In Vitro Fertilization and Embryo Cleavage in Canine Oocytes

Hae }ung Kim,Sang Ryeul Lee,Sin Hae Park,Sung Hyun Kim,Bong Soo Kim,Dong Hun Yoo,Sin Hae Park,Mi Jung Shin,Jae Wook Kim,Zae Young Ryoo 한국동물생명공학회(구 한국동물번식학회) 2006 Reproductive & developmental biology Vol.30 No.2

2003년도 해양스포츠 체험활동을 통한 소아건강교실 사례 발표

김현준,이상엽,이가영,곽현,이남수,김혜선,김윤진,김인주,김용기,대한비만학회 부산분과학회 일동 대한비만학회 2003 The Korean journal of obesity Vol.13 No.4

부산에 소재한 3개 초등학교 청소년단체 소속의 초등하교 3학년부터 6학년까지 구성된 172명을 대상으로 청소년단체 지도자, 초등학교교사, 자원봉사자, 의사와 영양사가 1박 2일간의 해양스포츠 체험활동 을 통한 건강교실을 시행하였다. 대상자의 체질량지수, 체지방량을 측정하여 비만정도를 평가하였으며, 칼로리 섭취에 대한 강의를 시행하였고, 설문지 조사를 통해 대상자의 식이 섭취 습관에 대한 조사를 시행하였고, 본 건강교실에 대한 만족도를 측정하였다. 대상자중 남자에서는 40%, 여자에서는 25.69%에서 비만 경향을 보였다. 대상자의 대부분에서 시행된 건강교실에 긍정적 반응을 보였으며, 향후 체계적인 구성과 철저한 사전계획이 병행되어 본 증례 보고와 같은 건강교실을 시행한다면, 비만아동에서 거부감 없이 비만에 대한 교육을 실시할 수 있으며, 정상 체중 아동군에서도 비만에 대한 예방교육을 시행할 수 있는 프로그램이 될 것이다. 172 elementary school students involved this health program. This subjects were learened about obesity that affect health problem, ideal eating habits, calories that contained in the children's favorite foods by doctors and nutritionist. And this stubjects were checked heights, weight, body fat percent. Obesity is 40% in the boys and 25.69% in the girls. Most subjects were satisfactory with this health program. So we will effectively educate obese children without resistance and prevent normal weight children from obesity through structured and well-designed health program that similar to this program.

2003년도 해양스포츠 체험활동을 통한 소아건강교실 사례 발표

김현주,이상엽,이가영,곽현,이남수,김혜선,김윤진,김인주,김용기,대학비만학회 부산분과학회 일동 대한비만학회 2003 The Korean journal of obesity Vol.12 No.4

Assessment of In Vitro Assay System for Thyroid HormoneDisruptors Using Rat Pituitary GH3 Cells

Hee Jin Kim1,Hae Young Park1,Jeonga Kim1,Il Hyun Kang2,Tae Sung Kim2,Soon Young Han2,Tae Seok Kang2,Kui Lea Park2,Hyung Sik Kim1 한국독성학회 2006 Toxicological Research Vol.22 No.4

The development of in vitro assays has been recommended to screening and test-ing the potential endocrine disruptors (EDs). These assay systems focus only on identifying thethe thyroid hormone (TH) disruptors. The aim of this study was to evaluate a test system to detectTH disruptors using rat pituitary tumor GH3 cells. The test system is based on the TH-dependentincrease in growth rate. As expected, L-3,5,3-triiodothyronine (T3) markedly induced a morphologicalchange in GH 3 cells from flattened fibroblastic types to rounded or spindle-shaped types. T3 stimu-lated GH3 cell growth in a dose-dependent manner with the maximum growth-stimulating effect9 M. In addition, T3 increased the release of growth hor-mone and prolactin into the medium of the GH3 cells culture. Using this assay system, the TH-dis-rupting activities of bisphenol A (BPA) and its related compounds were examined. BPA,dimethylbisphenol A (DMBPA), and TCI-EP significantly enhanced the growth of GH3 cells in therange of 1 × 10-5M to 1 × 10-6M concentrations. In conclusion, this in vitro assay system might bestandardization before it can be used as a broad-based screening tool.

