Factors influencing choosing teaching as a career: South Korean preservice teachers

Jeong‑Ae Lee,Mi Ok Kang,Bitnara Jasmine Park 서울대학교 교육연구소 2019 Asia Pacific Education Review Vol.20 No.3

This study validated the underlying factor structure of the Factors Influencing Teaching (FIT)-Choice survey in the South Korea context and examined motivations and perceptions of 903 Korean preservice teachers by major demographic characteristics. Secondary preservice teachers reported significantly higher values than elementary preservice teachers for Qualification fit and desire to teach and Task return. Male preservice teachers believed more strongly than female preservice teachers that they chose the teaching profession because of Qualification fit, Influencing others, and Task return. Compared to freshmen/sophomores, juniors/seniors reported significantly higher values for Task demand. Participants with low- to medium-level self-reported income ($12K–$46K) weighted Benefits significantly higher than those with medium-level income ($46K–$88K). STEM majors reported higher values for the Qualification fit and Influencing others than non-STEM majors. As South Korea is one of the few countries which has an oversupply of highly qualified teacher candidates, findings were compared with other countries to provide useful insights to improve recruitment of highly qualified individuals to teaching workforce in many countries where teacher shortage is a chronic problem. Based on these data analyses, we argue that policy makers, politicians, education researchers, and others who care about quality education and student academic achievements need to make efforts to increase task returns and benefits.

강천산군립공원 탐방로의 물리적 특성 및 훼손유형

정원옥(Won-Ok Jeong),강원석(Won-Suk Kang),이봉찬(Bong-Chan Lee2) 국립공원연구원 2011 국립공원연구지 Vol.2 No.3

강천산군립공원 5개 탐방로 18.45 km 구간에 대한 물리적 특성과 훼손정도 및 훼손유형 등을 조사한 결과를 요약하면 다음과 같다. 104개 측점을 대상으로 탐방로 물리적 특성을 조사한 결과, 평균 노면경사는 13.34o, 평균 노폭은 1.39 m, 평균 나지폭은 1.20 m, 노면의 평균 최대 침식깊이는 0.50 m로 조사되었고, 훼손정도는『건전』구간이 14.19 km(76.91%),『강』구간은 1.15 km(6.23%),『중』구간은 1.30 km(7.05%),『약』구간은 1.81 km(9.81%)로 전체 구간에 대한 훼손비율은 23.09%였다. 자연 상태의 탐방로 상에서 물리적 훼손의 발생 및 진행과정을 기준으로 훼손 유형을 분석한 결과, 6개의 훼손유형이 217회 발생하였으며 노면침식 현상(36%)이 가장 많았고, 다음으로 뿌리노출(26%), 암석노출(15%), 노폭확대(11%), 비탈붕괴(7%), 수목 및 암석 노출 등 통행불편으로 형성된 분기(5%) 순으로 조사되었다. The purpose of this study was to analyze the trail deterioration condition and to obtain information for the desirable maintenance and restoration of a trail in gangcheonsan county park. The physical characteristics of a trail were surveyed to a total of 104 points of 18.45 km length. The average trail degree and width were found to be 13.34o and 1.39 m respectively while the average bared trail width was 1.20 m and average maxim trail depth was 0.5 m. Deterioration classes of a trail were 14.19 km (76.19%), 1.15 km(6.23%), 1.30 km(7.05%) and 1.81 km(9.81%) for nondeteriorated, heavily deteriorated, middle and lightly deteriorated classes respectively with a deterioration rate of 23.09%. Major deterioration types of trail were trail deepen(36%), root exposed(26%), rock exposed(15%), trail widen(11%), slope erosion(7%) and trail diverged(5%) in order of frequency.

