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丁銓殷,金英哲,朴京鎭,崔種浩 大韓成形外科學會 1975 Archives of Plastic Surgery Vol.2 No.1
There has been a considerable improvement in the understanding of pathophysiology of burn and its treatment in recent year. The mortality for unselected cases of burns has been declined during last few decades. However, mortality from severe burns remains to be very high. In recent journal, several methods has been named to improve this high mortality. One of our effort focused on skin graft to reduce this high mortality. During the past 3 year period from May. 1971 to May. 1974, 224 cases of burn patient had been treated at surgical department of Woo Sok hospital of Korea University. Clinical analysis of these 224 cases of burn patient were carried out and summarized as follows; 1) Age and Sex distribution: Between 1 to 9 years old children were most commonly involved (51.6%) and male were affected twice than females. 2) Sesonal distribution: Most patients were occured in June, July and August, 71 cases (31.7%). 3) The causes of burn are as follows: Scalding 127 cases (56.6%), Flame 78 cases (34.9%), Chemical 12 cases (6%). 4) The extent of burn: 11%∼30% burn surface area is most common, 108 cases (48%). 5) For the fluid therapy of burn cases, Evans formula was employed in most children and Brooke's formula in adult patients. The result of these treatment was excellent in 121 cases (54%) and expired in 58 cases (26%). 6) There were 58 deaths (26%) in all. Among of these, 32 cases(55.2%) were succumbed by the wound infections and septicemia, 8 cases(13.8%) were due to burn shock 7) Skin graft was performed in 48 cases(21.4%). Skin graft was performed mostly between 2 to 3 weeks, as late as 4 weeks. 8) Period from skin graft to discharge was within 2 weeks in 19 cases (39.6%), within 3 weeks in 12 cases (25%), and within 4 weeks in 7 cases (14.6%). 9) Success rate of skin graft was over 90% in 42 cases (87.6%), and 70∼90% was 5 cases (10.4%).
白鼠에서 化學藥品으로 因한 火傷面의 水浴療法의 實驗的 硏究
丁銓殷 고려대학교 의과대학 1977 고려대 의대 잡지 Vol.14 No.2
Accidental contact with chemicals, or their misuse, is prominent among the course of injury and death, and constitutes one of the potential hazards of our modern life. Most of the skin burns are around the face, neck, chest, and upper extremity; often the eyes are involved resulting in high percentage of corneal burns and frequently total blindness. The present mode of treatment for a chemical burn, such as from lye(NaOH) or HCL, is continuous copious irrigation with water. Author performed experimental studies in 120 mice with the effect of hydrotherapy on the clinical course and pH of experimental cutaneous chemical burns. Following results were observed; 1. Sk n necrosis and eschar formation were more severe in those groups which were irrigated later time after burn. 2. The HCL groups displayed rapidly progressive burn in extent immediately after burn but total degree of eschars were less than the alkali groups. Conversely, in the alkali groups, burns were deceptive; at first effect appeared slight but they progressed seriously by direct extension. 3. Histological examination of burned area revealed the more prominent changes in those groups burned with alkali (NaOH) and irrigated later time. 4. Changes of cutaneous pH of burned area showed the more sever pH aberration in the NaOH groups. Both groups in the NaOH and the HCL revealed the more severe pH changes in those groups washed later time. 5. The mortality rate in the NaOH groups was higher than the HCL groups.