Gender-related Differences in Management of Nonvalvular Atrial Fibrillation in an Asian Population

Lee, Jung Myung,Kim, Tae-Hoon,Cha, Myung-Jin,Park, Junbeom,Park, Jin-Kyu,Kang, Ki-Woon,Shim, Jaemin,Uhm, Jae-Sun,Kim, Jun,Park, Hyung Wook,Lee, Young Soo,Choi, Eue-Keun,Kim, Chang-Soo,Joung, Boyoung,K The Korean Society of Cardiology 2018 Korean Circulation Journal Vol.48 No.6

<P><B>Background and Objectives</B></P><P>Gender-related differences in health care utilization for atrial fibrillation (AF) are increasingly recognized. However, large cohort data for examining gender-related differences in AF are lacking in Asian populations.</P><P><B>Methods</B></P><P>The Registry for Comparison Study of Drugs for Symptom Control and Complication Prevention of AF (CODE-AF Registry) is a prospective observational cohort-study that enrolled participants at 10 tertiary hospitals in South Korea. Baseline characteristics retrieved from the CODE-AF Registry were analyzed.</P><P><B>Results</B></P><P>A total of 6,274 patients were recruited (mean age 67±11 years, mean CHA<SUB>2</SUB>DS<SUB>2</SUB>-VASc score 2.7±1.7, 63% male, 65% paroxysmal AF) from June 2016 to April 2017. Women underwent less electric cardioversion (12.3% vs. 19.6%, p<0.001), less radiofrequency ablation (12.4% vs. 17.9%, p<0.001), and less antiarrhythmic drug therapy (44.7% vs. 49.5%, p<0.001), despite having more severe symptoms (symptom class III or IV, 45.8% vs. 37.5%, p<0.001). Among patients with a CHA<SUB>2</SUB>DS<SUB>2</SUB>-VA score of 2 or more, a slightly higher proportion of women were taking oral anticoagulants than men (85.7% vs. 81.9%, p=0.002), and non-vitamin K antagonist oral anticoagulant (NOAC) use was more prevalent in women than men (70.4% vs. 62.3%, p<0.001). Insufficient NOAC dosing was very common, more so in women than men (61.5% vs. 56.3%, p<0.001).</P><P><B>Conclusions</B></P><P>Female patients with AF were treated more conservatively and rhythm control strategies were used less frequently than in males, even though the female patients with AF had more severe symptoms. While insufficient NOAC dosing was common in both sex, it was significantly more frequent in women.</P>

사업장(事業場) 근로자(勤勞者)의 사상체질(四象體質)에 따른 생활습관(生活習慣), 자각증상(自覺症狀), 건강인식(健康認識)에 관(關)한 연구(硏究)

서명효,강홍구,장두섭,왕명자,차남현,김삼태,권소희,정해경,송용선,이기남,Seo Muoung-Hoy,Kang Hong-Goo,Jahng Doo-Sub,Wang Myoung-Ja,Cha Nam-Hyun,Kim Sam-Tae,Kwon So-Hee,Jung Hae-Kyoung,Song Yung-Sun,Lee Ki-Nam 대한예방한의학회 2003 대한예방한의학회지 Vol.7 No.2

The study was conducted to evaluate the difference of life style, subjective symptoms and health cognition depending on the Sasang Constitution in the industrial workers. The results were as follows ; Constitutional distribution among exposed group were Tae-eum In(38.4%), So-eum In(35.2%), and So-yang In(26.4%) and it was turned out that Tae-eum In took a higher portion of Sasang constitution than other constitutions in technician workers. 'Exercise' and 'Obesity' were found most in Tae-eum In, In So-eum In there were many 'Normal' weight and 'Having digestive disorders' were found most in So-eum In. There were no significant difference in the health cognition among the constitutions. The closer to 'normal' weight, the higher prevalence in 'having' concern about health condition and the more 'normal' condition in sleeping, the higher prevalence of 'having' self-confident in present health.

