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      • S-580 : Vitamin D and carotid subclinical atherosclerosis in SLE

        ( Chang Bum Bae ),( Ju Yang Jung ),( Bo Ram Go ),( Hyun Ah Kim ),( Chang Hee Suh ) 대한내과학회 2013 대한내과학회 추계학술대회 Vol.2013 No.1

        Vitamin D and carotid subclinical atherosclerosis in SLE Chang-Bum Bae, Ju-Yang Jung, Bo-ram Go, Hyun-Ah Kim, Chang-Hee Suh Department of Rheumatology, Ajou University School of Medicine, Suwon, Korea Introduction Atherosclerosis develops earlier in systemic lupus erythematosus (SLE) and is the important cause of mortality. It has been suggested that vitamin D deficiency contributed cardiovascular disease and immune dysregulation in SLE. Methods One-hundred two female patients with SLE and 52 normal controls (NC) were recruited. The carotid artery intima-media thickness (cIMT) and plague were assessed by B-mode ultrasound at the carotid artery level. Vitamin 25(OH)D3 levels were checked by immunoradiometric assay using the Bio-Line 25(OH)D3-Ria CT kit (Bio-Line S.A., Belgium). Disease activity markers were checked at the time of enrollment. Results The cIMT of SLE is 0.41±0.08mm, which is higher than NC (0.37±0.11 mm, p=0.012). Also, carotid artery plague index (PI) of SLE is higher than NC (0.68±1.39 vs 0.26±0.87, p=0.026). The cIMT was correlated with age (r=0.442, p<0.001), body mass index (r=0.246, p=0.013), waist-hip ratio (r=0.245, p=0.013), SLE disease activity index (r=0.239, p=0.016), taking aspirin (r=0.244, p=0.013), and the carotid artery PI was correlated with renal involvement (r=0.224, p=0.023) in patients with SLE. Vitamin 25(OH)D3 was not showed correlation with cIMT and carotid artery PI. Also, it was not correlated with disease activity markers. Conclusion In patients with SLE, the risk of cardiovascular disease measured by cIMT and carotid artery plaque was higher than NC, which may be derived from systemic inflammation. However, vitamin D levels were not showed significant correlations with carotid subclinical atherosclerosis. It may be not suitable to assess vitamin D as marker of disease activity or subclinical atherosclerosis.

      • 고양이의 만성 췌장염 치료 증례

        김현아,윤기영,박정호,이왕희,송근호,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2011 動物醫科學硏究誌 Vol.18 No.1

        A 5-year-old Russian blue cat was referred to the Veterinary Medical Teaching Hospital of Chungnam National University with the history of anorexia, lethargy, weight loss(6.5 to 4.8 kg) 2 weeks ago. Abdominal ultrasonography showed the following : increase of echogenicity of liver, irregular shape of gall bladder, hyperechoic region around duodenum. Pancreatitis, cholangitis, hepatic lipidosis was diagnosed by the ultrasonography. Anti- inflammatory therapy, antibiotic therapy was administered. Abdominal ultrasonography is a efficient available diagnostic tool but serum fPL test reveals the highest sensitivity and specifity result for feline pancreatitis. SNAP fPL test is newly released that can check pancreatitis within 10 minutes by same princple of Spec fPL test used in Gastrointestinal Laboratory of Texas A & M Univerrsity.

