검정금파리의 第二生殖週期 誘導

李鍾鎭,李熙權,李敬魯 全北大學校 1991 論文集 Vol.33 No.-

Induction of the second reproductive cycle and ovarian maturation, and changes of protein were investigated in the black blowfly, Phormia regina. A height in between hardboard and bottom of the experimental device based on the length of mouthpart and ovipositor was 2.5cm. Ovipositional rate of the first reproductive cycle in the experimental device was 81.2±6.1% without liver juice in the crop and midgut. During the second reproductive cycle terminal oocyte was 385, 977, 1121㎛ and ovary was 1732, 3819, 3946 ㎛ in length at 24, 48, and 60h after the second liver-feeding, respectively. Haemolymph protein increased 36h after the second liver-feeding and decreased thereafter while ovarian protein increased continuously until 60h in the second reproductive cycle. This result should be applicable as reference data for the embryo-physiological research of the second reproductive cycle in other Dipteran insects.

NIHSS 활용을 통한 뇌졸중 환자 간호의 질향상 전략

박경현,송경애,공혜성,나화주,유수경,박소영,김상희,최혜림,배희준,한문구,양미화 한국의료QA학회 2009 한국의료질향상학회지 Vol.15 No.2

문제: 뇌졸중 환자를 돌보는 간호현장에서는 급성기 뇌졸중 환자의 증상악화에 대한 조기사정과 적절한 대처가 매우 중요한 문제이다. 그러나 임상현장에서는 이를 객관화하고 수치화하여 모든 의료진이 의사소통할 수 있는 유용한 도구를 사용하고 있지는 못하는 실정이다. 이러한 문제를 해결하기위해 NIHSS(National Institute of Health Stroke Scale)를 신경과 진료의사를 중심으로활용하고 있지만 아직 간호현장에서는보편적으로사용하지 않고있다. 이에 뇌졸중환자간호에 NIHSS를 활용하여 뇌졸중 증상악화의 조기사정과 빠른 대처로 궁극적으로는 뇌졸중환자 간호의 질을보다 향상시키기 위하여 본활동이 시도되었다. 목적: 첫째, 간호사의 NIHSS 측정 신뢰도의 현수준을 점검하고 이를향상시키기 위한 프로그램을 개발·적용한다. 둘째, 간호사가급성기 뇌졸중환자에게 NIHSS 측정을 통하여 뇌졸중악화를 얼마나 예측할 수 있는지 분석하고 이를 향상시킬수있는 방법을 모색한다. 셋째, 궁극적으로 급성기 뇌졸중 환자의 증상악화의 조기 발견과치료를위한의료진의 올바른 대처지침을 마련하여 이를 적용한다. 의료기관: 경기도에 소재한 대학병원의 뇌졸중 집중치료실 질 향상 활동: 첫째, 간호사의 NIHSS 측정 신뢰도 향상을 위해 「NIHSS 간호사 교육 프로그램」을 마련하였다.

정신재활 치료가 정신분열병 환자의 재발율, 입원횟수, 입원일수 그리고 치료 경비에 미치는 효과 : 2년 추적조사 연구

조진석,공지현,김진원,심경순,하준선,김철권,강동호,장정희,변원탄 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.5

