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      • "이순신" 멀티미디어 정보 시스템 설계 및 구현

        이혜정,박원환,박두순 순천향대학교 부설 산업기술연구소 2000 순천향 산업기술연구소논문집 Vol.6 No.1

        The purpose of this paper is service system development which enables to carry out the mission of preserving worldwide Korean cultural relics, internationally to contact the informations about our country's cultural relics on the Cyber space, to make atmosphere that makes it possible to appreciate them, and to provide information service by performing mutimedia service which is related to Soon-sin Lee using Virual Reality. For that, creating Virtual Reality information and Video Informaion which is related to Soon-sin Lee, especially Gubooksun by using Virtual Reality technique, 3-Degree image manufacture technique, animation manufacture technique, video manufacture and service technique and Internet/Web technique, and then manufacturing and storing them in the digital data type, and carry out Information Service through connecting the system of serving these informations with the Information SuperHighway

      • Chitosan을 이용한 폐수 중 음이온 (F^-,CN^-)의 제거

        이혜순,박윤창 성균관대학교 기초과학연구소 1992 論文集 Vol.43 No.1

        Chitins and chitosan from crabs and shrimps show an EPR singlet at 2328-2880G. They were linewidth 1152-1877.3G and g values 2.229-2.782. Pure chitins and chitosans were used for adsorption of anions(F^-, CN^-). Generally, the degree of anions adsorption varied with the pH values. Adsorption capacity for anions on shrimp shell was more chitosan than chitin. The degree of adsorption was a function of anions removal from wastewater by chitosan and chitin were carried out. 1g chitosan 100∼200mesh was added to a solution containing F^-(300ppm) and to a solution containing CN^-(300ppm). Respectively and the solution were shaken for 10∼15 minutes and filltered. Adsorption of F^- on chitosan required to reach about 50∼70% completion and CN^- to reach about 70∼80%.

      • 유아교육기관의 운영관리 및 유아기 프로그램 평가

        이소은,하진희,류혜선,박영주,주은혜,이종순 충북대학교 교육생활연구소 2001 생활과학연구논총 Vol.4 No.-

        This purposes of this study were to assess the state of current administration and program contents in early childhood institutes. Using APECP(Assessnt Profile for Early Childhood Programs), assesment data were gathered from 27 apprentices in child care centers and 6 apprentices in Kindergarten in Cheongju. Descriptive statistics and Mann-Whitney test were used to analyze data. The result were as follows : (1) The distribution of percentile rate in administration was from 55% to 78%, and the area of Program Development scored the lowest. The assessments for Kindergarten were higher than those of child care center in the areas of Physical Facility, Food Service, and Program Management. (2) As for the program contents, percentile rate was from 62% to 80%, and generally the assessments for Kindergarten were higher than those of child care center. It appears that the certification and assessment system for ealry childhood institutions should be supervised more strongly in order to improve the qulaity of those institutions.

      • 알타리 무 동치미 제조시 젖산균 첨가가 숙성중 품질에 미치는 영향

        이혜정,오순덕 동아시아식생활학회 2002 동아시아식생활학회지 Vol.12 No.1

        This study examined the chemical and sensory characteristics of Altari Dongchimi with inoculation of Leuconostoc citreum IH22. Dongchimi was stored at room temperature for the first day and at 4℃ from 2nd to 28th day. The pII was somewhat lower in Altari Dongchimi when first inoculated with Leuconostoc citreum IH22 than non-treated Dongchimi. As fermentation proceeded, titratable acidity of Altari Dongchimi significantly increased. The patterns of microfloral changes in both the inoculated and the control were similar during fermentation: the total number of bacteria increased at the beginning, but rapidly decreased right after the optimum ripening point. The hardness and fracturability of both Dongchimi's decreased gradually during fermentation. The evaluation of the sensory qualities showed that the sour taste and fresh taste resulted in similar scores in both Dongehimi's but overall acceptability of the control was higher than that of inoculated one with Leuconostoc citreum IH22.

      • 옥수수種子로부터 抗진균성 chitinase의 분리와 특성에 관한 연구

        이인순,문혜연 대구대학교 과학기술연구소 1997 科學技術硏究 Vol.4 No.1

        Plant exhibit an altered pattern of protein synthesis in response to pathgen invasion and abiotic stress. One of these pathogenesis-related protein has been identified as chitinase, which is capable of hydrolysis fungal cell wall of inhibiting growth. This observation has led to the suggestion that the in vivo role of chitinase is to protect plants against fungal invasion. We purified chitinase from Zea mays L. Golden cross Bantam T-51 by CM-cellulose chromatography. The purified chitinase has a molecular weight of approximately 24kD as detected by SDS-PAGE. In order to known in vitro antifungal activity tested F.oxysporium, F.solani and T.viride. The inhibition rate of each was 35.3%, 18.2%, 52.4%. The specific of substrate condition saw high activity to swllen chitin. The essence of enzyme activity conditions were 30℃±2, pH5.0±0.05, and Zn^(++) ion.

