Efficient Verifiable Top-k Queries in Two-tiered Wireless Sensor Networks

( Hua Dai ),( Geng Yang ),( Haiping Huang ),( Fu Xiao ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.6

Tiered wireless sensor network is a network model of flexibility and robustness, which consists of the traditional resource-limited sensor nodes and the resource-abundant storage nodes. In such architecture, collected data from the sensor nodes are periodically submitted to the nearby storage nodes for archive purpose. When a query is requested, storage nodes also process the query and return qualified data as the result to the base station. The role of the storage nodes leads to an attack prone situation and leaves them more vulnerable in a hostile environment. If any of them is compromised, fake data may be injected into and/or qualified data may be discarded. And the base station would receive incorrect answers incurring malfunction to applications. In this paper, an efficient verifiable top-k query processing scheme called EVTQ is proposed, which is capable of verifying the authentication and completeness of the results. Collected data items with the embedded information of ordering and adjacent relationship through a hashed message authentication coding function, which serves as a validation code, are submitted from the sensor nodes to the storage nodes. Any injected or incomplete data in the returned result from a corresponded storage node is detected by the validation code at the base station. For saving communication cost, two optimized solutions that fuse and compress validation codes are presented. Experiments on communication cost show the proposed method is more efficiency than previous works.

Hath1 Inhibits Proliferation of Colon Cancer Cells Probably Through Up-regulating Expression of Muc2 and p27 and Down-regulating Expression of Cyclin D1

Zhu, Dai-Hua,Niu, Bai-Lin,Du, Hui-Min,Ren, Ke,Sun, Jian-Ming,Gong, Jian-Ping Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12

Previous studies showed that Math1 homologous to human Hath1 can cause mouse goblet cells to differentiate. In this context it is important that the majority of colon cancers have few goblet cells. In the present study, the potential role of Hath1 in colon carcinogenesis was investigated. Sections of paraffin-embedded tissues were used to investigate the goblet cell population of normal colon mucosa, mucosa adjacent colon cancer and colon cancer samples from 48 patients. Hath1 and Muc2 expression in these samples were tested by immunohistochemistry, quantitative real-time reverse transcription -PCR and Western blotting. After the recombinant plasmid, pcDNA3.1(+)-Hath1 had been transfected into HT29 colon cancer cells, three clones were selected randomly to test the levels of Hath1 mRNA, Muc2 mRNA, Hath1, Muc2, cyclin D1 and p27 by quantitative real-time reverse transcription-PCR and Western blotting. Moreover, the proliferative ability of HT29 cells introduced with Hath1 was assessed by means of colony formation assay and xenografting. Expression of Hath1, Muc2, cyclin D1 and p27 in the xenograft tumors was also detected by Western blotting. No goblet cells were to be found in colon cancer and levels of Hath1 mRNA and Hath1, Muc2 mRNA and Muc2 were significantly down-regulated. Hath1 could decrease cyclin D1, increase p27 and Muc2 in HT29 cells and inhibit their proliferation. Hath1 may be an anti-oncogene in colon carcinogenesis.

MiR-150-5p Suppresses Colorectal Cancer Cell Migration and Invasion through Targeting MUC4

Wang, Wei-Hua,Chen, Jie,Zhao, Feng,Zhang, Bu-Rong,Yu, Hong-Sheng,Jin, Hai-Ying,Dai, Jin-Hua Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15

Growing evidence suggests that miR-150-5p has an important role in regulating genesis of various types of cancer. However, the roles and the underlying mechanisms of miR-150-5p in development of colorectal cancer (CRC) remain largely unknown. Transwell chambers were used to analyze effects on cell migration and invasion by miR-150-5p. Quantitative real-time PCR (qRT-PCR), Western blotting and dual-luciferase 3' UTR reporter assay were carried out to identify the target genes of miR-150-5p. In our research, miR-150-5p suppressed CRC cell migration and invasion, and MUC4 was identified as a direct target gene. Its effects were partly blocked by re-expression of MUC4. In conclusiomn, miR-150-5p may suppress CRC metastasis through directly targeting MUC4, highlighting its potential as a novel agent for the treatment of CRC metastasis.