목 적 : 사회기술훈련, 환자교육, 가족교육, 집단치료, 예술치료, 작업치료와 같은 포괄적인 정신재활 치료를 약물치료와 병행할 경우 약물치료만 시행할 때에 비해 정신분열병 환자의 재발율, 입원횟수, 입원일수, 직접 치료경비 등에 어떤 효과가 있는 지를 알아보기 위함이다. 연구방법 : 1993년 9월부터 1995년 2월까지 양산 신경정신병원의 폐쇄병동에서 퇴원한 20∼35세 사이의 정신분열병 환자 173명을 대상으로 46명에게는 6개월동안 정신재활 치료를 시행하였고 127명에게는 통상적인 외래치료만 시행한 후 연구시작 시점을 포함하여 2년동안 양군에 속한 환자들을 대상으로 재발율, 입원횟수, 입원일수, 직접 치료경비 등을 1년 단위로 추적 조사하였으며, 연구시작 시점을 기준으로 전과 후의 매년 평균 입원횟수, 입원일수, 직접 치료경비도 서로 비교하였다. 결 과 : 정신재활 치료를 약물치료와 병행할 경우 약물치료만 시행할 때에 비해 재발율, 입원횟수, 입원일수, 직접 치료비용이 현저히 감소되었다. 그리고 정신재활 치료를 받은 군에서는 치료 전에 비해 치료 후에 재발율, 입원횟수, 입원일수, 직접 치료비용이 유의하게 감소하였지만 통상적인 외래치료만 받은 군에서는 치료 전과 후간에 유의한 변화를 보이지 않았다. 결 론 : 정신분열병 환자들에게 정신재활 치료를 약물치료와 병행할 경우 약물치료만 시행할 때에 비해 환자의 임상적 경과를 호전시킬 뿐 아니라 가족의 경제적 부담도 줄일 수 있다. Objective : We evaluated the clinical efficacy of a comprehensive psychiatric rehabilitation of schizophrenia, including family psychoeducation, patient education, social skills training, group psychotherapy, art therapy, and occupational therapy. Method : From September 1993 to February 1995, 173 chronic schizophrenics who met DSM-IV criteria and were discharged from a locked ward were assigned into the psychiatric rehabilitation service group(psychiatric rehabilitation group, n=46) or the customary out-patient service group(out-patient group, n=127) prospectively, but not randomly. Assignment was based on preferences of patients and their relatives, Each subject included in the psychiatric rehabilitation group received twice weekly patient education, social skills training, family psychoeducation, group psychotherapy, art therapy, occupational therapy and maintenance chemotherapy during a 6-month period. Those in the out-patient group received individual supportive psychotherapy and maintenance chemotherapy according to their clinical needs for 10-20 minutes once per week. After entry into the study, all subjects were assessed for the number of readmission, days of hospitalization, and the direct treatment costs through the first and second year of follow-ups. These outcome variables were also compared pre-and post-2 years at the time point of entry into the study. Aftercare chemotherapy on a weekly to monthly basis continued for the remainder of the two year follow-up period. Results : With regard to the mean number of hospital admissions per year, the mean days of hospitalization per year, and the direct treatment costs per year, the psychiatric rehabilitation group had significantly decreased all clinical outcomes 2 years after compared with before receiving psychiatric rehabilitation. But there were no significant differences in the all clinical outcomes between before and after study intake in the out-patient group. For the number of relapse regardless of drug compliance, 4 patients(9%) during first year and 14 patients(30%) during second year were relapsed in the 46 subjects of the psychiatric rehabilitation group. In contrast, 75 patients(59%) during first year and 90 patients (71%) during second year relapsed in the out-patient group. When considering the effect of drug noncompliance to relapse, 4(9%) and 14 patients(30%) were relapsed while on medication respectively during the first and second year in the 46 of the psychiatric rehabilitation group, vs. 27(34%) of 79 patients on medication during the first year and 31(46%) of 68 patients on medication during the second year were relapsed in the out-patient group. Conclusions : These results indicate that the comprehensive psychiatric rehabilitation can be useful therapeutic intervention both to improve the clinical outcomes of schizophrenic patients and to reduce the economical burden of their relatives.

온라인 필기인식에 관한 방법연구와 이를 활용한 응용프로그램 제작

윤상인;유진식;공희경;김흥식 인제대학교 2012 仁濟論叢 Vol.27 No.1

Recently with the spread of smart phones is increasing the importance of handwriting recognition technology. Therefore, we studied these online handwriting recognition technology for real-time input. In this research process we study the distance filtering method, the catching feature points, chain code, and similarity matching techniques and make possible the actual coded. We implemented the on-line symbol recognition method which recognize up to 91% of the capital letter. That you can use handwriting recognition to target programs, the children learn to play program planning and production.

입원 환자 영양검색 전산 프로그램 개발

안수미,윤기영,신연명,최경현,임근승,장문경,송윤미,공은희 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

Background : About 30% of patients in the hospital are under nourishment. A large portion of people are undernourished when they are admitted to the hospital and in the majority of these, undernutrition develops further while in hospital. Patient-Generated subjective global assessment(PG-SGA), a method of nutritional assessment based on clinical judgment, has been widely used to assess the nutritional status of adults for both clinical and research purposes. Modified PG-SGA can be used as a nutrition screening tool, and a comprehensive nutrition assessment is desirable for those who are malnourished. The purpose of this study is to develop a simple, reliable and valid nutrition screening program(NSP). Methods : We applied the nutrition screening program(NSP) to adult inpatients who are at risk of malnutrition using the Modified Patient-Generated subjective global assessment(PG-SGA) and objective assessment(electrical medical record data). Results : Therefore simple and beneficial NSP is developed for patients with severe malnutrition. Using NSP. nutritional information of the severe malnutrition patient should be shared with the physicians and they should be taken care of by clinical dietitians to improve their nutritional status. Conclusion : The Modified PG-SGA and nutrition screening tool are simple, reliable and valid nutrition screening program(NSP).

Si Bulk Micromachining을 위한 Wafer Rolling Etching 및 그 특성

김건년,이보나,박효덕,신상모,공경준,장동근,김병철,권혁채,이봉희 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

A wafer rolling etching system for the silicon bulk micromachining has been designed and fabricated. The silicon diaphragms were anisotropically etched in a 24.5 weight percent KOH solution. Compared to the conventional KOH etching systems, pyramidal hillocks, and wave-shaped structures on the etched surfaces were greatly reduced by using this system. After etching for time of 438 minutes, the average etched depth and the etch-rate were measured to be 537μm and 1.22μm/min, respectively. The average etching uniformity of etching depth was 0.87% in 5-inch wafer. Our results showed that the wafer rolling method enhanced etch uniformity and etch rate.