      • KCI등재

        한문학 작품의 수행평가 실천 연구 : 고등학교<한문고전>을 중심으로 Laying Stress on High School Classical Chinese Works

        이혜순,최난영 이화여자대학교 사범대학 교과교육연구소 2004 교과교육학연구 Vol.7 No.3

        The purpose of this thesis is to examine whether performance assessment of Chinese literary works is useful and whether the test enhances students' understanding and interest in Chinese literary works. The first chapter presents the reason why performance assessment of Chinese literature is necessary as a means of expanding students' understanding and interest in Chinese literature, study purpose, and study method. The second chapter seizes the nature of performance assessment and examines the situation, direction, and necessity of performance assessment in education of Chinese literary works. In the third chapter, the assignments were given : for 'A Pearl Swallowed by A Goose(an anecdote by Yoonhwe, 尹淮)', 'to write your own experience related with the topic' : for 'Chinese poems, Gyujong(閨情) and Sangsamong(想思夢)', 'to rewrite the two poems in the form of letters' : and for 'Goungseol(鏡說)', 'to rewrite the essay with different viewpoint'. The forth chapter collects a questionnaire in order to seize whether the assignments played a role for the students to understand Chinese literary works and to take an increasing interest in them after the assignment. The results were analyzed in search of any problem for some improvement in performance assessment. The following facts are revealed from the analysis : (1) The plan of performance assessment of Chinese literary works helped the students understand the works. (2) The plan played a stimulating role in arousing their interest in the works. (3) If the plan is supplemented, the plan could become a teaching-learning plan and an evaluation plan. However some problems are revealed from the analysis in spite of the above affirmative effects : There is the tendency that the students are unable to do their assignments in a creative and varied way because they are conscious of their tests. The students are pressed for time to do their assignments and the teacher' office hours are also insufficient, The students do not come close to Chinese literary works but they regard them only as an evaluation. These problems could be solved only after more of teaching-learning method and evaluation plans by which the students come close to the works with earnest interest are formed.

      • 인진호(茵蔯蒿) 성분의 간세포 유리기 생성에 미치는 영향

        이정규,김순신,김혜경 慶星大學校 1998 論文集 Vol.19 No.1

        Artemisiae iwayomogii Herba, the aerial part of Artemisia iwayomogi Kitamura(=A.messer-schimidtiana Besser, Compositae), which is commonly called as 'Injinho' in Korea, is widely used as choleretic, antiinflammatory or diuretic remedy in oriental region. According to the result of preliminary study on antitoxidant activities author tried to confirm the effects on free radicals generation in liver cells. Among eight constituents isolated chlorogenic acid as well as jaceosidin showed prominent inhibitory activity against free radical generation in cultured liver cells. The activities in sequence of strength were chlorogenic acid 〉 jaceosidin 〉 2,4-dihydroxy-6-methoxy acetophenone 4-O-glucoside 〉 scopolin 〉 apigenin 7,4'-dimethyl ether.

      • 마우스 胎仔 小腸의 杯狀細胞 出顯에 關한 硏究

        李惠星,金淳會 梨花女子大學校 韓國生活科學硏究院 1986 韓國生活科學硏究院 論叢 Vol.37 No.-

        소장의 배상세포는 장선에서 발생되고 이들은 융모상피로 이주 한 후에 장내강으로 탈락되는 것으로 알려져 있다. 그런데 이와 같은 사실은 모두 성체(adult)에서 밝혀졌으며 장선과 융모가 형성되기 이전의 태생기에 배상세포의 출현과 분화과정에 대해서는 밝혀진 바 없다. 이에 본 연구에서는 태생기 배상세포의 출현시기와 동태를 파악하기 위하여 마우스 태자 소장을 광학 및 전자현미경으로 관찰하여 다음과 같은 소견을 얻었다. 1. 마우스 태자의 소장에서 보통배상세포와 과립점액세포는 다같이 태령 15일부터 나타났으며, 이때에 대부분의 이들 세포들은 소수의 점액과립을 함유하고 있었다. 2. 태령 16,17일 태자의 배상세포 수는 급격히 증가하며 그 이후 태생말기까지는 비슷한 수준을 유지하였다. 3. 각 태령에서 보통배상세포와 과립점액세포의 출현율은 각각 약 80% 및 20% 정도로서 태령에 따른 차이는 없었다. 4. 태생 말기에 과립점액세포에서는 변형된 분비과립의 수가 증가하였다. 5. 보통배상세포와 과립점액세포는 태생말기에 과립의 분비상태를 나타냈고, 보통배상세포는 융모의 상피에서 장내강으로 탈락되는 경우도 있었다. It is known that the goblet cell in the small intestine of a mouse originated from the crypt base cells of gland and migrated to the upper part of the villus and that it is extruded into lumen of the intestine. But these facts have been observed in the adult small intestine. However, the origin and the process of differentiation of the goblet cell in the fetus prior to the formation of the glands and villi are not known. The present experiment was performed to clarify the developmental stages and the behaviors of the goblet cell in the small intestine of fetal mouse by means of light and electron microscopy. The results obtained could be summarized in five items as follows; 1. Both the ordinary goblet cells and granular mucous cells were identified in the small intestinal epithelia of the 15-day-old fetuses. Most of both these cells contained only a small amount of mucous globules. 2. The number of the goblet cells was markedly increased in the small intestinal epithelia of the 16-and 17-day-old fetuses and it was maintained to the end of the fetal life on the approximately equal level. 3. The frequency of the ordinary goblet cells and granular mucous cells were about 80% and 20%, respectively, regardless of the fetal ages. 4. Toward th end of the fetal life, the number of modified secretory granules of granular mucous cells was increased. 5. Again, toward the end of the fetal life, the ordinary goblet cells and granular mucous cells displayed the secretory states. In addition, the ordinary goblet cells were occasionally extruded into the lumen from the villus tip