      • 農山村 零細私有林所有者의 山林施策 事項에 對한 知識水準

        安鉉哲 진주산업대학교 1984 論文集 Vol.22 No.-

        本硏究는 106名 零細山主에 對한 聽取調査 資料에 依하여 우리나라 農山村에 零細私有林所有者들의 山林施策事項에 關한 知識水準을 究明코자 實施하였다. 이를 爲하여 各山主의 知識評點(0∼5點)을 求하고 山林所有規模, 山主職業, 農地所有規模를 獨立變數로 하여 知識水準을 分析하였다. 本硏究 結果를 要約하면 다음과 같다. 1. 山林施策事項에 對한 私有林所有者의 知識水準은 大體로 낮아서 59.4%가 山主가 低知識水準(0∼2點)을 갖고 있었다. 2. 山林所有規模別 高知識水準의 分布는 5.0㏊ 以下의 山主가 32.5%, 5.1∼11.0㏊의 山主가 40.0%, 11.0∼15.0㏊의 山主가 45.5%, 15.1㏊ 以上의 山主가 62.5%이었다. 3. 山林施策事項에 對한 知識水準을 職業別로 볼 때, 高知識水準이 複合農家山主는 36.5%, 非農家山主는 47.4%이었다. 4. 農地所有規模에 따른 高知識水準 分布는 3,000坪以下가 30.6%, 3,001∼6,000坪이 34.9%, 6,001坪以上이 57.1%이었다. The study was attempted to measure the forest owners' Knowledges Concerning recommended forest policy practices in Agricultural and Mountain villages. For the study, the data were Collected by interviewing 106 private forest owners' in July, 1983. The three independent variables such as forest land scale, Owners' occupation and size of owned Agricultural land, and the one dependent variable, i.e. Knowledge score, were adapted. The results of the study are summarized as follows; 1. As a whole, about 59 percent of forest owners' had the low Knowledge­level(score 0­2) 2. The percentage of forest owners who had high Knowledge­level(score 3­5) by the independent variables are shown below. By the scale of forest land ownership hess than 5.0 hectares 32.5 percent 5.1∼10.0 hectares 40.0 percent 11.0∼15.0 hectares 45.5 percent More than 15.1 hectares 62.5 percent By Owners' occupation Mixed farming forest­owner 36.5 percent Nonfarming forest­owner 47.4 percent By the size of agricultural land Less than 1 hectares 30.6 percent 1.1­2.0 hectares 34.9 percent More than 2.1hectares 57.1 percent

      • 개 비장 질환의 미세세침흡입술을 통한 세포병리학 검사 4례

        김현아,윤기영,최호정,정성목,이영원,조성환,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2011 動物醫科學硏究誌 Vol.18 No.1

        To evaluate the accuracy and diagnostic significance of cytopathological diagnosis of canine splenic disorders, cytopathological examination throgh fine-needle aspiration(FNA) referred to Veterinary Medical Teaching Hospital of Chungnam National University were retrospectived. Splenic neoplasm, hemolymphatic neoplasm, hyperplasia, extramedullary hematopoiesis and splenitis were diagnosed canine splenic disorders through cytopathological examination. The patient should be identified what coagulation profile are normal before aspiration, because complication such as hemorrhage could happen. The 4 cases were identified symmetric, asymmetric splenomegaly on abdominal ultrasonography and then were performed ultrasound-guided FNA. The 4 cases were diagnosed hemangiosarcoma(2), hyperplasia(1) and extramedullary hematopoiesis(1) by clinical signs, hematological examination, and cytopathological examination. Cytopathological examination through FNA was cost-effective, no gneral anesthesia, no complication, and non-invasive method of diagnosis for canine splenic disorders.