Orthopantomography에 依한 過剩齒와 先天性 缺捐齒의 發生頻度에 關한 考察

車文豪,金泰鎭,禹元燮 大韓小兒齒科學會 1975 大韓小兒齒科學會誌 Vol.2 No.1

We observed the orthopantomography taken by 800 children who came to our pedodontic department, School of Dntistry, S.N.U. and also got the incidence of supernumerary and congenital missing teeth as follows. ① The children who had supernumerary or congenital missing teeth were 9.75% of all. ② In incidence of supernumerary teeth, male was 0.50% higher than female ③ Incidence of conginital missing teeth was 7.0% and male was 1.0% higher than female. ④ Incidence of congeintal missing teeth was mainly arised from mandible.

양수 다발성 수지 재접합수의 치험례 : 4 cases report

차진한,박명철,김우경,한근태,김수신,백세민 大韓成形外科學會 1990 Archives of Plastic Surgery Vol.17 No.2

Since the first successful replantation operation, several reports have been recorded replantated finger survival with high success rates. But ten and nine digits amputations are not common. It is even more unusual to have all digits suitable for replantation. 4 cases are presented where replantation of ten and nine digits were done at the department of PRS. Guro Hospital, Korea University from March 1987 to Jun 1988. In these cases, the patients were young and healthy, all of ten and nine digits were sharply amputed near the proximal phalanx, so a replantation team of 8 surgeons in alternating fashion replanted all ten and nine digits over 30 hours and each patient received 28 pints of whole blood during the procedure. Under general anesthesia, replantatin of both started simultaneously. All digits survived completely except partial necosis of right little finger in case 1. The ischemic time of each digit ranged from 4 hours and 45 minutes to 31 hours as shown in table 5. The long ischemic time did not criticaly affected the survival of amputated digit. Follow-up was from 12 months to 20 months postoperatively. The functional evaluation revealed as follows: 1. The grasping power ranged 13 lb to 65 lb(average;39.7lb) 2. The pinching power with index finger ranged 5 lb to 15 lb(average:10.2 lb) 3. The palm to pulp distance ranged 0 cm to 6 cm.(average;2.2cm) 4. The two point discrimination ranged 2.5mm to 22mm.(average;7.8mm) 5. The shape of digits were acceptable aesthetically. 6. All 4 patients were able to use both hands well in all activities of daily living.

산국 (Chrysanthemum boreale) 휘발성 추출액 및 EDTA가 미생물 및 인체 치은 섬유아세포에 미치는 영향

차정단,김태영,우원홍,전병훈,김해경,유용욱,김강주,길봉섭 원광대학교 생체재료·매식연구소 2000 원광생체재료·매식 Vol.9 No.1

Chrysanthemum boreale (C. boreale) has been used for the treatment of furuncles, carbuncles, sores, conjunctivitis, headache, vertigo and swollen throats as a folk medicine in Korea, but there is little report about experiment evidence of antimicrobial activity. To investigate the antifungal and antibacterial activity of Chrysanthemum boreale(C. boreale) volatile substance and EDTA, the growth inhibition against Aspergillus nidulans (A. nidulans), Fusarium oxysporum (F. oxysporum), Alternaria mali(Al. mali), Candida albicans (C. albicans), staphylococcus aureus (S. aureus), Streptococcus pyogenes(S. pyogenes), streptococcus mutans (S. mutans), Escherichia coli(E. coli), Helicobacter pylori (H. pylori) and Porphyromonas gingivalis (P. gingivalis) was monitored by agar dilution and broth microdilution method. The antifungal effect of C. boreale on A. nidulans, F. oxysporum, Al. mali and C. albicans was shown at the concentration of 0.04%. The antibaterial effect of C. boreale on S. aureus, S. pyogenes, S. mutans and H. pylori was shown at the concentration of 0.04%. However, the growth was inhibited at the concentration of 0.04% irrespective of the presence of EDTA 0.125% was much higher than higher than that of several concentration of volatile substance. The minimum inhibitory concentrations of volatile substance were 0.16% against S. aureus, 0.04% against S. pyogenes, 0.02% against S. mutans, 0.40% against E. coli, and 0.18% against C. albicans. The growth of human gingival fibroblasts was not affected by C. boreale volatile substances at the concentration of 0.04%. These results indicate that volatile substance from C. boreale may have biologically toxic activities to the microorganisms.

