“Social Impact : 아젠다 중심 배분사업의 성과관리”

신용규 한국사회복지행정학회 2016 한국사회복지행정학회 학술대회 자료집 Vol.2016 No.4

Influences of Divalent Cations and Membrane Phosphorylation Inhibitors on $Na^+-Ca^{++}$ Exchange in Synaptosomes

신용규,이정수,이광수,Shin, Yong-Kyoo,Lee, Chung-Soo,Lee, Kwang-Soo The Korean Society of Pharmacology 1988 대한약리학잡지 Vol.24 No.2

소듐에 의한 칼슘의 유리는 verapamil, TTX, TEA의 영향을 받지 않았다. $100\;{\mu}M\;Cd6{++}$과 $Zn^{++}$은 소듐에 의한 칼슘 유출을 유의하게 억제하였다. $Cd^{++}$은 $Ki\;100\;{\mu}M\;Cd6{++}$로써 비상경적으로 소듐-칼슘 교환이동을 억제하였다. $Cd^{++}$은 SH기의 산화를 초래하였으나, $Zn^{++}$은 거의 영향을 나타내지 않았다. $Cd^{++}$과 $Zn^{++}$은 $Na^+-Ca^{++}$ ATPase를 효과적으로 억제하였으나 $Ca^{++}-Mg^{++}$ ATPase를 약간 억제시켰다. Carbonyl cyanide chlorophenylhydrazone, 2,4-dinitrophenol과 sodium arsenate는 소듐에 의한 칼슘 유리를 촉진하였다. Dibucaine과 oligomycin은 소듐에 의한 칼슘의 유리를 약간 억제하였으나, 이에 반하여 ouabain은 약간 촉진하였다. 이상의 실험 결과로부터 신경 세포막에서의 소듐-칼슘 교환은 이온 통로를 통하여 이루어지지 않을 것으로 시사되었다. 소듐-칼슘 교환이동은 $Cd^{++}$에 민감하게 억제되고 이 이동기전에 synaptosome막의 SH기가 관여할 것으로 사료되었다. 또한 소듐-칼슘 교환은 세포막 단백질 성분의 인산화 반응 동안에 억압될 것으로 추정되었다. Verapamil, tetrodotoxin and tetraethylammonium chloride in the stated amount did not affect the $Na^{++}$ induced $Ca^{++}$ release. $Cd^{++}$ and $Zn^{++}$ significantly inhibited the $Na^{++}$ induced $Ca^{++}$ release. $Mn^{++}$ also inhibited $Na^+-Ca^{++}$ exchange. $Cd^{++}$ inhibited $Na^+-Ca^{++}$ exchange noncompetitively with an apparent inhibition constant (Ki) of $100\;{\mu}M$. $Cd^{++}$ caused loss of sulfhydryl group, whereas $Zn^{++}$ did not show any significant effect. $Cd^{++}$ and $Zn^{++}$ effectively inhibited $Na^+-Ca^{++}$ ATPase and slightly inhibited $Ca^{++}-Mg^{++}$ ATPase. Carbonyl cyanide chlorophenylhydrazone, 2,4-dinitrophenol and sodium arsenate stimulated the $Na^{++}$ induced $Ca^{++}$ release. Dibucaine and oligomycin slightly inhibited it. The results suggest that the $Na^+-Ca^{++}$ exchange on the synaptosomal plasma membrane may be not accomplished by ion channels. The $Na^+-Ca^{++}$ exchange is sensitively inhibited by $Cd^{++}$ and this transport process appears to be partially regulated by sulfhydryl groups of the synaptosomal plasma membrane. It is also postulated that $Na^+-Ca^{++}$ exchange is suppressed during the phosphorylation reaction of protein component on the neuronal membrane.