Prognostic Significance of C-reactive Protein in Urological Cancers: a Systematic Review and Meta-analysis

Dai, Jin,Tang, Kun,Xiao, Wei,Yu, Gan,Zeng, Jin,Li, Wei,Zhang, Ya-Qun,Xu, Hua,Chen, Zhi-Qiang,Ye, Zhang-Qun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.8

Background: C-reactive protein (CRP), considered as a prototypical inflammatory cytokine, has been proposed to be involved in tumor progression through inflammation. Recent studies have indicated CRP as a progostic predictor for urological cancers, but the results remain controversial. Materials and Methods: A systematic search of Medline, Scopus and the Cochrane Library was performed to identify eligible studies published between Jan 1, 2001 and Sep 1, 2013. Outcomes of interest were collected from studies comparing overall survival (OS), cancer-specific survival (CSS) and relapse-free survival (RFS) in patients with elevated CRP levels and those having lower levels. Studies were pooled, and combined hazard ratio (HR) of CRP with its 95% confidence interval (CI) for survival were used for the effect size estimate. Results: A total of 43 studies (7,490 patients) were included in this meta-analysis (25 for RCC, 10 for UC, and 8 for PC). Our pooled results showed that elevated serum CRP level was associated with poor OS (HR: 1.26, 95%CI: 1.22-1.30) and RFS (HR: 1.38 95%CI: 1.29-1.47), respectively. For CSS the pooled HR (HR: 1.33, 95%CI: 1.28-1.39) for higher CRP expression could strongly predict poorer survival in urological cancers. Simultaneously, elevated serum CRP was also significantly associated with poor prognosis in the subgroup analysis. Conclusions: Our pooled results demonstrate that a high serum level of CRP as an inflammation biomarker denotes a poor prognosis of patients with urological cancers. Further large prospective studies should be performed to confirm whether CRP, as a biomarker of inflammation, has a prognostic role in urological cancer progression.

A Comparison of Anatomy Education in a Large Chinese Medical School and a Small Korean Medical School

Dai, Jingxing,Ouyang, Jun,Qu, Rongmei,Liao, Hua,Chung, Min Suk,Chung, Beom Sun SciELO Agencia Nacional de Investigación y 2018 International journal of morphology Vol.36 No.2

Nitrogen-doped and hierarchically porous carbon derived from spent coffee ground for efficient adsorption of organic dyes

Dai Zhong,Ren Peng-Gang,Zhang Hua,Gao Xin,Jin Yan-Ling 한국탄소학회 2021 Carbon Letters Vol.31 No.6

Here, a novel nitrogen-doped carbon nano-material (N-CGNM) with hierarchically porous structure was prepared from spent cofee ground for efcient adsorption of organic dyes by a simple one-step carbonization process (the uniform mixture consists of spent cofee ground, urea, and CaCl2 with the ratio of 1:1:1, which was heated to 1000 °C with a rate of 10 °C min−1 and held at 1000 °C for 90 min in N2 atmosphere to carry out carbonization, activation, and N-doping concurrently). The morphology and structure analysis show that the prepared N-CGNM exhibits hierarchical pore structure, high specifc surface area (544 m2 /g), and large numbers of positively charged nitrogen-containing groups. This unique structure and chemical composition endow N-CGNM with an excellent adsorption capacity toward anion Congo red (623.12±21.69 mg/g), which is obviously superior to that (216.47±18.43 mg/g) of untreated spent cofee ground-based carbon nano-materials (CGM). Oppositely, the adsorption capacity of N-CGNM towards cation methylene blue is inferior to that of CGM due to the existence of electrostatic repulsion. These fndings show a great guidance for the development of low-cost but efcient selective adsorbent.

Protective Effects of Scutellaria barbata Against Rat Liver Tumorigenesis

Dai, Zhi-Jun,Wu, Wen-Ying,Kang, Hua-Feng,Ma, Xiao-Bin,Zhang, Shu-Qun,Min, Wei-Li,Lu, Wang-Feng,Lin, Shuai,Wang, Xi-Jing Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1

Scutellaria barbata D. Don (S. barbata), a traditional Chinese medicine, is used to treat cancers, inflammation, and urinary diseases. This study aimed to determine any protective effects of S. barbata crude extract (CE-SB) against rat liver tumorigenesis induced by diethylnitrosamine (DENA). Liver malfunction indices in serum were measured by biochemical examination. Hematoxylin and eosin staining was performed to examine liver pathology. Contents of malondialdehyde (MDA) and superoxide dismutase (SOD) were measured in liver homogenates to evaluate oxidative stress. The levels of liver malfunction indices in the CE-SB groups, especially in the CE-SB high dose group, were lower than that of the model group (P<0.05). The results from histological examination indicated that the number of liver nodules in the CE-SB groups decreased compared with the model group (P<0.05). Content of MDA determined in liver was significantly decreased, and level of SOD elevated by CE-SB. CE-SB can inhibit experimental liver tumorigenesis and relieve hepatic injury in rats.