      • KCI등재

        정신분열병과 Neurotensin 수용체 유전자 다형성의 연합 연구

        이유상,김형배,한진희,채영규,이정식,이혜순,주연호,김형섭,최인근,양병환 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.6

        연구목적: Neurotensin(NT)은 NT수용체와 결합하여 그 효과를 나타내는 neuromodulator 혹은 neurotransmitter로서 대뇌에서 도파민의 분비를 조절하는데 중요한 역할을 한다. 근래의 연구에 의하면 NT와 그 수용체는 대뇌에서 항정신병 약물의 효과를 매개하는 것으로 생각되고 있으며 약물치료를 받지 않은 정신분열병 환자의 뇌척수액에서 NT의 양이 적으로 보고되고 있어 이들은 정신분열병과 깊은 관련을 가지고 있을 것으로 추정된다. 최근 NT수용체의 유전자의 3`인접영역에서 정보가치가 높은 4 염기반복 다형성이 발견되어 이를 유전 표지자로 하여 정신분열병과의 연합을 알아보았다. 방 법: 서로 혈연관계에 있지 않은 정신분열병 환자 120명(남자 91명, 여자 29명)과 정상 대조군 106명(남자 84명, 여자 22명)을 대상으로 하였다. PANSS를 사용하여 양성 및 음성을 알아보았다. 말초혈액에서 DNA를 분리한 후에 중합효소연쇄반응을 사용하여 3`인접영역에 있는 4 염기 반복 다형성을 증폭하였고 silver staining한 후에 유전자형을 관찰하였다. chi-square 검증과 Bonferroni`s correction을 사용하여 환자군과 정상 대조군간의 대립유전자 빈도의 차이를 알아보았다. 또한 양성 및 음성 환자군으로 나누어 차이를 알아보았다. 결 과: 총 23개의 대립유전자가 관찰되었으며, 399bp의 대립유전자(A10)의 빈도가 환자군보다 정상대조군에서 통계적으로 유의하게 높았다(χ²=16.49, df=1, p<0.001). 음성 정신분열병 환자군과 정상대조군 사이의 비교에서는 정상대조군의 A10의 빈도가 환자군보다 유의하게 높았다(χ²=21.33, df=1, p<0.001). 성별 비교에서 남자 정신분열병 환자군은 대조군에 비하여 A10의 분포가 유의하게 적었다. (χ²=13.71, df=1, p<0.001) 결 론: NT 수용체 유전자와 정신분열병사이에 음성연합이 관찰되었다. NT 수용체 유전자가 일부 정신분열병의 발병과정에서 확실하지는 않지만 어떤 종류의 보호기능을 할 수도 있다는 것을 암시한다. Objectives: Neurotensin(NT), of which functions are evoked by its interaction with neurotensin receptors(NTR), coexists with mesolimbic dopamine and regulates endogenous dopamine release. Recent studies have shown that NT with NTR exerts neuroleptic-like activity within the central nervous system and may play an important role in the pathogenesis and in the treatment of schizophrenia. We have examined the gentic association between schizophrenia and tetranucleotide repeat polymorphism in the 3-flanking region of the NTR gene to investigate the possible contribution of the NTR gene to the schizophrenia susceptibility. Methods: Among 23 alleles identified, the subjects were 120 patients(male 91, female 29)with schizophrenia and 106 normal healthy controls(male 84, female 22). They were unrelated native Korean. PANSS was used to determine positive or negative subgroup in the schizophrenic patients. Using polymerase chain reaction and polyacrylamide gel electrophoresis, tetranucleotide repeat polymorphism(CCTT and CTT) in the 3`-flanking region of NTR gene was observed. For a comparison of NTR gene`s allelic frequencies between patients with schizophrenia and normal healthy controls, chi-square test and Bonferroni`s correction was performed. Results: The frequency of A10 allele(base pair size=399)was significantly higher in normal healthy controls than schizophrenia(χ²=16.4902, df=1, p<.000). In the comparison between schizophrenic patients with negative symptoms and normal controls, the frequency of A10 allele was significantly higher in normal healthy control subjects than patients with schizophrenia(χ²=21.33, df=1, p<0.001). In the case of male, the frequency of A10 allele of schizophrenia was significantly higher than normal controls(χ²=13.71, df=1, p<0.001). Conclusions: NTR gene was negatively associated with schizophrenia. NTR gene`s tetranucleotide repeat polymorphism may provide some protective function against schizophrenia.

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