十二變에 대한 考察 : 六元正紀大論을 중심으로

채영진,남호현,이석모,여성원,한성규,이재원,안민식,정헌영,금경수 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1

The six kinds of natural factors(It refers to wind, cold, summer-heat, dampness, dryness and fire.) is constantly moving to maintain the balance of whole climate of one year. Four seasons are the largest mediation of whole climate of one year. The cold and the heat have the relationship of mutual intervention. The dampness and the dryness have it also. In this process they raise various climate appearance. And that various climate appearance influence the whole lives on the earth. This paper is concerned with the classification of them.

Superconducting MgB2 Wire Drawing Considering Anisotropic Hardening Behavior and Hydrostatic Effect

Young‑Seok Oh,Ho Won Lee,Kook‑Chae Chung,Duck‑Young Hwang,Seong‑Hoon Kang,Jeong Whan Yoon 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.7

Numerical modeling was conducted to investigate the deformation behavior of powder mixture during multi-pass drawingprocesses for multi-filamentary MgB2wire. A modified Drucker-Prager Cap (DPC) model with an elliptical cap surface usingthe new material characterization method was developed to capture the anisotropic hardening behavior and hydrostatic effectof the powder mixture. A number of uniaxial die compaction, cold isostatic pressing, diametrical compression, and uniaxialcompression tests were conducted using different powder densities to characterize the modified DPC model. A commercialfinite element software ABAQUS with a user subroutine was used to simulate the drawing of the MgB2wire. The densityand area fraction of the powder mixture during the wire-drawing process were verified with experimental results. The differencein packing density at the inner and outer filaments of the MgB2wire was successfully captured by simulation. Inaddition, the effect of the initial packing density on the superconducting properties of MgB2wire was numerically studied. It is shown that the increase in the superconducting area, which results from a high initial packing density, should be moreeffective compared to the increase in the grain connectivity in enhancing the critical current properties for the MgB2wirewhen the final packing density is saturated after a number of drawing processes.

用寒遠寒과 用熱遠熱에 대한 考察 : 六元正紀大論에서

채영진,신창환,임현택,여성원,한성규,이재원,정헌영,금경수 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1

Five elements motion and six kinds of natural factors influence not only human disease but also difference of medicine effect. Because the climate of summer is very hot, that is easy to increase the properties of hot medicines, a doctor must be careful to use it in summer. Also the climate of winter is very cold, that is easy to increase the properties of cold medicines, a doctor must be careful to use it in winter. But in the certain conditions to use diaphoretics or purgatives, in spite of that regulation a doctor can use them.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

야간 환자 발생양상에 관한 조사연구

원광연,심운택,조영채 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.2

This study was conducted with 800 patients, who came to the emergency rooms of hospital and clinic at night time of Cheongju medical bloc, to look for the characteristics of the occurance of: emergency patients at night time, for randomly sampled 7 days containing each different day from April 1st. to April 30th. 1987 on the basis of such various factors as age, sex, residence and status of patients. The following conclusions were obtained 1. The percentage of emergency patients by sex were 60.1% in male and 33.9% in female, making the ratio 1.54 : 1. The age group of 10s and 20s occupied 40.3% of all patients. 2. The percentage of each disease was 41.1% in injury and poisoning, 17.2% in disease of the respiratory system, 16.1% in disease of the digestive system. 3. Male had a higher incidence in the injury and poisoning, disease of the respiratory system, infectious and parasitic disease, but disease of the digestive system, disease of the nervous system and sense organ, complication of pregmancy, child birth and the p lerperium were higher in female. 4. Age distribution of emergency patients showed as followes : Injury and )oisoning had a higher percentage in the age group of 10-49 years, disease of respiratory system under 1 years of age, disease of the digestive system over 30 years of age, disease of circulartory system in 40-50 years of age. 5. Disease distribution on residential area revealed that residents out of city had higher propor tion of injury and poisoning, infectious and parasitic disease than the ones in city. The time of staying in the emergency room were less than 1 hour in 69% of all patients. 6. The status of patients when leaving the emergency room were complete cure(68.7%), admission(17.9%) self-discharge (12.5%), and death(0.9%).

중년여성의 연령별 체력 비교

원영두,송채훈,안용덕 朝鮮大學校 스포츠科學硏究所 2005 스포츠科學硏究 Vol.16 No.-

This study measured physical fitness with 282 middle-aged women between 30 and 59, living in G metropolitan city who have no abnormality as a result of physical examination with a view to develop standardization method of health and strength factors by age and model of converting such factors into health age measures and obtained the following conclusions. In comparison of physical fitness by age. there were statistically significant differences in grip strength, sit-up, side step, reaction time. trunk extension, sargent jump. close eyes foot balance, Vo2max, and subjects in their thirties showed higher scores in physical fitness measurement and the older they are, the lower their strength.