The level of urinary aflatoxin M1 in Korean adults

Yong-Dae Kim1, Hyojin Kwon, Sun-In Moon, Sang-Yong Eom, Jung-Duk Park, Byung-Sun Choi, Seok-Joon Sohn, Young-Seoub Hong, Ho Kim, Ho-Jang Kwon, Ji-Ae Lim, Hae-Jung Yoon, Gwang-Jin Kim, Heon Kim 충북대학교 동물의학연구소 2012 Journal of Biomedical and Translational Research Vol.13 No.3

Competitive ELISA methods were used to measure the level of aflatoxin M1 (AFM1) from urine in 1008 Korean adults. Subjects were selected by random sampling in all areas of Korea, except Cheju-do. The recovery rate of AFM1 using this method was 105% (73-124%). The geometric mean of urinary AFM1 in all subjects was 3.43 pg/mL (3.67 ng/g creatinine). The level of AFM1 in males was statistically higher, compared with female subjects. However, the levels of AFM1 did not differ according to age. Subjects in Chungbuk-do showed the highest urinary AFM1 concentration, whereas subjects in Kyeongnam-do showed the lowest concentration. Assuming an excretion rate of 5%, this AFM1 excretion corresponds to approximately 0.1 microgram/day in Korean adults.

부산지역 근로자들에서 Alcohol Use Disorders Identification Test (AUDIT)와 간기능 검사와의 연관성 조사

손진군,송혜란,이광영,김진하,김호찬 大韓産業醫學會 2003 대한직업환경의학회지 Vol.15 No.3

목적: 세계보건기구에서 알코올의존 이전 단계인 위험 및 유해음주를 조기에 선별하기 위해 개발한 AUDIT와 근오자 정기 건강 진단시 간기능 수치를 조사하여 집단검진에서 AUDIT의 유용ㅇ성과 AUDIT점수와 간기능 이상과의 연관성을 확인 하고자 하였다. 방법: 생산직 근로자 440명을 대상으로 AUDIT설문을 시행하고 이들의 간기능 수치를 측정하여 세계보건기구 기준에 따른 정상, 우험음주와 김종성등(1999)의 기준에 따른 정상, 위험, 유해음주 사이의 간기능의 차이를 비교하고 비정상 간기능에 영향을 미치는 요인들을 비교 하였다. 결과: 체질량지수가 정상인 군에서 세계보건기구 기준에 의한 정상, 위험음주의 비정상 간기능에 대한 단순분석시 교차비는 위험음주가 2.81로 통계적으로 유의하게 높았고, 김종성 등(1999)의 기준에 의한 정상, 위험, 유해음주간의 비정상 간기능에 대한 chi-square test for linear trend 분석시 교차비는 위험, 유해음주에서 각각 1.23, 2.14로 통계적으로 유의하게 높았다. 비정상 간기능에 영향을 미치는 요인들을 다중 로지스틱 희귀분석을 구한 교차비는 AUDIT문항 No. 1-3(고위험군- 2.39), 연령(30대-1.95, 40대-2.40, 50대-3.85), 체질량지수(과체중-1.66, 비만-4.53), 세계보건기구 기준(위험음주-2.10), 김종성 등 기준(유해음주-2.20) 모두에서 통계적으로 유의하였다. 결론: AUDIT를 이용한 음주문제의 선별기준은 간기능 장애와 유의한 연관을 보여 향후 집단 검진시 음주로 인한 간기능 장애의 예측검사와 위험 및 유해음주의 선별검사로 AUDIT활용이 가능 할 것으로 생각된다. Objects: The purpose of this study was to investigate the usefulness of the Alcohol Use Disorders Identification Test (AUDIT) and the relationship between AUDIT score and liver function test. Methods: AUDIT questionnaires were distributed to 440 blue-collar workers. We compared liver function test with firstly, normal and hazardous drinking as measured by Kim et al.(1999). We also compared influencing factors on abnormal liver function. Results: By simple analsis in the normal BMI group, abnormal liver function was significantly affected by hazardous drinking (odds ratio 2.81) based on the guideline of WHO. By chisquare test for linear trend in the normal BMI froup, abnormal liver function was significantly affected by hazhrdous drinking (odds ratio 1.23) and harmful drinking (odds ratio 2.14) based on the guideline of Kim et al. By multiple logistic regression analysis, abnormal liver function was significantly affected by AUDIT questionnaires No. 1-3 (odds ratio risk 2.39), age (odds ratio-thirties 1.95, forties 2.40, fifties 3.85), BMI (odds ratio- overweight 1.66, obesity 4.53), guideline by WHO (odds ratio- hazardous drinking 2.10), and guideline by Kim et al (odds ratio-harmful drinking 2.20) Conclusions: We found that the problem of alcohol drinking as meadured by AUDIT was significantly associated with abnormal liver function. Therefore we suggest that AUDIT will be useful for the predictive test of abnormal liver function and screening test of hazardous and harmful drinking.