[토론문] 사회복지기관 혁신의 가치와 방향에 관련하여

신용규 한국사회복지행정학회 2018 한국사회복지행정학회 학술대회 자료집 Vol.2018 No.4

[토론문 3] 「환경변화에 따른 지역사회복지실천의 발전과 과제」 토론문

신용규 한국지역사회복지학회 2015 한국지역사회복지학회 학술대회 Vol.2015 No.12

“지역사회복지전달체계의 문제점과 개선과제” 토론

신용규 한국지역사회복지학회 2011 한국지역사회복지학회 학술대회 Vol.2011 No.-

습식법으로 제조한 수산화아파타이트 분말의 소결과 그 미세구조에 미치는 Ca/P몰비의 영향

신용규,정형진,김병호 한국세라믹학회 1989 한국세라믹학회지 Vol.26 No.1

Hydroxyapatite powders were syntehsized by the reaction of Ca(NO3)2.4H2O and (NH4)2HPO4 in aqueous solution. The effect of the Ca/P mole ratio in the starting solution on the sintering of the powders and its microstructure was studied. When the Ca/P mole ratio in the starting solution was 1.69, the relative density of the sintered bodies was more than 95%. The sinterability was decreased as the Ca/P mole ratio in the starting solution was increased (Ca/P mole ratio >1.67). Hydroxyapatite sintered bodies obtained from the Ca/P mole ratio=1.69 had very excellent bending strength. The best bending strength was obtained at 110$0^{\circ}C$ and its value was 1220kg/$\textrm{cm}^2$. The average grain size was 0.277${\mu}{\textrm}{m}$. Most of sintered bodies were almost shown 100% hydroxyapatite phase. However, in case of the Ca/P mole ratio=1.64 hydroxyapatite was decomposed to $\alpha$-whitlockite above 120$0^{\circ}C$.

‘지역사회의 민관복지 거버넌스 활동과 사회복지협의회의 역할과 과제’에 관한 토론

신용규 한국지역사회복지학회 2013 한국지역사회복지학회 학술대회 Vol.2013 No.-

청소년 범죄 기사 내용 분석

신용규,나철,이길홍 중앙대학교 의과대학 의과학연구소 1997 中央醫大誌 Vol.22 No.4

The present study was performed to identify the socio-psychiatric aspects of adolescent criminal offences reported on daily newspapers and to use them as basic materials for prevention of adolescent criminal offences. The author analysed 609 cases of adolescent criminal offence who reported on Dong-a Ilbo and Chung-Cheong Ilbo, from 1991 to 1995. The total numbers of cases were 609, including 573 males and 36 females. In data analysis, the subjects were devided into three subgroups as the student group(221 cases), the working group(70 cases), and the jobless group (318 cases). and the result of the study were as follows. 1. The cases of adolescent criminal offences were more common in male. Their mean ages were the youngest in the student in contrast to late subgroup of the working or the jobless. 2. The antisocial personality was the most common in the jobless, while the dramatic cluster including the borderline or masochistic personality was more prevalent in the working, and the anxious cluster was more in the student. In psycho-social stressors, the student was suffered from various stress in school, home and their social life, while the working showed more serious stress in their hetero-sexual and business life, or more experienced maladjustment in their social and job life, and the jobless group showed more stressful burden due to economical problems, or more experienced maladjustment in their family life. 3. In subtypes of criminal offences, violence, fatal assult, fatal injury, parricide, and their or group offences were more common in the student, while murder, rape and raising the penalty or solitary offences were more frequently observed in the working, and felony was the most prominent offence in the jobless. 4. The incidence of student's offences reported in daily newspapers was remarkably increased, while those of the working or the jobless were decreased. The most vulnerable time of criminal offence in adolescents was from 7-12 PM, and these trends were prominent in the jobless compared with the student in afternoon, and the working in midnight. 5. In motivation of crimes, the psychological conflicts were the most in the student, while the curiosity, the various personality problems, and the heterosexual conflicts were common in the working, and the economical problems or the absence of motivations were prominent in the jobless. 6. In the tools of crime, the sharp materials were the most ones in the student compared with the fists, knives or guns in the working, and the absence of tools in the jobless. In the methods of crime, the latent aggression or physical aggression were the most ones in the student, compared with the forced aggression or direct aggression in the working. 7. In terms of accompanied person participating in criminal offence, group offence was prevalent(60.9%). The numbers of accompanied persons were more than 4 persons in the student, compared with the 2 persons in the working group, and the 1 person in the jobless. In the age ranges of accompanied persons, the student showed the youngest, while the jobless showed the oldest ones. 8. Males(63.2%) were more common in victims of adolescent criminal offences, about 40% of victims was the absence of job, and adults older than 21 years old(34.6%) was the most prevalent, followed by children younger than 11 years old(21.8%). Most of the victims in the student were their friends, lovers or parent with minor injury, while those in the working were passengers with more serious injury. The 67.8% of abusers was unknown persons with victims, and these trends were prominent in the jobless compared with more known persons in the student. 9. In the characteristics of the abuser, the working used more various psychoactive substances or alcohols, and more frequently experienced hallucination or delusion at the time of criminal offence compared with the other groups.