The expression and clinical implication of GAGE gene in Stomach Cancer

Kong, Eun-Hee,Chang, Hee-Kyung 고신대학교 의학부 2005 高神大學校 醫學部 論文集 Vol.20 No.1

배경 : 자가 T 임파구에 의해 인식된 암-특정 유전자 발현을 제외하고 위암에서 GAGE 유전자의 기능에 대한 정보가 아직도 거의 없다. 이 연구는 위암에서 임상적 암시와 암조직발생에서의 기능적인 역할을 밝히기 위해 GAGE mRNA 발현을 평가하기 위한 시도이다. 방법 : 위암 환자 60명으로부터 종양과 비종양 조직을 둘씩 짝을 지어 추출하여 common primer를 가지고 reverse transcription-nested polymerase chain reaction(RT-PCR)을 이용하여 연구하였다. 결과 : 비종양조직에서는 GAGE 발현이 없었다. 60개의 종양 조직으로부터 15개는 GAGE mRNA 발현(25.0%), 13개는 intestinal type(86.7%), 2개만 diffuse type(13.3%)을 나타냈다. 암 조직에서 GAGE 발현은 높은 암의 단계와 림프절 전이에 중대한 영향을 가진다(p<0.05). 그러나 그들은 종양 세포 분화와 혈관, 신경 주위 침범과는 중대한 관계를 보여 주지 않았다. 결론 : GAGE 유전자가 위암의 intestinal type 발생과 진행에 중요한 역할을 하고 GAGE 유전자가 암-특정 면역요법의 유용한 목표 분자일지도 모른다는 것을 암시한다. Background: There is still little information on the function of GAGE gene in the stomach cancer except for cancer-specific gene expression recognized by autologous T lymphocytes. This study attempted to evaluare GAGE mRNA expression to elucidate its functional role in the carcinohistogenesis and clinical implication in gastric cancer. Material and Method: Tumor and non-neoplastic paired samples from 60 patients with gastric cancer were studied by using reverse transcription - nested polymerase chain reaction (RT-PCR) with common primer. Result: No expression of GAGE was observed in non-neoplastic tissues. Fifteen out of 60 tumor tissues expressed GAGE (25.0%) mRNA, of which 13 cases (86.7%) were intestinal type and only 2 cases (13.3%) were diffuse type. GAGE expressions in cancer tissues have a significant tendency to be higher by stage and lymph node metatastasis (p<0.05). However, they did not show significant relationship with tumor cell differentiation and vascular and perineural invasions. Conclusions: This results suggest that GAGE gene might have an important role in the development and progession of intestinal type of stomach cancer and GAGE gene may be a useful molecule for target of cancer-specific immunotherapy.

Accumulation of Sweet Protein monellin is Regulated by the psbA 5`UTR in Tobacco Chloroplasts

( Kyung Hee Roh ),( Kong Sik Shin ),( Yeon Hee Lee ),( Seok Cheol Seo ),( Hyo Guen Park ),( Henry Daniell ),( Seung Bum Lee ) 한국식물학회 2006 Journal of Plant Biology Vol.49 No.1

Security risk assessment framework for smart car using the attack tree analysis

Kong, Hee-Kyung,Hong, Myoung Ki,Kim, Tae-Sung Springer-Verlag 2018 Journal of ambient intelligence and humanized comp Vol.9 No.3

보안인증의 경제적 효과에 대한 연구동향 분석

공희경(Hee-Kyung Kong),전효정(Hyo-Jung Jun),이송하(Song-Ha Lee),강민성(Min-Seong Kang),김태성(Tae-Sung Kim) 한국정보보호학회 2016 정보보호학회논문지 Vol.26 No.3

정보보호 공시제도 도입과 정보통신망법 개정에 따라 ISMS(정보보호관리체계) 인증대상이 확대되어 조직의 보안컴플라이언스 환경이 변화하고 있다. 공시제도와 인증제도 도입을 위해 조직들은 적정수준의 투자를 고려하고 있으나 정보보호관리체계 도입에 대한 경제적 효과나 투자의 범위 및 대상에 대한 의사결정 기준이 명확하게 제시되지 않고 있다. 따라서 본 연구는 정보보호 분야의 각종 인증제도 효과를 분석하기 위한 국내외 연구동향에 대해 조사해보고, 연구된 논문들의 연구주제와 연구방법을 분석하였다. 이를 통해 관련분야 연구 활성화 및 정보보호관리체계 도입을 위한 기초자료 분석에 활용될 수 있을 것이다. This study investigates the domestic and international research trends to analyze the economic effects of various information security certification systems. Results of the study can suggest future research topics for researchers, and help make rational decision-making on introducing information security management systems for practitioners.