일측성 질폐쇄 및 동측 신장 무발생을 동반한 중복자궁 2예

윤일영,여소진,김형문,김정식,김태희,이해혁,남계현,이권해,김준모,김민의 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Uterus didelphys with unilateral obstructed hemivagina and ipsilateral renal agenesis usually presents after menarch with progressive abdominal pain during menses secondary to hematocolpos, and indeed a very rare congenital anomaly due to Mullerian duct malformation. An accurate and prompt diagnosis is of importance to permit treatment and to assure the future fertility of the patient. Pelvic ultrasound, physical examination and pelvic MRI established a diagnosis of hematometracolpos secondary to uterus didelphys with unilateral imperforate hemivagina. An incision in the vaginal septum allowed drainage of the hematocolpos, providing relief of the patients symptoms. We report two case of uterus didelphys with obstructed hemivagina with brief review of the literature.

여성암 환자의 영적건강과 우울의 관계

태영숙(Tae Young Sook),김미예(Kim Mi Yea),김혜나(Kim Hea Na),김혜은(Kim Hae Eun),김혜지(Kim Hea Ji),노영정(No Young Jeong) 고신대학교 전인간호과학연구소 2008 전인간호과학학술지 Vol.3 No.-

Purpose: This study was to identify the relationship between depression and spiritual health in patients suffering from women cancers. Methods: The research method was a cross-sectional descriptive study. Data was collected by questionnaires from 106 in woman patients who were diagnosed with women cancer at one university hospitals and one general hospital. The instruments used for this study included, the Depression Scale developed by Zung(1965) and Spirituality Health Inventory developed by Highfieid(1992) and amended by Lee & Kim. The collected data were analyzed using Frequency, Percentage, t-test, ANOVA, Pearson s correlation coefficients. Results: 1) Depression score was middle, Spiritual Health score was middle 2) The Spiritual Health in women cancer patients indicated a significant negative correlation between spiritual health and depression was perceived with over moderate level(r=-.647, p=.000) 3) There were significant difference in spiritual health according to the Monthly income (F=4.30, p= .016), the degree of pain(F= 2.848,p= .041), the degree of fatigue(F= 3.415,p=.020),the frequency of attendance at worship services(F=3.285, p=.014) the effect of religion on personal life(F= 9.413, p=.000). 4) There were significant difference in depression, according to the residence type(F= .748, p=.012), the cancer insurance(t=7.859, p=.006), the degree of pain(F= 2.775,p= .045). Conclusions: It is needed strategies for intervention of improving the spiritual health to reduce depression in women cancer patients. The significant several characteristics of related to depression and spiritual health should consider in sociopsychological nursing intervention of women cancer patients

간내 담관암의 초음파 및 전산화 단층촬영소견 : Ultrasound and CT Findings

김완진,김표년,김일영,홍현숙,이혜경,권귀향,김기정 순천향대학교 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1

Mo¨nckeberg 중막 석회화로 인해 초기자궁내막암이 진행성 자궁내막암으로 판독되었던 1례

김승만,배철성,김동훈,김정란,이현경,윤혜원 동국대학교 경주대학 1997 東國論集 Vol.16 No.1

Mo¨nckeberg 중막 석회화는 크거나 중간크기의 근육성 동맥(large and medium-sized muscular arteries)의 중막(media)에 노화와 관련되어 퇴행성 과정인 윤상석회화가 특징적으로 나타나는 동맥경화증의 일종으로, 근본적으로 폐쇄성 죽상경화증(occlusive atherosclerosis)과는 다른 과정으로 동맥의 관강(lumen)을 막는 경우는 드물어 상대적으로 임상적 의의는 적거나 거의 없다. 저자들은 Mo¨nckeberg 중막 석회화때문에 초음파 및 컴퓨터 단층촬영에 의한 병기결정에 혼란을 초래하였던 초기 자궁내막암 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. The Mo¨nckeberg medial calcification is aging change rather than disease entity. The Mo¨nckeberg medial calcification involve muscular arteries of limb, head, and genital track and cause fibrosis change associated with hyalinization and fine basophilic staining, suggesting early calcification with little or no clinical significance but is demonstrable on roentgenograms as regular and diffuse radiopaque shadow under intima. We experienced one case of mis-staging of early endometrial cancer due to the Mo¨nckeberg medial calcification therefore, we report this case with a brief review of the literature of the Mo¨nckeberg medial calcification.