친환경 쌀 생산을 위한 포트육묘 이앙의 경제성 분석

신용규,최인영,권영립,문영훈,최동칠,이왕휴 한국작물학회 2012 한국작물학회지 Vol.57 No.4

친환경 식품이 소비자의 마음을 사로잡으면서 농업의 목표가 생산성 유지 및 향상과 환경의 질을 보존하는 새로운 패러다임으로 변화하고 있다. 따라서 환경친화적 농업(environmentally sound agriculture)이 강조되면서 친환경쌀 생산단지에서 공동으로 이용하고 있는 포트육묘 재배가 농가관행 산파육묘 재배에 비해 얼마나 효율적인지 경제성을 분석한 결과는 다음과 같다. 1. 포트육묘 이앙은 관행이앙 방법에 비해 이앙모판, 파종 및 이앙기 등의 가격이 245% 높았다. 따라서 감가상각비 역시 관행농법에 비해 포트육묘 이앙에서 1.9배 높았다. 2. 10a 당 투입된 노동시간, 노동력 및 비용은 포트육묘 이앙재배에서 각각 13%, 4% 높았다. 그러나 이앙 및 재배에 투입되는 농자재는 종자 및 상토비를 각각 44.0%와 49.2% 절감할 수 있기 때문에 관행농법 대비 4.4% 낮았다. 3. 또한, 포트육묘 이앙재배는 관행 산파육묘 이앙재배에 비해 수량증수에 의한 조수입의 증가(6.7%)와 이앙 후 초기 활착이 빠르고, 성묘이앙으로 초기생육이 양호하여 잡초방제에 유리한 점은 친환경 벼 재배에 적합한 요인으로 작용하였다. 4. 10a 당 육묘와 이앙단계에서의 경영비는 포트육묘 이앙재배에서 229.8% 높았으나 정부에서 80% 기기보조가 된 경우 관행 산파육묘 이앙재배 대비 경영비가 45.4% 절감되었다. In the new changing scenario, the goal of agriculture is shifting from traditional to sustainable and environment-friendly agriculture. Therefore, in this experiment, we analyzed economic efficiency of two methods of rice cultivation i.e. new cultural metIn the new changing scenario, the goal of agriculture is shifting from traditional to sustainable and environment-friendly agriculture. Therefore, in this experiment, we analyzed economic efficiency of two methods of rice cultivation i.e. new cultural method and conventional method, at farmers' fields. In the new cultural method, cost of materials and machines (rice-transplanting and sowing machine) was found 245% higher than the conventional method. Depreciation of cost and working hours were also higher in the new cultural method by 1.9 and 1.1 time, respectively. However, cost of seeds and seedbed soil were 44.0% and 49.2% lower and total material cost was 4.4% lower than the conventional method. In the new cultural method, overall working cost of nursery raising and transplanting per 10a was 229.8% higher than the conventional method. However, in spite of high input cost, yield of rice in new cultural method was higher by 6.7% than the conventional method. Our results showed that new cultural method was better than the conventional method except the input cost. If government provide 80% subsidy for machine cost then its input cost will be reduced by 45.4% than the conventional method.

당뇨병성 방광병증에서 당뇨의 유병기간에 따른 약물치료 효과 비교

신용규,박용일,조성룡 대한비뇨의학회 2002 Investigative and Clinical Urology Vol.43 No.2