뇌손상 환자에게 적용한 흉부물리요법의 비교연구

홍해숙,최영진 대한기초간호자연과학회 2004 Journal of korean biological nursing science Vol.6 No.2

The purpose of this study was to compare chest percussion with chest vibration in brain injury patients. 30 patients in SICU of one general hospital in T city were randomely divided by 3 groups and the arterial oxygen tension(PaO2) and the retained secretion were measured. The chest vibration was done among the first group, the chest vibration by hand after the chest percussion was done among the second group and the mechanical chest vibration after the chest percussion was done among the third group. The data was analyzed using SPSS 7.0 (5% significance) and the results are below. 1) It was adopted the hypothesis that the amount of retained secretion of endotracheal suction after stopping the actions among the first, second and the third groups is different from each other. (F=41.62, p=0.00) 2) It was rejected the hypothesis that the arterial oxygen tension(PaO2)s are different from each other among the first, second and third group. (F=1.22, p=0.31) The amount of the retained secretion after chest percussion, chest vibration by hand or mechanical chest vibration was significantly different from each other. Therefore, chest physiotherapy could be regarded as the effective nursing intervention for the unconscieus patients who have the inappropriate airway cleaness and it was more effective to be together than to be alone.

2000년 부산광역시 서구에서 발생한 세균성이질 역학조사 평가

홍상기,김정규,전진호,손혜숙,이종태 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.3

Purposes : Bacillary Dysentery is one of the representative infectious disease that widely occurred in recent years, Korea. This study was performed to propose the helpful advices for control of Bacillary Dysentery outbreak based on an assessment of the results of epidemiological survey for Bacillary Dysentery outbreak on May 16, 2000 in Busan. Methods : Subjects were 7,188 peoples who showed diarrhea and contacted with active participants in a religious meeting and suspected cases surveyed from May 16 to May 31, 2000. Direct interview about participation, presence of diarrhea, and history of spring water drinking, and rectal swab on the patients who had diarrhea were done. Results : Among 7,188 peoples, 458 patients had simple diarrhea, and 135 patients confirmed infected with Shigella sonnei. Among confirmed cases. 94.8% had actively participated the religious meeting. The first case occurred on May 10, and consecutive outbreak was concentrated on May 12 and 13. Elementary school children(40.7%) and their parents(35.6%), and women(65.2%) were majority of the confirmed cases. Drinking history of the spring water during the meeting was highly suspected as a cause of this outbreak(odds ratio=3.29, 95% confidence interval=1.59∼6.82). Food intake history was not checked because with low possibility of causing factor. Conclusions : This outbreak appear to be closely related to drinking not sterilized spring water when participating in a religious meeting. However, actual route of transmission was not defined because the epidemiological survey was started six days after the first attack, and, could not find the causative agent in the spring water. The prompt epidemiological survey thought to be essential and important when occurred episode. And also, cooperation with the corresponding health authorities would be very important when the outbreak occurred distant area as this episode. Personal and public concerns and efforts should be sustained to prevent the outbreak and spread-out of Bacillary dysentery.

아동기의 비밀에 대한 현상학적 이해: 문학 작품을 중심으로

홍계숙,유혜령 한국교육인류학회 2001 교육인류학연구 Vol.4 No.1

소아 급성 부비동염의 진단에 Water's view촬영이 충분한가?

홍현숙,이혜경,박재옥 순천향의학연구소 1996 Journal of Soonchunhyang Medical Science Vol.2 No.2

The purpose of this study was to examine the utility of the Water's view in the diagnosis of acute sinusitis in children. The records of all pediatric patients who underwent sinus radiography for suspected acute sinusitis between Oct. 1995 and Apr.1996 was reviewed. All radiographs were reviewed by an attending radiologist and the interpretation of the Water's(occipitomental) view alone was compared to that of a 3 view PNS series(AP Caldwell, lateral, Water's view). 86 PNS series were obtained on 76 pediatric patients during the study period. When compared to 3 view series, the single Water's view had a sensitivity of 84%, specificity is 79%, positive predictive value of 87%, negative predictive value of 84%, overall accuracy of the Water's view in diagnosing childhood acute sinusitis was 85%. The authors conclude that the Water's view is usually sufficient in the evaluation of suspected acute sinusitis in children.