Sarcomatoid Carcinoma Arising from Mature Cystic Teratoma

Ho-Chang Lee1, Seung-Myoung Son, Yong-Moon Lee, Ji Hae Koo, Song-Yi Choi, Ok-Jun Lee, Eun-Hwan Jeong 충북대학교 동물의학연구소 2012 Journal of Biomedical and Translational Research Vol.13 No.2

Malignant transformation of mature cystic teratoma (MCT) is rare. Sarcomatoid carcinoma is a neoplasm comprising malignant mesenchymal cells and a conventional carcinomatous area. Here, we report on a case of sarcomatoid carcinoma arising from an MCT in the left ovary of a 45-year-old female. A unilocular cyst consistent with MCT was observed; however, a nodule within the cyst was confirmed from the resected ovary. Microscopically, the nodule showed both squamous cell carcinoma and pleomorphic sarcomatous components admixing with each other. Lining epithelial cells at the periphery of the main tumor showed squamous metaplasia. When a sarcomatous component is observed in the ovary tumor, it is important to find a squamous cell component, either benign or malignant.

Compound K Inhibits Basic Fibroblast Growth Factor-Induced Angiogenesis <i>via</i> Regulation of p38 Mitogen Activated Protein Kinaseand AKT in Human Umbilical Vein Endothelial Cells

Jeong, Arong,Lee, Hyo-Jung,Jeong, Soo-Jin,Lee, Hyo-Jeong,Lee, Eun-Ok,Bae, Hyunsu,Kim, Sung-Hoon Pharmaceutical Society of Japan 2010 Biological & pharmaceutical bulletin Vol.33 No.6

<P>Compound K (CK; 20-<I>O</I>-β-<SMALL>D</SMALL>-glucopyranosyl-20(<I>S</I>)-protopanaxadiol), an active ginseng saponin metabolite, exerts anticancer activity <I>via</I> apoptosis induction in various cancers. In the present study, we investigated the anti-angiogenic activity of CK and its molecular mechanisms in human umbilical vein endothelial cells (HUVECs). Angiogenesis was induced in HUVECS by basic fibroblast growth factor (bFGF), a potent angiogenic growth factor. CK significantly inhibited the proliferation and also attenuated the expression of a proliferating protein cyclin D1 in bFGF treated HUVECs. Also, CK significantly inhibited the migration and tube formation of bFGF treated HUVECs at non-cytotoxic concentrations, reduced secreted level of vascular endothelial growth factor (VEGF) and increased the secreted level of pigment epithelium-derived factor (PEDF) in HUVECs. In addition, CK effectively disrupted bFGF-induced neo-vascularization in the Matrigel plugs excised from mice <I>in vivo</I>. Notably, we have found that CK downregulated the phosphorylation of p38 mitogen-activated protein kinase (MAPK) and AKT in bFGF treated HUVECs. Taken together, our findings for the first time indicate that CK exerts anti-angiogenic activity <I>via</I> inhibition of p38 MAPK and AKT in HUVECs with the potential of a cancer chemopreventive agent.</P>

Tumor Suppressor Serine/Threonine Kinase LKB1 Expression, Not Kinase Activity, Increased in the Vascular Smooth Muscle Cells and Neointima in the Rat Carotid Artery Injury Model

Jeong, Jin-Ok,Kim, Jeong-Hee,Ahn, Kye-Taek,Park, Hyung Seo,Jang, Won Il,Park, Jae-Hyeong,Lee, Jae-Hwan,Choi, Si Wan,Kim, Jin Man,Seong, In-Whan The Korean Society of Cardiology 2010 Korean Circulation Journal Vol.40 No.11

<P><B>Background and Objectives</B></P><P>Vascular smooth muscle cell (VSMC) proliferation is responsible for the restenosis of previously inserted coronary stents. Angiotensin II (Ang II) is known to regulate VSMC proliferation. LKB1, a serine/threonine kinase, interacts with the p53 pathway and acts as a tumor suppressor.</P><P><B>Materials and Methods</B></P><P>We assessed the association of Ang II and the expression of LKB1 in primary cultured murine VSMCs and neointima of the Sprague Dawley rat carotid artery injury model. We created carotid balloon injuries and harvested the injured carotid arteries 14 days after the procedure.</P><P><B>Results</B></P><P>Ang II increased LKB1 expression in a time-dependent manner and peaked at an Ang II concentration of 10<SUP>-7</SUP> mole/L in VSMCs. In the animal experiment, neointima was markedly increased after balloon injury compared to the control group. Immunohistochemical studies showed that LKB1 expression increased according to neointima thickness. Ang II augmented LKB1 expression after the injury. Western blot analysis of LKB1 with carotid artery lysate revealed the same pattern as LKB1 immunohistochemistry. Increased LKB1 expression started at 5 days after the balloon injury, and peaked at 14 days after the injury. Although LKB1 expression was increased after the injury, LKB1 kinase activity was not increased. Ang II or balloon-injury increased the expression of LKB1 although the LKB1 activity was reduced.</P><P><B>Conclusion</B></P><P>Ang II increased LKB1 expression in VSMCs and neointima. These findings were not kinase dependant.</P>