수면 무호흡과 불안장애의 불면증에 대한 다원수면기록

채정호,박원명,채영래,김제헌 大韓神經精神醫學會 1994 신경정신의학 Vol.33 No.2

Objects : The authors studied polysomnographic findings of patients with sleep apnea DIMS (disorders of initiating and maintainig sleep) syndrome and anxiety disorders with insomnia related to another mental disorders. Methods : Eight patients with sleep apnea DIMS syndrome and fourteen patients with anxiety disorder with insomnia related to another mental disorder(nonorganic) were studied using computerized polysomnography. Results : 1) The sleep period time were significantly decreased in anxiety disorder group and the sleep latency was prolonged in these patients. 2) The changes in sleep stage and the number of arousals during sleep period time were more frequent in sleep apneic patients group. And using these variables we could discriminate sleep apneic patients group from subjects with anxiety disorder. 3) The stage 1 sleep was significantly increased in sleep apneic patients. 4) The apnea index in sleep apnea patients was 28.1±25.7. Conclusion : These results suggested that even though there were similiar clinical presentaion such as insomnia, the sleep features of sleep apnea DIMS syndrome and anxiety disorder with insomnia were different. And though there were no instruments to check respiratory flow or movement, it would be possible to discriminate the sleep apnea DIMS syndrome from the anxiety disorder with insomnia by recording the changes in sleep stage and the number of arousals in overnight electroencephalographic procedure.

가족성 고콜레스테롤혈증 유병자에서 HMG Co-A Reductasen Inhibitor 및 Bile Acid Resin의 투여로 인한 아킬레스건 황색종의 감소

채인호,한기훈,박영배,조주희,김효수,손대원,김철호,오병희,이명묵,최윤식,서정돈,이영우 대한순환기학회 1997 Korean Circulation Journal Vol.27 No.9

중년남성의 12주간 운동유형별 트레이닝이 신체구성 및 건강관련체력에 미치는 영향

원영두,송채훈,신명건 朝鮮大學校 스포츠科學硏究所 2004 스포츠科學硏究 Vol.15 No.-

This study applied aerobic and non-aerobic exercises to middle-aged men for 12 weeks, suggested effective exercise types based on its influences on their physical composition and physical fitness and aimed at providing the information to prevent adult diseases. It selected total 50 subjects including 25 aerobic exercise group and 25 non-aerobic exercise group at sports center in G metropolitan city, calculated the mean and standard deviation using statistical program SPSS 11.0 after 12-week training, conducted t-test (paired sample t-test) for differential test before and after exercise and obtained the following conclusions. 1. In the changes of physical forms by exercise types, aerobic exercise group showed statistically significant differences at chest (p<.05). waist (p<.01) and hiP (O<.05) before and after exercise and non-aerobic exercise group showed statistically significant differences at waist, hip and thigh sizes as P <.05 level and then it was found that aerobic and non-aerobic exercises have the influence on the changes of physical forms. 2. In the changes of subcutaneous fat thickness by physical parts according to exercise types, aerobic exercise group showed statistically significant differences at all subcutaneous fat thickness including triceps, subscapular, abdominal, Iliac crest, medial calf, etc. (p<.Ol), but non-aerobic exercise group showed statistically significant differences at all parts excluding medial calf (p<.05) 3. In the changes of health related physical strength by exercise types, there were statistically significant differences at muscular strength, muscular endurance, flexibility and cardiopulmonary endurance (p<.OOl). According to the above conclusions, it was found that aerobic and non-aerobic exercises had the influence on changes of physical composition, sizes and subcutaneous fat thickness and they were very effective in health related physical strength factors.

직장남성의 연령 및 비만별 체력비교

원영두,송채훈,조완주 朝鮮大學校 스포츠科學硏究所 2004 스포츠科學硏究 Vol.15 No.-

This study examines the physical fitness of each factor needed by working men, seeks to improve their physical strength by age and the degree of obesity, prevent several diseases due to the lack of exercise in advance, improve their service efficiency, enjoy efficient leisure activities and develop exercise programs for diagnosing physical strength and improving health. It calculated the mean and standard deviation by age and obesity (BMI) using statistical program SPSS 11.0 with 702 working men and obtained the following conclusions from post-test using one-way ANOVA and scheffe for differential test of the mean between groups. 1. In compahson of physical fitness factors by age, the group below 29 years old showed higher physical fitness level than other age groups in muscular strength, muscular endurance, flexibility, equilibrium, agility, power, whole body reaction and cardiopulmonary endurance and in comparison between groups by age, there was statistically significant difference at all physical fitness factors as p<.001. 2. In comparison of physical fitness factors by obesity, underweight group showed higher physical fitness level at muscular endurance, agility, equilibrium and flexibility factors, normal weight group showed higher physical fitness at power and whole body reaction factors and obesity group showed higher physical fitness at muscular strength factor. In addition, as a result of comparing physical fitness factors among groups by obesity, there was statistically significant difference at muscular strength, agility, Power, flexibility and cardiopulmonary factors as p<-05.