간질발작후 MRI 영상에서 뇌 종창을 보인 3예 보고

홍현숙,김대호,이혜경,박재성,박성진,조준희,차장규,백상현 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

We report seizure induced brain swelling in three patients. MRI revealed a cortical, subcortical(3/3), and basal ganglia(2/3) high signal intensity on T2- weighted and FLAIR images. The lesion shows low signal on T1-weighted image, and enhanced after contrast administration. Follow up study after 27 days in one case revealed complete resolution of the lesion. The reversible MRI findings may be the results of a local brain swelling, breakdown of blood-brain permeability, and a defect of cerebral autoregulation during seizure activity. The transient nature of such findings have to be considered in the differential diagnosis such as reversible ischemia, migraine, inflammation and infection.

Nifedipine 투여가 선천성 고혈압 쥐의 CYP1A1과 2B1 유도에 미치는 영향

홍영숙,김형래,박혜영,배영숙,박상신 梨花女子大學校 醫科大學 醫科學硏究所 1995 EMJ (Ewha medical journal) Vol.18 No.3

Cytochrome P-450(CYP) enzymes are important in catalyzing the hiotransffrmation on manyendogeneous compounds and xenobiotics, including drugs and carcinogens. In the presentstudy, effect of nifedipine a voltage dependent calcium channel blocker on the induction ofCYP1A1 and 2B1 was investigated. Change of CYP1A1 and 2B1 activities were measuredby using specific enzyme activities and Western blot analysis. CYP1A1, as quantified by ethoxyresorufin-0-deethylase activity and Western blot with monoclonal antibody 1-7-1, increasedin liver microsome of nifedipine-treated spontaneous hypertensive rat(SHR. 30mg/kg.b.w, twicea day for 3days) but not in kidney microsome. CYP2B1, as quantified by benzyloxyresorufin-O-dealkylase activity and Western blot wit]1 monoclonal antibody 2-66-3, markedly increasedin liver microsome of nifedipine-treated SHR but slightly in kidney microsome. The resultsdemonstrate that nifedipine is a potent inducer of CYP2B1 in SHR.

고등학생의 성 관련 특성, 성 지식에 관한 기초 조사

김혜원,김남순,윤태호,김종숙,홍경자 관동대학교 의과대학 의과학연구소 2005 關東醫大學術誌 Vol.9 No.1

Purpose : This preliminary study was done to identify sex related characteristics and sex knowledge of high school students. Methods : 622 high school students participated in the survey living in Gangreung city area. The data collection was done from May 1st to October 31st, 2000 using the self administered questionnaires. Results : The teachers and the peer students had a critical position in high school sex education. Reproductive physiology such as relations with the opposite sex, AIDS, STI, and contraceptions should be intensified in further sex education for high school students. There were sex differences in contraception and permission with sex relationship. And the false belief regarding sex assaults and knowledge deficit in AIDS were discovered. Conclusion : Sex education program development and application are necessary based on the educational needs and attitude evaluation for the sexual health improvement of high school students. In further study, developing the reliable measurement tool and various educational methodologies will be studied which are enough for the include the sex education concepts.

전위된 상악 견치 및 하악 측절치의 치험례

권해숙,현홍근,김영재,김정욱,장기택,김종철,한세현,이상훈 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.4

