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- 저자 : Seungmi Lee (검색결과 83 건)
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대통령의 약속 - 노무현ㆍ이명박ㆍ박근혜 대통령 선거공약 입법산출 연구 -
이승미 ( Seungmi Lee ) 한국정책학회 2019 한국정책학회보 Vol.28 No.3
This article investigates the successful legislative process of the presidential election pledges in the National Assembly. With respect to the importance of policy-oriented elections and manifesto in presidential elections, it is a responsibility both for the president and the electorate to fulfill campaign pledges and to monitor the performance. Therefore, it is a meaningful attempt to illuminate agents influencing the presidential election pledges during legislative agenda-setting and successful legalization. Specifically, this study analyzes the approval of original government bills referring to the presidential election pledges during Roh Moo-hyun, Lee Myung-bak, and Park Geun-hye Administrations. According to Article 52 of the Constitution of the Republic of Korea, which gives the executive branch the right to introduce bills, this paper statistically tests the effect of the presidential election pledges on the approval of original government bills in the National Assembly. The binary logistic regression results illustrate that (1) the presidential election pledge variable has a significant negative effect on the approval of original government bills. (2) The presidential job approval also makes the presidential election pledge variable have a negative effect on the passage of original government bills. However, (3) a honeymoon effect relatively occurs between the presidential election pledge variable and the approval of original government bills when the bills are introduced during the first year in office(a decreasing tendency of the approval of original government bills is mitigated). Lastly, (4) unified government helps the presidential election pledge variable rather decrease the approval of original government bills. A 5-year-single-term presidency can impede the fulfillment of presidential campaign promises, and factional conflicts within the ruling party can also diminish political support towards the presidential election pledge agendas.
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Kim, Jina,Song, Jaeyoung,Ji, Hyun Dong,Yoo, Eun Kyung,Lee, Jae-Eon,Lee, Sang Bong,Oh, Ji Min,Lee, Seungmi,Hwang, Ji Sun,Yoon, Heeseok,Kim, Dong-Su,Lee, Su-Jeong,Jeong, Minseon,Lee, Sungwoo,Kim, Kyung- American Chemical Society 2019 Journal of medicinal chemistry Vol.62 No.4
<P>An inverse agonist of estrogen-related receptor-γ (ERRγ), an orphan nuclear receptor encoded by E<I>srrg</I>, enhances sodium iodide symporter-mediated radioiodine uptake in anaplastic thyroid cancer (ATC) cells, thereby facilitating responsiveness to radioiodine therapy in vitro. We synthesized potent, selective, and orally bioavailable ERRγ-inverse agonists and evaluated their activity by analyzing in vitro pharmacology and absorption, distribution, metabolism, excretion, and toxicity profiles. X-ray crystallographic analysis of the ligand and ERRγ complex showed that <B>35</B> completely binds to the target protein (PDB 6A6K). Our results showed improved radioiodine avidity in ATC cells through compound <B>35</B>-mediated upregulation of iodide-handling genes, leading to enhanced responsiveness to radioiodine therapy in vitro. Importantly, in vivo <SUP>124</SUP>I-positron emission tomography/computed tomography imaging revealed that <B>35</B> increases radioiodine avidity in CAL62 tumors. Collectively, these results demonstrated that <B>35</B> can be developed as a promising treatment for ERRγ-related cancer in the future.</P> [FIG OMISSION]</BR>
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An Acoustic Analysis on the Plosives of Korean and Japanese
Lee Seungmie The Korean Society Of Phonetic Sciences And Speech 1992 말소리 Vol.21 No.-