Bounds for Network Reliability

Jeong, Mi-Ok,Lim, Kyung-Eun,Lee, Eui-Yong 한국데이터정보과학회 2005 한국데이터정보과학회지 Vol.16 No.1

A network consisting of a set of N nodes and a set of links is considered. The nodes are assumed to be perfect and the states of links to be binary and associated to each other. After defining a network structure function, which represents the state of network as a function of the states of links, we obtain some lower and upper bounds on the network reliability by adopting minmax principle and minimal path and cut set arguments. These bounds are given as functions of the reliabilities of links. The bridge network is considered as an example.

Development of an ISSR-Derived SCAR Marker in Korean Ginseng Cultivars (Panax ginseng C. A. Meyer)

Lee, Jei-Wan,Kim, Young-Chang,Jo, Ick-Hyun,Seo, A-Yeon,Lee, Jeong-Hoon,Kim, Ok-Tae,Hyun, Dong-Yun,Cha, Seon-Woo,Bang, Kyong-Hwan,Cho, Joon-Hyeong The Korean Society of Ginseng 2011 Journal of Ginseng Research Vol.35 No.1

Recently, new ginseng cultivars having superior agricultural traits have been developed in Korea. For newly developed plant cultivars, the identification of distinctiveness is very important factors not only in plant cultivar management but also in breeding programs. Thus, eighty-five inter simple sequence repeat (ISSR) primers were applied to detect polymorphisms among six major Korean ginseng cultivars and two foreign ginsengs. A total of 197 polymorphic bands with an average 5.8 polymorphic bands and 2.9 banding patterns per assay unit across six Korean ginseng cultivars and foreign ginsengs from 236 amplified ISSR loci with an average 6.9 loci per assay unit were generated by 34 out of 85 ISSR primers. Three species of Panax ginseng including the Korean ginseng cultivars, P. quinquefolius, and P. notoginseng, could be readily discriminated using most tested primers. UBC-821, UBC-868, and UBC-878 generated polymorphic bands among the six Korean ginseng cultivars, and could distinguish them from foreign ginsengs. Sequence characterized amplified region (SCAR) marker system was introduced in order to increase the reproducibility of the polymorphism. One SCAR marker, PgI821C650, was successfully converted from the randomly amplified polymorphism by UBC-821. It showed the expected dominant polymorphism among ginseng samples. In addition, the specific polymorphism for Sunwon was generated by treating Taq I restriction enzyme to polymerase chain reaction products of PgI821C650. These results will serve as useful DNA markers for identification of Korean ginseng, especially Sunwon cultivar, seed management, and molecular breeding program supplemented with marker-assisted selection.

Linoleic Acid Attenuates the Toxic Dose of Bupivacaine-Mediated Reduction of Vasodilation Evoked by the Activation of Adenosine Triphosphate-Sensitive Potassium Channels

Lee, Soo Hee,Kang, Dawon,Ok, Seong-Ho,Kwon, Seong-Chun,Kim, Hyun-Jin,Kim, Eun-Jin,Hong, Jeong-Min,Kim, Ji-Yoon,Bae, Sung Il,An, Seungmin,Sohn, Ju-Tae MDPI 2018 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.19 No.7