      • 치료교육의 실태 및 개선방안 연구 : Issues and Future Delivery System

        안수경,김영태,전헌선,정동일,한현민 국립특수교육원 2005 연구보고서 Vol.- No.5

        본 연구는 2005년 3월 특수교육진흥법 개정에 의하여 특수학교 치료교육교사의 확대배치 및 일반학교 특수학급에의 치료교육 담당교원 배치 등 치료교육 분야의 발전이 예상되는 가운데, 개정법률이 실제 교육현장에 보다 실효성있게 적용되기 위하여 우리나라 특수교육 공교육 상에서 이루어지고 있는 치료교육활동의 실태와 요구를 파악하고 보다 적합한 치료교육을 위한 개선방안을 찾고자 한 정책연구이다. 이를 위하여 본 연구에서는 치료교육의 개념, 역사, 외국 사례 등에 관한 문헌을 탐색하였으며, 설문조사를 통하여 치료교육의 실태와 요구를 분석하였고, 이를 바탕으로 한 치료교육의 개선방안을 도출하였다. 본 연구의 설문조사를 위하여 전국의 142개 특수학교와 182개 지역교육청을 대표하는 1,078명의 교사들로 조사단을 구성하여 설문지를 배부하였다. 그 결과 전국의 16개 시·도교육청에 소속된 142개 특수학교 중 140개 특수학교에서 설문응답에 참여하였으며, 182개 모든 지역교육청에 소속된 교사들이 설문응답에 참여하여, 총 1,046부의 설문지가 수합되었음을 밝힌다. 이 조사를 통하여 치료교육 담당인력의 양적 부족, 치료교육의 내용과 형식에 대한 합의 부족으로 인한 교육실제 상의 혼란이 현 특수학교 치료교육의 대표적인 문제로 제기되었으며, 특수아동 요구의 다양성과 치료교육의 효과성을 동시에 충족하기 위한 치료교육 담당교원의 자격제도 및 배치방법의 해결과 치료교육을 실시하기 위한 공간 확보의 문제가 일반학교 특수학급에서의 치료교육을 위한 주된 요구로 제기되었다. 이와 같은 설문조사의 결과를 바탕으로, 다섯 명의 연구진 중 대학에 재직 중인 세 명의 공동연구자들이 서로 다른 각도에서 치료교육의 문제점과 개선방안을 조명하였다. 따라서 세 가지의 큰 학문적 흐름을 가지고 방안이 주창되었으나, 그 방안 속에서 논해진 구체적인 하나하나의 제안들은 각자의 학문적 입장에서만이 아니라 다양한 현실적 상황을 고려하여 심사숙고된 결과임을 밝힌다. 마지막으로 본 연구의 맺는 말에서는, 일단은 특수교육진흥법과 특수학교 교육과정에 근거하여 교육서비스로서 행해지고 있는 치료교육 시스템의 견고한 틀 안에서의 개선을 논하는 것이 최선일 것으로 보고, 세 가지 큰 흐름의 방안들에서 최소한의 공통되는 제안들을 다음과 같이 종합하였다. 우선 첫째, 치료교육 교사 양성에 있어서의 전공 분야 세분화가 필요하다. 둘째, 기존의 치료교육 교사들이 세부 전공 영역의 전문성을 가질 수 있도록 하는 보완적 교육이 행해져야 한다. 셋째, 특수교사로서의 치료교육교사에 의한 치료교육 제공을 교실교육과 순회교육을 기본 원칙으로 하되, 순회가 불가능한 지역이나 일반학교 일반학급, 일반 유치원 내의 특수아동들을 위하여 필요한 경우에는 교육기관 외의 기관에 소속되어 있는 치료사 인력들을 활용할 수 있는 권역별 인력풀 제도를 마련한다. 넷째, 특수교육과 치료교육의 관계 및 내용적 정체성 확립을 위한 근본적인 재조명이 필요하다. The purpose of the present study is to investigate the current practice of the therapeutic education in Korea. The survey data were collected and analyzed from 332 therapeutic educators, 367 special school teachers, and 347 special classroom teachers. Results of the present study were summarized and discussed by three of the researchers based on their academic standpoints. The problems of current therapeutic education analyzed by this study are the lack of therapeutic educators, confused understanding of the contents and methods of therapeutic education, low professionalism of the therapeutic educators, and the lack of space to carry out therapeutic education in general schools, etc. The common suggestions from the three researchers were summarized as follows: first, the courses of universities for training therapeutic teachers have to be more specialized. Second, some kind of training programs for the existing therapeutic teachers are needed to get them more specialized certificates. Third, the community human resource pool including not only therapeutic teachers but also professional therapists should be available. Fourth, the identity of the therapeutic education in special education delivery system needs to be reestablished academically and practically.

