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      • Helicobacter Pylori Prevalence in Chronic Liver Disease Patients by Using 14CUrea Breath Test

        ( Bayarjargal Altankhuyag ),( Nyam Biziya ),( Munkhtur Dandar ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1

        Aims: Helicobacter pylori are one of the major etiologies for stomach diseases in the Mongolian population. H. pylori infection prevalence is ranged 70% to 80% in adults, 60% in gastric cancer patients and around 70% in children. In Mongolia, the diagnosis of H.pylori infection is performed by using invasive (endoscopic biopsy for histopathology, culture, and rapid urease test) and noninvasive (stool antigen test, and serological tests) methods. Methods: We enrolled in this cross-sectional study 168 chronic liver disease patients with at the Internal Medicine Department of Dornod Medical Center, 2018 to August 2019. The patient had drunk one urea C14 capsule with 30 to 50 mL water. After 15 minutes the patient blowing into the breath collecting cart until the cart’s orange dot getting yellow. Then breath collecting cart inserted to the device and estimated the number of detecting Helicobacter. We use Microsoft Excel, SPSS (ver. 20.0) program for Statistical analysis. Results: Total number of collected cases were 168, among of them 72 (42.85%) were male and 96 (57.14%) women, mean age was 36.42 years. 14C-UBT was positive in 151 patients (89.88%) and negative in 17 patients (10.11%). Active H. pylori infection were very high 55 patients (32.73%) among ≤29 aged people, 43 patients (25.59%) in 30 to 39 years, 21 patients (12.5%) in 40 to 49 years, 18 patients (10.71%) for 50 to 59 years and 14 patients (8.3%) for 60 years older people. 14C-UBT average results were 232.54, the highest result were 1,169 and the lower result was 5. During the evaluation of 14C-UBT results we could not find false negative results. Conclusions: The prevalence of active infection of H. pylori was high in chronic liver disease patients, especially among 20 to 39 years old adults compared to other participants.

      • Vitamin D Deficiency in Chronic Liver Disease patients

        ( Uranbaigali Dashnyam ),( Bayarjargal Altankhuyag ),( Nyam Biziya ),( Shinebayar Narantuya ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1

        Aims: One of the most nutritional deficiency in the world is the deficiency of 25-hydroxyvitamin D [25(OH)D]. Study assessed that there are more than 1 billion people living in the world that has serum 25(OH)D<20 ng/ml deficiency. Vitamin D deficiency is widespread in individuals irrespective of their age, gender, race and geography. Deficiency of 25(OH)D not only causes children’s arthritis but to a range of common chronic diseases in adulthood such as diabetes, cancer, infectious diseases, cardiovascular disease, and autoimmune disease, this continuous to be a major public health problem in the world. Methods: Study participants were 102 chronic liver disease over the age of 18 from the citizens of “Choibalsan” city, “Dornod” province, who were referred to the outpatient of Dornod Medical center, Dornod, Mongolia. Overnight fasting blood samples were collected. All patients had tests for blood 25(OH)D were measured by ELISA and 28 patients who took 6 questionnaire tests. Results: Of all patients, 66 were men (68.1%) and 34 were women (31.9%). The mean age was 46 (between 18 and 89 years). There were 55 patients with cirrhosis (54%), and were 47 patients with chronic hepatitis B and C in the study group. 94 (92%) participants had 25(OH)D<20 ng/ml deficiency. Age and season had no correlation on the 25(OH)D level. From the results of the questionnaire test we can see that 5 have efficient 25(OH)D, 17 had the possibility of deficiency of 25(OH) D, and 6 had to reapply for the tests but these participants had 25(OH)D<10 ng/ml and this has no relevance on the level 25(OH)D (Pearson r=0.07, P=0.5). Conclusions: In conclusion, our pilot results show that patients as in 92% have 25(OH)D deficiency.

      • Vitamin D Deficiency in Chronic Liver Disease patients

        ( Nyam Biziya ),( Bayarmaa Nyamaa ),( Bayarjargal Altankhuyag ),( Shinebayar Narantuya ),( Borkhuukhen Derem ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

        Aims: One of the most nutritional deficiency in the world is the deficiency of 25-hydroxyvitamin D [25(OH)D]. Study assessed that there are more than 1 billion people living in the world that has serum 25(OH)D<20 ng/ml deficiency. Vitamin D deficiency is widespread in individuals irrespective of their age, gender, race and geography. Deficiency of 25(OH)D not only causes children’s arthritis but to a range of common chronic diseases in adulthood such as diabetes, cancer, infectious diseases, cardiovascular disease, and autoimmune disease, this continuous to be a major public health problem in the world. Methods: Study participants were 102 chronic liver disease over the age of 18 from the citizens of “Choibalsan” city, “Dornod” province, who were referred to the outpatient of Dornod Medical center, Dornod, Mongolia. Overnight fasting blood samples were collected. All patients had tests for blood 25(OH)D were measured by ELISA and 28 patients who took 6 questionnaire tests. Results: Of all patients, 66 were men (68.1%) and 34 were women (31.9%). The mean age was 46 (between 18 and 89 years). There were 55 patients with cirrhosis (54%), and were 47 patients with chronic hepatitis B and C in the study group. 94 (92%) participants had 25(OH)D<20 ng/ml deficiency. Age and season had no correlation on the 25(OH)D level. From the results of the questionnaire test we can see that 5 have efficient 25(OH)D, 17 had the possibility of deficiency of 25(OH) D, and 6 had to reapply for the tests but these participants had 25(OH)D<10 ng/ml and this has no relevance on the level 25(OH)D (Pearson r=0.07, P=0.5). Conclusions: In conclusion, our pilot results show that patients as in 92% have 25(OH)D deficiency.

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