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      저자 : ( A K M Sajedur Rahman ) (검색결과 1 건)
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      • Poster Session : PS 0622 ; Others ; Factors Predicting Outcome of Patients with Organophosphorus Poisoning

        ( A K M Sajedur Rahman ),( Mohamamd Robed Amin ),( Titu Miah ),( Ham Nazmul Ahasan ) 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1

        Background: Around two million people dies each year from Organophosphorus pesticide poisoning, principally by self poisoning in Asia-Pacifi c region. Predictors of the factors associated with outcome of patients with Organophosphorus poisoning using various parameter can augment appropriate management tool. Methods: This cross-sectional observational study was carried out from September, 2012 to June, 2013 in the department of Medicine, DMCH. Eighty samples with detailed information`s were obtained in each cases according to protocol from patients or accompanying attendants. Thorough clinical examination was done. International program on chemical safety poison severity score (IPCS-PSS) and Glasgow coma scale (GCS) score was recorded to predict the outcome. Collected data were classifi ed, edited and entered into the computer for statistical analysis by using SPSS version-16 (Inc. Chicago-III) and area under curve (AUC) was observed. Results: Among 80 cases, majority (42.5%)of the patients with Organophosphorus compound were in 3rd decade and male to female ratio was 1.4:1. Regarding nature of various OPCs, Malathion was found 20.0%, diazenon 16.25%, Chlorpyrifos 7.5%, unlabelled OP 17.5% and other OP was 26.25%. GCS and IPCS PSS are good predictor of outcome and area under curve (AUC) found 0.407 with sensitivity and specifi city both of 0.571 and 0.242. The IPCS PSS grade 1 presentation was more frequent which was 71.2%, followed by grade 3 (IPCS PSS) 15.0% and grade 2 was 13.8%. In grade 1 and 2 (IPCS PSS) 71.3% and 13.8% were cured respectively and there was no death. Grade 3 (IPCS PSS) 12.5% were cured and 2.5% were found death. Conclusions: The present study indicated that the IPCS PSS and GCS were found good predictor for mortality. Patients who present with GCS < 13 and IPCS PSS grade 2 and 3 need to be treated accordingly and monitored very closely.

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