Research on Natural Gas Leakage Diffusion of Urban Underground Pipeline and its Explosion Hazard

Dai Wang,Peng Liu,Chenguang Hua,Hai Zhang,Chenyang Shi,Jianmei Du 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.2

For the risk of gas leakage and explosion that may occur during the serviceability of urban natural gas pipeline, based on the numerical simulation conducted by FLACS, the gas leakage, explosion and disaster risk under the different speed of wind are mainly studied with local climate characteristics for actual urban street. The results show that the wind speed has an obvious effect on the gas leakage and diffusion, the deviation of gas leakage direction is not obvious for the smaller speed of wind at the initial stage, the horizontal diffusion range gradually increases with the increase of wind speed, while the vertical diffusion range gradually decreases, and the volume of gas at the limit concentration of combustion and explosion gradually decreases. In urban buildings, the overpressure load of higher buildings is lower. After the explosion, the peak overpressure at the same monitoring point decreases with the increase of wind speed. With the increase of distance from the building to the explosion location, the overpressure load on the building decreases and the oscillation effect of overpressure load is relatively gentle. The thermal radiation after burning has great influence on the surrounding buildings and downwind position, especially the buildings around the leakage point.

Neuroprotective Effects of <i>Alpinia Katsumadai</i> Against Neuronal Damage in the Gerbil Hippocampus Induced by Transient Cerebral Ischemia

Li, Hua,Yoo, Ki-Yeon,Lee, Choong Hyun,Choi, Jung Hoon,Hwang, In Koo,Kim, Jong-Dai,Kim, Young-Myeong,Kang, Il-Jun,Won, Moo-Ho Informa Healthcare 2011 International journal of neuroscience Vol.121 No.9

<P><I>Alpinia katsumadai</I>, one of the family Zingiberaceae, contains chalcone, flavonoids, diarylheptanoids, monoterpenes, sesquiterpenoids, stilbenes, and labdanes. It has been reported that the extract of <I>Alpinia katsumadai</I> seed (EAKS) has antiinflammatory effects, and enhances antioxidant activities. We observed the neuroprotective effects of EAKS against ischemic damage in gerbils received oral administrations of EAKS (50 mg/kg) once a day for 7 days before transient cerebral ischemia. In the EAKS-treated ischemia group, neuronal nuclei (NeuN, a marker for neurons)-immunoreactive pyramidal neurons were abundant (68.3%% of the sham group) in the hippocampal CA1 region (CA1) 4 days after ischemia/reperfusion (I/R) compared to those in the vehicle-treated ischemia group (13.18%%). We also observed that EAKS treatment significantly decreased the activation of astrocytes and microglia in the CA1 compared with the vehicle-treated ischemia group 4 days postischemia. In addition, protein levels of GFAP and Iba-1 in the EAKS-treated ischemia group were much lower than those in the vehicle-treated ischemia group 4 days after I/P. Our findings indicate that the repeated supplements of EAKS could protect neurons from an ischemic damage, showing that glial activation is markedly decreased in the ischemic area.</P>

RVA Property analysis of rice varieties under different ecological condition of Yunnan Plateau

Zhen-Hua Zhu,Ki-Young Kim,Bo-Kyeong Kim,Lu-Yuan Dai,Jae-Kwon Ko 한국작물학회 2008 한국작물학회 학술발표대회 논문집 Vol.2008 No.10

Starch RVA profile parameters serve as important indices in the estimation of rice cooking and eating quality. Four cold- tolerant and five cold-sensitive japonica rice varieties grown at 3 different altitudes in Yunnan plateau were used in this experiments. RVA parameters including peak viscosity(PKV), hot viscosity(HTV), final viscosity(FLV), breakdown viscosity(BDV), setback viscosity(SBV) and pasting temperature(PaT) were investigated. SBV and PaT of cold tolerant varieties and PKV, BDV and SBV of cold-sensitive varieties were significantly influenced by environments. The variances of RVA parameters were affected by genotype×environment interactions in cold tolerant and sensitive varieties. The coefficients of variation of RVA parameters except for SBV in cold tolerant varieties were lower than those in cold sensitive varieties. HTV, FLV and SBV of cold tolerant varieties were significantly lower, while PKV, BDV and PaT were significantly higher than those of cold sensitive varieties. With altitude increasing, SBV and PaT of cold sensitive varieties increased significantly, whereas PKV, HTV, FLV and BDV decreased significantly. However, PKV, BDV and PaT of cold tolerant varieties gradually increased while HTV, FLV and SBV increased and then gradually decreased with altitude rising. These results suggested that cooking and eating quality would be improved by improving cold tolerance of rice varieties in breeding program.