<P>The goal of this study was to investigate the effect of lipid emulsion on a toxic dose of local anesthetic-mediated reduction of vasodilation evoked by the ATP-sensitive potassium (K<SUB>ATP</SUB>) channel agonist levcromakalim. The effect of lipid emulsion (LE) and linoleic acid on the local anesthetic-mediated reduction of vasodilation and membrane hyperpolarization evoked by levcromakalim was assessed in isolated endothelium-denuded vessels (rat aorta and mesenteric artery) and aortic vascular smooth muscle cells. The effect of LE and linoleic acid on K<SUB>ATP</SUB> channel activity in transfected HEK-293 cells was investigated, as was the effect of LE on bupivacaine concentration. The efficacy of LE in attenuating the local anesthetic-mediated reduction of vasodilation evoked by levcromakalim was correlated with the lipid solubility of the local anesthetic. Linoleic acid attenuated the bupivacaine-mediated reduction of vasodilation evoked by levcromakalim. LE decreased the bupivacaine-mediated reduction of membrane hyperpolarization evoked by levcromakalim but did not significantly alter the mepivacaine-mediated reduction. LE and linoleic acid both reversed the bupivacaine-mediated decrease of K<SUB>ATP</SUB> activity and enhanced K<SUB>ATP</SUB> activity. LE decreased the bupivacaine concentration. Linoleic acid may be the major contributor to LE-induced attenuation of bupivacaine-mediated reduction of vasodilation evoked by levcromakalim via the direct activation of K<SUB>ATP</SUB> channels and indirect effects.</P>

Synergistic effect of emodin in combination with ampicillin or oxacillin against methicillin-resistant <i>Staphylococcus aureus</i>

Lee, Young-Seob,Kang, Ok-Hwa,Choi, Jang-Gi,Oh, You-Chang,Keum, Joon-Ho,Kim, Sung-Bae,Jeong, Gil-Saeng,Kim, Youn-Chul,Shin, Dong-Won,Kwon, Dong-Yeul Informa Healthcare 2010 PHARMACEUTICAL BIOLOGY Vol.48 No.11

<P>Methicillin-resistant <I>Staphylococcus aureus</I> (MRSA) is a substantial contributor to morbidity and mortality. In search of a natural products capable of inhibiting this multidrug resistant bacteria, we have investigated the antimicrobial activity of emodin (EM) isolated from <I>Rheum palmatum</I> L. (Polygonaceae) against 17 different strains of the bacterium. New antimicrobial activity was found using the paper disc diffusion method, agar dilution as well as checkerboard method. Against the 17 strains, the disc diffusion test was in the range of 18-30 mm, and the minimum inhibitory concentrations (MICs) of EM were in the range of 1.5-25 μg/mL. From those results we performed the checkerboard test to determine the synergism of EM in combination with ampicillin (AM) or oxacillin (OX) against all strains. The combined activity of EM and two antimicrobial agents (AM, OX) against all strains resulted in a fractional inhibitory concentrations index (FICI) ranging from 0.37-0.5 and from 0.37-0.75, respectively. The effect of EM with AM and OX was found to be synergistic or partially synergistic. We found that EM reduced the MICs of AM and OX. EM and in combination with AM or OX could lead to the development of new combination antibiotics against MRSA infection.</P>

Expressed Sequence Tag Analysis of Olive Flounder (Paralichthys olivaceus): Genes and Expression Profile from the Liver

Lee Jeong-Ho,Kim Young-Ok,Kim Kyung-Kil,Kim Woo-Jin,Park Doo-Won,Park Jung-Youn,Kim Kyu-Won The Korean Society of Fisheries and Aquatic Scienc 2003 Fisheries and Aquatic Sciences Vol.6 No.3

Expressed sequence tag (EST) analysis was conducted using a cDNA library made from the liver mRNA of olive flounder (Paralichthys olivaceus). In the survey of 421 ESTs, 362 showed significant homology to previously described genes while 59 were unidentified or novel. Comparative analysis of the identified ESTs showed that 69 $(19.0\%)$ clones were identified as homologous to the previously reported olive flounder ESTs, and 279 $(77.1\%)$ clones were identified as orthologs of known genes from other organisms. The remaining 14 $(3.9\%)$ clones were identified as orthologs of known sequences with unknown functions. These tagged cDNA clones, identified and unidentified, could provide fundamental baseline data for genomic studies of this species.