Tooth transposition is an anomaly of eruption characterized by the interchanged positions of two adjacent teeth, which is divided into complete and incomplete transposition. There are three common approaches for treating transposition: aligning the involved teeth in their transposed positions, moving them to their correct anatomic position in the arch and extracting one of the transposed teeth. Considerations in treatment plans are esthetic, function, risk of jeopardizing the roots and damaging the supporting structures, position of the root apex, developmental stages of teeth and expected compliance. The presented case reports described one maxillary canine-the first premolar transposition and two mandibular lateral incisor-canine transpositions. The former transposed teeth were arranged in their transposed position, and the latter transposed teeth were rearranged into their normal position. 치아전위란 인접한 두 치아의 위치가 서로 바뀐 치아 위치 이상을 말하며, 치관과 치근의 위치에 따라 완전전위와 불완전전위로 나눌 수 있다. 하악보다는 상악에 편측성으로 호발하며, 특히 상악 견치에서 자주 발생한다. 전위는 발견 시기와 전위된 양상에 따라 치료방법이 달라질 수 있다. 본 증례는 상악 견치와 제1소구치 간의 전위가 일어난 10세 7개월의 환아와 하악 측절치와 견치 간의 전위가 일어난 8세 11개월 환아와 8세 9개월 환아의 교정치료에 대한 것으로 양호한 치료 결과를 얻었고, 증례 별로 치료방법의 차이점에 관한 고찰을 하였기에 이를 보고하는 바이다.

유치 수복물에 따른 주변 법랑질의 탈회 저항성 : QLF를 이용한 연구

권해숙,현홍근,김영재,김정욱,장기택,김종철,한세현,이상훈 大韓小兒齒科學會 2010 大韓小兒齒科學會誌 Vol.37 No.1

본 연구에서는 유치 수복물의 불소 방출 여부에 따른 주변 법랑질의 탈회 저항성과 재광화 효과를 살펴보고자 하였다. 건전 유전치 48개를 16개씩 임의로 세 군으로 나누어, FiltekTM Z250(1군), F2000(2군), KetacTM N100(3군)을 사용하여 제조사의 지시에 따라 충전하였다. 3일 동안 인공 우식 병소를 유발한 후, 14일 동안 인공 타액에 담가 재광화를 유발하였다. Quantitative light-induced fluorescence(QLF)를 이용하여 실험 단계와 시간에 따른 무기질 소실량(ΔQ)의 변화를 관찰한 결과는 다음과 같다. 1. 탈회가 일어난 인공 우식 병소의 ΔQ 값은 3군, 2군, 1군 순으로 작게 나타났고, 이 중 3군은 1군에 비해 유의한 탈회 저항성을 보였다. 2. 1군, 2군, 3군 모두 재광화 1일 후부터 초기 인공 우식 병소의 ΔQ 값과 비교 시 유의한 차를 보였으며, 관찰 기간 동안 지속적인 증가 양상을 나타내었다. 3. 재광화 속도를 의미하는 Δ(ΔQ)/일 값은 각 군에서 처음 1일 동안 유의성 있게 크게 나타났으며, 그 이후 급속히 감소하였다. 4. 수복 재료에 따른 재광화 정도는 각 군 간에 유의한 차이가 없었다. The objective of this in vitro study was to detect and monitor demineralization and remineralization of primary teeth according to restorative materials using quantitative light-induced fluorescence (QLF). A single bur hole was drilled on the each sound forty eight primary anterior teeth, and the specimens were divided into three groups. The cavity was restored with FiltekTM Z250(Group 1), F2000(Group 2), KetacTM N100(Group 3) following the manufacturer's instructions. The teeth were subjected to the demineralizing buffer for 3 days, and then subjected to a remineralizing buffer for 14 days. The change of mineral loss(ΔQ) according to the stages was evaluated by QLF and the following results were obtained: 1. When demineralization was done, ΔQ was increased as follows. : Group 1 (-110.79 ± 27.77) < Group 2 (-104.84 ± 28.95) < Group 3 (-90.16 ± 21.87) : Resistance to demineralization was statistically significant in Group 3. 2. There was a statistically significant increase in ΔQ of all groups since 1st day of remineralization 3. The rate of remineralization, Δ(ΔQ)/day, showed significant high value in each group on the 1st day then decreased rapidly. 4. There was no statistically significant difference in the degree of remineralization among restorative materials.

서울 集團住宅 地域의 地域性

金敬淑,洪惠善 梨花女子大學校 師範大學 社會生活科 1964 綠友硏究論集 Vol.- No.6