      • 사회정보처리모델을 중심으로 한 공격성에 관한 연구

        서현아,지은주 경성대학교 2000 論文集 Vol.21 No.2

        This study is basic investigation which is to examine young children's aggression in relation to social information processing model. So empirical studies were examined in which were described children's aggression in connection with social information processing model. The summary of the empirical studies is as follows: First, young children's understanding of the concept of intentionality was discussed among the empirical studies. In the recent studies, however, young children were capable of distinguishing between intentional and unintentional actions when stimulus materials used were concrete and familiar to them. Second, a social information processing model of children' aggression is a function of five steps of processing: encoding of social cues, interpretation of social cues, response search, response evaluation and decision, and enactment. This study was examined unto second processing which is interpretation of social cues to get the attribution of other's intention. Response search also was examined by predicted response and alternative solutions. Aggressive groups were more likely to attribute a hostile intention, to predict their response as more hostile and aggressive, to generate less alternative solutions, to evaluate the aggressive response as more effective and positive than non-aggressive groups. In conclusion, it is hypothesized for children who are biased or deficient at each step to act deviant and aggressive social behaviors.

      • Shigella flexneri ATCC 29903를 이용한 ERIC-과 REP-PCR 반응 구성성분 농도의 최적화

        서현아,김근성 중앙대학교 유전공학연구소 2001 遺傳工學硏究論集 Vol.13 No.1

        We attempted to optimize the concentrations of PCR components such as MgCl2, Primers, dNTPs and template DNA to produce fingerpriting patterns of the ERIC- and REP-PCR products for Shigella flexneri ATCC 29903, The ERIC-PCR reactions resulted in a total number of 6 to 9 fragments and the REP-PCR reactions a total number of 10 to 14 fragments. These Phenomena can be explained by the hypothesis that more copies of REP sequences are present on bacterial chromosomes than those of ERIC sequences are. ERIC-PCR reactions generated two major bands of 0.7kb and 1.2kb DNA fragments. They also had the number of PCR products and their band intensity increased as the concentrations of the above four PCR components were increased REP-PCR reactions generated multiple PCR Products between 0.6kb and 4.1kb in size including three major bands of 0.6kb, 0.7kb and 2.2kb DNA fragments. Their band intensity was also increased as the concentrations of the above four PCR components were increased. The PCR reaction cocktails containing 2.0mM MgCl2, 2.0μM primers, 200μM dNTPs and 1.0㎕ template DNA, respectively, yielded the maximum number of PCR products. As the above four components were added more than the concentrations mentioned above in PCR reaction cocktails, the number of PCR products was not increased and the overall fingerprinting patterns remained unchanged. Therefore, a PCR reaction cocktail containing 2.0mM MgCl2, 2.0μM primers, 200μM dNTPs and 1.0㎕ template DNA can be suggested to generate the most optimized PCR fingerprinting patterns .

      • 정상유아 및 정신지체유아의 사물놀이행동에 영향을 미치는 변인 연구

        서현아 慶星大學校 1994 論文集 Vol.15 No.1

        The purpose of this study was to determine the effects of the variables which are play material, gender difference affecting object play behavior exhibited by mentally retarded young children, and nonhandicapped young children. In order to achieve such a purpose, the writer surveyed the study was primarily dependent upon literature as a descriptive and analytic approach for its methodology. The conclusions drawn from the study are as follows. These studies on effects of toys imply that materials made available to children may affect the behaviors they engage in while interacting with play objects and with other children. Toy variables that may affect children's play behavior with blocks and dolls appearing to encourage social interaction and art activities appearing to inhibit it. Art materials appear to enhance functional and constructive aspects of play. Although the results are inconsistent with findings from several researches, gender differences have significant effect on toy preference and type of play behavior. In age difference variable, it is clear that increases in developmental age have been positively associated with increases in play sophistication.

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