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위드 코로나 시대 8주간의 온라인 고강도 인터벌 트레이닝이 과체중 남성의 신체조성, 혈중지질, 사이토카인 및 삶의 질에 미치는 영향
최동훈,현아현 한국운동생리학회 2022 운동과학 Vol.31 No.1
PURPOSE: The purpose of this study is to investigate the effect of high-intensity interval training (HIIT), using real-time video application programs, on the body composition, blood lipids, cytokines, and quality of life (QOL) of over-weight men. METHODS: The participants of this study were overweight men, aged <45 years, who voluntarily applied to the online notices for this study. The men had a body mass index (BMI) >28. Twenty people participated in this experiment and were divided into two groups: a HIIT group (n=10) and a control group (n=10). Both groups were pre-examined to determine body composition, dual-energy X-ray absorptiometry, and QOL indices and also underwent blood tests. The HIIT group underwent high-intensity interval training for 8 weeks (twice a week and 35 minutes per day) using real-time video programs. The main exercise program for HIIT was 20 seconds high-intensity (85–90% HRmax) exercise followed by 30 seconds exercise at a 60% HRmax. RESULTS: Comparison and analysis of the effects observed before and after the exercise revealed that the real-time online HIIT group showed reduced body fat (F=5.690, p=.028). Results of the blood tests showed that the high-density lipoprotein cholesterol (HDL; F=24.584, p=.001) was increased, while the low-density lipoprotein cholesterol (LDL; F=24.963, p=.001), triglycerides (TG; F=7.295, p=.015;), and total cholesterol (TC; F=14.934, p=.001) levels were decreased. No significant effects were observed on the insulin and c-reactive protein (CRP) levels. Finally, the QOL test results showed that the total score of the HIIT group had increased (F=190.815, p=.001). CONCLUSIONS: Online HIIT is a useful method that aids in reducing fat levels in obese men and improving their blood lipid profile and QOL during the COVID-19 pandemic.
Optically Induced Anisotropy in Photoresponsive Sol-Gel Matrix Bearing a Silylated Disperse red 1
최동훈,조강진,차영관,오상준,Choe, Dong Hun,Jo, Gang Jin,Cha, Yeong Gwan,O, Sang Jun Korean Chemical Society 2000 Bulletin of the Korean Chemical Society Vol.21 No.12
We synthesized the simple triethoxysilanes (SGDR1) bearing a disperse red 1 for thin film fabrication. The thin films were prepared using the solution of SGDR1 after hydrolysis and condensation. The films were annealed at two different temperatures such as $150^{\circ}C$ and $200^{\circ}C$. Trans-to-cis photoisomerization was observed under the exposure of 532 nm light with UV-Vis absorption spectroscopy. The kinetic study of photoisomerization was performed in the film. Reorientation of the polar azobenzene molecules induced optical anisotropy under a linearly polarized light at 532 nm. The effect of aggregation of the chromophores and annealing of the silicon oxide in the matrix were studied on the dynamic properties of isomerization and induced birefringence.
최동훈,김재훈 한국안전학회 2019 한국안전학회지 Vol.34 No.5
The mobile elevated work platforms(MEWPs) consist of work platform, extending structure, and car, and it is a facility to move persons to working positions. MEWPs are useful but composed complex pieces of equipments, and accidents are caused by equipment defects. Among them, accidents caused by fracture of the bolts fixing the extension structure and the turntable are increasing. In this study, fatigue failure and fatigue life of a turntable fixing bolt subjected to irregular fatigue load were analyzed by FEA. For this purpose, finite element modeling is proposed and structural analysis and fatigue analysis are performed simultaneously for fixing bolts. As a result of the structural analysis, it was confirmed that there is no risk of permanent deformation because the maximum stress acting on the fixing bolt is lower than the yield strength, and fatigue analysis was confirmed that the fatigue life is less than the design standard. The fatigue analysis results of this study can be effectively used for the design and the documentary assessment of the safety certification of the MEWPs by examining the fatigue life of the turntable fixing bolt.
열수 및 80% 에탄올로 추출한 박하의 생리활성 비교연구
최동훈,승오탁,임미혜 한국응용과학기술학회 2019 한국응용과학기술학회지 Vol.36 No.1
The purpose of this study was to investigated the biological activities such as cytotoxic, anti-oxidant and anti-inflammatory using Mentha arvensis L. extracts. Mentha arvensis L. was prepared by extracting with DW and 80% ethanol, after cell viability was assessed by MTT assay using RAW 264.7 cells. Antioxidant activities, and Anti-inflammatory activities measured through changes in the levels of reactive oxygen species (ROS), nitric oxide (NO), leukotrien B4 (LTB4), and anti- or in-flammatory cytokines(IL-1β, IL-6, tumor necrosis factor (TNF)-α, and IL-10) on LPS-induced RAW 264.7 cells. All test measured by ELISA reader and Luminex. Mentha arvensis L. was no cytotoxic in water and 80% ethanol extracts, and Concentration of 100 ug/ml of 80% ethanol extract was suppressed the productions of ROS in LPS-induced RAW 264.7 cells. Also, Productions of NO, LTB4, inflammatory or anti-inflammatory cytokines showed efficacy change that dose-independent of all extracts. In other words, Mentha arvensis L. showed significant biological activities showing anti-inflammatory, and anti-oxidant. These results may be developed as a raw material for new health food and therapeutics to ease the symptoms mentioned above. 본 연구는 박하 추출물을 통해 독성검사 및 항산화, 항염증과 같은 생리활성을 평가하고자 하였다. 박하 추출은 열수 및 80% 에탄올로 추출하였으며, RAW 264.7 세포를 통해 MTT를 통해 세포 생존율을 평가하였다. 또한, LPS로 유도한 RAW 264.7 세포를 통해 활성산소(ROS), 산화질소(NO), 류코트리엔 B4(LTB 4 ), 항염 또는 염증성 사이토카인(IL-1β, IL-6, TNF-α, IL-10) 등을 ELISA 및 Luminex로 측정하였다. 그 결과, 박하 추출물은 열수 및 80% 에탄올 추출물에서 세포독성이 없었으며, 80% 에탄올 추출물의 100 ㎍/㎖ 농도에서 활성산소의 생성을 억제하였다. 또한, NO, LTB4, 염증 또는 항염증성 사이토카인의 생성을 모든 추출물에서 농도 의존적 효능을 나타냈다. 즉, 박하 추출물은 세포 독성 없이 항산화 및 항염증 활성을 나타내는 생리학적 효능이 나타났다. 이와 같은 결과는 본 연구와 관련된 증상을 개선하기 위한 새로운 건강식품 및 치료제의 원료로 개발될 수 있다.