강우렁이 (Sinotia quadrata)의 營養學的 硏究 : 아미노산, 지방산, 무기물의 조성에 관하여 On the Composition of Amino Acids, Fatty Acids & Minerals

車連水,李泰圭,梁熙天 又石大學校 1984 論文集 Vol.6 No.-

This experiment was attempted to studies on nutrition value of pond snail. The results are summarized as follows. 1. The proximate composition of pond snail was shown to be crude protein 60,84%, Crude vat 7.89%, CRUDE ASH 14,26% and total sugar 17.89%, respectively. 2. Glu. Asp. Leu. and Phe. were dominant amino acid in pond snail, having 16.77%, 8.6%, 7.99% and 7.19% of total free amino and content respectively. The content of essential amino acid were Ileu. 217.9mg, Leu467.3 mg, Lys. 393.4 mg, Phe. 421.1 mg, Thr. 269.0 mg and Val. 251.1 mg, respectively. 3. The predominant fatty acids were Stearic 30.97%, Palmitic 28.49%, Linolenic 15% and Linaleic 8.12%, Respectively and the P/S Ratio was 0.54. 4. The content of minerals in pond snail were K 1050 mg, Na 106 mg, Ca 1202 mg, Mg 43.3 mg, Cu 10.5 mg, Fe 8 mg and Zn 0.9 mg, respectively.

일부지역 근로자의 스트레스 실태 분석

차성웅,이태영 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.20 No.1

The purpose of this study was to survey the placed worker stress. The subjects in this were 92 people from a place work constituted by residents in U city. After a survey was method by questionnaire. Then, data statistic was conducted by arithmetic mean, frequency analysis were implemented. The conclusions of this study were obtained as follows : Fist, in reason of stress within and outside work places was shown in rank according to embarsssed finances, fellow officials, personal relation and future of work place. Second, in degree result of personal of stess was appeared in rank according to mental, physical, behavioral of consequence. And in degree result of work place of stess was appeared in rank according to unsatisfaction duty, lower duty performance and duty escape. Third, in process cope of stress was shown in rank according to group actvity, reading and music listening, and sound consideration and mind.

미강유의 지방산조성에 관한 연구

차용준,박태홍 國立昌原大學校 基礎科學硏究所 1993 基礎科學硏究所論文集 Vol.4 No.-

As one of studies of rice bran, fatty acid composition in rice bran oil was experimented for the purpose of developing rice bran based snack. The lipid content of rice bran was 15.71% by wet basis, which were composed of 12.62% of nonploar as a neutral lipid and 3.09% of polarlipid as glycolipid and phospholipid. The ratios of neutral, glicoand phospholipid in total lipid were 80.36: 17.86: 1.78%, respectively. Total 21 fatty acids, such as 12 of saturated fatty acids, 4 of mono-unsaturated fatty acids and 5 of poly-unsaturated fatty acids were detected in rice bran lipid. The major fatty acids in total lipid of rice bran were oleic, linoleic and palmitic acids. The fatty acid composition of neutral lipid was similar to that of total lipid. The content of palmitic acid were 21.66% in glycolipid and 33.05% in phospholipid, respectively and also was higher than that in neutral lipid.