본 논문에서는 한국어에 있어서 세 가지 유형의 파열음과 일본어에 있어서 두 가지 유형의 파열음과 일본어에 있어서 두 가지 유형의 파열음이 보여주는 시간적 특성을 어두 위치 및 모음간 위치로 나누어 비교해 보았다- 한국어에 있어서 세 가지 유형의 파열음은 어두 위치에서 모두 무성음으로 실현되므로 성의 대립으로는 이들을 유형화 할 수 없고, 그보다는 조음의 힘과 기식의 유무에 따라 연음, 무기 경음, 유기 경음으로 분류하는 것이 타당하다. 이에 비해 일본어 파열음은 유성음인 연음과 무성음인 경음의 두가지 유형으로 대립된다. 유성음과 무성음, 그리고 유기음과 무기음의 구분에는 파열음의 개방에서부터 성대 진동까지의 시간인 성 시작 시간(VOT)과 기식의 길이가 변수가 된다. 경음과 연음의 구분에는 선행 모음의 길이, 폐쇄 지속 시간, Vl/(Vl+CL)의 비율이 유용한 정보가 된다. 양국어 어두 파열음의 VOT를 비교해 볼 때, 일본어 유성음은 음수의 VOT를 가지며, 한국어 무기 경음에서는 VOT가 10msec정도로 짧게 나타나고, 그 다음으로 한국어 연음. 일본어 무성음, 한국어 유기 경음의 순서로 길어진다. $\frac{선행 모음의 길이}{(선행 모음의 길이+폐쇄 지속 시간)}$의 비율은 언어의 특성도 반영해 주는데, 한국어의 경우 연음: 무기 경음: 유기 경음의 비는 0.63: 0.30:0.35, 일본어의 경우 유성음:무성음의 비는 0.69: 0.45로 나타났다. 청취 실험을 통해 한국인의 자음 인식 경향을 살펴본 결과, 성대 진동의 유무를 변별적으로 사용하지 않는 한국인 화자는 일본어 유성음은 연음으로, 무성음은 경음으로 인식하는 경향이 있는 것으로 나타났다.
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Seungmi Lee,HeeJin Hwang,Hyejin Jung,Jung-Ho Kang 대한지질학회 2021 대한지질학회 학술대회 Vol.2021 No.10
Polar snow and ice are essential research materials to reconstruct past climate change as those preserve the Earth"s atmospheric composition. To measure trace elements in snow and ice samples from the polar regions, we have to keep the clean protocol and maintain the water quality for low blank levels below sub picogram per gram or femtogram per gram level. We periodically check whether the water quality is maintained as well as the maintenance of a clean laboratory. In this study, we have tested the pre-concentration methods: heating evaporation method, graphite heating method, and vacuum freeze-drying method to confirm the water quality. Heating evaporation method concentrated sub-boiling water in a Teflon beaker at 100℃ using an aluminum heating block. The graphite heating method concentrated sub-boiling water in a Teflon bottle at 80°C using a graphite heating block. In vacuum freeze-drying method, sub-boiling water in a LDPE bottle was frozen at -60°C, and then freeze-dried at a pressure of 0.350 mbar. We have measured trace elements in the concentrated water samples using an inductively coupled plasma-sector field mass spectrometry (ICP-SFMS). This fundamental research method will establish a reliable and stable methodology to control the water quality for the analysis of trace elements in polar snow and ice.
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Seungmi Lee 한국학술연구원 2021 Korea Observer Vol.52 No.3
This article explores the two competing democratic concepts of liberalism and political equality in Korean politics. In the development of Korean democracy, liberalism has evolved as a form of anticommunism as a way to pursue social stability; meanwhile, political equality has emerged by means of civic participation as a way to seek equal opportunities to be involved in decision making. This article traces how political equality has tended to expand from the time of Kim Young-sam to the Roh Moo-hyun administrations, while liberalism dominated during the administrations of Lee Myungbak and Park Geun-hye. In addition, this article identifies different trends of civic participation between the progressive governments that promoted civilian ascendancy and the conservative governments that showed uncommunicative leadership in the decision-making process.
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Drop on demand electro-hydrodynamic printing induced by square pulse voltage signal
Seungmi Lee(이승미),Junyoung Song(송준영),Jaewon Chung(정재원) 대한기계학회 2011 대한기계학회 춘추학술대회 Vol.2011 No.10
Electro-hydrodynamic(EHD) printing is receiving a huge interest due to its high resolution printing capability along with many advantages such as reduced manufacturing steps and non-toxic, flexible processes. However, many issues are yet to be resolved to realize high volume fabrication process. In this work, to demonstrate high resolution EHD printing on demand, square pulse voltage signals are applied between a hole-type electrode and a nozzle where working fluid is supplied from a reservoir at constant pressure. By varying voltage signals and hydrostatic pressure applied to the nozzle, a change in jetting start time is observed. Also, continuous, fine jet pulsating, and droplet pulsating mode are observed as the voltage signal induced varies. Of all modes, the behavior of droplet pulsating mode with various voltage signals is studied and optimized voltage signal is demonstrated.
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