I>P</I> = 0.021). Other allergic conditions were not related with <I>H. pylori</I> infection among the total and those <40 years old.</P><P>The inverse association between <I>H. pylori</I> infection and asthma among young adults suggests that the underlying immune mechanism induced by <I>H. pylori</I> infection may affect allergic reactions associated with asthma in young adults.</P>