음성분석에 입각한 자동코드화 방식의 신경외과계 환자관리 시스템

차은종,김영규,이태수,채수일,김동호,이무섭 충복대학교 의과대학 충북대학교 의학연구소 1994 忠北醫大學術誌 Vol.4 No.1

신경외과계 입원환자의 퇴원요약기록을 전산관리하는 시스템을 개발하였다. 주기억장치 4MB와 보조기억장치 120MB HDD를 장착한 PC-386DX시스템을 기반으로 개발하였고 소프트웨어로는 FoxPro V2.0을 사용하였다. 퇴원 요약기록의 관리시 중요한 항목인 진단명은 통상 사용하는 진단명 그 자체를 입력한 후 해당코드를 자동으로 색출해내는 자동코드화 방식을 사용하였다. 그러나 오류 코드가 발생하기 쉬운 패턴분류 방식을 지양하고 입력오류 발생시 입력진단명을 음성분석하여 음원이 동일한 유사코드를 찾는 음성분석 방식을 취하였다. 두개이상의 유사코드중 사용자가 정확한 코드를 선택하도록 하여 오류코드를 방지하였다. 논리연산조건식을 사용한 검색을 실현함으로써 다양하고 융통성있는 검색기능을 보장하였고 편리한 자료관리 방식이 가능하여 비전문가라 할지라도 손쉽고 편리하게 사용할 수 있었다. 신경외과계 입원환자를 대상으로 사용한 결과 그 실용성을 입증할 수 있었다. A discharge summary data management system was developed for neurosurgical patients. The system, written in FoxPro V2.0, ran on a PC-386DX system equipped with 4MB main memory and 120MB HDD. Automated coding was implemented by comparing the input diagnosis onto the description of the possible code list. However, any alphabet pattern classification techniques were prevented, instead sound analysis was performed on each word of the input diagnosis using the internal sound function of FoxPro software. On an input typing error, the diagnosis codes of similar sound characteristics were presented on screen so that the user selects the accurate diagnosis. This eliminated coding error inevitable for any pattern classification techniques. Data search function of the present system was very powerful and flexible, since the system performs the data search based on the user defined logical equation. In addition, the database management was easy for any inexperienced users to apply, minimizing accidental data loss. The system was tested in the neurosurgery ward and evaluated to be practical and useful.

비만증의 원인과 식이 및 운동처방 프로그램에 관한 이론적 고찰

차성웅,남태호,백영호 釜山大學校 附設 體育科學硏究所 1999 體育科學硏究所 論文集 Vol.15 No.-

Studies on physiological cause of obesity, and research on literature about nutrition and excercise prescription programs for the problem solving have led to the following results. 1. The size and number of fat cells increase sharply during childhood, become stable passing the adolescent period and re-increase at the time of adults. In this sense, earlier diagnosis and treatment of overweight children could prevent adult fatness. 2. A conversional mechanism involving glycerol and fat acids, which is catalyzed by increasingly activated fat dissolution generates fatness and relates to the resistance of insulin and development of diabetes. 3. High calory and fat diets and their physical shapes, flavors and tastes could affect the generation of fatness. 4. DIT as lower relative to a given calory and a defective heat generation of BAT could lead to cumulative body fats. 5. Roles of appetite relate to maintaining balance DIT and consumption calory, staying a weight at a certain level. The malfunction of the lower part of thalami, however, results in hyperphagia and ultimately fatness. 6. The biological adjustment of energy consumption for weight maintenance in spite of energy intake is referred to as set-point. This is possible through diet and exercise. VLCD suppresses appetite too forcefully, and it is common to fail to decrease weight and return to initial levels. Instead, WC is applied which repeats weight decrease, restoration, weight decrease and restoration in order. The more the approach repeats, the more difficult reduction in weight is. 7. Therapies for fatness include those of diet, exercise, behavior and drugs. It is more effective to use diet and exercise therapies together. In this regard, solving the fatness problem depends on nutrition and exercise programs as very suitable for the overweighted people. 8. For a diet therapy, calory to be taken is limited 15 to 20 kcal per overweight, and combination percentages of protein, carbohydrate and fat should be respectively 20,45 and 35 percent while for an exercise therapy, aerobic types of exercise such as walking, jogging, cycling and swimming should be used in such way that they are performed 3 to 6 times a week, 15 to 20 minutes or over each time at the intensity of 60 to 80% of the highest heart rate. 9. Since such exercise programs tend not to be practiced continuously, it is required for the programs to be initially prepared with consideration of motivations and interests on the part of the programs' clients.